| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | AZD-8055 perturbation in C-33 A cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the AZD-8055_C-33 A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SLIT2 | slit homolog 2 (Drosophila) | 0.221336 |
| RPS6 | ribosomal protein S6 | 0.159583 |
| NEBL | nebulette | 0.137277 |
| RPS2 | ribosomal protein S2 | 0.118634 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.102163 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.100423 |
| TENM3 | teneurin transmembrane protein 3 | 0.0956196 |
| ZNF608 | zinc finger protein 608 | 0.0951697 |
| JMJD1C | jumonji domain containing 1C | 0.0945154 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0920791 |
| TOX | thymocyte selection-associated high mobility group box | 0.0884777 |
| RPL11 | ribosomal protein L11 | 0.0874966 |
| COL5A2 | collagen, type V, alpha 2 | 0.0791246 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.0767941 |
| CADM2 | cell adhesion molecule 2 | 0.0729263 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0728912 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0725859 |
| CELF2 | CUGBP, Elav-like family member 2 | 0.0724568 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | 0.0718507 |
| RPS8 | ribosomal protein S8 | 0.0693923 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.06905 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.067666 |
| RPLP0 | ribosomal protein, large, P0 | 0.0643822 |
| DST | dystonin | 0.0642528 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0639675 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0639069 |
| VMP1 | vacuole membrane protein 1 | 0.0630039 |
| SIK2 | salt-inducible kinase 2 | 0.0622528 |
| RPS3 | ribosomal protein S3 | 0.0590277 |
| NBEAL1 | neurobeachin-like 1 | 0.0589053 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.0587945 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0577565 |
| CENPF | centromere protein F, 350/400kDa | 0.0575701 |
| RPL37 | ribosomal protein L37 | 0.0551396 |
| RPS12 | ribosomal protein S12 | 0.05311 |
| PCNX4 | pecanex 4 | 0.0530137 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0524735 |
| RPL7 | ribosomal protein L7 | 0.0522873 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0514407 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0502034 |
| CUX1 | cut-like homeobox 1 | 0.0493003 |
| RPL37A | ribosomal protein L37a | 0.0485915 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0476531 |
| SKIL | SKI-like proto-oncogene | 0.0474626 |
| RACK1 | receptor for activated C kinase 1 | 0.0468311 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | 0.046666 |
| SEMA3D | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D | 0.0460553 |
| RPL13A | ribosomal protein L13a | 0.0455986 |
| CEP112 | centrosomal protein 112kDa | 0.0455025 |
| MKI67 | marker of proliferation Ki-67 | 0.0454084 |
| RPS13 | ribosomal protein S13 | 0.0444186 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0423468 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0421914 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.041537 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.0411576 |
| WLS | wntless Wnt ligand secretion mediator | 0.0410429 |
| ATF4 | activating transcription factor 4 | 0.0407997 |
| RPL26 | ribosomal protein L26 | 0.0407026 |
| RPL9 | ribosomal protein L9 | 0.03962 |
| ACTG1 | actin gamma 1 | 0.0392577 |
| RPL12 | ribosomal protein L12 | 0.0390071 |
| RPLP1 | ribosomal protein, large, P1 | 0.0388499 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.0388393 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0379515 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0378656 |
| BPTF | bromodomain PHD finger transcription factor | 0.0377721 |
| RPL19 | ribosomal protein L19 | 0.0376276 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | 0.0373794 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0372689 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.037006 |
| RPS16 | ribosomal protein S16 | 0.0365121 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.036177 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.0358879 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0355611 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0355391 |
| GOLGB1 | golgin B1 | 0.0353376 |
| RPL5 | ribosomal protein L5 | 0.0350658 |
| RPL31 | ribosomal protein L31 | 0.0344287 |
| HIVEP1 | human immunodeficiency virus type I enhancer binding protein 1 | 0.0344268 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0341151 |
| RPS18 | ribosomal protein S18 | 0.0337893 |
| RPS23 | ribosomal protein S23 | 0.0333809 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0327958 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.0327655 |
| BNC2 | basonuclin 2 | 0.0327174 |
| AHI1 | Abelson helper integration site 1 | 0.0326915 |
| ADNP | activity-dependent neuroprotector homeobox | 0.03254 |
| RPS25 | ribosomal protein S25 | 0.0322096 |
| RPL28 | ribosomal protein L28 | 0.0320833 |
| SIK3 | SIK family kinase 3 | 0.0317314 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.031516 |
| UBAP2 | ubiquitin associated protein 2 | 0.0313789 |
| KMT2A | lysine (K)-specific methyltransferase 2A | 0.0313162 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0311866 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0310914 |
| TBL1X | transducin (beta)-like 1X-linked | 0.0309554 |
| MATR3 | matrin 3 | 0.0304945 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0304513 |
| RPS17 | ribosomal protein S17 | 0.0303616 |
| RPS5 | ribosomal protein S5 | 0.0303256 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0903798 |
