| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | AZD-8055 perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the AZD-8055_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.123452 |
| NDRG1 | N-myc downstream regulated 1 | 0.118924 |
| NRXN3 | neurexin 3 | 0.116801 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0949882 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0763072 |
| VEGFA | vascular endothelial growth factor A | 0.0666427 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0654698 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0643404 |
| STC1 | stanniocalcin 1 | 0.0629544 |
| CD44 | CD44 molecule (Indian blood group) | 0.0609019 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0563149 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0554919 |
| GOLGB1 | golgin B1 | 0.0542154 |
| FAM13A | family with sequence similarity 13, member A | 0.0520154 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0508922 |
| CALD1 | caldesmon 1 | 0.048282 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | 0.0479185 |
| EGFR | epidermal growth factor receptor | 0.0465404 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0458886 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0456036 |
| EXOC4 | exocyst complex component 4 | 0.0451248 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0448814 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0447889 |
| ARRDC3 | arrestin domain containing 3 | 0.0447482 |
| CDK6 | cyclin-dependent kinase 6 | 0.0442843 |
| UBC | ubiquitin C | 0.041077 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0403071 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0399038 |
| LOX | lysyl oxidase | 0.0390519 |
| GLIS3 | GLIS family zinc finger 3 | 0.0388915 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0382609 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0380881 |
| AHR | aryl hydrocarbon receptor | 0.0377791 |
| ARHGAP24 | Rho GTPase activating protein 24 | 0.0377749 |
| VEGFC | vascular endothelial growth factor C | 0.0366848 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0364474 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | 0.0356274 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0353097 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0351498 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0351001 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0350422 |
| BBS9 | Bardet-Biedl syndrome 9 | 0.0349964 |
| IL6ST | interleukin 6 signal transducer | 0.0349618 |
| ARB2A | ARB2 cotranscriptional regulator A | 0.0348002 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0347752 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0344864 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.0344029 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0342117 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0328981 |
| MSN | moesin | 0.0327176 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0324387 |
| COG6 | component of oligomeric golgi complex 6 | 0.032304 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0317102 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0314342 |
| APP | amyloid beta (A4) precursor protein | 0.0313228 |
| CA12 | carbonic anhydrase XII | 0.0312383 |
| FNIP1 | folliculin interacting protein 1 | 0.0311963 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0311795 |
| AUTS2 | autism susceptibility candidate 2 | 0.0309251 |
| SMYD3 | SET and MYND domain containing 3 | 0.0308969 |
| ECE1 | endothelin converting enzyme 1 | 0.0299377 |
| SMAD3 | SMAD family member 3 | 0.0296316 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0288492 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0286413 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.028593 |
| RUNX1 | runt-related transcription factor 1 | 0.0284791 |
| IL6 | interleukin 6 | 0.0279447 |
| UTY | ubiquitously transcribed tetratricopeptide repeat containing, Y-linked | 0.027594 |
| ZNF638 | zinc finger protein 638 | 0.0275323 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0274226 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0271889 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0271763 |
| MYADM | myeloid-associated differentiation marker | 0.0271278 |
| EXOC6B | exocyst complex component 6B | 0.0270208 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0268159 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0265841 |
| CYLD | cylindromatosis (turban tumor syndrome) | 0.0265631 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0265508 |
| SETBP1 | SET binding protein 1 | 0.0265316 |
| USP9Y | ubiquitin specific peptidase 9, Y-linked | 0.0262961 |
| SETD5 | SET domain containing 5 | 0.0258012 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0257645 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | 0.0255027 |
| PDXDC1 | pyridoxal-dependent decarboxylase domain containing 1 | 0.0253572 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0252698 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.025217 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0251554 |
| EFNA5 | ephrin-A5 | 0.0250243 |
| SNX13 | sorting nexin 13 | 0.0250068 |
| LNPEP | leucyl/cystinyl aminopeptidase | 0.024964 |
| ANO6 | anoctamin 6 | 0.0247811 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0247609 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0246318 |
| WNT5A | wingless-type MMTV integration site family, member 5A | 0.0244375 |
