| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Abiraterone acetate perturbation in A549 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Abiraterone acetate_A549 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.110958 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.106221 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0903911 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0687916 |
| ANXA2 | annexin A2 | 0.0655222 |
| SPAG9 | sperm associated antigen 9 | 0.0565638 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.054886 |
| HELZ | helicase with zinc finger | 0.0519404 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0503964 |
| USP3 | ubiquitin specific peptidase 3 | 0.0498238 |
| KCTD9 | potassium channel tetramerization domain containing 9 | 0.0482084 |
| GOLGA4 | golgin A4 | 0.047184 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0427419 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0414811 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0400531 |
| NUP58 | nucleoporin 58 | 0.0378024 |
| NDRG1 | N-myc downstream regulated 1 | 0.0370308 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0363435 |
| WDR45B | WD repeat domain 45B | 0.0360507 |
| OGA | O-GlcNAcase | 0.0359551 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0352189 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0331162 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0328614 |
| FLNB | filamin B, beta | 0.0323901 |
| SEPTIN2 | septin 2 | 0.0323052 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0311296 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0307098 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0305255 |
| CEP95 | centrosomal protein 95kDa | 0.0303216 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0302329 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0295573 |
| RASA2 | RAS p21 protein activator 2 | 0.0292876 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0290843 |
| NAV2 | neuron navigator 2 | 0.0289968 |
| SBF2 | SET binding factor 2 | 0.02871 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0284694 |
| SMAD3 | SMAD family member 3 | 0.0278987 |
| PMM2 | phosphomannomutase 2 | 0.027705 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0275408 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0266473 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0265909 |
| CLINT1 | clathrin interactor 1 | 0.0258675 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0258545 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.025831 |
| TFG | TRK-fused gene | 0.0256698 |
| LOC112694756 | uncharaterized LOC112694756 | 0.025573 |
| THOC2 | THO complex 2 | 0.025396 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0253667 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.024551 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0244897 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.024161 |
| MORF4L2 | mortality factor 4 like 2 | 0.0241083 |
| SRP54 | signal recognition particle 54kDa | 0.02377 |
| MYOF | myoferlin | 0.0229579 |
| FMNL2 | formin-like 2 | 0.0220947 |
| CLTC | clathrin, heavy chain (Hc) | 0.0220263 |
| CASC3 | cancer susceptibility candidate 3 | 0.0219982 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0218527 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0216457 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0214065 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0213358 |
| MT1X | metallothionein 1X | 0.0211802 |
| VEZT | vezatin, adherens junctions transmembrane protein | 0.020942 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0207357 |
| ABTB3 | ankyrin repeat and BTB domain containing 3 | 0.0204953 |
| ANLN | anillin, actin binding protein | 0.0202039 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0199759 |
| RRBP1 | ribosome binding protein 1 | 0.019966 |
| SKIC3 | SKI3 subunit of superkiller complex | 0.019954 |
| YBX1 | Y box binding protein 1 | 0.0198518 |
| CDC27 | cell division cycle 27 | 0.0198348 |
| C1D | C1D nuclear receptor corepressor | 0.0198071 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.019734 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0197166 |
| QKI | QKI, KH domain containing, RNA binding | 0.019647 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0195192 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | 0.0194323 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0193949 |
| FGD6 | FYVE, RhoGEF and PH domain containing 6 | 0.0193572 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0193131 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0191007 |
| WDR43 | WD repeat domain 43 | 0.0189671 |
| UBE2O | ubiquitin-conjugating enzyme E2O | 0.0187592 |
| KIF16B | kinesin family member 16B | 0.0187332 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0187225 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 0.0186876 |
| MIS18BP1 | MIS18 binding protein 1 | 0.0186768 |
| RPL12 | ribosomal protein L12 | 0.0185528 |
| ATP13A3 | ATPase type 13A3 | 0.0184545 |
| PLEC | plectin | 0.0183675 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0183052 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0182161 |
| RARS1 | arginyl-tRNA synthetase 1 | 0.0181965 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.0181699 |
| GOLGA2 | golgin A2 | 0.0181422 |
| ZNF292 | zinc finger protein 292 | 0.0180903 |
| ENTPD7 | ectonucleoside triphosphate diphosphohydrolase 7 | 0.0179145 |
