| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | AZD-8055 perturbation in NCI-H2347 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the AZD-8055_NCI-H2347 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.338658 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.159104 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0905902 |
| LMO7 | LIM domain 7 | 0.0851962 |
| LAMC2 | laminin, gamma 2 | 0.0808534 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0795519 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0763383 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0678709 |
| EFNA5 | ephrin-A5 | 0.0674754 |
| NAV2 | neuron navigator 2 | 0.0611796 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0588009 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0582784 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0557978 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.054901 |
| SMAD3 | SMAD family member 3 | 0.0539244 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0520771 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0519279 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.051571 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0493317 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0491429 |
| DSPP | dentin sialophosphoprotein | 0.046671 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0461443 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0444499 |
| ASPH | aspartate beta-hydroxylase | 0.0441505 |
| DTNA | dystrobrevin, alpha | 0.0438673 |
| PTK2 | protein tyrosine kinase 2 | 0.0438412 |
| DSG2 | desmoglein 2 | 0.043754 |
| MYO5B | myosin VB | 0.0417194 |
| GOLGB1 | golgin B1 | 0.0411509 |
| AHNAK | AHNAK nucleoprotein | 0.0408852 |
| HSPA8 | heat shock 70kDa protein 8 | 0.040629 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0397834 |
| RAI14 | retinoic acid induced 14 | 0.0397646 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.0393204 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0388024 |
| FNIP1 | folliculin interacting protein 1 | 0.0387214 |
| PLEC | plectin | 0.0383222 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0377609 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0353466 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0350743 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 | 0.0349294 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0344706 |
| FAM107B | family with sequence similarity 107, member B | 0.0342428 |
| CANX | calnexin | 0.033036 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0329697 |
| PDLIM5 | PDZ and LIM domain 5 | 0.032549 |
| RCOR1 | REST corepressor 1 | 0.031921 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0317424 |
| ERBIN | erbb2 interacting protein | 0.0314908 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0303256 |
| VGLL3 | vestigial-like family member 3 | 0.0301675 |
| MYO6 | myosin VI | 0.0298959 |
| ANO6 | anoctamin 6 | 0.0298576 |
| FBXO32 | F-box protein 32 | 0.0297092 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0296842 |
| MICAL3 | microtubule associated monooxygenase, calponin and LIM domain containing 3 | 0.0295249 |
| TMF1 | TATA element modulatory factor 1 | 0.0291967 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0290278 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0289972 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0287119 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0282603 |
| APP | amyloid beta (A4) precursor protein | 0.0281796 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | 0.0280352 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0276893 |
| MYO1E | myosin IE | 0.0276156 |
| SVIL | supervillin | 0.0275299 |
| DUSP6 | dual specificity phosphatase 6 | 0.0274735 |
| CLTC | clathrin, heavy chain (Hc) | 0.0269278 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0267485 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0263851 |
| NR3C2 | nuclear receptor subfamily 3, group C, member 2 | 0.0263224 |
| PGBD5 | piggyBac transposable element derived 5 | 0.0263102 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0262811 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0259016 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0257289 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0256371 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0250809 |
| SGMS2 | sphingomyelin synthase 2 | 0.0250208 |
| USP53 | ubiquitin specific peptidase 53 | 0.0249727 |
| MCTP2 | multiple C2 domains, transmembrane 2 | 0.0249616 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0249478 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0248041 |
| TMSB4X | thymosin beta 4, X-linked | 0.0247098 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | 0.0244652 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0243879 |
| ANTXR2 | anthrax toxin receptor 2 | 0.0237486 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0235297 |
| PATJ | PATJ crumbs cell polarity complex component | 0.023516 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0234948 |
| CTBP2 | C-terminal binding protein 2 | 0.023355 |
| SLTM | SAFB-like, transcription modulator | 0.0230761 |
| FGD4 | FYVE, RhoGEF and PH domain containing 4 | 0.0229817 |
| RASA2 | RAS p21 protein activator 2 | 0.0228959 |
| COPA | coatomer protein complex, subunit alpha | 0.0228266 |
| ARRDC3 | arrestin domain containing 3 | 0.0228025 |
| ATXN1 | ataxin 1 | 0.0225508 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.0224733 |
