| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Abemaciclib perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Abemaciclib_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| BMP2K | BMP2 inducible kinase | 0.087708 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0543025 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0450385 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0446908 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.040506 |
| CTBP2 | C-terminal binding protein 2 | 0.0404348 |
| SLC7A6 | solute carrier family 7 (amino acid transporter light chain, y+L system), member 6 | 0.0380498 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0376657 |
| CARS1 | cysteinyl-tRNA synthetase 1 | 0.0319128 |
| SRSF1 | serine/arginine-rich splicing factor 1 | 0.029644 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0295519 |
| TULP4 | tubby like protein 4 | 0.0294308 |
| TMEM181 | transmembrane protein 181 | 0.0293393 |
| TASOR2 | transcription activation suppressor family member 2 | 0.0285947 |
| STIP1 | stress-induced phosphoprotein 1 | 0.028511 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0279211 |
| ANXA1 | annexin A1 | 0.0277672 |
| CPNE1 | copine I | 0.0276918 |
| ELOVL5 | ELOVL fatty acid elongase 5 | 0.0272258 |
| VPS50 | VPS50 subunit of EARP/GARPII complex | 0.0272145 |
| CREB3L2 | cAMP responsive element binding protein 3-like 2 | 0.0268643 |
| RIOX2 | ribosomal oxygenase 2 | 0.0258645 |
| ZSCAN5A | zinc finger and SCAN domain containing 5A | 0.0258291 |
| EMP1 | epithelial membrane protein 1 | 0.025738 |
| JADE1 | jade family PHD finger 1 | 0.0253274 |
| TTC23 | tetratricopeptide repeat domain 23 | 0.0252767 |
| EFNA5 | ephrin-A5 | 0.0251816 |
| DNAJC10 | DnaJ (Hsp40) homolog, subfamily C, member 10 | 0.0251354 |
| IFRD1 | interferon-related developmental regulator 1 | 0.0248653 |
| AP2A1 | adaptor-related protein complex 2, alpha 1 subunit | 0.0248528 |
| AKAP7 | A kinase (PRKA) anchor protein 7 | 0.02473 |
| TMCO3 | transmembrane and coiled-coil domains 3 | 0.0246847 |
| IL13RA1 | interleukin 13 receptor, alpha 1 | 0.0244031 |
| TXLNA | taxilin alpha | 0.0242054 |
| FLNB | filamin B, beta | 0.0239743 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0238992 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | 0.0237966 |
| RAB10 | RAB10, member RAS oncogene family | 0.0237376 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0236398 |
| ZMYM1 | zinc finger, MYM-type 1 | 0.0235625 |
| GNG12 | guanine nucleotide binding protein (G protein), gamma 12 | 0.0233376 |
| DST | dystonin | 0.0232613 |
| PDS5B | PDS5 cohesin associated factor B | 0.0232287 |
| PSMF1 | proteasome (prosome, macropain) inhibitor subunit 1 (PI31) | 0.0231306 |
| ARHGEF11 | Rho guanine nucleotide exchange factor (GEF) 11 | 0.0226225 |
| GDI2 | GDP dissociation inhibitor 2 | 0.0225569 |
| CDK8 | cyclin-dependent kinase 8 | 0.0224214 |
| EHMT1 | euchromatic histone-lysine N-methyltransferase 1 | 0.0223076 |
| EIF4E2 | eukaryotic translation initiation factor 4E family member 2 | 0.0221779 |
| HMGA1 | high mobility group AT-hook 1 | 0.0217906 |
| SMARCA2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 | 0.0216865 |
| VIPR1 | vasoactive intestinal peptide receptor 1 | 0.0216821 |
| RNGTT | RNA guanylyltransferase and 5'-phosphatase | 0.0216467 |
| SMG6 | SMG6 nonsense mediated mRNA decay factor | 0.0215843 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0213096 |
| MAPKAP1 | mitogen-activated protein kinase associated protein 1 | 0.0211408 |
| ZSWIM5 | zinc finger, SWIM-type containing 5 | 0.021124 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0209443 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0207208 |
| RPTOR | regulatory associated protein of MTOR, complex 1 | 0.0204508 |
| SLC25A13 | solute carrier family 25 (aspartate/glutamate carrier), member 13 | 0.0203184 |
| NIN | ninein (GSK3B interacting protein) | 0.0199794 |
| STAM2 | signal transducing adaptor molecule (SH3 domain and ITAM motif) 2 | 0.0199773 |
| IST1 | increased sodium tolerance 1 homolog (yeast) | 0.0199447 |
| SPPL3 | signal peptide peptidase like 3 | 0.0197047 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | 0.019592 |
| MAP3K14 | mitogen-activated protein kinase kinase kinase 14 | 0.0195214 |
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | 0.0192736 |
| SCFD2 | sec1 family domain containing 2 | 0.0192722 |
| EXOC2 | exocyst complex component 2 | 0.0192118 |
| NKTR | natural killer cell triggering receptor | 0.0191652 |
| TRIM5 | tripartite motif containing 5 | 0.0190765 |
| NAP1L4 | nucleosome assembly protein 1-like 4 | 0.0190682 |
| TRIM25 | tripartite motif containing 25 | 0.0190056 |
| XRN2 | 5'-3' exoribonuclease 2 | 0.0189262 |
| RASAL2 | RAS protein activator like 2 | 0.0188155 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.018397 |
| MIPOL1 | mirror-image polydactyly 1 | 0.0183748 |
| DIAPH1 | diaphanous-related formin 1 | 0.0183687 |
| ERCC6L2 | excision repair cross-complementation group 6-like 2 | 0.0182503 |
| TBK1 | TANK-binding kinase 1 | 0.0181619 |
| GOLM2 | golgi membrane protein 2 | 0.0181422 |
| HM13 | histocompatibility (minor) 13 | 0.0180634 |
| DOCK5 | dedicator of cytokinesis 5 | 0.018057 |
| ARF4 | ADP-ribosylation factor 4 | 0.0180212 |
| ANXA2 | annexin A2 | 0.0180014 |
| S100A11 | S100 calcium binding protein A11 | 0.0178291 |
| TNRC6A | trinucleotide repeat containing 6A | 0.0177132 |
| FOXJ3 | forkhead box J3 | 0.0175389 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0175176 |
| UBE2V1 | ubiquitin-conjugating enzyme E2 variant 1 | 0.0173361 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0173099 |
| USP15 | ubiquitin specific peptidase 15 | 0.016894 |
| UPF3A | UPF3 regulator of nonsense transcripts homolog A (yeast) | 0.0167375 |
