| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Abemaciclib perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Abemaciclib_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.102213 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0770945 |
| VCL | vinculin | 0.0710501 |
| FAM107B | family with sequence similarity 107, member B | 0.0700981 |
| FMN1 | formin 1 | 0.0689043 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.065074 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.0636804 |
| SEPTIN9 | septin 9 | 0.0634854 |
| TLE4 | transducin-like enhancer of split 4 | 0.0621712 |
| TNFRSF19 | tumor necrosis factor receptor superfamily, member 19 | 0.0576494 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | 0.0572719 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0547923 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0534905 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0530138 |
| PRKCA | protein kinase C, alpha | 0.0522292 |
| DST | dystonin | 0.0520084 |
| MRTFA | myocardin related transcription factor A | 0.0511227 |
| PEAK1 | pseudopodium-enriched atypical kinase 1 | 0.0492265 |
| CLTC | clathrin, heavy chain (Hc) | 0.0483224 |
| KLHL13 | kelch-like family member 13 | 0.046565 |
| DKK2 | dickkopf WNT signaling pathway inhibitor 2 | 0.043619 |
| DNM3 | dynamin 3 | 0.0432968 |
| DACH2 | dachshund family transcription factor 2 | 0.0421285 |
| SIK2 | salt-inducible kinase 2 | 0.042084 |
| FRMD5 | FERM domain containing 5 | 0.041943 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | 0.0411939 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0409859 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0399026 |
| VMP1 | vacuole membrane protein 1 | 0.0398237 |
| MMP16 | matrix metallopeptidase 16 (membrane-inserted) | 0.0396664 |
| PTEN | phosphatase and tensin homolog | 0.0394029 |
| DGKH | diacylglycerol kinase, eta | 0.039154 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0383656 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0381361 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.03697 |
| MAP1B | microtubule-associated protein 1B | 0.0362733 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0357474 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0352161 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0348452 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0339518 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0331656 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0330418 |
| NCAM2 | neural cell adhesion molecule 2 | 0.0327486 |
| GREM2 | gremlin 2, DAN family BMP antagonist | 0.0325388 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0321488 |
| INTS6 | integrator complex subunit 6 | 0.0315419 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0310795 |
| PCBP3 | poly(rC) binding protein 3 | 0.0308187 |
| SEC24D | SEC24 family member D | 0.0302863 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0302064 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0297563 |
| COPA | coatomer protein complex, subunit alpha | 0.0297057 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0292481 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0289836 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | 0.0285741 |
| LARGE1 | LARGE xylosyl- and glucuronyltransferase 1 | 0.0281028 |
| TENM4 | teneurin transmembrane protein 4 | 0.0278143 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.0276688 |
| MED13 | mediator complex subunit 13 | 0.027273 |
| HOMER1 | homer scaffolding protein 1 | 0.0271072 |
| TCF12 | transcription factor 12 | 0.0269258 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | 0.0268976 |
| AOPEP | aminopeptidase O (putative) | 0.0266618 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0266222 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0262745 |
| EPHA4 | EPH receptor A4 | 0.0262626 |
| GOLGA4 | golgin A4 | 0.0261385 |
| LONRF2 | LON peptidase N-terminal domain and ring finger 2 | 0.0258581 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | 0.0256032 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0253582 |
| MALT1 | MALT1 paracaspase | 0.0253383 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0246972 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0246936 |
| CHD9 | chromodomain helicase DNA binding protein 9 | 0.0245848 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0243649 |
| USP36 | ubiquitin specific peptidase 36 | 0.0243506 |
| XPR1 | xenotropic and polytropic retrovirus receptor 1 | 0.0240686 |
| PCDH15 | protocadherin-related 15 | 0.0238635 |
| CAMKMT | calmodulin-lysine N-methyltransferase | 0.0237703 |
| ITGA1 | integrin, alpha 1 | 0.0236423 |
| TRPS1 | trichorhinophalangeal syndrome I | 0.0235842 |
| PTK2 | protein tyrosine kinase 2 | 0.0234188 |
| MEF2A | myocyte enhancer factor 2A | 0.0229844 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0228274 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | 0.0227824 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0225835 |
| SCFD2 | sec1 family domain containing 2 | 0.0225639 |
| AFF3 | AF4/FMR2 family, member 3 | 0.0223995 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0223887 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0218129 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | 0.0216701 |
| FLT1 | fms-related tyrosine kinase 1 | 0.02162 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0215158 |
| UBAP2 | ubiquitin associated protein 2 | 0.0213825 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0213025 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0212148 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0210714 |
| HDLBP | high density lipoprotein binding protein | 0.0210563 |
