| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Abiraterone acetate perturbation in AsPC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Abiraterone acetate_AsPC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LAMB3 | laminin, beta 3 | 0.0888517 |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 | 0.0608641 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0420781 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.037913 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.032153 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0286978 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.0271714 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0266088 |
| KLK10 | kallikrein-related peptidase 10 | 0.0248172 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.0247144 |
| NDRG1 | N-myc downstream regulated 1 | 0.0242608 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0235176 |
| MUC17 | mucin 17, cell surface associated | 0.0230934 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0230925 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.022682 |
| RPL35A | ribosomal protein L35a | 0.0212324 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.020945 |
| TMBIM1 | transmembrane BAX inhibitor motif containing 1 | 0.0197381 |
| MXD1 | MAX dimerization protein 1 | 0.0197254 |
| PLEC | plectin | 0.0193518 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0192625 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | 0.0190526 |
| ATG16L1 | autophagy related 16-like 1 (S. cerevisiae) | 0.0177384 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0171926 |
| CSTB | cystatin B (stefin B) | 0.0158713 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0150191 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0144994 |
| KIRREL1 | kirre like nephrin family adhesion molecule 1 | 0.0144722 |
| OPTN | optineurin | 0.014217 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.013988 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0138665 |
| HLA-C | major histocompatibility complex, class I, C | 0.0137199 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0134969 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.0133215 |
| FAM13A | family with sequence similarity 13, member A | 0.0130894 |
| LMO7 | LIM domain 7 | 0.0130582 |
| RPL34 | ribosomal protein L34 | 0.0129648 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0128484 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0123548 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0120096 |
| LASP1 | LIM and SH3 protein 1 | 0.0118945 |
| ERGIC1 | endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1 | 0.011781 |
| GUK1 | guanylate kinase 1 | 0.0117209 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0116439 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.0115859 |
| SLC9A3R2 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2 | 0.0114343 |
| NPSR1 | neuropeptide S receptor 1 | 0.0111583 |
| INPP5D | inositol polyphosphate-5-phosphatase, 145kDa | 0.0111193 |
| INSIG2 | insulin induced gene 2 | 0.0109945 |
| RPL41 | ribosomal protein L41 | 0.0109447 |
| PDXK | pyridoxal (pyridoxine, vitamin B6) kinase | 0.0109314 |
| CD164 | CD164 molecule, sialomucin | 0.0109241 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | 0.0106747 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0106356 |
| DPY19L1 | dpy-19-like 1 (C. elegans) | 0.0106191 |
| SACK1A | scaffolding CK1 anchoring protein A | 0.0105631 |
| JUP | junction plakoglobin | 0.0105051 |
| PEAR1 | platelet endothelial aggregation receptor 1 | 0.010296 |
| SCFD2 | sec1 family domain containing 2 | 0.0102291 |
| PRRC1 | proline-rich coiled-coil 1 | 0.0102169 |
| SULF2 | sulfatase 2 | 0.0101368 |
| PLEK2 | pleckstrin 2 | 0.00991854 |
| HELZ | helicase with zinc finger | 0.00957078 |
| ARF1 | ADP-ribosylation factor 1 | 0.00951479 |
| FERMT1 | fermitin family member 1 | 0.00950396 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.00947331 |
| INPP1 | inositol polyphosphate-1-phosphatase | 0.00946304 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.00941087 |
| EFNA1 | ephrin-A1 | 0.00924908 |
| NUP58 | nucleoporin 58 | 0.00909027 |
| MXI1 | MAX interactor 1, dimerization protein | 0.00898621 |
| FN1 | fibronectin 1 | 0.00897218 |
| EGR1 | early growth response 1 | 0.00897144 |
| SMC3 | structural maintenance of chromosomes 3 | 0.00892075 |
| TINAGL1 | tubulointerstitial nephritis antigen-like 1 | 0.00891614 |
| SRPRA | SRP receptor subunit alpha | 0.00881125 |
| CD68 | CD68 molecule | 0.00862695 |
| RCOR1 | REST corepressor 1 | 0.00845608 |
| LIMA1 | LIM domain and actin binding 1 | 0.00841249 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.00826983 |
| CLINT1 | clathrin interactor 1 | 0.00819951 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.00811129 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.00810108 |
| SEC24C | SEC24 family member C | 0.00807798 |
| RAP1GAP2 | RAP1 GTPase activating protein 2 | 0.0080541 |
| S100A4 | S100 calcium binding protein A4 | 0.00803501 |
| DSC3 | desmocollin 3 | 0.00795678 |
| LAMA5 | laminin, alpha 5 | 0.0079506 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | 0.00793851 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.00788367 |
| S100A11 | S100 calcium binding protein A11 | 0.00784932 |
| RAB5B | RAB5B, member RAS oncogene family | 0.00782389 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.00780134 |
| SEC61G | Sec61 gamma subunit | 0.00779997 |
| ERI2 | ERI1 exoribonuclease family member 2 | 0.00750675 |
| SP100 | SP100 nuclear antigen | 0.00750052 |
| WDR45B | WD repeat domain 45B | 0.0074691 |
