| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Abiraterone acetate perturbation in A498 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Abiraterone acetate_A498 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FTH1 | ferritin, heavy polypeptide 1 | 0.130576 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0520493 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0496593 |
| ARRDC3 | arrestin domain containing 3 | 0.0492256 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0474032 |
| RTN4 | reticulon 4 | 0.0471061 |
| COL4A2 | collagen, type IV, alpha 2 | 0.0460362 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0457114 |
| RPS4X | ribosomal protein S4, X-linked | 0.0455535 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0442048 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0435758 |
| PLEC | plectin | 0.043431 |
| IRS2 | insulin receptor substrate 2 | 0.0428213 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0391062 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0386409 |
| GOLGA4 | golgin A4 | 0.0383384 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0356784 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.032963 |
| OPTN | optineurin | 0.0323568 |
| ATP13A3 | ATPase type 13A3 | 0.0320388 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0316025 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0315558 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0314378 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0313766 |
| RUNX2 | runt-related transcription factor 2 | 0.0307809 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.030354 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) | 0.0302886 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0302068 |
| GDF15 | growth differentiation factor 15 | 0.0297753 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0296586 |
| CSF1 | colony stimulating factor 1 (macrophage) | 0.0295782 |
| COG5 | component of oligomeric golgi complex 5 | 0.0290385 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.0289458 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0276318 |
| TNRC6A | trinucleotide repeat containing 6A | 0.0274296 |
| RIC1 | RAB6A GEF complex partner 1 | 0.027031 |
| FLNA | filamin A, alpha | 0.0270006 |
| PLK2 | polo-like kinase 2 | 0.0269663 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0260115 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0256107 |
| TPM3 | tropomyosin 3 | 0.0253932 |
| CLTC | clathrin, heavy chain (Hc) | 0.0251152 |
| RNF220 | ring finger protein 220 | 0.02503 |
| SBF2 | SET binding factor 2 | 0.0250183 |
| SDHA | succinate dehydrogenase complex, subunit A, flavoprotein (Fp) | 0.0246726 |
| SET | SET nuclear proto-oncogene | 0.024318 |
| PPP1R15B | protein phosphatase 1, regulatory subunit 15B | 0.0242586 |
| GNA12 | guanine nucleotide binding protein (G protein) alpha 12 | 0.0242 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0240893 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | 0.0234396 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0234191 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0231245 |
| HPCAL1 | hippocalcin-like 1 | 0.0227749 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 0.0227013 |
| STOM | stomatin | 0.0224981 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0222351 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0218498 |
| KIRREL1 | kirre like nephrin family adhesion molecule 1 | 0.0217754 |
| RPL3 | ribosomal protein L3 | 0.0217177 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0216595 |
| RPL37 | ribosomal protein L37 | 0.0216544 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | 0.021629 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0215799 |
| P3H2 | prolyl 3-hydroxylase 2 | 0.0215398 |
| RPL35 | ribosomal protein L35 | 0.0214565 |
| RNF216 | ring finger protein 216 | 0.0214368 |
| HDLBP | high density lipoprotein binding protein | 0.0213601 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0212254 |
| RPL7 | ribosomal protein L7 | 0.0210452 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0207818 |
| VPS53 | vacuolar protein sorting 53 homolog (S. cerevisiae) | 0.0207767 |
| CALR | calreticulin | 0.0207472 |
| PALS2 | protein associated with LIN7 2, MAGUK p55 family member | 0.0205541 |
| SPAG9 | sperm associated antigen 9 | 0.0204783 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | 0.020467 |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase | 0.0203358 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0203316 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0202929 |
| RPL36 | ribosomal protein L36 | 0.0202634 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0202538 |
| UPF2 | UPF2 regulator of nonsense transcripts homolog (yeast) | 0.0202299 |
| RARS1 | arginyl-tRNA synthetase 1 | 0.0202169 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.01993 |
| SNX13 | sorting nexin 13 | 0.0198432 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0198176 |
| NUDCD3 | NudC domain containing 3 | 0.0196983 |
| RPL18 | ribosomal protein L18 | 0.019605 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0195747 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | 0.0195422 |
| FAR1 | fatty acyl CoA reductase 1 | 0.0195052 |
| SEPTIN9 | septin 9 | 0.0194712 |
| ANKRD33B | ankyrin repeat domain 33B | 0.0194265 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0193955 |
| NBAS | neuroblastoma amplified sequence | 0.0193202 |
| DAPK1 | death-associated protein kinase 1 | 0.0192405 |
| EIF3B | eukaryotic translation initiation factor 3, subunit B | 0.0191782 |
| NAV2 | neuron navigator 2 | 0.0190949 |
| ATXN10 | ataxin 10 | 0.018832 |
