| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Abiraterone acetate perturbation in A-427 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Abiraterone acetate_A-427 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NLGN1 | neuroligin 1 | 0.158769 |
| HMGA2 | high mobility group AT-hook 2 | 0.10188 |
| YAP1 | Yes-associated protein 1 | 0.0960997 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0853434 |
| RRM2 | ribonucleotide reductase M2 | 0.0722069 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0658838 |
| NHSL1 | NHS-like 1 | 0.064395 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0583563 |
| EGR1 | early growth response 1 | 0.0545834 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.052121 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0496477 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0486349 |
| INTS6 | integrator complex subunit 6 | 0.0486125 |
| ASPH | aspartate beta-hydroxylase | 0.0474682 |
| WWOX | WW domain containing oxidoreductase | 0.0467174 |
| JMJD1C | jumonji domain containing 1C | 0.0454768 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.042473 |
| TPM3 | tropomyosin 3 | 0.0416866 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.041633 |
| PCDH9 | protocadherin 9 | 0.0399949 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.037788 |
| PDGFC | platelet derived growth factor C | 0.0353542 |
| EPHA5 | EPH receptor A5 | 0.0352989 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0342965 |
| CDH12 | cadherin 12, type 2 (N-cadherin 2) | 0.0338221 |
| DENND5A | DENN/MADD domain containing 5A | 0.0322974 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | 0.0319836 |
| NEGR1 | neuronal growth regulator 1 | 0.0307571 |
| RTN4 | reticulon 4 | 0.0306548 |
| WDPCP | WD repeat containing planar cell polarity effector | 0.0302545 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0301404 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0295816 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.02872 |
| PCBP2 | poly(rC) binding protein 2 | 0.0285202 |
| POLA1 | polymerase (DNA directed), alpha 1, catalytic subunit | 0.0285114 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0281655 |
| POTEF | POTE ankyrin domain family, member F | 0.0279225 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | 0.0266895 |
| RPS12 | ribosomal protein S12 | 0.0262552 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0255814 |
| VMP1 | vacuole membrane protein 1 | 0.0255645 |
| RPL3 | ribosomal protein L3 | 0.0249023 |
| HSPA8 | heat shock 70kDa protein 8 | 0.024612 |
| ATP11A | ATPase, class VI, type 11A | 0.0243976 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0243881 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0242435 |
| CCN2 | cellular communication network factor 2 | 0.0241966 |
| DIP2B | DIP2 disco-interacting protein 2 homolog B (Drosophila) | 0.0240127 |
| MCL1 | myeloid cell leukemia 1 | 0.0236137 |
| MSRB3 | methionine sulfoxide reductase B3 | 0.0233841 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0229564 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.02264 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0226238 |
| RCOR1 | REST corepressor 1 | 0.0222907 |
| CALR | calreticulin | 0.0222775 |
| KCMF1 | potassium channel modulatory factor 1 | 0.0222521 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.0222053 |
| BRD2 | bromodomain containing 2 | 0.0221551 |
| ANK2 | ankyrin 2, neuronal | 0.0215609 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0211619 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0210924 |
| PRELID2 | PRELI domain containing 2 | 0.0210889 |
| EPHA6 | EPH receptor A6 | 0.0210434 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0210129 |
| PIK3R3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) | 0.0209332 |
| TMEM41B | transmembrane protein 41B | 0.020923 |
| L3MBTL4 | l(3)mbt-like 4 (Drosophila) | 0.0208798 |
| ASXL2 | additional sex combs like transcriptional regulator 2 | 0.0208069 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0206163 |
| TNRC18 | trinucleotide repeat containing 18 | 0.0205901 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0205205 |
| DIAPH3 | diaphanous-related formin 3 | 0.0204463 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.020267 |
| SERTAD2 | SERTA domain containing 2 | 0.0200447 |
| ARRDC3 | arrestin domain containing 3 | 0.0199033 |
| DCAF8 | DDB1 and CUL4 associated factor 8 | 0.0198215 |
| FADS2 | fatty acid desaturase 2 | 0.0197827 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0197668 |
| PARD3B | par-3 family cell polarity regulator beta | 0.0194723 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0193845 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0192598 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 0.0191681 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0190893 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0190372 |
| RFFL | ring finger and FYVE-like domain containing E3 ubiquitin protein ligase | 0.0189598 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0188786 |
| RPTOR | regulatory associated protein of MTOR, complex 1 | 0.0187689 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0186898 |
| CLDND1 | claudin domain containing 1 | 0.0186045 |
| FLNA | filamin A, alpha | 0.0185523 |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 | 0.0184791 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0182217 |
| SMC1A | structural maintenance of chromosomes 1A | 0.0181955 |
| CPOX | coproporphyrinogen oxidase | 0.0180959 |
| DLGAP1 | discs, large (Drosophila) homolog-associated protein 1 | 0.0180154 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 0.0178158 |
| PRKCE | protein kinase C, epsilon | 0.0177529 |
