| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Abemaciclib perturbation in KATO III cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Abemaciclib_KATO III drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.297164 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.144208 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.134735 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.119771 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.112839 |
| GOLGA4 | golgin A4 | 0.1067 |
| FGFR2 | fibroblast growth factor receptor 2 | 0.0972813 |
| FRMD5 | FERM domain containing 5 | 0.0874898 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0858115 |
| ANXA2 | annexin A2 | 0.0823078 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0761301 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.069833 |
| VMP1 | vacuole membrane protein 1 | 0.0656344 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0623291 |
| PMM2 | phosphomannomutase 2 | 0.0621339 |
| MCU | mitochondrial calcium uniporter | 0.061384 |
| FNIP1 | folliculin interacting protein 1 | 0.0595674 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0595361 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0587787 |
| AREG | amphiregulin | 0.058195 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0569087 |
| HM13 | histocompatibility (minor) 13 | 0.0555375 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0546425 |
| HDAC9 | histone deacetylase 9 | 0.054578 |
| RUNX1 | runt-related transcription factor 1 | 0.0523052 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0510302 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0498358 |
| KLHL29 | kelch-like family member 29 | 0.0497348 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0494016 |
| CMIP | c-Maf inducing protein | 0.0485399 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0473451 |
| CANX | calnexin | 0.0470766 |
| RPS6 | ribosomal protein S6 | 0.0469243 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0459022 |
| CLTC | clathrin, heavy chain (Hc) | 0.044769 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0435165 |
| LMO7 | LIM domain 7 | 0.0432606 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0424844 |
| LCN2 | lipocalin 2 | 0.0416257 |
| MYOF | myoferlin | 0.0402411 |
| PGM3 | phosphoglucomutase 3 | 0.0391094 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0386257 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.038355 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0380568 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0377201 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0376983 |
| PLEC | plectin | 0.0373766 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0368543 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0367112 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0366773 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0366675 |
| INTS6 | integrator complex subunit 6 | 0.0364676 |
| SSR1 | signal sequence receptor, alpha | 0.0363845 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | 0.0363505 |
| C6ORF132 | chromosome 6 open reading frame 132 | 0.0363236 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | 0.0360373 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | 0.0355387 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0350937 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0350789 |
| CDK6 | cyclin-dependent kinase 6 | 0.0349769 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.034733 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0346088 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | 0.0344529 |
| SLMAP | sarcolemma associated protein | 0.03422 |
| GDI2 | GDP dissociation inhibitor 2 | 0.0340858 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0337366 |
| ANXA1 | annexin A1 | 0.0336985 |
| COPA | coatomer protein complex, subunit alpha | 0.0334204 |
| SEC24D | SEC24 family member D | 0.0332919 |
| RAB10 | RAB10, member RAS oncogene family | 0.0329435 |
| VEGFA | vascular endothelial growth factor A | 0.0329373 |
| ARCN1 | archain 1 | 0.0326182 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0325986 |
| ANXA3 | annexin A3 | 0.0325969 |
| CDK13 | cyclin-dependent kinase 13 | 0.0325186 |
| IL1RAP | interleukin 1 receptor accessory protein | 0.0325106 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | 0.0324695 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0323642 |
| CTTN | cortactin | 0.032358 |
| SETD5 | SET domain containing 5 | 0.0319069 |
| MTDH | metadherin | 0.0318497 |
| MED13 | mediator complex subunit 13 | 0.0314293 |
| HKDC1 | hexokinase domain containing 1 | 0.0312347 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0311893 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0311783 |
| PDXDC1 | pyridoxal-dependent decarboxylase domain containing 1 | 0.0310481 |
| TES | testin LIM domain protein | 0.0306823 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.0304301 |
| ENO1 | enolase 1, (alpha) | 0.0301914 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0300394 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0299793 |
| TRAM1 | translocation associated membrane protein 1 | 0.0297167 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.029716 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0296517 |
| EPB41 | erythrocyte membrane protein band 4.1 | 0.0296091 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0295132 |
| DSTN | destrin (actin depolymerizing factor) | 0.0294793 |
| TPM3 | tropomyosin 3 | 0.0291932 |
| SLTM | SAFB-like, transcription modulator | 0.0291613 |