| TOP1 | topoisomerase (DNA) I | 0.0178103 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0177989 |
| RTN4 | reticulon 4 | 0.0173508 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.218226 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.137247 |
| VIM | vimentin | -0.100473 |
| KYNU | kynureninase | -0.0916308 |
| KRT81 | keratin 81, type II | -0.0882926 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0757303 |
| PDE10A | phosphodiesterase 10A | -0.0710873 |
| FTL | ferritin, light polypeptide | -0.0704243 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | -0.0667298 |
| TXNRD1 | thioredoxin reductase 1 | -0.0661726 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0650122 |
| ASPH | aspartate beta-hydroxylase | -0.0644453 |
| TMSB10 | thymosin beta 10 | -0.0633611 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0622418 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0621848 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0621324 |
| CA12 | carbonic anhydrase XII | -0.060003 |
| PKM | pyruvate kinase, muscle | -0.0587737 |
| POTEF | POTE ankyrin domain family, member F | -0.0583437 |
| RPS23 | ribosomal protein S23 | -0.0524346 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0515065 |
| UBC | ubiquitin C | -0.0484973 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.0473254 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0467515 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0466215 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0454624 |
| MCL1 | myeloid cell leukemia 1 | -0.0427499 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0410033 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0404012 |
| LDHA | lactate dehydrogenase A | -0.0393614 |
| RPS13 | ribosomal protein S13 | -0.0381547 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0381197 |
| RPS11 | ribosomal protein S11 | -0.0380174 |
| GLIS3 | GLIS family zinc finger 3 | -0.037706 |
| VMP1 | vacuole membrane protein 1 | -0.0375462 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0368402 |
| RPS16 | ribosomal protein S16 | -0.0361709 |
| RPS24 | ribosomal protein S24 | -0.0360755 |
| SP100 | SP100 nuclear antigen | -0.035468 |
| RPL28 | ribosomal protein L28 | -0.0350158 |
| EGR1 | early growth response 1 | -0.0349361 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | -0.0348879 |
| PTMA | prothymosin, alpha | -0.0348656 |
| RPL31 | ribosomal protein L31 | -0.0338673 |
| S100A10 | S100 calcium binding protein A10 | -0.0332452 |
| RPS6 | ribosomal protein S6 | -0.032954 |
| RPS29 | ribosomal protein S29 | -0.0325974 |
| TPM4 | tropomyosin 4 | -0.032249 |
| WWOX | WW domain containing oxidoreductase | -0.0320874 |
| MAP1B | microtubule-associated protein 1B | -0.0317347 |
| BPTF | bromodomain PHD finger transcription factor | -0.0316387 |
| RIGI | RNA sensor RIG-I | -0.031348 |
| RPL7A | ribosomal protein L7a | -0.030695 |
| RHCG | Rh family, C glycoprotein | -0.0299674 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0297987 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0297076 |
| RPS27A | ribosomal protein S27a | -0.0289261 |
| KRT7 | keratin 7, type II | -0.0288163 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0283024 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0281968 |
| FOXP1 | forkhead box P1 | -0.028018 |
| CUX1 | cut-like homeobox 1 | -0.0279148 |
| EHBP1 | EH domain binding protein 1 | -0.0278663 |
| PALLD | palladin, cytoskeletal associated protein | -0.0271916 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0271646 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.0270068 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0267471 |
| RNF213 | ring finger protein 213 | -0.0264232 |
| NRP1 | neuropilin 1 | -0.0262236 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 | -0.0262185 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | -0.0260365 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0259255 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0257771 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.025182 |
| CD44 | CD44 molecule (Indian blood group) | -0.0251533 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0247986 |
| B2M | beta-2-microglobulin | -0.0246725 |
| NRG1 | neuregulin 1 | -0.0246054 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0243586 |
| RPL37A | ribosomal protein L37a | -0.0242819 |
| RPLP2 | ribosomal protein, large, P2 | -0.0242457 |
| TCIM | transcriptional and immune response regulator | -0.0241381 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0233405 |
| RAB10 | RAB10, member RAS oncogene family | -0.0232104 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0231735 |
| PFN1 | profilin 1 | -0.0231648 |
| RPL8 | ribosomal protein L8 | -0.0230649 |
| ENO1 | enolase 1, (alpha) | -0.0228731 |
| RAD51B | RAD51 paralog B | -0.0226349 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0224735 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0224395 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0223934 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0223432 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0223159 |
| EZR | ezrin | -0.0223134 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0222819 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.022278 |
| WASF2 | WAS protein family, member 2 | -0.0221449 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0220611 |
| GRAMD1B | GRAM domain containing 1B | -0.0218352 |