| PLEC | plectin | 0.024418 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.0241896 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0241419 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0239635 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0238775 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0236605 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.19341 |
| TMSB10 | thymosin beta 10 | -0.160861 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.154864 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.104926 |
| FN1 | fibronectin 1 | -0.095345 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0930441 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0912447 |
| PTMA | prothymosin, alpha | -0.0899218 |
| PRSS23 | protease, serine, 23 | -0.071372 |
| MT2A | metallothionein 2A | -0.0643139 |
| VCL | vinculin | -0.0602533 |
| COL1A2 | collagen, type I, alpha 2 | -0.0525853 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0511749 |
| TPM4 | tropomyosin 4 | -0.0510479 |
| RPL35A | ribosomal protein L35a | -0.0509608 |
| SEPTIN7 | septin 7 | -0.0485716 |
| ACTG1 | actin gamma 1 | -0.0460753 |
| RPLP1 | ribosomal protein, large, P1 | -0.0459866 |
| ENO1 | enolase 1, (alpha) | -0.043658 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0429763 |
| HLA-B | major histocompatibility complex, class I, B | -0.0425521 |
| NAV1 | neuron navigator 1 | -0.0423375 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0418419 |
| RPL34 | ribosomal protein L34 | -0.0416572 |
| HLA-C | major histocompatibility complex, class I, C | -0.0400851 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0383438 |
| FTL | ferritin, light polypeptide | -0.0378232 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0367454 |
| SDC4 | syndecan 4 | -0.0356506 |
| OGA | O-GlcNAcase | -0.0345553 |
| MAP1B | microtubule-associated protein 1B | -0.0343859 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0338875 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0329635 |
| RPL31 | ribosomal protein L31 | -0.0328322 |
| COL1A1 | collagen, type I, alpha 1 | -0.0327528 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0318979 |
| RHEB | Ras homolog enriched in brain | -0.0317262 |
| ANXA2 | annexin A2 | -0.030777 |
| COL7A1 | collagen, type VII, alpha 1 | -0.0302361 |
| TPX2 | TPX2, microtubule-associated | -0.0299595 |
| HMGB2 | high mobility group box 2 | -0.0299148 |
| LMAN1 | lectin, mannose-binding, 1 | -0.02962 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0295575 |
| CST3 | cystatin C | -0.0295256 |
| HLA-A | major histocompatibility complex, class I, A | -0.0292861 |
| RPS16 | ribosomal protein S16 | -0.0291432 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0290075 |
| ARF1 | ADP-ribosylation factor 1 | -0.0272288 |
| OXR1 | oxidation resistance 1 | -0.0267647 |
| GNAS | GNAS complex locus | -0.0263516 |
| TMSB4X | thymosin beta 4, X-linked | -0.0262342 |
| VPS72 | vacuolar protein sorting 72 homolog (S. cerevisiae) | -0.0256984 |
| CAVIN1 | caveolae associated protein 1 | -0.0254974 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | -0.0254804 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0250845 |
| LAMB3 | laminin, beta 3 | -0.0247215 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.024468 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0242718 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0240817 |
| PGK1 | phosphoglycerate kinase 1 | -0.0233295 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0232765 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0232626 |
| TUBA1B | tubulin, alpha 1b | -0.0229743 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0229253 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0227203 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0226817 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0225865 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0225389 |
| CCDC88A | coiled-coil domain containing 88A | -0.0224865 |
| HMGB1 | high mobility group box 1 | -0.0224608 |
| RPS29 | ribosomal protein S29 | -0.0220507 |
| POTEF | POTE ankyrin domain family, member F | -0.0218656 |
| RPL28 | ribosomal protein L28 | -0.0217198 |
| MTPN | myotrophin | -0.0217177 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0216277 |
| RPS12 | ribosomal protein S12 | -0.0215347 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0214762 |
| S100A9 | S100 calcium binding protein A9 | -0.0213494 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.021119 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0209047 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0207994 |
| RPL13A | ribosomal protein L13a | -0.0207392 |
| RPL12 | ribosomal protein L12 | -0.0206789 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0201819 |
| ANLN | anillin, actin binding protein | -0.0201423 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.0200389 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0199809 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0198945 |
| TUBB | tubulin, beta class I | -0.0194285 |
| S100A6 | S100 calcium binding protein A6 | -0.0189653 |
| IGFBP6 | insulin-like growth factor binding protein 6 | -0.0189537 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0184726 |
| RPL38 | ribosomal protein L38 | -0.0183729 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0183599 |
| FAM162A | family with sequence similarity 162, member A | -0.0183405 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0183154 |
| APOLD1 | apolipoprotein L domain containing 1 | -0.0180969 |
| NSD2 | nuclear receptor binding SET domain protein 2 | -0.0180726 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0178796 |
| JMJD1C | jumonji domain containing 1C | -0.0178344 |
