| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | AZD-8055 perturbation in LOX-IMVI cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the AZD-8055_LOX-IMVI drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DTNA | dystrobrevin, alpha | 0.20173 |
| HDAC9 | histone deacetylase 9 | 0.122561 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.107106 |
| LSAMP | limbic system-associated membrane protein | 0.0951392 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0848522 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0824675 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.080914 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0792613 |
| RPS2 | ribosomal protein S2 | 0.0693317 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0670339 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0625114 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0582953 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0575968 |
| ACTG1 | actin gamma 1 | 0.0556627 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0546854 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0534614 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0531771 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0506525 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0481318 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.046519 |
| HMGA2 | high mobility group AT-hook 2 | 0.0462024 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0418699 |
| EFNA5 | ephrin-A5 | 0.0411644 |
| SPAG9 | sperm associated antigen 9 | 0.0402183 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0393713 |
| MARCHF4 | membrane associated ring-CH-type finger 4 | 0.0393513 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0381672 |
| DGKI | diacylglycerol kinase, iota | 0.0361222 |
| NUP58 | nucleoporin 58 | 0.0351429 |
| PRKCE | protein kinase C, epsilon | 0.0348744 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.034659 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0341655 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0340957 |
| IRS2 | insulin receptor substrate 2 | 0.0337274 |
| RPS18 | ribosomal protein S18 | 0.0322624 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0319146 |
| FNIP1 | folliculin interacting protein 1 | 0.0309814 |
| RUNX1 | runt-related transcription factor 1 | 0.0307197 |
| USP34 | ubiquitin specific peptidase 34 | 0.0305987 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0299964 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | 0.0296309 |
| NAV3 | neuron navigator 3 | 0.0287819 |
| RPL7 | ribosomal protein L7 | 0.0282767 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0281679 |
| EPG5 | ectopic P-granules autophagy protein 5 homolog (C. elegans) | 0.0277048 |
| RPL12 | ribosomal protein L12 | 0.0268365 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | 0.0267407 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0264101 |
| CSTB | cystatin B (stefin B) | 0.0251748 |
| ARFGEF3 | ARFGEF family member 3 | 0.0248176 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0247716 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0247338 |
| DENR | density-regulated protein | 0.0244654 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.023689 |
| JMJD1C | jumonji domain containing 1C | 0.0236837 |
| TRIM44 | tripartite motif containing 44 | 0.023139 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0231133 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | 0.0229514 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | 0.0229335 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0219287 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.021911 |
| ADAM32 | ADAM metallopeptidase domain 32 | 0.0215327 |
| SMAP1 | small ArfGAP 1 | 0.0212698 |
| GPHN | gephyrin | 0.0212033 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0208936 |
| APP | amyloid beta (A4) precursor protein | 0.0206765 |
| RPLP0 | ribosomal protein, large, P0 | 0.0203081 |
| PHF3 | PHD finger protein 3 | 0.0202679 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0202043 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0199684 |
| RPS12 | ribosomal protein S12 | 0.0198908 |
| FMNL2 | formin-like 2 | 0.0194759 |
| YBX3 | Y box binding protein 3 | 0.0193944 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0193445 |
| SLC25A26 | solute carrier family 25 (S-adenosylmethionine carrier), member 26 | 0.019082 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0189933 |
| PCBP2 | poly(rC) binding protein 2 | 0.0189627 |
| RPL26 | ribosomal protein L26 | 0.0189278 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0186667 |
| GOLGA4 | golgin A4 | 0.0186584 |
| CAMK2D | calcium/calmodulin-dependent protein kinase II delta | 0.0186125 |
| PTPRB | protein tyrosine phosphatase, receptor type, B | 0.0185526 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.018472 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0184019 |
| CORO1C | coronin, actin binding protein, 1C | 0.0183685 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0183398 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0179762 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 | 0.0177746 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0177405 |
| NGLY1 | N-glycanase 1 | 0.017654 |
| ADTRP | androgen-dependent TFPI-regulating protein | 0.0174468 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0174343 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0173742 |
| GAN | gigaxonin | 0.0171907 |
| CREBRF | CREB3 regulatory factor | 0.0171122 |
