| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | AZD-8055 perturbation in RPMI-7951 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the AZD-8055_RPMI-7951 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CD44 | CD44 molecule (Indian blood group) | 0.0628113 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.0613108 |
| VEGFA | vascular endothelial growth factor A | 0.050714 |
| MSN | moesin | 0.048477 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.042384 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0417142 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0400492 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0386899 |
| NDRG1 | N-myc downstream regulated 1 | 0.0383452 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0378537 |
| GOLGA4 | golgin A4 | 0.0377812 |
| SMAD3 | SMAD family member 3 | 0.0376505 |
| HDAC9 | histone deacetylase 9 | 0.0367622 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0350986 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0338648 |
| RBM39 | RNA binding motif protein 39 | 0.0325042 |
| ARRDC3 | arrestin domain containing 3 | 0.030958 |
| STC1 | stanniocalcin 1 | 0.030753 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0306271 |
| YEATS2 | YEATS domain containing 2 | 0.0278754 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.027236 |
| SVIL | supervillin | 0.0270424 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0266231 |
| CLIC4 | chloride intracellular channel 4 | 0.0256703 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0246995 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.023802 |
| HSPA8 | heat shock 70kDa protein 8 | 0.023065 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0227122 |
| TMF1 | TATA element modulatory factor 1 | 0.0223465 |
| NCKAP1 | NCK-associated protein 1 | 0.0221781 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0221368 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0217753 |
| ADNP | activity-dependent neuroprotector homeobox | 0.0217642 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.021704 |
| AGPAT5 | 1-acylglycerol-3-phosphate O-acyltransferase 5 | 0.0215817 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0215794 |
| FAT1 | FAT atypical cadherin 1 | 0.02061 |
| RPS2 | ribosomal protein S2 | 0.0204873 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0199458 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0199158 |
| PCBP2 | poly(rC) binding protein 2 | 0.0199141 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0196692 |
| IFI44L | interferon-induced protein 44-like | 0.0195911 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0195687 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0191914 |
| COPA | coatomer protein complex, subunit alpha | 0.0190844 |
| DENND4A | DENN/MADD domain containing 4A | 0.0189566 |
| USP34 | ubiquitin specific peptidase 34 | 0.0186015 |
| OGA | O-GlcNAcase | 0.0185787 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0185207 |
| HELZ | helicase with zinc finger | 0.0184175 |
| PLEC | plectin | 0.0180307 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0179605 |
| GSK3B | glycogen synthase kinase 3 beta | 0.017855 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0178317 |
| ZNF292 | zinc finger protein 292 | 0.0177502 |
| BBX | bobby sox homolog (Drosophila) | 0.0173221 |
| FNIP1 | folliculin interacting protein 1 | 0.0172877 |
| ATOSA | atos homolog A | 0.0171953 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0171559 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0170496 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0170245 |
| CCNL1 | cyclin L1 | 0.0169404 |
| ZNF638 | zinc finger protein 638 | 0.0168335 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.0167849 |
| FAM219A | family with sequence similarity 219, member A | 0.0167587 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0166202 |
| CNBP | CCHC-type zinc finger, nucleic acid binding protein | 0.0165207 |
| ZNF148 | zinc finger protein 148 | 0.0164543 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0164142 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0163534 |
| CSPP1 | centrosome and spindle pole associated protein 1 | 0.0162817 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0162382 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | 0.0162175 |
| ARFGEF1 | ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited) | 0.0160813 |
| CDC73 | cell division cycle 73 | 0.0160523 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0159678 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0159368 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 0.0156435 |
| TFG | TRK-fused gene | 0.0155871 |
| AFDN | afadin, adherens junction formation factor | 0.0155788 |
| EXOC6B | exocyst complex component 6B | 0.0153678 |
| TPM3 | tropomyosin 3 | 0.0153301 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0152961 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0150332 |
| NPTN | neuroplastin | 0.0149888 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.01482 |
| RPL3 | ribosomal protein L3 | 0.0147955 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0147901 |
| CLTC | clathrin, heavy chain (Hc) | 0.0147763 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0147458 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0145434 |
| FMNL2 | formin-like 2 | 0.0145066 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0144574 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0143554 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0143529 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0143436 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0142325 |
