| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | AZD-8055 perturbation in CFPAC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the AZD-8055_CFPAC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.194255 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.185432 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0980346 |
| SMAD3 | SMAD family member 3 | 0.0894989 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0876903 |
| KRT19 | keratin 19, type I | 0.086327 |
| LAMC2 | laminin, gamma 2 | 0.0792685 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0765531 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.074157 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0706647 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0698864 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0676186 |
| NRG3 | neuregulin 3 | 0.0654475 |
| LAMB3 | laminin, beta 3 | 0.0649333 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0646661 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0643363 |
| APP | amyloid beta (A4) precursor protein | 0.0631073 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0613155 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.060272 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0565105 |
| NDRG1 | N-myc downstream regulated 1 | 0.0546191 |
| LAMA4 | laminin, alpha 4 | 0.0523128 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0514467 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0508167 |
| CDCP1 | CUB domain containing protein 1 | 0.0483138 |
| SGMS2 | sphingomyelin synthase 2 | 0.0471875 |
| RAI14 | retinoic acid induced 14 | 0.0469549 |
| MCL1 | myeloid cell leukemia 1 | 0.0469313 |
| MYO1E | myosin IE | 0.0464679 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0464056 |
| NRG1 | neuregulin 1 | 0.0450648 |
| VEGFA | vascular endothelial growth factor A | 0.0447246 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0446268 |
| CMIP | c-Maf inducing protein | 0.0432824 |
| HMGA1 | high mobility group AT-hook 1 | 0.0424613 |
| GOLGB1 | golgin B1 | 0.0418939 |
| APOL1 | apolipoprotein L, 1 | 0.0414196 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0408846 |
| PLEC | plectin | 0.0406585 |
| PATJ | PATJ crumbs cell polarity complex component | 0.0403146 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0398469 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0394775 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0388904 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0386797 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0383273 |
| SEPTIN9 | septin 9 | 0.0381347 |
| FAM3C | family with sequence similarity 3, member C | 0.0380386 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0380112 |
| DTNA | dystrobrevin, alpha | 0.0376849 |
| SVIL | supervillin | 0.0371646 |
| DSG2 | desmoglein 2 | 0.0370964 |
| FAM107B | family with sequence similarity 107, member B | 0.0366516 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0345797 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0343447 |
| NAV2 | neuron navigator 2 | 0.0334943 |
| HMGA2 | high mobility group AT-hook 2 | 0.0333055 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0331859 |
| PRKCA | protein kinase C, alpha | 0.0331762 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0326568 |
| PARD3 | par-3 family cell polarity regulator | 0.0326297 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.031972 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0317069 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0309206 |
| ANO6 | anoctamin 6 | 0.0302378 |
| TGM2 | transglutaminase 2 | 0.0298295 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0297065 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.0296985 |
| DSPP | dentin sialophosphoprotein | 0.0295224 |
| CLTC | clathrin, heavy chain (Hc) | 0.0295031 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0294368 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | 0.0292671 |
| NUMB | numb homolog (Drosophila) | 0.0292377 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0291512 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0284847 |
| HDAC9 | histone deacetylase 9 | 0.0283677 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0283014 |
| STC1 | stanniocalcin 1 | 0.0281785 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0281668 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0280731 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0280552 |
| VMP1 | vacuole membrane protein 1 | 0.0277393 |
| BARX2 | BARX homeobox 2 | 0.0271727 |
| MTSS1 | metastasis suppressor 1 | 0.0265954 |
| SGPP2 | sphingosine-1-phosphate phosphatase 2 | 0.0265166 |
| TMEM51 | transmembrane protein 51 | 0.026357 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0260322 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | 0.0256779 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0256375 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.025021 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | 0.0247949 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0247845 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0247472 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0245882 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0245192 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0243898 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.0243241 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.024271 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | 0.0240825 |