| AP2M1 | adaptor-related protein complex 2, mu 1 subunit | 0.0187117 |
| HELZ | helicase with zinc finger | 0.0186738 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ASPH | aspartate beta-hydroxylase | -0.176452 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.124082 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.105092 |
| TXNRD1 | thioredoxin reductase 1 | -0.0968542 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0964852 |
| VIM | vimentin | -0.088475 |
| CD44 | CD44 molecule (Indian blood group) | -0.0797055 |
| CP | ceruloplasmin (ferroxidase) | -0.0765794 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0753022 |
| CA12 | carbonic anhydrase XII | -0.0717987 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0715988 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0702269 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0700986 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0669777 |
| TSHZ2 | teashirt zinc finger homeobox 2 | -0.0659302 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0633338 |
| HLA-B | major histocompatibility complex, class I, B | -0.0599867 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0555971 |
| PTMA | prothymosin, alpha | -0.0545485 |
| KYNU | kynureninase | -0.0541938 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0489489 |
| UBC | ubiquitin C | -0.0483476 |
| RPS24 | ribosomal protein S24 | -0.0470579 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0453205 |
| APOL1 | apolipoprotein L, 1 | -0.0452254 |
| RIGI | RNA sensor RIG-I | -0.0451289 |
| MAP1B | microtubule-associated protein 1B | -0.0443054 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0419181 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0399714 |
| TPM4 | tropomyosin 4 | -0.0394775 |
| FUS | FUS RNA binding protein | -0.0384665 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0375071 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.037338 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0370507 |
| JUN | jun proto-oncogene | -0.0367728 |
| TPM1 | tropomyosin 1 (alpha) | -0.0366705 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.035856 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0354395 |
| S100A10 | S100 calcium binding protein A10 | -0.0348115 |
| RAI14 | retinoic acid induced 14 | -0.0344977 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0338155 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.0329356 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0327019 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.0317784 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0309042 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0299678 |
| EHBP1 | EH domain binding protein 1 | -0.0296463 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0289646 |
| MX1 | MX dynamin-like GTPase 1 | -0.028383 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0283791 |
| ATF3 | activating transcription factor 3 | -0.0278373 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0270659 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0268904 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0265057 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0263576 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0259975 |
| INTS6 | integrator complex subunit 6 | -0.0259723 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0257792 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0257059 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0256143 |
| CLMP | CXADR-like membrane protein | -0.0251185 |
| SP100 | SP100 nuclear antigen | -0.0245538 |
| OSMR | oncostatin M receptor | -0.0244982 |
| FAM107B | family with sequence similarity 107, member B | -0.0239699 |
| RND3 | Rho family GTPase 3 | -0.0238029 |
| DGKI | diacylglycerol kinase, iota | -0.023427 |
| EGR1 | early growth response 1 | -0.0232993 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | -0.0230417 |
| RHEB | Ras homolog enriched in brain | -0.0230232 |
| XAF1 | XIAP associated factor 1 | -0.0229545 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0225904 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.0222442 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0221922 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0219443 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0219275 |
| CUX1 | cut-like homeobox 1 | -0.0218626 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0217701 |
| GCLM | glutamate-cysteine ligase, modifier subunit | -0.0216942 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0215374 |
| IER3 | immediate early response 3 | -0.0214584 |
| GLIS3 | GLIS family zinc finger 3 | -0.021457 |
| IL6 | interleukin 6 | -0.0214338 |
| TMEM263 | transmembrane protein 263 | -0.0212564 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0212519 |
| RPL7A | ribosomal protein L7a | -0.0212003 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.02079 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.0207824 |
| PKM | pyruvate kinase, muscle | -0.0207372 |
| CAVIN1 | caveolae associated protein 1 | -0.020724 |
| CDCP1 | CUB domain containing protein 1 | -0.020575 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0204315 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.020376 |
| RPS15 | ribosomal protein S15 | -0.0201593 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | -0.0201012 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0199976 |
| TGM2 | transglutaminase 2 | -0.0199469 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0198336 |
| ANXA1 | annexin A1 | -0.0197311 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0196777 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0193951 |