| ANXA2 | annexin A2 | 0.007457 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | 0.00745549 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.00742518 |
| Symbol | Name | Standardized Value |
|---|---|---|
| UBC | ubiquitin C | -0.271718 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.12555 |
| AHNAK | AHNAK nucleoprotein | -0.11659 |
| TMSB10 | thymosin beta 10 | -0.116028 |
| VIM | vimentin | -0.107465 |
| POTEF | POTE ankyrin domain family, member F | -0.10495 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.099061 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0904166 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0860217 |
| ASPH | aspartate beta-hydroxylase | -0.0844914 |
| TXNRD1 | thioredoxin reductase 1 | -0.0842682 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0705198 |
| ITGA6 | integrin, alpha 6 | -0.0697065 |
| SMAD3 | SMAD family member 3 | -0.0687244 |
| RPS27A | ribosomal protein S27a | -0.0644694 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0642789 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0609619 |
| S100A10 | S100 calcium binding protein A10 | -0.0607758 |
| PCBP2 | poly(rC) binding protein 2 | -0.0590113 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0579229 |
| EGFR | epidermal growth factor receptor | -0.0562672 |
| EFNA5 | ephrin-A5 | -0.0540513 |
| RTN4 | reticulon 4 | -0.0533584 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0519801 |
| LDHA | lactate dehydrogenase A | -0.0495684 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0463942 |
| LMTK2 | lemur tyrosine kinase 2 | -0.0452217 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.0445224 |
| PTMA | prothymosin, alpha | -0.0436793 |
| KRT8 | keratin 8, type II | -0.0433631 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0425018 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0413171 |
| PRRC2C | proline-rich coiled-coil 2C | -0.041296 |
| TPM3 | tropomyosin 3 | -0.0398317 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0388098 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0374361 |
| SQSTM1 | sequestosome 1 | -0.0373649 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.037064 |
| CAB39 | calcium binding protein 39 | -0.0368485 |
| VCAN | versican | -0.0361885 |
| EZR | ezrin | -0.0361187 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0359736 |
| MYOF | myoferlin | -0.0349756 |
| FOXO1 | forkhead box O1 | -0.0348442 |
| FLNB | filamin B, beta | -0.0348342 |
| ARHGAP42 | Rho GTPase activating protein 42 | -0.0343904 |
| SDC4 | syndecan 4 | -0.0343464 |
| EMP1 | epithelial membrane protein 1 | -0.0333753 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0329481 |
| RAB10 | RAB10, member RAS oncogene family | -0.0326819 |
| MED13L | mediator complex subunit 13-like | -0.0326642 |
| CDCP1 | CUB domain containing protein 1 | -0.0325597 |
| TOP1 | topoisomerase (DNA) I | -0.0324393 |
| ARPC1B | actin related protein 2/3 complex, subunit 1B, 41kDa | -0.0322719 |
| VMP1 | vacuole membrane protein 1 | -0.0319441 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0315904 |
| APP | amyloid beta (A4) precursor protein | -0.0313345 |
| JMJD1C | jumonji domain containing 1C | -0.0309671 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0307997 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0306737 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | -0.0303095 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0298229 |
| CORO1C | coronin, actin binding protein, 1C | -0.0297562 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | -0.029689 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0296822 |
| SKAP2 | src kinase associated phosphoprotein 2 | -0.0295993 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0295302 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | -0.0293444 |
| VCL | vinculin | -0.02931 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0291666 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0291342 |
| TGM2 | transglutaminase 2 | -0.0290708 |
| RHEB | Ras homolog enriched in brain | -0.0290077 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | -0.0289524 |
| IPO7 | importin 7 | -0.0283919 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0283449 |
| PTK2 | protein tyrosine kinase 2 | -0.0283085 |
| RBM25 | RNA binding motif protein 25 | -0.028308 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0282844 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0282286 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | -0.0282247 |
| PARD3 | par-3 family cell polarity regulator | -0.0281265 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0280984 |
| NCOA3 | nuclear receptor coactivator 3 | -0.0280072 |
| NEK7 | NIMA-related kinase 7 | -0.0275553 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0274813 |
| FGD6 | FYVE, RhoGEF and PH domain containing 6 | -0.0273257 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0271711 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.02713 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0270675 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0270394 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0270004 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0266963 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 | -0.0263657 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0263625 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0262828 |
| TPM4 | tropomyosin 4 | -0.026244 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.026096 |
| USP34 | ubiquitin specific peptidase 34 | -0.0258247 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | -0.0258026 |