| MYO5B | myosin VB | 0.0239067 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.023492 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.210872 |
| TMSB10 | thymosin beta 10 | -0.11042 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0970365 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0837906 |
| FTL | ferritin, light polypeptide | -0.0788989 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0767201 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0722388 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0663733 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0655822 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0640281 |
| FGB | fibrinogen beta chain | -0.0523436 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0505392 |
| CP | ceruloplasmin (ferroxidase) | -0.0500311 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0491993 |
| VIM | vimentin | -0.0485577 |
| PGK1 | phosphoglycerate kinase 1 | -0.0477688 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0471374 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0450459 |
| FAM162A | family with sequence similarity 162, member A | -0.0426665 |
| MT1X | metallothionein 1X | -0.0423137 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0413532 |
| RPL35A | ribosomal protein L35a | -0.0402858 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0393073 |
| ANXA2 | annexin A2 | -0.0387755 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0384804 |
| MMP7 | matrix metallopeptidase 7 | -0.0379653 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0376679 |
| MUC4 | mucin 4, cell surface associated | -0.037623 |
| IER3 | immediate early response 3 | -0.0369362 |
| USP3 | ubiquitin specific peptidase 3 | -0.0354472 |
| RTN4 | reticulon 4 | -0.0353327 |
| ZNF292 | zinc finger protein 292 | -0.0352829 |
| RHEX | regulator of hemoglobinization and erythroid cell expansion | -0.0348697 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | -0.0348572 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0342435 |
| CD47 | CD47 molecule | -0.033734 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0331491 |
| RPLP1 | ribosomal protein, large, P1 | -0.0329369 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0327713 |
| GBP2 | guanylate binding protein 2, interferon-inducible | -0.0324261 |
| TMEM123 | transmembrane protein 123 | -0.0320565 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0317792 |
| GNAS | GNAS complex locus | -0.0306299 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0306131 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.030541 |
| CD2AP | CD2-associated protein | -0.0304783 |
| ACTG1 | actin gamma 1 | -0.0304593 |
| FLNB | filamin B, beta | -0.0303019 |
| FAM13A | family with sequence similarity 13, member A | -0.0301404 |
| RPL23 | ribosomal protein L23 | -0.0298077 |
| RPS6 | ribosomal protein S6 | -0.0296104 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0289474 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0287708 |
| RPS8 | ribosomal protein S8 | -0.0284392 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0282807 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0281393 |
| WDR45B | WD repeat domain 45B | -0.0281311 |
| RPL11 | ribosomal protein L11 | -0.0278465 |
| MKI67 | marker of proliferation Ki-67 | -0.0276076 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0274347 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0273251 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0272978 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0270944 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | -0.0269426 |
| HLA-B | major histocompatibility complex, class I, B | -0.0267387 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.0266592 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.026257 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0261592 |
| OGA | O-GlcNAcase | -0.0260954 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0260537 |
| RAB6A | RAB6A, member RAS oncogene family | -0.025525 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0249752 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0248628 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0247399 |
| RPL37A | ribosomal protein L37a | -0.0246481 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0245404 |
| RPS3 | ribosomal protein S3 | -0.0241027 |
| RPS24 | ribosomal protein S24 | -0.0238317 |
| RPS29 | ribosomal protein S29 | -0.023676 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0235038 |
| INSIG1 | insulin induced gene 1 | -0.02345 |
| WWC1 | WW and C2 domain containing 1 | -0.0234358 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0232612 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0229918 |
| CALR | calreticulin | -0.0226891 |
| RPLP0 | ribosomal protein, large, P0 | -0.0225573 |
| RBM39 | RNA binding motif protein 39 | -0.0223337 |
| RPL19 | ribosomal protein L19 | -0.0222314 |
| NNMT | nicotinamide N-methyltransferase | -0.0222222 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | -0.0221967 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0220255 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0219505 |
| MACC1 | metastasis associated in colon cancer 1 | -0.0219359 |
| MT2A | metallothionein 2A | -0.0218503 |
| TUBB | tubulin, beta class I | -0.0215573 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0213917 |
| CLINT1 | clathrin interactor 1 | -0.0213434 |
| KYNU | kynureninase | -0.021104 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0209454 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.020942 |
