| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | AZD1390 perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the AZD1390_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LCN2 | lipocalin 2 | 0.127323 |
| B2M | beta-2-microglobulin | 0.122994 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0776803 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0760631 |
| LYZ | lysozyme | 0.070759 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0654007 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | 0.0537179 |
| ATP11A | ATPase, class VI, type 11A | 0.0474547 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0437187 |
| RUNX1 | runt-related transcription factor 1 | 0.043713 |
| TXNIP | thioredoxin interacting protein | 0.0426631 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.0407802 |
| MUC13 | mucin 13, cell surface associated | 0.0406878 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0383138 |
| MX1 | MX dynamin-like GTPase 1 | 0.0360623 |
| EPHB2 | EPH receptor B2 | 0.0356498 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0351395 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0349472 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0345484 |
| TRIM2 | tripartite motif containing 2 | 0.0339969 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0330658 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0329457 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0312659 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0311608 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0311511 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.0309963 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0305847 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | 0.0298416 |
| ITGA6 | integrin, alpha 6 | 0.029708 |
| FTL | ferritin, light polypeptide | 0.0296933 |
| MX2 | MX dynamin-like GTPase 2 | 0.0296039 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | 0.0294924 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | 0.029491 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0293733 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0267954 |
| FHL2 | four and a half LIM domains 2 | 0.0264908 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0264566 |
| TMC5 | transmembrane channel-like 5 | 0.0264473 |
| SMAD3 | SMAD family member 3 | 0.025329 |
| TTC39B | tetratricopeptide repeat domain 39B | 0.0248877 |
| SPATA13 | spermatogenesis associated 13 | 0.0242539 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | 0.0237202 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0235802 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0233823 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0228993 |
| FNIP2 | folliculin interacting protein 2 | 0.0228046 |
| LY6E | lymphocyte antigen 6 complex, locus E | 0.0220028 |
| TMEM123 | transmembrane protein 123 | 0.0219547 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0217731 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0217411 |
| OARD1 | O-acyl-ADP-ribose deacylase 1 | 0.0212532 |
| IFITM3 | interferon induced transmembrane protein 3 | 0.020739 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0203835 |
| ZNRF3 | zinc and ring finger 3 | 0.0201341 |
| MYO10 | myosin X | 0.0198386 |
| VEGFA | vascular endothelial growth factor A | 0.0198297 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0197367 |
| PTGR1 | prostaglandin reductase 1 | 0.0196849 |
| RNF149 | ring finger protein 149 | 0.0196009 |
| BMP4 | bone morphogenetic protein 4 | 0.0193605 |
| CCNL1 | cyclin L1 | 0.019307 |
| MEIS2 | Meis homeobox 2 | 0.0190483 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0188423 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0187937 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | 0.0186316 |
| LIMA1 | LIM domain and actin binding 1 | 0.0186078 |
| DSTN | destrin (actin depolymerizing factor) | 0.0183775 |
| DNM2 | dynamin 2 | 0.0182924 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0181192 |
| ATP10B | ATPase, class V, type 10B | 0.0180216 |
| MYO1E | myosin IE | 0.0178334 |
| PARP8 | poly (ADP-ribose) polymerase family, member 8 | 0.0177959 |
| OCLN | occludin | 0.0175875 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0174404 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0174117 |
| CST3 | cystatin C | 0.017411 |
| SH3PXD2A | SH3 and PX domains 2A | 0.0172554 |
| PIAS1 | protein inhibitor of activated STAT, 1 | 0.0171924 |
| HLA-A | major histocompatibility complex, class I, A | 0.0171629 |
| FAT1 | FAT atypical cadherin 1 | 0.0171294 |
| RPL21 | ribosomal protein L21 | 0.0169417 |
| STK24 | serine/threonine kinase 24 | 0.0169413 |
| PARP9 | poly (ADP-ribose) polymerase family, member 9 | 0.01684 |
| SEPTIN9 | septin 9 | 0.0168141 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0167101 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0165165 |
| CDC42SE2 | CDC42 small effector 2 | 0.0163851 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0163687 |
| RBCK1 | RanBP-type and C3HC4-type zinc finger containing 1 | 0.0163419 |
| TMEM51 | transmembrane protein 51 | 0.0161534 |
| YAP1 | Yes-associated protein 1 | 0.0160983 |
| SSH2 | slingshot protein phosphatase 2 | 0.0160407 |
| PKM | pyruvate kinase, muscle | 0.0158485 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0158033 |
| TPI1 | triosephosphate isomerase 1 | 0.0154051 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0153605 |
| EHF | ets homologous factor | 0.0152564 |
| TMEM62 | transmembrane protein 62 | 0.0152236 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0151553 |
