| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | AZD1390 perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the AZD1390_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FLNB | filamin B, beta | 0.129241 |
| CD44 | CD44 molecule (Indian blood group) | 0.0774214 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0742717 |
| LMO7 | LIM domain 7 | 0.0676771 |
| AHNAK | AHNAK nucleoprotein | 0.0641163 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0622945 |
| ASPH | aspartate beta-hydroxylase | 0.0620916 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0607434 |
| ENO1 | enolase 1, (alpha) | 0.0607189 |
| UBC | ubiquitin C | 0.0602987 |
| MYOF | myoferlin | 0.0591672 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0575724 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0572457 |
| ITGA6 | integrin, alpha 6 | 0.0555645 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0543387 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.052972 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.0502956 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0499878 |
| FOXO1 | forkhead box O1 | 0.0498468 |
| PLEC | plectin | 0.0475353 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0433969 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0418525 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0404835 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0404146 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0383055 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0377452 |
| NDRG1 | N-myc downstream regulated 1 | 0.0375679 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0368304 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0366194 |
| MTSS1 | metastasis suppressor 1 | 0.0363651 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0361406 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0351017 |
| EMP1 | epithelial membrane protein 1 | 0.0342241 |
| PTK2 | protein tyrosine kinase 2 | 0.0338777 |
| RASAL2 | RAS protein activator like 2 | 0.0338481 |
| NEK7 | NIMA-related kinase 7 | 0.0337082 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.033501 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0329566 |
| TPM3 | tropomyosin 3 | 0.032792 |
| MCL1 | myeloid cell leukemia 1 | 0.0326858 |
| RIN2 | Ras and Rab interactor 2 | 0.0326033 |
| MSN | moesin | 0.0323865 |
| MYO10 | myosin X | 0.0319506 |
| OSMR | oncostatin M receptor | 0.0313866 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0307104 |
| RIGI | RNA sensor RIG-I | 0.0304658 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0293776 |
| DST | dystonin | 0.0293536 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0290228 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0288712 |
| FLNA | filamin A, alpha | 0.0288577 |
| FOXP1 | forkhead box P1 | 0.0281574 |
| JMJD1C | jumonji domain containing 1C | 0.0280762 |
| CALU | calumenin | 0.0280348 |
| PRELID2 | PRELI domain containing 2 | 0.0273574 |
| TGM2 | transglutaminase 2 | 0.0271441 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | 0.0271159 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0270747 |
| FN1 | fibronectin 1 | 0.0269223 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0268449 |
| LNPEP | leucyl/cystinyl aminopeptidase | 0.0261876 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0261874 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0260817 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0259666 |
| ANO6 | anoctamin 6 | 0.0259087 |
| SERINC3 | serine incorporator 3 | 0.0259068 |
| ANXA2 | annexin A2 | 0.0258969 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0257726 |
| NRG1 | neuregulin 1 | 0.0257428 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0252586 |
| MKI67 | marker of proliferation Ki-67 | 0.025205 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0250316 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0248554 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0246277 |
| ACTN4 | actinin, alpha 4 | 0.0246243 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0243618 |
| PODXL | podocalyxin-like | 0.0243117 |
| ATXN1 | ataxin 1 | 0.0242587 |
| PCBP2 | poly(rC) binding protein 2 | 0.0242456 |
| SIK3 | SIK family kinase 3 | 0.0241061 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0241025 |
| CMIP | c-Maf inducing protein | 0.0240465 |
| LDHA | lactate dehydrogenase A | 0.0238865 |
| CLIC4 | chloride intracellular channel 4 | 0.0234484 |
| AMOTL1 | angiomotin like 1 | 0.0233362 |
| SLTM | SAFB-like, transcription modulator | 0.0232061 |
| POTEF | POTE ankyrin domain family, member F | 0.0232034 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0229026 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0228129 |
| EFNA5 | ephrin-A5 | 0.0227793 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0222812 |
| PGK1 | phosphoglycerate kinase 1 | 0.0219207 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0218973 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0217754 |
| SMYD3 | SET and MYND domain containing 3 | 0.0217612 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0217531 |
| CUL4B | cullin 4B | 0.021726 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0216819 |
| DIAPH1 | diaphanous-related formin 1 | 0.0214426 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | 0.0213366 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0916005 |
