| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | AZD2858 perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the AZD2858_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.100874 |
| LDHA | lactate dehydrogenase A | 0.100453 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0973291 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0954847 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0942458 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0831741 |
| PCBP2 | poly(rC) binding protein 2 | 0.0793347 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0760408 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0728998 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0712998 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0698052 |
| LOXL2 | lysyl oxidase-like 2 | 0.0694475 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0687774 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.061275 |
| B2M | beta-2-microglobulin | 0.0610636 |
| FAM20C | family with sequence similarity 20, member C | 0.0595182 |
| AADAC | arylacetamide deacetylase | 0.0592104 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0587011 |
| RPL3 | ribosomal protein L3 | 0.053832 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0528377 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.0465774 |
| SQSTM1 | sequestosome 1 | 0.0464873 |
| SMAD3 | SMAD family member 3 | 0.0462273 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0454341 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0448422 |
| NAV1 | neuron navigator 1 | 0.0444309 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0441111 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 0.0433337 |
| MYO10 | myosin X | 0.0422627 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0419388 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0417624 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0416104 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0412816 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0412335 |
| TGM2 | transglutaminase 2 | 0.0403482 |
| TMSB4X | thymosin beta 4, X-linked | 0.0401544 |
| ENO1 | enolase 1, (alpha) | 0.0401014 |
| PLEC | plectin | 0.0395025 |
| GNGT1 | guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 | 0.0387755 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0376052 |
| GJA1 | gap junction protein, alpha 1, 43kDa | 0.0371987 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0367731 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.03676 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.03533 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0352773 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.035129 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.0349959 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0345669 |
| CA12 | carbonic anhydrase XII | 0.0338994 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0333759 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0330393 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.032607 |
| SEPTIN9 | septin 9 | 0.0317321 |
| NTN4 | netrin 4 | 0.0312546 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0307504 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0303198 |
| OS9 | osteosarcoma amplified 9, endoplasmic reticulum lectin | 0.0302023 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0294475 |
| UBC | ubiquitin C | 0.0294456 |
| PLIN2 | perilipin 2 | 0.0290029 |
| MAP1B | microtubule-associated protein 1B | 0.0289948 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0287026 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0282148 |
| PKM | pyruvate kinase, muscle | 0.0278347 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0278245 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0275368 |
| ASPH | aspartate beta-hydroxylase | 0.0266879 |
| MCL1 | myeloid cell leukemia 1 | 0.0263332 |
| INTS6 | integrator complex subunit 6 | 0.0263068 |
| HSPA8 | heat shock 70kDa protein 8 | 0.025864 |
| CTSC | cathepsin C | 0.0256268 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.0252471 |
| KRT19 | keratin 19, type I | 0.0251454 |
| FAM107B | family with sequence similarity 107, member B | 0.0251217 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0246299 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0245483 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.024223 |
| VEGFA | vascular endothelial growth factor A | 0.0236993 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0235651 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0234821 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0233706 |
| MTR | 5-methyltetrahydrofolate-homocysteine methyltransferase | 0.0227705 |
| IFI44L | interferon-induced protein 44-like | 0.0226546 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0225021 |
| SVIL | supervillin | 0.0224313 |
| GALNT1 | polypeptide N-acetylgalactosaminyltransferase 1 | 0.0220801 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0219846 |
| GPATCH2L | G patch domain containing 2-like | 0.021652 |
| KSR1 | kinase suppressor of ras 1 | 0.0215488 |
| GBP2 | guanylate binding protein 2, interferon-inducible | 0.0213588 |
| HBEGF | heparin-binding EGF-like growth factor | 0.02097 |
| RPLP0 | ribosomal protein, large, P0 | 0.0209118 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.0204396 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0201639 |
| C1QTNF1 | C1q and tumor necrosis factor related protein 1 | 0.0201436 |
| HMGA2 | high mobility group AT-hook 2 | 0.0200798 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0199662 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0197934 |
| PGK1 | phosphoglycerate kinase 1 | 0.0197361 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0195101 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NAMPT | nicotinamide phosphoribosyltransferase | -0.175398 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.139111 |
| TMSB10 | thymosin beta 10 | -0.127112 |
| RBM39 | RNA binding motif protein 39 | -0.0921019 |
| OSMR | oncostatin M receptor | -0.0907008 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0834863 |
| GOLGA4 | golgin A4 | -0.081045 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0807872 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0772023 |
| PTMA | prothymosin, alpha | -0.0722109 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0700954 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0677604 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0668129 |
| USP34 | ubiquitin specific peptidase 34 | -0.0637845 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0631678 |
| MT2A | metallothionein 2A | -0.0631225 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0628453 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0628141 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0618337 |
| GLCCI1 | glucocorticoid induced 1 | -0.0585893 |
| FTL | ferritin, light polypeptide | -0.0583844 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.0575172 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0570895 |
| FN1 | fibronectin 1 | -0.0565448 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0559115 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0529985 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0527134 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0517098 |
| IER3 | immediate early response 3 | -0.0515588 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0513935 |
| ETV6 | ets variant 6 | -0.0510493 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0470105 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0469806 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0457306 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0456549 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | -0.0450814 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0441995 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0434108 |
| JMJD1C | jumonji domain containing 1C | -0.0432108 |
| STC1 | stanniocalcin 1 | -0.042987 |
| PRR16 | proline rich 16 | -0.0429086 |
| NRP1 | neuropilin 1 | -0.041429 |
| MAP4 | microtubule-associated protein 4 | -0.0413873 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0410617 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0406314 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0405249 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0402358 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0401793 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0401186 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0393272 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0391967 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | -0.0389184 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | -0.0388947 |
| H1-0 | H1.0 linker histone | -0.0382232 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0377838 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0376274 |
| TMEM263 | transmembrane protein 263 | -0.0375054 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0372533 |
| RUNX2 | runt-related transcription factor 2 | -0.0371728 |
| FNBP1 | formin binding protein 1 | -0.0370887 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0363661 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0362488 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0361239 |
| OXSR1 | oxidative stress responsive 1 | -0.0359436 |
| EFNA5 | ephrin-A5 | -0.0356691 |
| SETD5 | SET domain containing 5 | -0.0355373 |
| CALR | calreticulin | -0.0350097 |
| GPC6 | glypican 6 | -0.034766 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0347371 |
| FMNL2 | formin-like 2 | -0.0341704 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | -0.0338845 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0336081 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | -0.0333277 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | -0.0331364 |
| DPYSL3 | dihydropyrimidinase-like 3 | -0.0331183 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0328739 |
| ZNF609 | zinc finger protein 609 | -0.0321876 |
| LOX | lysyl oxidase | -0.032029 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.0317614 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0315308 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0314102 |
| ZNF292 | zinc finger protein 292 | -0.0313156 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0309938 |
| USP3 | ubiquitin specific peptidase 3 | -0.0307529 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0307255 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0307042 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0304094 |
| VIM | vimentin | -0.0302891 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.03027 |
| VRK2 | vaccinia related kinase 2 | -0.0301054 |
| PRELID2 | PRELI domain containing 2 | -0.0299746 |
| SBF2 | SET binding factor 2 | -0.0299461 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | -0.0294669 |
| KIAA1328 | KIAA1328 | -0.0294218 |
| DENND4A | DENN/MADD domain containing 4A | -0.0294094 |
| PARD3 | par-3 family cell polarity regulator | -0.0289955 |
| CDC27 | cell division cycle 27 | -0.0289773 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0288681 |
| QKI | QKI, KH domain containing, RNA binding | -0.0288679 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0288131 |
