AZ-628 Gene Set

Dataset LINCS KinomeScan Kinase Inhibitor Targets
Category physical interactions
Type small molecule
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Genes

29 kinases inhibited by the AZ-628 small molecule from the KinomeScan Kinase Inhibitor Targets dataset.

Symbol Name Standardized Value
CIT citron rho-interacting serine/threonine kinase 1.36211
CSF1R colony stimulating factor 1 receptor 1.36211
RET ret proto-oncogene 1.35325
FLT4 fms-related tyrosine kinase 4 1.35325
LYN LYN proto-oncogene, Src family tyrosine kinase 1.34449
EPHB4 EPH receptor B4 1.34449
SRC SRC proto-oncogene, non-receptor tyrosine kinase 1.31878
LCK LCK proto-oncogene, Src family tyrosine kinase 1.3104
BLK BLK proto-oncogene, Src family tyrosine kinase 1.28583
EPHB1 EPH receptor B1 1.28583
EPHA5 EPH receptor A5 1.28583
CSK c-src tyrosine kinase 1.26991
EPHA8 EPH receptor A8 1.20271
RAF1 Raf-1 proto-oncogene, serine/threonine kinase 1.18873
EPHB6 EPH receptor B6 1.18186
FRK fyn-related Src family tyrosine kinase 1.15523
HCK HCK proto-oncogene, Src family tyrosine kinase 1.1361
EPHA2 EPH receptor A2 1.12988
TNIK TRAF2 and NCK interacting kinase 1.11767
FYN FYN proto-oncogene, Src family tyrosine kinase 1.10576
YES1 YES proto-oncogene 1, Src family tyrosine kinase 1.05057
EPHA3 EPH receptor A3 1.02553
TXK TXK tyrosine kinase 1.00208
ZAK sterile alpha motif and leucine zipper containing kinase AZK 0.963557
RIPK2 receptor-interacting serine-threonine kinase 2 0.944052
MINK1 misshapen-like kinase 1 0.936602
SRMS src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites 0.929345
EPHA1 EPH receptor A1 0.850157
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 0.850157