| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | AZD1390 perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the AZD1390_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| RPL3 | ribosomal protein L3 | 0.0537709 |
| TXNRD1 | thioredoxin reductase 1 | 0.0484243 |
| FLNB | filamin B, beta | 0.0424571 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.039092 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0381639 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.037198 |
| PYGB | phosphorylase, glycogen; brain | 0.0314432 |
| SMYD3 | SET and MYND domain containing 3 | 0.0313132 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0281857 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0253707 |
| ZNF292 | zinc finger protein 292 | 0.0248107 |
| DOCK3 | dedicator of cytokinesis 3 | 0.0246541 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0243879 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.0239989 |
| TXNIP | thioredoxin interacting protein | 0.0236626 |
| PLPP3 | phospholipid phosphatase 3 | 0.0234169 |
| PKM | pyruvate kinase, muscle | 0.0233837 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0216584 |
| ZNF608 | zinc finger protein 608 | 0.0205401 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | 0.0203329 |
| AMOTL2 | angiomotin like 2 | 0.0200593 |
| PRELID2 | PRELI domain containing 2 | 0.0199564 |
| PIWIL1 | piwi-like RNA-mediated gene silencing 1 | 0.0197483 |
| YEATS2 | YEATS domain containing 2 | 0.0195616 |
| GSE1 | Gse1 coiled-coil protein | 0.019175 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0185044 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.0180921 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.0180419 |
| EZR | ezrin | 0.0176024 |
| CCNL1 | cyclin L1 | 0.0175338 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0171668 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0169905 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | 0.0168117 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0167521 |
| USP34 | ubiquitin specific peptidase 34 | 0.0166718 |
| ATXN7 | ataxin 7 | 0.0164355 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0163259 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0163111 |
| ZNF638 | zinc finger protein 638 | 0.0161627 |
| HDAC9 | histone deacetylase 9 | 0.0161333 |
| SBF2 | SET binding factor 2 | 0.0160756 |
| FBLN2 | fibulin 2 | 0.0160038 |
| PRDX2 | peroxiredoxin 2 | 0.0159346 |
| RTN4 | reticulon 4 | 0.015927 |
| CD47 | CD47 molecule | 0.0157021 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0156982 |
| NBAS | neuroblastoma amplified sequence | 0.0156911 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0155681 |
| TGFBR3 | transforming growth factor, beta receptor III | 0.0155606 |
| SPRY4 | sprouty homolog 4 (Drosophila) | 0.0155604 |
| MAP3K14 | mitogen-activated protein kinase kinase kinase 14 | 0.0153557 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0150379 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0150079 |
| TBK1 | TANK-binding kinase 1 | 0.0149015 |
| PRRC2A | proline-rich coiled-coil 2A | 0.014713 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0146435 |
| LOXL3 | lysyl oxidase-like 3 | 0.0146353 |
| ARRDC3 | arrestin domain containing 3 | 0.0144224 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0143896 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.0141672 |
| PCBP2 | poly(rC) binding protein 2 | 0.0139973 |
| RNF111 | ring finger protein 111 | 0.0139954 |
| SRPK2 | SRSF protein kinase 2 | 0.0139928 |
| KMT2D | lysine (K)-specific methyltransferase 2D | 0.0139269 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0135876 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | 0.0135664 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0135484 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0134511 |
| SRSF3 | serine/arginine-rich splicing factor 3 | 0.0132773 |
| DOCK1 | dedicator of cytokinesis 1 | 0.013056 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0130212 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0129985 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0129979 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0129212 |
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 | 0.0128552 |
| CEP192 | centrosomal protein 192kDa | 0.0127545 |
| ARFGEF1 | ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited) | 0.0127063 |
| TMEM14B | transmembrane protein 14B | 0.0127005 |
| TNRC6A | trinucleotide repeat containing 6A | 0.0126991 |
| ANK2 | ankyrin 2, neuronal | 0.0126607 |
| CORO1C | coronin, actin binding protein, 1C | 0.0124062 |
| TRIM25 | tripartite motif containing 25 | 0.0122317 |
| SS18 | synovial sarcoma translocation, chromosome 18 | 0.0121889 |
| PLEKHA4 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 | 0.0121801 |
| MSI2 | musashi RNA-binding protein 2 | 0.0121209 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | 0.0120935 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.012075 |
| SYCP2 | synaptonemal complex protein 2 | 0.0120562 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0119831 |
| AHCYL2 | adenosylhomocysteinase-like 2 | 0.0118681 |
| OSMR | oncostatin M receptor | 0.0118244 |
| KRIT1 | KRIT1, ankyrin repeat containing | 0.0117736 |
| MLLT3 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 | 0.0117669 |
| NUP58 | nucleoporin 58 | 0.0116427 |
| PCM1 | pericentriolar material 1 | 0.0115943 |
| NAV2 | neuron navigator 2 | 0.0114944 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0114818 |
