| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | AZD2858 perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the AZD2858_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.134227 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.132095 |
| KRT6A | keratin 6A, type II | 0.106479 |
| ENO1 | enolase 1, (alpha) | 0.0805802 |
| LDHA | lactate dehydrogenase A | 0.0648367 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.06469 |
| RPS8 | ribosomal protein S8 | 0.0616778 |
| STC1 | stanniocalcin 1 | 0.0606868 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.058596 |
| PLEC | plectin | 0.0563555 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0517857 |
| CLU | clusterin | 0.0502546 |
| DSTN | destrin (actin depolymerizing factor) | 0.0465483 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.0410462 |
| KRT17 | keratin 17, type I | 0.0406464 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.040408 |
| RPL21 | ribosomal protein L21 | 0.040123 |
| TXNIP | thioredoxin interacting protein | 0.0396693 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0395244 |
| YBX1 | Y box binding protein 1 | 0.0388077 |
| LRP1B | low density lipoprotein receptor-related protein 1B | 0.038587 |
| IFITM1 | interferon induced transmembrane protein 1 | 0.0382791 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0381113 |
| INTS6 | integrator complex subunit 6 | 0.038059 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | 0.0379481 |
| IFITM3 | interferon induced transmembrane protein 3 | 0.0378137 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0366208 |
| FTL | ferritin, light polypeptide | 0.0361326 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0340901 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0335868 |
| LARS1 | leucyl-tRNA synthetase 1 | 0.0330011 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0320829 |
| FRMD6 | FERM domain containing 6 | 0.0310062 |
| MT2A | metallothionein 2A | 0.0308432 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | 0.0301997 |
| RPL32 | ribosomal protein L32 | 0.0296057 |
| NDUFA1 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa | 0.0295025 |
| RPL3 | ribosomal protein L3 | 0.0291947 |
| POTEF | POTE ankyrin domain family, member F | 0.0279991 |
| PDLIM5 | PDZ and LIM domain 5 | 0.027428 |
| HSPA1A | heat shock 70kDa protein 1A | 0.0273422 |
| RACK1 | receptor for activated C kinase 1 | 0.0272655 |
| B2M | beta-2-microglobulin | 0.0272175 |
| TPI1 | triosephosphate isomerase 1 | 0.0272078 |
| RPL35 | ribosomal protein L35 | 0.0271168 |
| ECE1 | endothelin converting enzyme 1 | 0.0270964 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0269329 |
| SON | SON DNA binding protein | 0.0266709 |
| SIK3 | SIK family kinase 3 | 0.0265361 |
| RPL7 | ribosomal protein L7 | 0.0263218 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0260353 |
| UBQLN1 | ubiquilin 1 | 0.0258578 |
| RPL11 | ribosomal protein L11 | 0.0256024 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0255196 |
| ARF1 | ADP-ribosylation factor 1 | 0.0254872 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0251309 |
| RPS14 | ribosomal protein S14 | 0.0249772 |
| SQSTM1 | sequestosome 1 | 0.0249588 |
| DST | dystonin | 0.0245306 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0244903 |
| ASXL1 | additional sex combs like transcriptional regulator 1 | 0.024208 |
| SMAD3 | SMAD family member 3 | 0.0241828 |
| KRT14 | keratin 14, type I | 0.024046 |
| SOX7 | SRY (sex determining region Y)-box 7 | 0.0239886 |
| MYOF | myoferlin | 0.0238196 |
| SEPTIN9 | septin 9 | 0.0236182 |
| RPL5 | ribosomal protein L5 | 0.0234538 |
| PA2G4 | proliferation-associated 2G4, 38kDa | 0.0234469 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0231105 |
| RPS6 | ribosomal protein S6 | 0.022948 |
| TJP1 | tight junction protein 1 | 0.0226768 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0226124 |
| CTNNAL1 | catenin (cadherin-associated protein), alpha-like 1 | 0.0223121 |
| BCR | breakpoint cluster region | 0.0221382 |
| DSPP | dentin sialophosphoprotein | 0.0221359 |
| TPM3 | tropomyosin 3 | 0.0220273 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0219438 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0218643 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0217681 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | 0.0216225 |
| ARRDC3 | arrestin domain containing 3 | 0.0215303 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.021526 |
| SET | SET nuclear proto-oncogene | 0.0213464 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | 0.0208671 |
| RPLP2 | ribosomal protein, large, P2 | 0.020723 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0206638 |
| ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 | 0.0206549 |
| EIF3I | eukaryotic translation initiation factor 3, subunit I | 0.0205901 |
| RPS17 | ribosomal protein S17 | 0.0205576 |
| KRT18 | keratin 18, type I | 0.0203542 |
| TNRC6B | trinucleotide repeat containing 6B | 0.0203471 |
| ANXA1 | annexin A1 | 0.0198849 |
| RPL13A | ribosomal protein L13a | 0.0195915 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.019577 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0190907 |
| BBS9 | Bardet-Biedl syndrome 9 | 0.0190731 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.0190533 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0188574 |
| SERF2 | small EDRK-rich factor 2 | 0.0188502 |
