| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | AZD1390 perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the AZD1390_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FMN1 | formin 1 | 0.126515 |
| LSAMP | limbic system-associated membrane protein | 0.116275 |
| VCL | vinculin | 0.106362 |
| NRG1 | neuregulin 1 | 0.103593 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0970673 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0866127 |
| PRKCA | protein kinase C, alpha | 0.0823999 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0646911 |
| ANTXR1 | anthrax toxin receptor 1 | 0.0552191 |
| GREM2 | gremlin 2, DAN family BMP antagonist | 0.0509226 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | 0.0487647 |
| SYT1 | synaptotagmin I | 0.047371 |
| TLE4 | transducin-like enhancer of split 4 | 0.0466008 |
| GLCCI1 | glucocorticoid induced 1 | 0.0418208 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | 0.0410634 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0409052 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.0399591 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0390154 |
| BPTF | bromodomain PHD finger transcription factor | 0.0384016 |
| PLAT | plasminogen activator, tissue | 0.0370808 |
| TPST1 | tyrosylprotein sulfotransferase 1 | 0.0367651 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0346388 |
| ACTG1 | actin gamma 1 | 0.0343854 |
| TPM1 | tropomyosin 1 (alpha) | 0.0341562 |
| COL4A2 | collagen, type IV, alpha 2 | 0.0333427 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | 0.0321859 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.0315513 |
| FRMD4A | FERM domain containing 4A | 0.0315404 |
| COL4A5 | collagen, type IV, alpha 5 | 0.0315284 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | 0.0313643 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0306782 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0305496 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0291796 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | 0.0284234 |
| SIK2 | salt-inducible kinase 2 | 0.0281897 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.0279393 |
| PBX1 | pre-B-cell leukemia homeobox 1 | 0.0277928 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0275267 |
| ANKS1A | ankyrin repeat and sterile alpha motif domain containing 1A | 0.0271781 |
| UNC5C | unc-5 homolog C (C. elegans) | 0.0268926 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | 0.0268241 |
| KLHL13 | kelch-like family member 13 | 0.0267856 |
| VMP1 | vacuole membrane protein 1 | 0.0265118 |
| MAPK10 | mitogen-activated protein kinase 10 | 0.0261998 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | 0.0260798 |
| ST6GALNAC3 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 | 0.0256567 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0254814 |
| PTPRE | protein tyrosine phosphatase, receptor type, E | 0.0253375 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0249775 |
| DNAH14 | dynein, axonemal, heavy chain 14 | 0.0249525 |
| CADM2 | cell adhesion molecule 2 | 0.0248756 |
| PCNX4 | pecanex 4 | 0.0246419 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | 0.024318 |
| AHR | aryl hydrocarbon receptor | 0.0240828 |
| ZNF804A | zinc finger protein 804A | 0.0240525 |
| CNTN4 | contactin 4 | 0.0236072 |
| RAD51B | RAD51 paralog B | 0.0232659 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0229041 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0228534 |
| RNF213 | ring finger protein 213 | 0.0227858 |
| COL4A1 | collagen, type IV, alpha 1 | 0.022396 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0219555 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.0218232 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0217931 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0217065 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0216769 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0216029 |
| CACNB2 | calcium channel, voltage-dependent, beta 2 subunit | 0.021594 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0215315 |
| SIK3 | SIK family kinase 3 | 0.0215254 |
| STK38L | serine/threonine kinase 38 like | 0.0214618 |
| AEBP2 | AE binding protein 2 | 0.0213323 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0211376 |
| NREP | neuronal regeneration related protein | 0.0206237 |
| PRKCE | protein kinase C, epsilon | 0.0206099 |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 | 0.0205658 |
| PDZRN3 | PDZ domain containing ring finger 3 | 0.0205187 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0204741 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0203233 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0201517 |
| ZNF638 | zinc finger protein 638 | 0.0199363 |
| CALD1 | caldesmon 1 | 0.0197468 |
| GPC5 | glypican 5 | 0.0197077 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | 0.0197012 |
| CRH | corticotropin releasing hormone | 0.0196778 |
| SMYD3 | SET and MYND domain containing 3 | 0.0194681 |
| INTS6 | integrator complex subunit 6 | 0.0191921 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | 0.0191546 |
| ARHGAP9 | Rho GTPase activating protein 9 | 0.0191024 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0187549 |
| MSI2 | musashi RNA-binding protein 2 | 0.0187282 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.018709 |
| NCOA7 | nuclear receptor coactivator 7 | 0.0185135 |
| RPL3 | ribosomal protein L3 | 0.0184895 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.0184206 |
| RPTOR | regulatory associated protein of MTOR, complex 1 | 0.0184203 |
| ATM | ATM serine/threonine kinase | 0.0179924 |