| TFRC | transferrin receptor | 0.0170899 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0170835 |
| IPO7 | importin 7 | 0.0169435 |
| ZC3H15 | zinc finger CCCH-type containing 15 | 0.016901 |
| ITSN2 | intersectin 2 | 0.0168822 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.213867 |
| TMSB10 | thymosin beta 10 | -0.172129 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.152146 |
| GPC6 | glypican 6 | -0.134412 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.133329 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.1221 |
| VCL | vinculin | -0.117879 |
| PTMA | prothymosin, alpha | -0.111733 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.100675 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0995392 |
| CDH13 | cadherin 13 | -0.0970031 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.09298 |
| AHNAK | AHNAK nucleoprotein | -0.0883645 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0785668 |
| KIAA1549L | KIAA1549-like | -0.0738247 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0730025 |
| NAV1 | neuron navigator 1 | -0.0712609 |
| FN1 | fibronectin 1 | -0.0711009 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0704991 |
| TPM4 | tropomyosin 4 | -0.0698339 |
| MT2A | metallothionein 2A | -0.066254 |
| PTCHD4 | patched domain containing 4 | -0.0658465 |
| SAMD3 | sterile alpha motif domain containing 3 | -0.0628994 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0603923 |
| RTN4 | reticulon 4 | -0.0584602 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0572539 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0554788 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | -0.0548438 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0540879 |
| C2CD2 | C2 calcium-dependent domain containing 2 | -0.0536896 |
| ADAM19 | ADAM metallopeptidase domain 19 | -0.0501562 |
| TNNC1 | troponin C type 1 (slow) | -0.0497326 |
| RIGI | RNA sensor RIG-I | -0.048133 |
| RNF213 | ring finger protein 213 | -0.0474561 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.047036 |
| SASH1 | SAM and SH3 domain containing 1 | -0.0449796 |
| HAS2 | hyaluronan synthase 2 | -0.0445507 |
| NTM | neurotrimin | -0.0435069 |
| EGR1 | early growth response 1 | -0.0433648 |
| BNC2 | basonuclin 2 | -0.0432468 |
| VEPH1 | ventricular zone expressed PH domain-containing 1 | -0.043182 |
| CTSB | cathepsin B | -0.0426438 |
| RAD51B | RAD51 paralog B | -0.0411117 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0411032 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0399382 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0397998 |
| ANXA2 | annexin A2 | -0.0395758 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0392278 |
| PHACTR1 | phosphatase and actin regulator 1 | -0.0385634 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0385056 |
| FOXP1 | forkhead box P1 | -0.0377982 |
| NLGN1 | neuroligin 1 | -0.0377755 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0373658 |
| PKM | pyruvate kinase, muscle | -0.037278 |
| PTK2 | protein tyrosine kinase 2 | -0.0372518 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0369611 |
| CAVIN1 | caveolae associated protein 1 | -0.0367855 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0365026 |
| ZNF804A | zinc finger protein 804A | -0.0364856 |
| ETV6 | ets variant 6 | -0.0358183 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.0358166 |
| MAP1B | microtubule-associated protein 1B | -0.0356992 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0356547 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | -0.0355314 |
| TXNRD1 | thioredoxin reductase 1 | -0.0354431 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0348223 |
| TENM2 | teneurin transmembrane protein 2 | -0.0347883 |
| ASPH | aspartate beta-hydroxylase | -0.0341094 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0340705 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0337947 |
| VCAN | versican | -0.0337823 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0336858 |
| MKI67 | marker of proliferation Ki-67 | -0.0334798 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0334626 |
| NHSL1 | NHS-like 1 | -0.0334486 |
| NRP2 | neuropilin 2 | -0.03319 |
| PGK1 | phosphoglycerate kinase 1 | -0.0326549 |
| RAI14 | retinoic acid induced 14 | -0.0325078 |
| DIAPH3 | diaphanous-related formin 3 | -0.0323036 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0322981 |
| GNAS | GNAS complex locus | -0.0321986 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | -0.0320245 |
| SMAD3 | SMAD family member 3 | -0.0319493 |
| ARHGAP18 | Rho GTPase activating protein 18 | -0.0314847 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0313992 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0313361 |
| CALD1 | caldesmon 1 | -0.0308003 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0307963 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0304648 |
| RPS19 | ribosomal protein S19 | -0.0304056 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0303679 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0303164 |
| CSMD3 | CUB and Sushi multiple domains 3 | -0.0301317 |
| RPLP1 | ribosomal protein, large, P1 | -0.0299674 |
| PRSS23 | protease, serine, 23 | -0.0298531 |
| MAP4 | microtubule-associated protein 4 | -0.0297652 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.029581 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0293189 |
| TPI1 | triosephosphate isomerase 1 | -0.0291275 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0289678 |