| CD109 | CD109 molecule | 0.0223838 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0223095 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0217602 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.23244 |
| FTL | ferritin, light polypeptide | -0.22937 |
| PTMA | prothymosin, alpha | -0.179853 |
| TMSB10 | thymosin beta 10 | -0.136796 |
| RPL35A | ribosomal protein L35a | -0.0852645 |
| MT2A | metallothionein 2A | -0.0731234 |
| RPS19 | ribosomal protein S19 | -0.0723618 |
| RPLP1 | ribosomal protein, large, P1 | -0.0714413 |
| FN1 | fibronectin 1 | -0.0657375 |
| S100A6 | S100 calcium binding protein A6 | -0.0618054 |
| RPLP2 | ribosomal protein, large, P2 | -0.0596592 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0588447 |
| RPL23 | ribosomal protein L23 | -0.058235 |
| HMGA1 | high mobility group AT-hook 1 | -0.0568152 |
| RPL34 | ribosomal protein L34 | -0.0554081 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0551606 |
| RPS6 | ribosomal protein S6 | -0.0546967 |
| RPS29 | ribosomal protein S29 | -0.0524188 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.050329 |
| RPL8 | ribosomal protein L8 | -0.0498202 |
| RPS8 | ribosomal protein S8 | -0.0480522 |
| POTEF | POTE ankyrin domain family, member F | -0.046072 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0459105 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.045603 |
| RPS23 | ribosomal protein S23 | -0.044829 |
| RPS27 | ribosomal protein S27 | -0.042473 |
| RPL37A | ribosomal protein L37a | -0.0413922 |
| S100A10 | S100 calcium binding protein A10 | -0.0402936 |
| RPS13 | ribosomal protein S13 | -0.0402935 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0387857 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0382092 |
| RPS14 | ribosomal protein S14 | -0.0377861 |
| B2M | beta-2-microglobulin | -0.0357645 |
| RPS3 | ribosomal protein S3 | -0.0356686 |
| RPL31 | ribosomal protein L31 | -0.033859 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0332138 |
| RPL11 | ribosomal protein L11 | -0.0331439 |
| RPL28 | ribosomal protein L28 | -0.0330515 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0328339 |
| RPL19 | ribosomal protein L19 | -0.0325826 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0324551 |
| RPL36 | ribosomal protein L36 | -0.0318382 |
| HLA-B | major histocompatibility complex, class I, B | -0.0315337 |
| RPL37 | ribosomal protein L37 | -0.0314868 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0309627 |
| RPS25 | ribosomal protein S25 | -0.0309405 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0305824 |
| VIM | vimentin | -0.0302563 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -0.0302102 |
| RPS16 | ribosomal protein S16 | -0.0297573 |
| RPL32 | ribosomal protein L32 | -0.0297103 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0297068 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0290921 |
| RPL12 | ribosomal protein L12 | -0.0289088 |
| RPS11 | ribosomal protein S11 | -0.0282498 |
| HLA-A | major histocompatibility complex, class I, A | -0.0282453 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.027872 |
| RNF145 | ring finger protein 145 | -0.0273374 |
| RPS21 | ribosomal protein S21 | -0.0268796 |
| ENO1 | enolase 1, (alpha) | -0.0268042 |
| RPL9 | ribosomal protein L9 | -0.0267705 |
| RPS12 | ribosomal protein S12 | -0.0266704 |
| FAM162A | family with sequence similarity 162, member A | -0.0266119 |
| RPS27A | ribosomal protein S27a | -0.0266063 |
| RPS10 | ribosomal protein S10 | -0.0259941 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0257168 |
| RPS15 | ribosomal protein S15 | -0.0254015 |
| RPS5 | ribosomal protein S5 | -0.0251209 |
| RPLP0 | ribosomal protein, large, P0 | -0.0250114 |
| ATP5F1E | ATP synthase F1 subunit epsilon | -0.0248576 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0247668 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0246557 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0244873 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0244372 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0244177 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | -0.0243557 |
| AREG | amphiregulin | -0.0241305 |
| RPL5 | ribosomal protein L5 | -0.0240333 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.023938 |
| RPL30 | ribosomal protein L30 | -0.0238064 |
| RPL15 | ribosomal protein L15 | -0.0237476 |
| MUC1 | mucin 1, cell surface associated | -0.0237265 |
| EEF1D | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) | -0.0236115 |
| PKM | pyruvate kinase, muscle | -0.0229597 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0228414 |
| G0S2 | G0/G1 switch 2 | -0.0227193 |
| TXNIP | thioredoxin interacting protein | -0.0226584 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0226399 |
| RBM25 | RNA binding motif protein 25 | -0.0226319 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.0223852 |
| DSTN | destrin (actin depolymerizing factor) | -0.022293 |
| RACK1 | receptor for activated C kinase 1 | -0.0222756 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0220814 |
| CTSD | cathepsin D | -0.0219655 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0214429 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0214167 |
| TPI1 | triosephosphate isomerase 1 | -0.021407 |
| CALR | calreticulin | -0.0210475 |
| RPS17 | ribosomal protein S17 | -0.0208099 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0208024 |