| ADAMTS9 | ADAM metallopeptidase with thrombospondin type 1 motif, 9 | 0.0179012 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.0177258 |
| COL18A1 | collagen, type XVIII, alpha 1 | 0.0175686 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | -0.134683 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0915744 |
| IGF2 | insulin-like growth factor 2 | -0.0852315 |
| PTMA | prothymosin, alpha | -0.068434 |
| VIM | vimentin | -0.0660626 |
| WDR45B | WD repeat domain 45B | -0.0446108 |
| RPS6 | ribosomal protein S6 | -0.0426285 |
| FAM13A | family with sequence similarity 13, member A | -0.0421043 |
| NDRG1 | N-myc downstream regulated 1 | -0.0385137 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0370974 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0347628 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0328288 |
| OGA | O-GlcNAcase | -0.0327907 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0313072 |
| HELZ | helicase with zinc finger | -0.0305756 |
| ZNF292 | zinc finger protein 292 | -0.0305422 |
| ANXA2 | annexin A2 | -0.0299751 |
| USP3 | ubiquitin specific peptidase 3 | -0.0285394 |
| LPIN1 | lipin 1 | -0.0283784 |
| S100A6 | S100 calcium binding protein A6 | -0.0278398 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0272317 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0267803 |
| RTN4 | reticulon 4 | -0.026514 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0257792 |
| RPLP0 | ribosomal protein, large, P0 | -0.0251561 |
| GNAS | GNAS complex locus | -0.0251383 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0247821 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0247002 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0244626 |
| RPL34 | ribosomal protein L34 | -0.0241887 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0238813 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0237926 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0235942 |
| TMSB10 | thymosin beta 10 | -0.0232269 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0231364 |
| PHIP | pleckstrin homology domain interacting protein | -0.0231116 |
| CANX | calnexin | -0.0227409 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0213679 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0208167 |
| ASPH | aspartate beta-hydroxylase | -0.0207124 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0207099 |
| GOLGA4 | golgin A4 | -0.0205239 |
| RPL11 | ribosomal protein L11 | -0.0204814 |
| PGK1 | phosphoglycerate kinase 1 | -0.020404 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.020256 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.0202127 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.02008 |
| ENO1 | enolase 1, (alpha) | -0.0198427 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0198416 |
| RPLP1 | ribosomal protein, large, P1 | -0.0197075 |
| RPS24 | ribosomal protein S24 | -0.0195932 |
| HMGB2 | high mobility group box 2 | -0.0195286 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0191842 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0191032 |
| MAP1B | microtubule-associated protein 1B | -0.0190614 |
| RNMT | RNA (guanine-7-) methyltransferase | -0.0186397 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.0186046 |
| RPL38 | ribosomal protein L38 | -0.0182556 |
| RIOK3 | RIO kinase 3 | -0.0178765 |
| SETD5 | SET domain containing 5 | -0.0176532 |
| RPL32 | ribosomal protein L32 | -0.0176264 |
| RNF145 | ring finger protein 145 | -0.0174961 |
| CD36 | CD36 molecule (thrombospondin receptor) | -0.0173731 |
| DENND4C | DENN/MADD domain containing 4C | -0.017308 |
| RPS25 | ribosomal protein S25 | -0.0172441 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0171886 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.016901 |
| UBE2O | ubiquitin-conjugating enzyme E2O | -0.0168586 |
| KIAA1217 | KIAA1217 | -0.0168001 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0167609 |
| FTL | ferritin, light polypeptide | -0.016733 |
| RPL35A | ribosomal protein L35a | -0.0166289 |
| RPS16 | ribosomal protein S16 | -0.0166025 |
| SNX9 | sorting nexin 9 | -0.0165363 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0165195 |
| S100A10 | S100 calcium binding protein A10 | -0.016498 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.016448 |
| RPS19 | ribosomal protein S19 | -0.0164265 |
| UBA2 | ubiquitin-like modifier activating enzyme 2 | -0.0164079 |
| RLF | rearranged L-myc fusion | -0.0161656 |
| HMGA1 | high mobility group AT-hook 1 | -0.0160364 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0159383 |
| FNBP1 | formin binding protein 1 | -0.0158867 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0158198 |
| RAB6A | RAB6A, member RAS oncogene family | -0.015802 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0157833 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.01567 |
| RPL28 | ribosomal protein L28 | -0.0155576 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | -0.0154908 |
| TOB1 | transducer of ERBB2, 1 | -0.0154297 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0153975 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0153814 |
| PPM1D | protein phosphatase, Mg2+/Mn2+ dependent, 1D | -0.0152152 |
| SBF2 | SET binding factor 2 | -0.0151654 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0151041 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.015079 |
| NEK7 | NIMA-related kinase 7 | -0.0149447 |
| RBM39 | RNA binding motif protein 39 | -0.014936 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0148913 |
| S100A9 | S100 calcium binding protein A9 | -0.0148851 |