| UBC | ubiquitin C | -0.0896447 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0860948 |
| NPAS3 | neuronal PAS domain protein 3 | -0.0820659 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | -0.0819692 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0654922 |
| TMSB10 | thymosin beta 10 | -0.0574293 |
| RAD51B | RAD51 paralog B | -0.0528802 |
| ENO1 | enolase 1, (alpha) | -0.0523139 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0503577 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0490143 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0473753 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.045107 |
| SMYD3 | SET and MYND domain containing 3 | -0.0441745 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | -0.0413808 |
| RPS27A | ribosomal protein S27a | -0.0411022 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0410856 |
| CALU | calumenin | -0.0409349 |
| RIGI | RNA sensor RIG-I | -0.038877 |
| RBM25 | RNA binding motif protein 25 | -0.0380384 |
| LDHA | lactate dehydrogenase A | -0.0376963 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0361734 |
| WDR45B | WD repeat domain 45B | -0.0338408 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.033392 |
| HMGB1 | high mobility group box 1 | -0.0324449 |
| SLF1 | SMC5-SMC6 complex localization factor 1 | -0.0322834 |
| BLTP2 | bridge-like lipid transfer protein family member 2 | -0.0319125 |
| XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) | -0.031789 |
| NUP58 | nucleoporin 58 | -0.0317384 |
| TXNRD1 | thioredoxin reductase 1 | -0.0316588 |
| KIAA1958 | KIAA1958 | -0.0311421 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0308916 |
| PGK1 | phosphoglycerate kinase 1 | -0.0301723 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0300186 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0299357 |
| OGA | O-GlcNAcase | -0.0290265 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.028893 |
| PNPT1 | polyribonucleotide nucleotidyltransferase 1 | -0.0287219 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0284684 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0284003 |
| WDPCP | WD repeat containing planar cell polarity effector | -0.0283291 |
| PTBP2 | polypyrimidine tract binding protein 2 | -0.0278597 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0275456 |
| HELZ | helicase with zinc finger | -0.0270558 |
| ZFP64 | ZFP64 zinc finger protein | -0.0269195 |
| TENM2 | teneurin transmembrane protein 2 | -0.0266881 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | -0.026602 |
| VPS13A | vacuolar protein sorting 13 homolog A (S. cerevisiae) | -0.0263078 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.0262074 |
| YBX1 | Y box binding protein 1 | -0.0258288 |
| PIAS2 | protein inhibitor of activated STAT, 2 | -0.0256999 |
| FASN | fatty acid synthase | -0.0254293 |
| DIDO1 | death inducer-obliterator 1 | -0.02521 |
| B2M | beta-2-microglobulin | -0.0251813 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0246776 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0246736 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0244911 |
| NBAS | neuroblastoma amplified sequence | -0.0243979 |
| UBE2G1 | ubiquitin-conjugating enzyme E2G 1 | -0.0242924 |
| RTN4 | reticulon 4 | -0.0242372 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0241606 |
| HACE1 | HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1 | -0.0241519 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.024114 |
| ANK2 | ankyrin 2, neuronal | -0.0240608 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0238303 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | -0.0237433 |
| SEC63 | SEC63 homolog (S. cerevisiae) | -0.0234471 |
| ATRN | attractin | -0.0234386 |
| CCDC47 | coiled-coil domain containing 47 | -0.0227129 |
| KDM4B | lysine (K)-specific demethylase 4B | -0.0226199 |
| RBM33 | RNA binding motif protein 33 | -0.0225615 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0225215 |
| ZNF292 | zinc finger protein 292 | -0.0224864 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0223033 |
| CHSY1 | chondroitin sulfate synthase 1 | -0.022291 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | -0.0221916 |
| PTMA | prothymosin, alpha | -0.0221694 |
| PRELID2 | PRELI domain containing 2 | -0.0220007 |
| FAM168A | family with sequence similarity 168, member A | -0.021966 |
| CCT8 | chaperonin containing TCP1, subunit 8 (theta) | -0.0218223 |
| MSI2 | musashi RNA-binding protein 2 | -0.0216546 |
| GRID2 | glutamate receptor, ionotropic, delta 2 | -0.0213982 |
| FAM162A | family with sequence similarity 162, member A | -0.0209692 |
| OLA1 | Obg-like ATPase 1 | -0.0209108 |
| MARS1 | methionyl-tRNA synthetase 1 | -0.0208931 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0208387 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0208133 |
| TUBB | tubulin, beta class I | -0.0207882 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0207655 |
| ACBD6 | acyl-CoA binding domain containing 6 | -0.0205856 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | -0.0204355 |
| UBE2V1 | ubiquitin-conjugating enzyme E2 variant 1 | -0.0203025 |
| CABIN1 | calcineurin binding protein 1 | -0.0202851 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | -0.0200207 |
| NARS1 | asparaginyl-tRNA synthetase 1 | -0.019946 |
| FDFT1 | farnesyl-diphosphate farnesyltransferase 1 | -0.019877 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0197396 |
| RNMT | RNA (guanine-7-) methyltransferase | -0.0196891 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | -0.0196844 |
| SALL4 | spalt-like transcription factor 4 | -0.0195606 |