| TTC17 | tetratricopeptide repeat domain 17 | 0.0166195 |
| MAP3K13 | mitogen-activated protein kinase kinase kinase 13 | 0.0165997 |
| ZNF608 | zinc finger protein 608 | 0.016447 |
| MARK2 | MAP/microtubule affinity-regulating kinase 2 | 0.0164363 |
| SS18 | synovial sarcoma translocation, chromosome 18 | 0.0164271 |
| IQCJ | IQ motif containing J | 0.0164105 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.160472 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.137042 |
| VCL | vinculin | -0.101877 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.101474 |
| ADAM10 | ADAM metallopeptidase domain 10 | -0.09711 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0926908 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0793071 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.0773385 |
| RPS6 | ribosomal protein S6 | -0.0759687 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0672754 |
| FOXP1 | forkhead box P1 | -0.0639263 |
| LDHA | lactate dehydrogenase A | -0.061038 |
| TXNRD1 | thioredoxin reductase 1 | -0.0595271 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0589097 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0551118 |
| RBM39 | RNA binding motif protein 39 | -0.0546908 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0534813 |
| SOX6 | SRY (sex determining region Y)-box 6 | -0.0528058 |
| RPL11 | ribosomal protein L11 | -0.0518149 |
| TMSB4X | thymosin beta 4, X-linked | -0.0514117 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0506964 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0474073 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0466034 |
| NBEA | neurobeachin | -0.0465115 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.0449054 |
| TJP1 | tight junction protein 1 | -0.0446001 |
| S100A6 | S100 calcium binding protein A6 | -0.0421345 |
| AHNAK | AHNAK nucleoprotein | -0.0420753 |
| RPL35A | ribosomal protein L35a | -0.0414139 |
| PGK1 | phosphoglycerate kinase 1 | -0.0410859 |
| BMP10 | bone morphogenetic protein 10 | -0.0407311 |
| RPL12 | ribosomal protein L12 | -0.0403085 |
| GOLGA4 | golgin A4 | -0.0400409 |
| B2M | beta-2-microglobulin | -0.0399712 |
| RPL31 | ribosomal protein L31 | -0.0399653 |
| NFIA | nuclear factor I/A | -0.0399383 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0389844 |
| RPS12 | ribosomal protein S12 | -0.0386012 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0384995 |
| RPLP1 | ribosomal protein, large, P1 | -0.037352 |
| RPL26 | ribosomal protein L26 | -0.0355422 |
| SMC3 | structural maintenance of chromosomes 3 | -0.0354179 |
| ENO1 | enolase 1, (alpha) | -0.0352518 |
| PKM | pyruvate kinase, muscle | -0.0352479 |
| RPS23 | ribosomal protein S23 | -0.0349548 |
| RPLP0 | ribosomal protein, large, P0 | -0.0348184 |
| RPS19 | ribosomal protein S19 | -0.0344303 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.033552 |
| RPS13 | ribosomal protein S13 | -0.0330615 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0330158 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0328308 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.032666 |
| GCNT1 | glucosaminyl (N-acetyl) transferase 1, core 2 | -0.0325111 |
| EVI5 | ecotropic viral integration site 5 | -0.0323781 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0323088 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.0322617 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0322177 |
| CACNB4 | calcium channel, voltage-dependent, beta 4 subunit | -0.0317222 |
| SQSTM1 | sequestosome 1 | -0.0314799 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0305143 |
| PFN1 | profilin 1 | -0.0302378 |
| DUSP4 | dual specificity phosphatase 4 | -0.0296841 |
| CENPF | centromere protein F, 350/400kDa | -0.0293418 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0291543 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0289715 |
| ACTG1 | actin gamma 1 | -0.0286108 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.028532 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0275913 |
| POTEF | POTE ankyrin domain family, member F | -0.0275725 |
| ECT2 | epithelial cell transforming 2 | -0.0275566 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0272795 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0271833 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0267826 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0266225 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0266194 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0265628 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0264766 |
| RPL7A | ribosomal protein L7a | -0.0264121 |
| RPS3 | ribosomal protein S3 | -0.0262475 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0257253 |
| CD47 | CD47 molecule | -0.0255959 |
| SET | SET nuclear proto-oncogene | -0.0254501 |
| RPL37A | ribosomal protein L37a | -0.0251935 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0249708 |
| RPL27A | ribosomal protein L27a | -0.0249053 |
| RPS25 | ribosomal protein S25 | -0.0248617 |
| CANX | calnexin | -0.0243779 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.0243647 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0242414 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0241912 |
| RPLP2 | ribosomal protein, large, P2 | -0.0239948 |
| SEPTIN7 | septin 7 | -0.0239612 |
| TRERF1 | transcriptional regulating factor 1 | -0.0237847 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.023724 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.0231978 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0231776 |
| TNRC6B | trinucleotide repeat containing 6B | -0.023162 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0229276 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0228985 |
| RPL36 | ribosomal protein L36 | -0.0228934 |