| SLC2A13 | solute carrier family 2 (facilitated glucose transporter), member 13 | 0.0114654 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 0.0112388 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0112072 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.279885 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.195468 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.129958 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.129111 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.122244 |
| RPS8 | ribosomal protein S8 | -0.11436 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.111025 |
| RPS6 | ribosomal protein S6 | -0.109556 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.109023 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.108343 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0889318 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0869567 |
| BMP10 | bone morphogenetic protein 10 | -0.0830683 |
| TMSB4X | thymosin beta 4, X-linked | -0.0730542 |
| RPL31 | ribosomal protein L31 | -0.0684855 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0683755 |
| AHNAK | AHNAK nucleoprotein | -0.0668395 |
| VCL | vinculin | -0.0649224 |
| RPL35A | ribosomal protein L35a | -0.063378 |
| CAMKMT | calmodulin-lysine N-methyltransferase | -0.0632948 |
| RPL37A | ribosomal protein L37a | -0.0630905 |
| RPL34 | ribosomal protein L34 | -0.0609739 |
| RPLP1 | ribosomal protein, large, P1 | -0.0607197 |
| RPL12 | ribosomal protein L12 | -0.0604871 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0568089 |
| RPL26 | ribosomal protein L26 | -0.0563932 |
| TNFRSF11B | tumor necrosis factor receptor superfamily, member 11b | -0.0557377 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0537573 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0531937 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0516633 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0504396 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0481586 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0481092 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0480498 |
| EBNA1BP2 | EBNA1 binding protein 2 | -0.0474785 |
| RPLP2 | ribosomal protein, large, P2 | -0.0471187 |
| RPL19 | ribosomal protein L19 | -0.0470207 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0458041 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0454531 |
| RPL7A | ribosomal protein L7a | -0.0433499 |
| ENO1 | enolase 1, (alpha) | -0.0433285 |
| NBEA | neurobeachin | -0.042562 |
| RPS23 | ribosomal protein S23 | -0.0413663 |
| RPS27A | ribosomal protein S27a | -0.0405021 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0399898 |
| RPL37 | ribosomal protein L37 | -0.0381125 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0378681 |
| RPS25 | ribosomal protein S25 | -0.0376752 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0374279 |
| TPM4 | tropomyosin 4 | -0.037255 |
| CANX | calnexin | -0.0365328 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0361709 |
| DIAPH3 | diaphanous-related formin 3 | -0.0360756 |
| PDE7B | phosphodiesterase 7B | -0.0357557 |
| RPS12 | ribosomal protein S12 | -0.0355512 |
| RPL23 | ribosomal protein L23 | -0.0354688 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0348662 |
| RPS24 | ribosomal protein S24 | -0.0340394 |
| RPL9 | ribosomal protein L9 | -0.0337578 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0332883 |
| RPL7 | ribosomal protein L7 | -0.0331728 |
| UNC13A | unc-13 homolog A (C. elegans) | -0.032799 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0326762 |
| S100A4 | S100 calcium binding protein A4 | -0.032047 |
| RPS19 | ribosomal protein S19 | -0.0312097 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0311664 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0310635 |
| GALNT5 | polypeptide N-acetylgalactosaminyltransferase 5 | -0.0303629 |
| MYOF | myoferlin | -0.0302965 |
| ACTG1 | actin gamma 1 | -0.0301746 |
| RACK1 | receptor for activated C kinase 1 | -0.0300336 |
| RPS11 | ribosomal protein S11 | -0.0300282 |
| ANXA1 | annexin A1 | -0.0299527 |
| RPS14 | ribosomal protein S14 | -0.0298948 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0295251 |
| RPL38 | ribosomal protein L38 | -0.0292294 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0289156 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0287616 |
| S100A10 | S100 calcium binding protein A10 | -0.0286654 |
| RPS13 | ribosomal protein S13 | -0.0285562 |
| AEBP2 | AE binding protein 2 | -0.0283098 |
| CACNB4 | calcium channel, voltage-dependent, beta 4 subunit | -0.0281075 |
| RPS29 | ribosomal protein S29 | -0.0280384 |
| RFC3 | replication factor C (activator 1) 3, 38kDa | -0.0275399 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0269008 |
| ANLN | anillin, actin binding protein | -0.0267062 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.026685 |
| EFNA5 | ephrin-A5 | -0.0264258 |
| RPL36A | ribosomal protein L36a | -0.0263518 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0260948 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0257709 |
| PGK1 | phosphoglycerate kinase 1 | -0.0257268 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0255717 |
| CCND1 | cyclin D1 | -0.0254979 |
| RPL35 | ribosomal protein L35 | -0.0254363 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.025122 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0249608 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0249424 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0249205 |
| RPS16 | ribosomal protein S16 | -0.0249083 |