| SRSF4 | serine/arginine-rich splicing factor 4 | 0.0151386 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TPT1 | tumor protein, translationally-controlled 1 | -0.0968412 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | -0.0940915 |
| ANXA2 | annexin A2 | -0.0797409 |
| LMO7 | LIM domain 7 | -0.0752461 |
| INTS6 | integrator complex subunit 6 | -0.0732292 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.071542 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0528105 |
| SQSTM1 | sequestosome 1 | -0.0476662 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0461653 |
| TM4SF19 | transmembrane 4 L six family member 19 | -0.0458703 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0457633 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | -0.0439115 |
| SDC4 | syndecan 4 | -0.0362406 |
| PLSCR2 | phospholipid scramblase 2 | -0.0358583 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0350862 |
| MUC20 | mucin 20, cell surface associated | -0.0342181 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0335823 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0334198 |
| CANX | calnexin | -0.0297172 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0292581 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0287654 |
| PHF3 | PHD finger protein 3 | -0.0280637 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0279216 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0277042 |
| GOLGB1 | golgin B1 | -0.027655 |
| RAB7A | RAB7A, member RAS oncogene family | -0.026877 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.02484 |
| RPL26 | ribosomal protein L26 | -0.0241507 |
| AHNAK | AHNAK nucleoprotein | -0.0229657 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0228116 |
| NABP1 | nucleic acid binding protein 1 | -0.0217283 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0213378 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0212485 |
| LAMA4 | laminin, alpha 4 | -0.0210407 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0209061 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0207988 |
| LAMB3 | laminin, beta 3 | -0.0205906 |
| EZR | ezrin | -0.020465 |
| JAK1 | Janus kinase 1 | -0.0200825 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0196585 |
| POU2F2 | POU class 2 homeobox 2 | -0.0196441 |
| FNIP1 | folliculin interacting protein 1 | -0.0196298 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0195881 |
| TOP1 | topoisomerase (DNA) I | -0.0195861 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.019465 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0194561 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0194258 |
| POF1B | premature ovarian failure, 1B | -0.0192305 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0187814 |
| RPS8 | ribosomal protein S8 | -0.0186295 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0183098 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0182879 |
| VPS37B | vacuolar protein sorting 37 homolog B (S. cerevisiae) | -0.0177832 |
| HM13 | histocompatibility (minor) 13 | -0.0177101 |
| EFNB2 | ephrin-B2 | -0.0176785 |
| MCU | mitochondrial calcium uniporter | -0.0176443 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.0172938 |
| SPAG9 | sperm associated antigen 9 | -0.0170712 |
| PLEKHM1 | pleckstrin homology domain containing, family M (with RUN domain) member 1 | -0.0169951 |
| RPL7L1 | ribosomal protein L7-like 1 | -0.016956 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0169232 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0169059 |
| MT2A | metallothionein 2A | -0.0168217 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0165626 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0165322 |
| RPS27A | ribosomal protein S27a | -0.016406 |
| RPL37A | ribosomal protein L37a | -0.0163583 |
| HDLBP | high density lipoprotein binding protein | -0.0161183 |
| RPS12 | ribosomal protein S12 | -0.0160187 |
| SCFD1 | sec1 family domain containing 1 | -0.0156821 |
| CAPN8 | calpain 8 | -0.0153779 |
| H1-0 | H1.0 linker histone | -0.0153676 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0152337 |
| NUP98 | nucleoporin 98kDa | -0.0150163 |
| UBAP2 | ubiquitin associated protein 2 | -0.0149877 |
| VMP1 | vacuole membrane protein 1 | -0.0149572 |
| ZNF432 | zinc finger protein 432 | -0.0147275 |
| HKDC1 | hexokinase domain containing 1 | -0.0146969 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0146371 |
| SETX | senataxin | -0.0145508 |
| DOCK5 | dedicator of cytokinesis 5 | -0.014487 |
| RPS24 | ribosomal protein S24 | -0.0144276 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0143891 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.014235 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0141682 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.014122 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0140496 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | -0.0139733 |
| UTRN | utrophin | -0.0138689 |
| ARHGAP27 | Rho GTPase activating protein 27 | -0.0137993 |
| UFM1 | ubiquitin-fold modifier 1 | -0.0137413 |
| RPL34 | ribosomal protein L34 | -0.01371 |
| USP53 | ubiquitin specific peptidase 53 | -0.0135627 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0134341 |
| VIM | vimentin | -0.0133253 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0132438 |
| DSG2 | desmoglein 2 | -0.0132351 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.013215 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.013147 |
| LARP1B | La ribonucleoprotein domain family, member 1B | -0.0130346 |
