| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | AZD-7648 perturbation in C-33 A cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the AZD-7648_C-33 A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ZNF608 | zinc finger protein 608 | 0.105658 |
| COL5A2 | collagen, type V, alpha 2 | 0.0907872 |
| DST | dystonin | 0.0899208 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0800719 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0781314 |
| JMJD1C | jumonji domain containing 1C | 0.0778299 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.0658945 |
| VCL | vinculin | 0.0628756 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0598637 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0549742 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0543479 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0541701 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0539423 |
| NFIA | nuclear factor I/A | 0.0453908 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.0442935 |
| SMYD3 | SET and MYND domain containing 3 | 0.040689 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0384691 |
| ATG10 | autophagy related 10 | 0.0374688 |
| ZNF638 | zinc finger protein 638 | 0.0366754 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0366493 |
| OGA | O-GlcNAcase | 0.0360907 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0356419 |
| ZC3H12B | zinc finger CCCH-type containing 12B | 0.0354679 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0342545 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0333445 |
| BRD2 | bromodomain containing 2 | 0.0332832 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0330742 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | 0.032705 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0325814 |
| BNC2 | basonuclin 2 | 0.0325204 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0324994 |
| BAZ2B | bromodomain adjacent to zinc finger domain, 2B | 0.0324033 |
| ZNF644 | zinc finger protein 644 | 0.0321979 |
| CCDC88A | coiled-coil domain containing 88A | 0.031963 |
| SOX5 | SRY (sex determining region Y)-box 5 | 0.0319345 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0318114 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.0315549 |
| SRSF4 | serine/arginine-rich splicing factor 4 | 0.0314756 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0311805 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0307545 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0306523 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0305949 |
| H1-0 | H1.0 linker histone | 0.0305801 |
| JUN | jun proto-oncogene | 0.03003 |
| CUL3 | cullin 3 | 0.0300034 |
| HOMER1 | homer scaffolding protein 1 | 0.0299882 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0297149 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | 0.0296904 |
| PNN | pinin, desmosome associated protein | 0.0296866 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | 0.0293668 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0293005 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0292873 |
| MED13 | mediator complex subunit 13 | 0.0292151 |
| HMGB2 | high mobility group box 2 | 0.0291864 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0286881 |
| CENPE | centromere protein E, 312kDa | 0.0283828 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0282322 |
| KIAA1328 | KIAA1328 | 0.0280281 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0280081 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0280012 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0279803 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0276187 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.0275825 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0274437 |
| ASPH | aspartate beta-hydroxylase | 0.027378 |
| TET2 | tet methylcytosine dioxygenase 2 | 0.0273115 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0269903 |
| RIGI | RNA sensor RIG-I | 0.0267262 |
| SHROOM3 | shroom family member 3 | 0.0266437 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0265738 |
| BRD4 | bromodomain containing 4 | 0.0260403 |
| MAGI3 | membrane associated guanylate kinase, WW and PDZ domain containing 3 | 0.0259068 |
| CABIN1 | calcineurin binding protein 1 | 0.0256831 |
| VMP1 | vacuole membrane protein 1 | 0.025637 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0254243 |
| NKTR | natural killer cell triggering receptor | 0.0251733 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0251555 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0250811 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0249891 |
| ANKRD36C | ankyrin repeat domain 36C | 0.0248162 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0247379 |
| SSH2 | slingshot protein phosphatase 2 | 0.0245025 |
| PCNX4 | pecanex 4 | 0.0243847 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.02419 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0240998 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | 0.0240265 |
| NBEA | neurobeachin | 0.0239958 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0239512 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0238071 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0237609 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.0236727 |
| HELZ | helicase with zinc finger | 0.0236675 |
| CELF2 | CUGBP, Elav-like family member 2 | 0.0235464 |
| PIK3R3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) | 0.0234842 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | 0.0234692 |
| NBEAL1 | neurobeachin-like 1 | 0.0233947 |
| SMAD6 | SMAD family member 6 | 0.0233109 |
