| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | AZD2858 perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the AZD2858_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VCL | vinculin | 0.19398 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.146744 |
| FMN1 | formin 1 | 0.0937143 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0808137 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0715361 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0596632 |
| TPM4 | tropomyosin 4 | 0.0571672 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0550963 |
| LSAMP | limbic system-associated membrane protein | 0.0536391 |
| NRG1 | neuregulin 1 | 0.0478667 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0460846 |
| EGR1 | early growth response 1 | 0.0444475 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0416438 |
| LIMA1 | LIM domain and actin binding 1 | 0.0412885 |
| SP100 | SP100 nuclear antigen | 0.0403024 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0397648 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0390552 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0390377 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.038954 |
| SLITRK6 | SLIT and NTRK-like family, member 6 | 0.0387448 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0386021 |
| CRH | corticotropin releasing hormone | 0.0384761 |
| RPL31 | ribosomal protein L31 | 0.0380877 |
| LDHA | lactate dehydrogenase A | 0.03788 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0377312 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0373341 |
| TPM1 | tropomyosin 1 (alpha) | 0.0372748 |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 | 0.0363703 |
| MYO1E | myosin IE | 0.0363158 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | 0.0358884 |
| MCL1 | myeloid cell leukemia 1 | 0.0354031 |
| RPL27 | ribosomal protein L27 | 0.0351023 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0348289 |
| GREM2 | gremlin 2, DAN family BMP antagonist | 0.0342269 |
| FERMT2 | fermitin family member 2 | 0.0338258 |
| INTS6 | integrator complex subunit 6 | 0.0330443 |
| RPS12 | ribosomal protein S12 | 0.0329659 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0308977 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.0308533 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0303297 |
| NREP | neuronal regeneration related protein | 0.0294684 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | 0.029263 |
| NDRG1 | N-myc downstream regulated 1 | 0.0289489 |
| RPL23 | ribosomal protein L23 | 0.0286077 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0275933 |
| HOMER1 | homer scaffolding protein 1 | 0.0271476 |
| PALLD | palladin, cytoskeletal associated protein | 0.0269854 |
| SEPTIN9 | septin 9 | 0.026229 |
| CRABP2 | cellular retinoic acid binding protein 2 | 0.0258603 |
| STK38L | serine/threonine kinase 38 like | 0.0252273 |
| RPL37 | ribosomal protein L37 | 0.0250711 |
| COL4A5 | collagen, type IV, alpha 5 | 0.024163 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0236499 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0234261 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0232358 |
| CADM2 | cell adhesion molecule 2 | 0.0232171 |
| RPL7 | ribosomal protein L7 | 0.0230316 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0229635 |
| RPS3 | ribosomal protein S3 | 0.0228344 |
| IER3 | immediate early response 3 | 0.0228318 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.022627 |
| PCBP3 | poly(rC) binding protein 3 | 0.0225309 |
| RPS6 | ribosomal protein S6 | 0.022371 |
| RPL35A | ribosomal protein L35a | 0.0222324 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0221532 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | 0.0220999 |
| FAM107B | family with sequence similarity 107, member B | 0.0219159 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | 0.0218539 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0217121 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.021632 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0214574 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | 0.021073 |
| RPS25 | ribosomal protein S25 | 0.0209829 |
| PLEC | plectin | 0.0209184 |
| FN1 | fibronectin 1 | 0.0207292 |
| SEC24D | SEC24 family member D | 0.0206976 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 | 0.0206685 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0205898 |
| RPL7A | ribosomal protein L7a | 0.019955 |
| GLCCI1 | glucocorticoid induced 1 | 0.0199231 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0197712 |
| ASPH | aspartate beta-hydroxylase | 0.0196028 |
| RACK1 | receptor for activated C kinase 1 | 0.0190031 |
| RGS5 | regulator of G-protein signaling 5 | 0.0189377 |
| HIP1 | huntingtin interacting protein 1 | 0.0189066 |
| KDM2B | lysine (K)-specific demethylase 2B | 0.0186494 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0186235 |
| RPL34 | ribosomal protein L34 | 0.0182328 |
| GPC5 | glypican 5 | 0.0181458 |
| COL4A2 | collagen, type IV, alpha 2 | 0.0180417 |
| CALD1 | caldesmon 1 | 0.0179164 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0177454 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | 0.0177236 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0174902 |
| SYNPO2 | synaptopodin 2 | 0.0173881 |
| RPL36A | ribosomal protein L36a | 0.0173452 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0172903 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0172501 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0171185 |