| RPL11 | ribosomal protein L11 | -0.0433392 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0412129 |
| IGF2 | insulin-like growth factor 2 | -0.0361606 |
| HLA-B | major histocompatibility complex, class I, B | -0.029215 |
| MT2A | metallothionein 2A | -0.0276444 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0266027 |
| FTL | ferritin, light polypeptide | -0.0260266 |
| RPS8 | ribosomal protein S8 | -0.0255585 |
| MEF2A | myocyte enhancer factor 2A | -0.0248596 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0240714 |
| RPL37A | ribosomal protein L37a | -0.0230391 |
| RPL35A | ribosomal protein L35a | -0.0230334 |
| RPLP1 | ribosomal protein, large, P1 | -0.020777 |
| RPS6 | ribosomal protein S6 | -0.0203366 |
| S100A10 | S100 calcium binding protein A10 | -0.0196857 |
| RPS3 | ribosomal protein S3 | -0.0191771 |
| RPL37 | ribosomal protein L37 | -0.0186043 |
| GNAS | GNAS complex locus | -0.0183257 |
| EFHD2 | EF-hand domain family, member D2 | -0.0182619 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | -0.0178638 |
| RPL36 | ribosomal protein L36 | -0.0177042 |
| SQLE | squalene epoxidase | -0.0174079 |
| RPS21 | ribosomal protein S21 | -0.0172451 |
| RPS19 | ribosomal protein S19 | -0.0171314 |
| RPS12 | ribosomal protein S12 | -0.0166163 |
| HMGA1 | high mobility group AT-hook 1 | -0.016157 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0160228 |
| RPS24 | ribosomal protein S24 | -0.0156057 |
| RPL31 | ribosomal protein L31 | -0.0153691 |
| CSTB | cystatin B (stefin B) | -0.0153632 |
| MT1X | metallothionein 1X | -0.0151593 |
| RPS27 | ribosomal protein S27 | -0.0149949 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0145605 |
| RPL9 | ribosomal protein L9 | -0.0143833 |
| GBP2 | guanylate binding protein 2, interferon-inducible | -0.014294 |
| RPL35 | ribosomal protein L35 | -0.0142009 |
| S100A2 | S100 calcium binding protein A2 | -0.0141318 |
| RPLP2 | ribosomal protein, large, P2 | -0.0137784 |
| RPL26 | ribosomal protein L26 | -0.013546 |
| B2M | beta-2-microglobulin | -0.0133794 |
| RPS23 | ribosomal protein S23 | -0.0131777 |
| THBD | thrombomodulin | -0.0130091 |
| RPL34 | ribosomal protein L34 | -0.0127763 |
| NACA | nascent polypeptide-associated complex alpha subunit | -0.0127116 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.0124915 |
| RPL30 | ribosomal protein L30 | -0.0124754 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0124692 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0124259 |
| RAI14 | retinoic acid induced 14 | -0.0123494 |
| RRBP1 | ribosome binding protein 1 | -0.0122009 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0121703 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0121612 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0120376 |
| RPL13A | ribosomal protein L13a | -0.0120252 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0119987 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0119963 |
| RPL28 | ribosomal protein L28 | -0.0118639 |
| RPS25 | ribosomal protein S25 | -0.0117369 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0116028 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0115149 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0114483 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0114117 |
| RPL32 | ribosomal protein L32 | -0.0111102 |
| RPL12 | ribosomal protein L12 | -0.0108332 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0108318 |
| RPL27A | ribosomal protein L27a | -0.0106115 |
| RPL27 | ribosomal protein L27 | -0.0104379 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0104368 |
| MEGF6 | multiple EGF-like-domains 6 | -0.0103855 |
| COX4I1 | cytochrome c oxidase subunit IV isoform 1 | -0.0101413 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | -0.0100877 |
| RPL5 | ribosomal protein L5 | -0.00995906 |
| ADRB2 | adrenoceptor beta 2, surface | -0.00982438 |
| LAMA5 | laminin, alpha 5 | -0.0098192 |
| SYN3 | synapsin III | -0.00977251 |
| H1-0 | H1.0 linker histone | -0.00961952 |
| TMBIM1 | transmembrane BAX inhibitor motif containing 1 | -0.00952673 |
| LRP1B | low density lipoprotein receptor-related protein 1B | -0.00941035 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0092205 |
| HLA-A | major histocompatibility complex, class I, A | -0.00906143 |
| ARFGAP3 | ADP-ribosylation factor GTPase activating protein 3 | -0.00905096 |
| RPL36A | ribosomal protein L36a | -0.00902213 |
| GUK1 | guanylate kinase 1 | -0.00869744 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | -0.0086927 |
| RPS11 | ribosomal protein S11 | -0.00868677 |
| HIBADH | 3-hydroxyisobutyrate dehydrogenase | -0.0086578 |
| CLU | clusterin | -0.00864708 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.00851742 |
| S100A9 | S100 calcium binding protein A9 | -0.00849793 |
| RPS16 | ribosomal protein S16 | -0.00848803 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | -0.00846714 |
| SESTD1 | SEC14 and spectrin domains 1 | -0.00829765 |
| S100A4 | S100 calcium binding protein A4 | -0.00824337 |
| PFN1 | profilin 1 | -0.00804109 |
| RPS6KA5 | ribosomal protein S6 kinase, 90kDa, polypeptide 5 | -0.00801632 |
| TMEM65 | transmembrane protein 65 | -0.00794551 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.00794107 |
| SLMAP | sarcolemma associated protein | -0.0078764 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.00779834 |