| MAGT1 | magnesium transporter 1 | 0.0187851 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.245618 |
| FLNB | filamin B, beta | -0.156493 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.154844 |
| NDRG1 | N-myc downstream regulated 1 | -0.138188 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.114761 |
| PODXL | podocalyxin-like | -0.10494 |
| SULF1 | sulfatase 1 | -0.0891311 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0844372 |
| PTMA | prothymosin, alpha | -0.0778769 |
| IGF2 | insulin-like growth factor 2 | -0.0758786 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0714912 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0656986 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0646557 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0636126 |
| LAMC2 | laminin, gamma 2 | -0.0607437 |
| MEF2A | myocyte enhancer factor 2A | -0.0586668 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0552301 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0545305 |
| RAI14 | retinoic acid induced 14 | -0.0542577 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0520099 |
| HLA-B | major histocompatibility complex, class I, B | -0.0516277 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.0504107 |
| NAV2 | neuron navigator 2 | -0.0491472 |
| BCL2L1 | BCL2-like 1 | -0.0484234 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0475881 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0469298 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | -0.0462058 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0447575 |
| COL4A5 | collagen, type IV, alpha 5 | -0.0429231 |
| SMYD3 | SET and MYND domain containing 3 | -0.0423417 |
| ANXA2 | annexin A2 | -0.0423049 |
| TNS3 | tensin 3 | -0.0411915 |
| CMIP | c-Maf inducing protein | -0.0406414 |
| ADAMTS16 | ADAM metallopeptidase with thrombospondin type 1 motif, 16 | -0.0402735 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0397173 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0394674 |
| TPM4 | tropomyosin 4 | -0.0388745 |
| LMO7 | LIM domain 7 | -0.0382455 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0379157 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0377358 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0371448 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0369476 |
| GOLGA4 | golgin A4 | -0.0365558 |
| RIGI | RNA sensor RIG-I | -0.0363872 |
| CALB1 | calbindin 1, 28kDa | -0.0360599 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0356647 |
| RBM39 | RNA binding motif protein 39 | -0.0354252 |
| THBD | thrombomodulin | -0.0349618 |
| MECOM | MDS1 and EVI1 complex locus | -0.0345962 |
| LDLR | low density lipoprotein receptor | -0.0345529 |
| CD9 | CD9 molecule | -0.0344625 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0334514 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.033294 |
| PGK1 | phosphoglycerate kinase 1 | -0.0328905 |
| PLS3 | plastin 3 | -0.0327612 |
| ANO1 | anoctamin 1, calcium activated chloride channel | -0.0325891 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0323973 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.030916 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0307858 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0301454 |
| AOPEP | aminopeptidase O (putative) | -0.0299732 |
| MTSS1 | metastasis suppressor 1 | -0.029652 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | -0.0294886 |
| H1-0 | H1.0 linker histone | -0.0294749 |
| OGA | O-GlcNAcase | -0.0294273 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | -0.0294167 |
| HM13 | histocompatibility (minor) 13 | -0.0294057 |
| UTRN | utrophin | -0.0289556 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | -0.0289188 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0286257 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0282798 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | -0.0282794 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0282354 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0279825 |
| COPA | coatomer protein complex, subunit alpha | -0.0278825 |
| ERGIC1 | endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1 | -0.0275888 |
| ACTN4 | actinin, alpha 4 | -0.027042 |
| FNBP4 | formin binding protein 4 | -0.0269646 |
| OSMR | oncostatin M receptor | -0.0268097 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0266112 |
| C4BPB | complement component 4 binding protein, beta | -0.0265537 |
| FOSL1 | FOS-like antigen 1 | -0.0260921 |
| CALU | calumenin | -0.025927 |
| OXR1 | oxidation resistance 1 | -0.0258173 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0257842 |
| NSMCE2 | non-SMC element 2, MMS21 homolog (S. cerevisiae) | -0.0257428 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.0253927 |
| ITGB4 | integrin, beta 4 | -0.0251984 |
| RTN4 | reticulon 4 | -0.0251345 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0245925 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | -0.0245348 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | -0.0244706 |
| SCFD1 | sec1 family domain containing 1 | -0.024282 |
| ATP9A | ATPase, class II, type 9A | -0.0242811 |
| KDM6A | lysine (K)-specific demethylase 6A | -0.0242752 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.024079 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | -0.0240074 |
| COL17A1 | collagen, type XVII, alpha 1 | -0.0239491 |
| DSG2 | desmoglein 2 | -0.0238708 |
| SPAG9 | sperm associated antigen 9 | -0.0236892 |
