| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Abemaciclib perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Abemaciclib_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| INTS6 | integrator complex subunit 6 | 0.147945 |
| LMO7 | LIM domain 7 | 0.133717 |
| EXT1 | exostosin glycosyltransferase 1 | 0.118806 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | 0.10945 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0920188 |
| HKDC1 | hexokinase domain containing 1 | 0.0893508 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | 0.086207 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | 0.0857173 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.0776728 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.0721493 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0693358 |
| SMAD3 | SMAD family member 3 | 0.0683424 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | 0.0642986 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0607205 |
| PDZD8 | PDZ domain containing 8 | 0.0574263 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0571629 |
| EFNB2 | ephrin-B2 | 0.0563144 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0520041 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0509439 |
| ASPH | aspartate beta-hydroxylase | 0.0503734 |
| ANXA2 | annexin A2 | 0.0476717 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0467303 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | 0.045892 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0450904 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | 0.0447051 |
| TM4SF19 | transmembrane 4 L six family member 19 | 0.0441849 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0432342 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0427418 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0424721 |
| TOP1 | topoisomerase (DNA) I | 0.0418143 |
| NABP1 | nucleic acid binding protein 1 | 0.0410017 |
| ANKRD10 | ankyrin repeat domain 10 | 0.0408361 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0406789 |
| MAP7 | microtubule-associated protein 7 | 0.0399134 |
| DST | dystonin | 0.0390933 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0386255 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0369876 |
| ELOF1 | elongation factor 1 homolog (S. cerevisiae) | 0.0366286 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0364987 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0361424 |
| PMM2 | phosphomannomutase 2 | 0.0354099 |
| DUSP10 | dual specificity phosphatase 10 | 0.035304 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | 0.0352304 |
| DIP2B | DIP2 disco-interacting protein 2 homolog B (Drosophila) | 0.0350929 |
| RAB10 | RAB10, member RAS oncogene family | 0.0346566 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | 0.0339938 |
| RNF213 | ring finger protein 213 | 0.033885 |
| SIPA1L2 | signal-induced proliferation-associated 1 like 2 | 0.0337828 |
| KYNU | kynureninase | 0.033763 |
| RIGI | RNA sensor RIG-I | 0.0325759 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.030942 |
| ARHGEF38 | Rho guanine nucleotide exchange factor (GEF) 38 | 0.0306594 |
| PLEKHM1 | pleckstrin homology domain containing, family M (with RUN domain) member 1 | 0.0299656 |
| PADI1 | peptidyl arginine deiminase, type I | 0.0298087 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0296814 |
| MX1 | MX dynamin-like GTPase 1 | 0.0295574 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0294731 |
| VMP1 | vacuole membrane protein 1 | 0.0293833 |
| SEC24D | SEC24 family member D | 0.0292485 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0291487 |
| RFFL | ring finger and FYVE-like domain containing E3 ubiquitin protein ligase | 0.0288895 |
| GOLGA4 | golgin A4 | 0.0287705 |
| HM13 | histocompatibility (minor) 13 | 0.0285407 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0281343 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) | 0.0277849 |
| HOMER1 | homer scaffolding protein 1 | 0.0276298 |
| TNNC1 | troponin C type 1 (slow) | 0.0276043 |
| UBAP2 | ubiquitin associated protein 2 | 0.0274067 |
| ZNF292 | zinc finger protein 292 | 0.0273667 |
| TMC5 | transmembrane channel-like 5 | 0.0271801 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | 0.0271547 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0266493 |
| JAK1 | Janus kinase 1 | 0.0266212 |
| KIAA1217 | KIAA1217 | 0.0265573 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0264179 |
| COG3 | component of oligomeric golgi complex 3 | 0.0258547 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.0257224 |
| FNIP1 | folliculin interacting protein 1 | 0.0254836 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0254672 |
| PLSCR2 | phospholipid scramblase 2 | 0.0253139 |
| FHIT | fragile histidine triad | 0.0252625 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0249691 |
| TPP2 | tripeptidyl peptidase II | 0.0248811 |
| UCHL3 | ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase) | 0.0244714 |
| LAMA4 | laminin, alpha 4 | 0.0244692 |
| LURAP1L | leucine rich adaptor protein 1-like | 0.0238325 |
| ZBTB43 | zinc finger and BTB domain containing 43 | 0.0238116 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0235604 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0234096 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0232393 |
| YAP1 | Yes-associated protein 1 | 0.0231712 |
| SDC4 | syndecan 4 | 0.0229868 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0228578 |
| ACSL5 | acyl-CoA synthetase long-chain family member 5 | 0.0228464 |
| SEC24A | SEC24 family member A | 0.0227718 |
| NSMCE2 | non-SMC element 2, MMS21 homolog (S. cerevisiae) | 0.0225594 |
| GOLGB1 | golgin B1 | 0.0224551 |