| GOLGA2 | golgin A2 | 0.017101 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | -0.339781 |
| IGF2 | insulin-like growth factor 2 | -0.271489 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.211415 |
| COL1A1 | collagen, type I, alpha 1 | -0.0600084 |
| MEIS2 | Meis homeobox 2 | -0.058489 |
| LPIN1 | lipin 1 | -0.057278 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0555684 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0535915 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0517487 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0503949 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0455591 |
| MAP1B | microtubule-associated protein 1B | -0.0444253 |
| GATA3 | GATA binding protein 3 | -0.0435622 |
| AOPEP | aminopeptidase O (putative) | -0.0387935 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0387629 |
| FNBP1 | formin binding protein 1 | -0.0384817 |
| ZNF292 | zinc finger protein 292 | -0.0376945 |
| FBXL20 | F-box and leucine-rich repeat protein 20 | -0.0374437 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0374234 |
| GLI3 | GLI family zinc finger 3 | -0.0362361 |
| FOXO3 | forkhead box O3 | -0.0361398 |
| NRP1 | neuropilin 1 | -0.035773 |
| PCBP2 | poly(rC) binding protein 2 | -0.0353919 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0353279 |
| PTMA | prothymosin, alpha | -0.0352585 |
| ZFC3H1 | zinc finger, C3H1-type containing | -0.0349524 |
| JMJD1C | jumonji domain containing 1C | -0.0348326 |
| RBM20 | RNA binding motif protein 20 | -0.0347004 |
| PRRC2C | proline-rich coiled-coil 2C | -0.034013 |
| HAS2 | hyaluronan synthase 2 | -0.0339429 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | -0.033665 |
| UBC | ubiquitin C | -0.0332772 |
| TMSB10 | thymosin beta 10 | -0.0332226 |
| CLTC | clathrin, heavy chain (Hc) | -0.0322215 |
| GLG1 | golgi glycoprotein 1 | -0.0321513 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0311153 |
| MYO6 | myosin VI | -0.0310905 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0307419 |
| SPAG9 | sperm associated antigen 9 | -0.0304815 |
| POTEF | POTE ankyrin domain family, member F | -0.0302965 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0296716 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.02961 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0295942 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | -0.0292318 |
| GOLGA4 | golgin A4 | -0.0292024 |
| HAND2 | heart and neural crest derivatives expressed 2 | -0.0285538 |
| NBAS | neuroblastoma amplified sequence | -0.0281028 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | -0.0280056 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0277843 |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha | -0.0277473 |
| RBM25 | RNA binding motif protein 25 | -0.0273026 |
| RBM39 | RNA binding motif protein 39 | -0.0269863 |
| AHNAK | AHNAK nucleoprotein | -0.0269307 |
| PKM | pyruvate kinase, muscle | -0.0267556 |
| SBF2 | SET binding factor 2 | -0.0266567 |
| SETD5 | SET domain containing 5 | -0.0263812 |
| MYCN | v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog | -0.0261279 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0260342 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.025667 |
| HELZ | helicase with zinc finger | -0.0254894 |
| MATR3 | matrin 3 | -0.025419 |
| RPS27A | ribosomal protein S27a | -0.0252258 |
| CENPF | centromere protein F, 350/400kDa | -0.0252103 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | -0.0252008 |
| KCTD3 | potassium channel tetramerization domain containing 3 | -0.0250865 |
| RPS15 | ribosomal protein S15 | -0.0247224 |
| PHOX2B | paired-like homeobox 2b | -0.0237132 |
| SRPK2 | SRSF protein kinase 2 | -0.0237063 |
| OGA | O-GlcNAcase | -0.023219 |
| TTC17 | tetratricopeptide repeat domain 17 | -0.0230544 |
| ADAR | adenosine deaminase, RNA-specific | -0.0229853 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.0229322 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0228278 |
| RUNX1 | runt-related transcription factor 1 | -0.0227796 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | -0.0224776 |
| CDK19 | cyclin-dependent kinase 19 | -0.022383 |
| MED13L | mediator complex subunit 13-like | -0.0223305 |
| HMGB2 | high mobility group box 2 | -0.0222821 |
| ZC3H15 | zinc finger CCCH-type containing 15 | -0.0222319 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.0222039 |
| DISP1 | dispatched homolog 1 (Drosophila) | -0.0221424 |
| CEP95 | centrosomal protein 95kDa | -0.0220222 |
| KLHL24 | kelch-like family member 24 | -0.0220131 |
| NME2 | NME/NM23 nucleoside diphosphate kinase 2 | -0.02196 |
| TNRC6A | trinucleotide repeat containing 6A | -0.0218627 |
| ARB2A | ARB2 cotranscriptional regulator A | -0.0217701 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0217637 |
| LCOR | ligand dependent nuclear receptor corepressor | -0.0216332 |
| CD36 | CD36 molecule (thrombospondin receptor) | -0.0216331 |
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase | -0.0216021 |
| BBX | bobby sox homolog (Drosophila) | -0.0215702 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | -0.0213614 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0211741 |
| CDC27 | cell division cycle 27 | -0.0208532 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | -0.0208514 |
| TNRC6B | trinucleotide repeat containing 6B | -0.020831 |
| UTY | ubiquitously transcribed tetratricopeptide repeat containing, Y-linked | -0.0208091 |
| CCNG2 | cyclin G2 | -0.0207888 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0207473 |
| WDR45B | WD repeat domain 45B | -0.0207123 |