| TPR | translocated promoter region, nuclear basket protein | 0.0232938 |
| RBM33 | RNA binding motif protein 33 | 0.0231833 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | 0.0231667 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.255167 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | -0.183836 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | -0.133248 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.126254 |
| NPAS3 | neuronal PAS domain protein 3 | -0.113989 |
| TENM3 | teneurin transmembrane protein 3 | -0.103061 |
| ACTG1 | actin gamma 1 | -0.0960899 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0882227 |
| HMGA1 | high mobility group AT-hook 1 | -0.0875448 |
| RAD51B | RAD51 paralog B | -0.0776548 |
| RPLP1 | ribosomal protein, large, P1 | -0.0745639 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.069899 |
| TMSB10 | thymosin beta 10 | -0.0667725 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0637719 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0518837 |
| VIM | vimentin | -0.0500284 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0479171 |
| RPL12 | ribosomal protein L12 | -0.0458095 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0432939 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0431579 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | -0.0421952 |
| NR5A2 | nuclear receptor subfamily 5, group A, member 2 | -0.0420938 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | -0.04195 |
| GJA1 | gap junction protein, alpha 1, 43kDa | -0.0418616 |
| RPL11 | ribosomal protein L11 | -0.0404109 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0398709 |
| RPS24 | ribosomal protein S24 | -0.0397867 |
| RPS25 | ribosomal protein S25 | -0.0387992 |
| RPLP2 | ribosomal protein, large, P2 | -0.0382518 |
| RPS13 | ribosomal protein S13 | -0.0359438 |
| PKM | pyruvate kinase, muscle | -0.0351697 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0350096 |
| RPS23 | ribosomal protein S23 | -0.0348964 |
| RPS5 | ribosomal protein S5 | -0.0348549 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0345322 |
| RPL7A | ribosomal protein L7a | -0.0343641 |
| LDHA | lactate dehydrogenase A | -0.034281 |
| RPS11 | ribosomal protein S11 | -0.0340658 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0339775 |
| HMGB1 | high mobility group box 1 | -0.0330907 |
| RPS19 | ribosomal protein S19 | -0.0329351 |
| RPS28 | ribosomal protein S28 | -0.0327754 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0325617 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0319885 |
| RPS14 | ribosomal protein S14 | -0.0319527 |
| RPL23 | ribosomal protein L23 | -0.031189 |
| RPS21 | ribosomal protein S21 | -0.0311836 |
| RPL35A | ribosomal protein L35a | -0.0305842 |
| PTMA | prothymosin, alpha | -0.0304764 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.030377 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.0302022 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0299953 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0298029 |
| ATP9A | ATPase, class II, type 9A | -0.0297735 |
| RPL9 | ribosomal protein L9 | -0.0288984 |
| RPS8 | ribosomal protein S8 | -0.028778 |
| TPM4 | tropomyosin 4 | -0.028508 |
| RPS16 | ribosomal protein S16 | -0.0283091 |
| ZFP64 | ZFP64 zinc finger protein | -0.0282531 |
| RPL36A | ribosomal protein L36a | -0.028219 |
| RPLP0 | ribosomal protein, large, P0 | -0.0282015 |
| GART | phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase | -0.0281434 |
| PFN1 | profilin 1 | -0.0281026 |
| RPS29 | ribosomal protein S29 | -0.0280305 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0278976 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0272135 |
| MAP4 | microtubule-associated protein 4 | -0.0271911 |
| EMP1 | epithelial membrane protein 1 | -0.0270508 |
| RPL27A | ribosomal protein L27a | -0.0267192 |
| ZNF207 | zinc finger protein 207 | -0.0264082 |
| RPL31 | ribosomal protein L31 | -0.0258273 |
| RPS15 | ribosomal protein S15 | -0.0254843 |
| RPS10 | ribosomal protein S10 | -0.0254484 |
| TUBA1B | tubulin, alpha 1b | -0.0250285 |
| SOX2 | SRY (sex determining region Y)-box 2 | -0.0248453 |
| TRAP1 | TNF receptor-associated protein 1 | -0.0246828 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0246785 |
| SYNE1 | spectrin repeat containing, nuclear envelope 1 | -0.0246586 |
| RPS12 | ribosomal protein S12 | -0.0244375 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0243971 |
| RACK1 | receptor for activated C kinase 1 | -0.0243607 |
| S100A9 | S100 calcium binding protein A9 | -0.0243285 |
| RPL28 | ribosomal protein L28 | -0.0236411 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0232494 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0232474 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0229365 |
| UBE2V1 | ubiquitin-conjugating enzyme E2 variant 1 | -0.0228999 |
| FAT1 | FAT atypical cadherin 1 | -0.0228397 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0227669 |
| CCDC138 | coiled-coil domain containing 138 | -0.0227194 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0226895 |
| RPL37 | ribosomal protein L37 | -0.0221811 |
| FAU | Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed | -0.0221761 |
| CADM2 | cell adhesion molecule 2 | -0.0221459 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | -0.0219828 |
| TOM1L2 | target of myb1-like 2 (chicken) | -0.0218993 |
| RPL37A | ribosomal protein L37a | -0.0218121 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.021552 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0215308 |
| RPL8 | ribosomal protein L8 | -0.0214278 |
