| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Abiraterone acetate perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Abiraterone acetate_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.170284 |
| NDRG1 | N-myc downstream regulated 1 | 0.0861752 |
| MT2A | metallothionein 2A | 0.0708705 |
| TMSB10 | thymosin beta 10 | 0.0634567 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0619689 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0609908 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0510707 |
| B2M | beta-2-microglobulin | 0.0489353 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0479945 |
| S100A6 | S100 calcium binding protein A6 | 0.042966 |
| CSTB | cystatin B (stefin B) | 0.0419691 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0400984 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0371264 |
| VIM | vimentin | 0.0353798 |
| FTL | ferritin, light polypeptide | 0.0346413 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0337184 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0328765 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0315813 |
| L1CAM | L1 cell adhesion molecule | 0.028608 |
| LMNA | lamin A/C | 0.0271564 |
| FOSL1 | FOS-like antigen 1 | 0.0257744 |
| ADM | adrenomedullin | 0.0251154 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0246953 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.024606 |
| OPTN | optineurin | 0.0244222 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0240241 |
| PIEZO1 | piezo-type mechanosensitive ion channel component 1 | 0.0239191 |
| POTEF | POTE ankyrin domain family, member F | 0.0233768 |
| MNT | MAX network transcriptional repressor | 0.0232356 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0231006 |
| RPL36 | ribosomal protein L36 | 0.022678 |
| COPA | coatomer protein complex, subunit alpha | 0.0225179 |
| AP2M1 | adaptor-related protein complex 2, mu 1 subunit | 0.0221337 |
| PLEC | plectin | 0.022076 |
| VEGFA | vascular endothelial growth factor A | 0.0216993 |
| FLNA | filamin A, alpha | 0.0212546 |
| CD109 | CD109 molecule | 0.0208316 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0206523 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | 0.020466 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | 0.0195397 |
| GOLGA2 | golgin A2 | 0.0194049 |
| FAM107B | family with sequence similarity 107, member B | 0.0192021 |
| MYADM | myeloid-associated differentiation marker | 0.019071 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0190495 |
| HLA-A | major histocompatibility complex, class I, A | 0.0190037 |
| PFN1 | profilin 1 | 0.0188789 |
| MSN | moesin | 0.0187884 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0185561 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0183706 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0182521 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0179974 |
| INSIG2 | insulin induced gene 2 | 0.0179533 |
| LAMA5 | laminin, alpha 5 | 0.0174833 |
| TAGLN2 | transgelin 2 | 0.0172761 |
| SH3GL1 | SH3-domain GRB2-like 1 | 0.0170458 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | 0.0170111 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0168182 |
| RBCK1 | RanBP-type and C3HC4-type zinc finger containing 1 | 0.0165738 |
| CSPG4 | chondroitin sulfate proteoglycan 4 | 0.0164867 |
| GADD45B | growth arrest and DNA-damage-inducible, beta | 0.0164533 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0162083 |
| RTN4 | reticulon 4 | 0.0160444 |
| RAB18 | RAB18, member RAS oncogene family | 0.0159651 |
| RAB6A | RAB6A, member RAS oncogene family | 0.015917 |
| AXL | AXL receptor tyrosine kinase | 0.0158398 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | 0.0157632 |
| C1D | C1D nuclear receptor corepressor | 0.0155511 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0155394 |
| CYTH3 | cytohesin 3 | 0.0152875 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0151695 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.014949 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0149363 |
| IFITM3 | interferon induced transmembrane protein 3 | 0.0148668 |
| PCMT1 | protein-L-isoaspartate (D-aspartate) O-methyltransferase | 0.0147465 |
| TGFB1 | transforming growth factor, beta 1 | 0.0147322 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.0147297 |
| SEC61G | Sec61 gamma subunit | 0.0146539 |
| ULK1 | unc-51 like autophagy activating kinase 1 | 0.0146309 |
| CTBP2 | C-terminal binding protein 2 | 0.0145935 |
| CALR | calreticulin | 0.0145743 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.0145711 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0143307 |
| MEF2D | myocyte enhancer factor 2D | 0.014138 |
| IL32 | interleukin 32 | 0.0140929 |
| MRPS6 | mitochondrial ribosomal protein S6 | 0.0138958 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0138001 |
| RPS19 | ribosomal protein S19 | 0.0136452 |
| PCBP2 | poly(rC) binding protein 2 | 0.0135024 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0134211 |
| TNNT1 | troponin T type 1 (skeletal, slow) | 0.0134117 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0133789 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0133721 |
| PGM3 | phosphoglucomutase 3 | 0.0133414 |
| RNMT | RNA (guanine-7-) methyltransferase | 0.0132843 |
| PLXNA3 | plexin A3 | 0.013183 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0130842 |
| LPCAT2 | lysophosphatidylcholine acyltransferase 2 | 0.0129724 |
| RACK1 | receptor for activated C kinase 1 | 0.0129363 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | 0.0129245 |