| SIK3 | SIK family kinase 3 | 0.021049 |
| HECW2 | HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2 | 0.0209805 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGF2 | insulin-like growth factor 2 | -0.235849 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.173879 |
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | -0.137623 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0977653 |
| VIM | vimentin | -0.091031 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0830525 |
| NRG1 | neuregulin 1 | -0.0817288 |
| LSAMP | limbic system-associated membrane protein | -0.0744062 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0607831 |
| NDRG1 | N-myc downstream regulated 1 | -0.0535454 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0486276 |
| RPL23 | ribosomal protein L23 | -0.0471841 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0461004 |
| DPH6 | diphthamine biosynthesis 6 | -0.0458374 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0422566 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0421946 |
| TMSB10 | thymosin beta 10 | -0.0419766 |
| FBXL20 | F-box and leucine-rich repeat protein 20 | -0.0419703 |
| FAM13A | family with sequence similarity 13, member A | -0.041958 |
| RPL35A | ribosomal protein L35a | -0.0414539 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0414042 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.0375848 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0343514 |
| NREP | neuronal regeneration related protein | -0.0340207 |
| RPL38 | ribosomal protein L38 | -0.0339201 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0339199 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0336135 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.033464 |
| RAD51B | RAD51 paralog B | -0.0333939 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0332853 |
| ANTXR1 | anthrax toxin receptor 1 | -0.0325348 |
| CADM2 | cell adhesion molecule 2 | -0.0324408 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | -0.0306376 |
| TNRC6B | trinucleotide repeat containing 6B | -0.0306088 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0305845 |
| PHF3 | PHD finger protein 3 | -0.0296276 |
| RPLP1 | ribosomal protein, large, P1 | -0.0294168 |
| MAPK10 | mitogen-activated protein kinase 10 | -0.0289381 |
| ACTG1 | actin gamma 1 | -0.0289236 |
| FTL | ferritin, light polypeptide | -0.0288585 |
| COL3A1 | collagen, type III, alpha 1 | -0.0286926 |
| CDK19 | cyclin-dependent kinase 19 | -0.0279536 |
| KLHL24 | kelch-like family member 24 | -0.0278215 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.027608 |
| ZNF292 | zinc finger protein 292 | -0.027528 |
| MBTD1 | mbt domain containing 1 | -0.0268371 |
| DIAPH2 | diaphanous-related formin 2 | -0.0255159 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0245649 |
| GPC5 | glypican 5 | -0.0240912 |
| MYCN | v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog | -0.0235759 |
| ST6GALNAC3 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 | -0.0232545 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | -0.0225502 |
| RPS24 | ribosomal protein S24 | -0.0220634 |
| RPS19 | ribosomal protein S19 | -0.0220249 |
| AUH | AU RNA binding protein/enoyl-CoA hydratase | -0.0218513 |
| AUTS2 | autism susceptibility candidate 2 | -0.0216204 |
| RPL34 | ribosomal protein L34 | -0.0215409 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0215397 |
| TFDP2 | transcription factor Dp-2 (E2F dimerization partner 2) | -0.0215215 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0211174 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0210284 |
| PTMA | prothymosin, alpha | -0.0209834 |
| RPS27 | ribosomal protein S27 | -0.020821 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0207887 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0205479 |
| OGA | O-GlcNAcase | -0.020479 |
| RPL32 | ribosomal protein L32 | -0.0203787 |
| KCNIP4 | Kv channel interacting protein 4 | -0.0203709 |
| NEK7 | NIMA-related kinase 7 | -0.0201623 |
| RPL19 | ribosomal protein L19 | -0.0201289 |
| RSF1 | remodeling and spacing factor 1 | -0.0200931 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0200646 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0200459 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.0196777 |
| FRMD4A | FERM domain containing 4A | -0.019638 |
| SCLT1 | sodium channel and clathrin linker 1 | -0.0195892 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.0193753 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0192051 |
| RPS23 | ribosomal protein S23 | -0.0191378 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0190027 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.0187906 |
| FOXN3 | forkhead box N3 | -0.0187733 |
| CENPF | centromere protein F, 350/400kDa | -0.018634 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0180387 |
| AFMID | arylformamidase | -0.0179913 |
| RPL31 | ribosomal protein L31 | -0.0178463 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | -0.0178086 |
| UBXN7 | UBX domain protein 7 | -0.017471 |
| COL1A1 | collagen, type I, alpha 1 | -0.017442 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | -0.0171336 |
| RPL7 | ribosomal protein L7 | -0.0170804 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.017008 |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) | -0.0168624 |
| CLNS1A | chloride channel, nucleotide-sensitive, 1A | -0.016745 |
| ATM | ATM serine/threonine kinase | -0.0167407 |
| XRN1 | 5'-3' exoribonuclease 1 | -0.0166892 |
| TBX2 | T-box 2 | -0.0166757 |
| CD36 | CD36 molecule (thrombospondin receptor) | -0.0166367 |
| NME2 | NME/NM23 nucleoside diphosphate kinase 2 | -0.0166119 |
| SLC6A15 | solute carrier family 6 (neutral amino acid transporter), member 15 | -0.016549 |