| USP24 | ubiquitin specific peptidase 24 | 0.0142047 |
| GOLGB1 | golgin B1 | 0.0141924 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.389804 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.227225 |
| FN1 | fibronectin 1 | -0.196964 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.181875 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.13892 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.136468 |
| HLA-B | major histocompatibility complex, class I, B | -0.123655 |
| COL1A1 | collagen, type I, alpha 1 | -0.103354 |
| CDH13 | cadherin 13 | -0.100649 |
| TMSB10 | thymosin beta 10 | -0.0950257 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0927986 |
| TPM4 | tropomyosin 4 | -0.0892115 |
| FTL | ferritin, light polypeptide | -0.0767856 |
| COL1A2 | collagen, type I, alpha 2 | -0.0697081 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.066111 |
| IER3 | immediate early response 3 | -0.0649097 |
| PTMA | prothymosin, alpha | -0.0606666 |
| INHBA | inhibin, beta A | -0.0582169 |
| B2M | beta-2-microglobulin | -0.0571036 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.054469 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0541962 |
| TNNC1 | troponin C type 1 (slow) | -0.0517988 |
| HLA-A | major histocompatibility complex, class I, A | -0.0502264 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0498078 |
| CALR | calreticulin | -0.0471022 |
| HLA-C | major histocompatibility complex, class I, C | -0.0468741 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0468179 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0466165 |
| ACTG1 | actin gamma 1 | -0.0439301 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0429867 |
| FRMD4A | FERM domain containing 4A | -0.0428633 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0426836 |
| RPL35A | ribosomal protein L35a | -0.0422067 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0419864 |
| APCDD1L | adenomatosis polyposis coli down-regulated 1-like | -0.0410413 |
| IL1B | interleukin 1, beta | -0.040696 |
| MMP12 | matrix metallopeptidase 12 | -0.0401763 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0395392 |
| TPM1 | tropomyosin 1 (alpha) | -0.0394304 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0372131 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0347115 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0343164 |
| RPLP1 | ribosomal protein, large, P1 | -0.0341183 |
| EGR1 | early growth response 1 | -0.033348 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.033316 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.032929 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0321872 |
| CANX | calnexin | -0.0319004 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0293118 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0292207 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | -0.0290875 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0290188 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0289723 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0285368 |
| RPL34 | ribosomal protein L34 | -0.0285266 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0285101 |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) | -0.0284854 |
| ENO1 | enolase 1, (alpha) | -0.0284641 |
| EML5 | echinoderm microtubule associated protein like 5 | -0.0282366 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0278458 |
| RPS8 | ribosomal protein S8 | -0.0273197 |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 | -0.0271322 |
| HM13 | histocompatibility (minor) 13 | -0.026972 |
| RPS24 | ribosomal protein S24 | -0.0264625 |
| GNAS | GNAS complex locus | -0.0262939 |
| VCAN | versican | -0.0249433 |
| PGK1 | phosphoglycerate kinase 1 | -0.0248748 |
| PXDN | peroxidasin | -0.0247096 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0244429 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0239072 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0238459 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0237703 |
| FBXO32 | F-box protein 32 | -0.0236782 |
| FLOT1 | flotillin 1 | -0.0236645 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.023405 |
| COL7A1 | collagen, type VII, alpha 1 | -0.0232542 |
| PLOD1 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 | -0.0232255 |
| FHIT | fragile histidine triad | -0.0229724 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0228086 |
| TNS3 | tensin 3 | -0.0220804 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.021982 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0218673 |
| NAV1 | neuron navigator 1 | -0.0215772 |
| SQSTM1 | sequestosome 1 | -0.0214609 |
| SP100 | SP100 nuclear antigen | -0.0214508 |
| RND3 | Rho family GTPase 3 | -0.0212492 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0211163 |
| SEC61G | Sec61 gamma subunit | -0.0208245 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0207639 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0207288 |
| S100A9 | S100 calcium binding protein A9 | -0.0207043 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0206468 |
| RPL31 | ribosomal protein L31 | -0.0205716 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0203964 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | -0.0203306 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0203 |
| RPS27A | ribosomal protein S27a | -0.0202792 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0201894 |
| RPLP2 | ribosomal protein, large, P2 | -0.020093 |
| S100A6 | S100 calcium binding protein A6 | -0.0200061 |