| RPS3 | ribosomal protein S3 | 0.0127573 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.23132 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.176845 |
| COL3A1 | collagen, type III, alpha 1 | -0.117644 |
| AHNAK | AHNAK nucleoprotein | -0.104551 |
| CD44 | CD44 molecule (Indian blood group) | -0.0830838 |
| COL1A2 | collagen, type I, alpha 2 | -0.0830235 |
| FBN1 | fibrillin 1 | -0.0819937 |
| THBS2 | thrombospondin 2 | -0.0814981 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0782171 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0707472 |
| NAV1 | neuron navigator 1 | -0.0688542 |
| LOX | lysyl oxidase | -0.0643772 |
| MX2 | MX dynamin-like GTPase 2 | -0.063392 |
| RIGI | RNA sensor RIG-I | -0.0621915 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0604349 |
| MAP1B | microtubule-associated protein 1B | -0.0594768 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0586932 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.058378 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0561339 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0533517 |
| COL5A2 | collagen, type V, alpha 2 | -0.0512349 |
| CANX | calnexin | -0.0501905 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0486919 |
| TMSB4X | thymosin beta 4, X-linked | -0.0473272 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0465984 |
| PLAT | plasminogen activator, tissue | -0.0460572 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0454441 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0443676 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.044101 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0437288 |
| APP | amyloid beta (A4) precursor protein | -0.0426866 |
| FSTL1 | follistatin-like 1 | -0.0414689 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | -0.0413065 |
| GPC6 | glypican 6 | -0.0405266 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0397944 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0387885 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0384271 |
| ZNF217 | zinc finger protein 217 | -0.0381097 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0369982 |
| SMYD3 | SET and MYND domain containing 3 | -0.03686 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0362233 |
| CDK6 | cyclin-dependent kinase 6 | -0.0360851 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0357358 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0348228 |
| MEIS2 | Meis homeobox 2 | -0.0347736 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0345555 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0338033 |
| PRELID2 | PRELI domain containing 2 | -0.0330279 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0326666 |
| NF1 | neurofibromin 1 | -0.0325044 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0324351 |
| SBF2 | SET binding factor 2 | -0.0316877 |
| SAMD9L | sterile alpha motif domain containing 9-like | -0.0314964 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0308312 |
| HS3ST3A1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 | -0.0307243 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0307232 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0305827 |
| ASPH | aspartate beta-hydroxylase | -0.0305049 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0297279 |
| GLIS3 | GLIS family zinc finger 3 | -0.0294792 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0293829 |
| EFNA5 | ephrin-A5 | -0.0292481 |
| S100A10 | S100 calcium binding protein A10 | -0.0289904 |
| GLG1 | golgi glycoprotein 1 | -0.0289304 |
| ANO6 | anoctamin 6 | -0.0286922 |
| RRBP1 | ribosome binding protein 1 | -0.0286735 |
| OSMR | oncostatin M receptor | -0.0285154 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0284853 |
| RAI14 | retinoic acid induced 14 | -0.0284259 |
| DPYSL3 | dihydropyrimidinase-like 3 | -0.0284106 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0282873 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0281283 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0280051 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0278003 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0274999 |
| EHBP1 | EH domain binding protein 1 | -0.0267126 |
| FUS | FUS RNA binding protein | -0.0266271 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0266137 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.026489 |
| CUX1 | cut-like homeobox 1 | -0.0263829 |
| MAP4 | microtubule-associated protein 4 | -0.0263428 |
| USP34 | ubiquitin specific peptidase 34 | -0.0262424 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.0261802 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0258713 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0258527 |
| CAVIN1 | caveolae associated protein 1 | -0.025847 |
| DST | dystonin | -0.025803 |
| PRSS23 | protease, serine, 23 | -0.0256529 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0252203 |
| FRMD4A | FERM domain containing 4A | -0.0246732 |
| RRM2 | ribonucleotide reductase M2 | -0.0242456 |
| ATP13A3 | ATPase type 13A3 | -0.0240655 |
| RUNX1 | runt-related transcription factor 1 | -0.0240104 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0238855 |
| CCND1 | cyclin D1 | -0.0238093 |
| PODXL | podocalyxin-like | -0.0237021 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0236891 |
| RPS24 | ribosomal protein S24 | -0.0236449 |
| TENM3 | teneurin transmembrane protein 3 | -0.0234612 |
| ARF1 | ADP-ribosylation factor 1 | -0.0234224 |