| BRD2 | bromodomain containing 2 | 0.0291158 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.160591 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.101324 |
| NPSR1 | neuropeptide S receptor 1 | -0.0839103 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0703528 |
| RPL35A | ribosomal protein L35a | -0.0600845 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0599821 |
| RPS19 | ribosomal protein S19 | -0.059777 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0576738 |
| S100P | S100 calcium binding protein P | -0.05682 |
| S100A6 | S100 calcium binding protein A6 | -0.0563874 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0559995 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0527436 |
| RPLP1 | ribosomal protein, large, P1 | -0.0518208 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0515148 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0489491 |
| B2M | beta-2-microglobulin | -0.0482908 |
| EZR | ezrin | -0.0433168 |
| GSTP1 | glutathione S-transferase pi 1 | -0.0431476 |
| S100A10 | S100 calcium binding protein A10 | -0.0430169 |
| FDFT1 | farnesyl-diphosphate farnesyltransferase 1 | -0.0425907 |
| NDRG1 | N-myc downstream regulated 1 | -0.0416323 |
| TMEM45B | transmembrane protein 45B | -0.041403 |
| KLHL24 | kelch-like family member 24 | -0.0413523 |
| KRT18 | keratin 18, type I | -0.041061 |
| FTL | ferritin, light polypeptide | -0.0408756 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0391989 |
| INSIG1 | insulin induced gene 1 | -0.0391092 |
| ITGB4 | integrin, beta 4 | -0.0376026 |
| KRT19 | keratin 19, type I | -0.0374787 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.035991 |
| H1-0 | H1.0 linker histone | -0.0344359 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.0329026 |
| PRSS3 | protease, serine, 3 | -0.0328642 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.031232 |
| RPLP2 | ribosomal protein, large, P2 | -0.0308438 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0305857 |
| RPL23 | ribosomal protein L23 | -0.0305047 |
| CLDN4 | claudin 4 | -0.0299038 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0296605 |
| PHIP | pleckstrin homology domain interacting protein | -0.0292843 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0292061 |
| SKAP2 | src kinase associated phosphoprotein 2 | -0.0291911 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | -0.0291311 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.0290785 |
| RPL28 | ribosomal protein L28 | -0.0287995 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.0281183 |
| PHF3 | PHD finger protein 3 | -0.0280274 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0279496 |
| CDK19 | cyclin-dependent kinase 19 | -0.0274002 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0271523 |
| ARHGAP12 | Rho GTPase activating protein 12 | -0.0271362 |
| S100A11 | S100 calcium binding protein A11 | -0.0269471 |
| JUP | junction plakoglobin | -0.0266711 |
| RNF43 | ring finger protein 43 | -0.0264486 |
| RSF1 | remodeling and spacing factor 1 | -0.0264084 |
| FOXP1 | forkhead box P1 | -0.0262663 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0260703 |
| ALDOC | aldolase C, fructose-bisphosphate | -0.0260383 |
| HLA-E | major histocompatibility complex, class I, E | -0.0256514 |
| AUH | AU RNA binding protein/enoyl-CoA hydratase | -0.0256061 |
| RPS21 | ribosomal protein S21 | -0.0255853 |
| TNRC6B | trinucleotide repeat containing 6B | -0.0255087 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0252438 |
| ZNF292 | zinc finger protein 292 | -0.025066 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0249935 |
| SERINC1 | serine incorporator 1 | -0.0248543 |
| HLA-C | major histocompatibility complex, class I, C | -0.0248536 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0247029 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0246215 |
| XRN1 | 5'-3' exoribonuclease 1 | -0.0244229 |
| GPX2 | glutathione peroxidase 2 | -0.02433 |
| ACSS2 | acyl-CoA synthetase short-chain family member 2 | -0.0242742 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0238619 |
| OGA | O-GlcNAcase | -0.0236045 |
| NDUFA4 | NDUFA4, mitochondrial complex associated | -0.0235652 |
| SERINC3 | serine incorporator 3 | -0.0231364 |
| ADD3 | adducin 3 (gamma) | -0.0227166 |
| S100A9 | S100 calcium binding protein A9 | -0.0224795 |
| TRIM31 | tripartite motif containing 31 | -0.0224046 |
| NEK7 | NIMA-related kinase 7 | -0.0223034 |
| TXNIP | thioredoxin interacting protein | -0.0221908 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0220476 |
| NBR1 | neighbor of BRCA1 gene 1 | -0.0220267 |
| EXPH5 | exophilin 5 | -0.0219935 |
| RPS29 | ribosomal protein S29 | -0.0219662 |
| EHBP1 | EH domain binding protein 1 | -0.0218871 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0218345 |
| AHNAK | AHNAK nucleoprotein | -0.0217742 |
| RPL26 | ribosomal protein L26 | -0.0215808 |
| ZBTB7A | zinc finger and BTB domain containing 7A | -0.0213742 |
| EPB41L1 | erythrocyte membrane protein band 4.1-like 1 | -0.0208502 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | -0.0206978 |
| ACACA | acetyl-CoA carboxylase alpha | -0.0205052 |
| FBXL20 | F-box and leucine-rich repeat protein 20 | -0.0202665 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0202428 |
| LIMA1 | LIM domain and actin binding 1 | -0.0202104 |
| AGR3 | anterior gradient 3 | -0.0199247 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0198949 |
| ATXN1 | ataxin 1 | -0.0198192 |
| STAG2 | stromal antigen 2 | -0.0196113 |