| PLEC | plectin | 0.0176959 |
| FAT1 | FAT atypical cadherin 1 | 0.0176311 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0175799 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.117999 |
| MMP12 | matrix metallopeptidase 12 | -0.108396 |
| CELF2 | CUGBP, Elav-like family member 2 | -0.0863832 |
| CLDN1 | claudin 1 | -0.0779926 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.0733183 |
| VIM | vimentin | -0.0703204 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0655507 |
| AHNAK | AHNAK nucleoprotein | -0.0611424 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.0590232 |
| LMO7 | LIM domain 7 | -0.0554162 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0550823 |
| H1-0 | H1.0 linker histone | -0.0545687 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0539011 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0534137 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0517718 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | -0.0511717 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.049412 |
| RASAL2 | RAS protein activator like 2 | -0.0492592 |
| TMSB10 | thymosin beta 10 | -0.0487176 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0484409 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.045935 |
| TMEM123 | transmembrane protein 123 | -0.0453804 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0451127 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0446151 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.044239 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0440937 |
| ANXA1 | annexin A1 | -0.0439812 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0417166 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0415257 |
| DST | dystonin | -0.0413466 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | -0.04075 |
| PTMA | prothymosin, alpha | -0.0393499 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0386985 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0382237 |
| KIF5B | kinesin family member 5B | -0.0381672 |
| PGK1 | phosphoglycerate kinase 1 | -0.0372512 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0364801 |
| CARD16 | caspase recruitment domain family, member 16 | -0.0363353 |
| THOC2 | THO complex 2 | -0.0360643 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0358949 |
| NEK7 | NIMA-related kinase 7 | -0.0350061 |
| TMEM131 | transmembrane protein 131 | -0.0348113 |
| ECT2 | epithelial cell transforming 2 | -0.0337773 |
| LARS1 | leucyl-tRNA synthetase 1 | -0.0334883 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | -0.0333288 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0329081 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0325912 |
| LARP1 | La ribonucleoprotein domain family, member 1 | -0.0323699 |
| NIPSNAP2 | nipsnap homolog 2 | -0.0321306 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0312908 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0312011 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | -0.0310928 |
| XPO1 | exportin 1 | -0.0308396 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0305207 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0304705 |
| U2SURP | U2 snRNP-associated SURP domain containing | -0.0303297 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0301079 |
| SBNO1 | strawberry notch homolog 1 (Drosophila) | -0.0294854 |
| RPL12 | ribosomal protein L12 | -0.0293272 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0292317 |
| SBF2 | SET binding factor 2 | -0.0290932 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0285902 |
| NF1 | neurofibromin 1 | -0.0277946 |
| RAP1GDS1 | RAP1, GTP-GDP dissociation stimulator 1 | -0.027548 |
| PCNP | PEST proteolytic signal containing nuclear protein | -0.0273583 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0273107 |
| RPS16 | ribosomal protein S16 | -0.0268799 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | -0.0267396 |
| WDR43 | WD repeat domain 43 | -0.026634 |
| ZNF292 | zinc finger protein 292 | -0.0265195 |
| CSE1L | CSE1 chromosome segregation 1-like (yeast) | -0.0265107 |
| YBX3 | Y box binding protein 3 | -0.0263161 |
| EIF2AK1 | eukaryotic translation initiation factor 2-alpha kinase 1 | -0.0263026 |
| OXR1 | oxidation resistance 1 | -0.0262371 |
| NEBL | nebulette | -0.0261954 |
| PLK2 | polo-like kinase 2 | -0.0259104 |
| SPAG9 | sperm associated antigen 9 | -0.0254766 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0254231 |
| MAP4 | microtubule-associated protein 4 | -0.0252898 |
| NKTR | natural killer cell triggering receptor | -0.0252814 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0251926 |
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | -0.0251185 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0249727 |
| NR5A2 | nuclear receptor subfamily 5, group A, member 2 | -0.0249631 |
| ZNF217 | zinc finger protein 217 | -0.0248922 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0248683 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0246799 |
| RBM27 | RNA binding motif protein 27 | -0.0244695 |
| YES1 | YES proto-oncogene 1, Src family tyrosine kinase | -0.024454 |
| RPS24 | ribosomal protein S24 | -0.0244076 |
| RPL19 | ribosomal protein L19 | -0.0241499 |
| MAP1B | microtubule-associated protein 1B | -0.0241144 |
| WASF2 | WAS protein family, member 2 | -0.0241119 |
| TSPAN5 | tetraspanin 5 | -0.0238982 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0236585 |
| CCT5 | chaperonin containing TCP1, subunit 5 (epsilon) | -0.0236357 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0234661 |
| CAVIN1 | caveolae associated protein 1 | -0.0233375 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.0231451 |
| DHX36 | DEAH (Asp-Glu-Ala-His) box polypeptide 36 | -0.0231259 |