| DIAPH1 | diaphanous-related formin 1 | 0.0222833 |
| SETX | senataxin | 0.0222463 |
| POF1B | premature ovarian failure, 1B | 0.0213407 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.172067 |
| B2M | beta-2-microglobulin | -0.162142 |
| PTMA | prothymosin, alpha | -0.112595 |
| NDRG1 | N-myc downstream regulated 1 | -0.107532 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.10215 |
| TXNIP | thioredoxin interacting protein | -0.0665967 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0661671 |
| LCN2 | lipocalin 2 | -0.0660264 |
| EZR | ezrin | -0.0643556 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0625957 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.0607487 |
| HLA-B | major histocompatibility complex, class I, B | -0.0594303 |
| PERP | PERP, TP53 apoptosis effector | -0.0566698 |
| LYZ | lysozyme | -0.0564441 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0562823 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0527465 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0525514 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0491454 |
| TSC22D1 | TSC22 domain family, member 1 | -0.0471679 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | -0.0461826 |
| RPL35A | ribosomal protein L35a | -0.0453005 |
| RNF149 | ring finger protein 149 | -0.0449439 |
| PGK1 | phosphoglycerate kinase 1 | -0.0443905 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0437324 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0435125 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0433788 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0426042 |
| HLA-E | major histocompatibility complex, class I, E | -0.0425626 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0422798 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | -0.0419297 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0417762 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0404927 |
| H1-0 | H1.0 linker histone | -0.0389238 |
| MT2A | metallothionein 2A | -0.0387301 |
| MEIS2 | Meis homeobox 2 | -0.038278 |
| PHF3 | PHD finger protein 3 | -0.0382085 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0371561 |
| DSPP | dentin sialophosphoprotein | -0.0370932 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0366496 |
| S100A6 | S100 calcium binding protein A6 | -0.0361479 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0350256 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0349811 |
| CD46 | CD46 molecule, complement regulatory protein | -0.0344878 |
| WDR45B | WD repeat domain 45B | -0.0342629 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0338496 |
| HLA-A | major histocompatibility complex, class I, A | -0.0338195 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | -0.0336358 |
| CCNL1 | cyclin L1 | -0.0335531 |
| BICRAL | BICRA like chromatin remodeling complex associated protein | -0.0335104 |
| NBR1 | neighbor of BRCA1 gene 1 | -0.0332806 |
| TMSB10 | thymosin beta 10 | -0.0331122 |
| KLHL24 | kelch-like family member 24 | -0.0329041 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0329032 |
| MPHOSPH8 | M-phase phosphoprotein 8 | -0.0328781 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0328615 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0327036 |
| DIAPH3 | diaphanous-related formin 3 | -0.0325115 |
| ANXA4 | annexin A4 | -0.0315565 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0315207 |
| SMC4 | structural maintenance of chromosomes 4 | -0.031404 |
| OGA | O-GlcNAcase | -0.0312445 |
| EGR1 | early growth response 1 | -0.0310589 |
| SBF2 | SET binding factor 2 | -0.0309876 |
| ACTG1 | actin gamma 1 | -0.0308659 |
| UBAC2 | UBA domain containing 2 | -0.0307039 |
| HLA-C | major histocompatibility complex, class I, C | -0.0303944 |
| UBC | ubiquitin C | -0.0293968 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0292199 |
| KLF3 | Kruppel-like factor 3 (basic) | -0.0291786 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0289066 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | -0.0288777 |
| MKI67 | marker of proliferation Ki-67 | -0.0288128 |
| VOPP1 | vesicular, overexpressed in cancer, prosurvival protein 1 | -0.0287988 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.028667 |
| S100P | S100 calcium binding protein P | -0.0286413 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0286285 |
| EPCAM | epithelial cell adhesion molecule | -0.0282233 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0281519 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.027967 |
| JUP | junction plakoglobin | -0.0279168 |
| KRT19 | keratin 19, type I | -0.0277924 |
| PKM | pyruvate kinase, muscle | -0.0277305 |
| MUC20 | mucin 20, cell surface associated | -0.02751 |
| MUC13 | mucin 13, cell surface associated | -0.0272389 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | -0.0268697 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.0266718 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0266592 |
| PTEN | phosphatase and tensin homolog | -0.0265063 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0261204 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0260173 |
| ABHD2 | abhydrolase domain containing 2 | -0.0260163 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0259381 |
| RPLP1 | ribosomal protein, large, P1 | -0.025895 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0257364 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0257289 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.025606 |
| TMEM62 | transmembrane protein 62 | -0.0255779 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0254647 |
| ZNF395 | zinc finger protein 395 | -0.0248593 |
| UBE2B | ubiquitin-conjugating enzyme E2B | -0.0248436 |
