| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Abiraterone acetate perturbation in C32 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Abiraterone acetate_C32 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.185833 |
| CD109 | CD109 molecule | 0.0672758 |
| NDRG1 | N-myc downstream regulated 1 | 0.0605558 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0450828 |
| VGF | VGF nerve growth factor inducible | 0.0399783 |
| PPFIA4 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 | 0.0383369 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0375998 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0333453 |
| KIRREL1 | kirre like nephrin family adhesion molecule 1 | 0.0316603 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0304904 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0302244 |
| TMEM178B | transmembrane protein 178B | 0.0297038 |
| LEF1 | lymphoid enhancer-binding factor 1 | 0.0292766 |
| ARRDC3 | arrestin domain containing 3 | 0.0283926 |
| A2M | alpha-2-macroglobulin | 0.0283549 |
| RNASE12 | ribonuclease, RNase A family, 12 (non-active) | 0.0252266 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0243005 |
| MIDEAS | mitotic deacetylase associated SANT domain protein | 0.0230936 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0230512 |
| CABIN1 | calcineurin binding protein 1 | 0.0228922 |
| FBXO7 | F-box protein 7 | 0.0228585 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0223587 |
| SETBP1 | SET binding protein 1 | 0.0210221 |
| SSBP3 | single stranded DNA binding protein 3 | 0.0205848 |
| RPL3 | ribosomal protein L3 | 0.0204831 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0203572 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0203519 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0201484 |
| FLNA | filamin A, alpha | 0.0198809 |
| PRELID2 | PRELI domain containing 2 | 0.0198573 |
| NBAS | neuroblastoma amplified sequence | 0.0191658 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0185255 |
| PLEC | plectin | 0.0182629 |
| MCL1 | myeloid cell leukemia 1 | 0.0178762 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0177223 |
| TMEM255B | transmembrane protein 255B | 0.0161692 |
| ZYX | zyxin | 0.0161163 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0158823 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0158357 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0143606 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0142462 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0140569 |
| NUP58 | nucleoporin 58 | 0.01397 |
| ACTN1 | actinin, alpha 1 | 0.0138937 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0137468 |
| STRIP2 | striatin interacting protein 2 | 0.0137342 |
| RNF150 | ring finger protein 150 | 0.0135824 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0135504 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0133914 |
| ETV3 | ets variant 3 | 0.013212 |
| RNF213 | ring finger protein 213 | 0.0130873 |
| WWP2 | WW domain containing E3 ubiquitin protein ligase 2 | 0.013071 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0130178 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0130095 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0127987 |
| HLA-C | major histocompatibility complex, class I, C | 0.012753 |
| FYN | FYN proto-oncogene, Src family tyrosine kinase | 0.0122955 |
| RELT | RELT tumor necrosis factor receptor | 0.0122467 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 | 0.0121919 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0121774 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0120593 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0120276 |
| IVNS1ABP | influenza virus NS1A binding protein | 0.0120127 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0119011 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0117769 |
| STOM | stomatin | 0.0117041 |
| SOX13 | SRY (sex determining region Y)-box 13 | 0.0114602 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.0114447 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0113613 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | 0.0112654 |
| PRRC2A | proline-rich coiled-coil 2A | 0.0111545 |
| DCAF8 | DDB1 and CUL4 associated factor 8 | 0.0111444 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0111058 |
| SERGEF | secretion regulating guanine nucleotide exchange factor | 0.0110334 |
| SCARB1 | scavenger receptor class B, member 1 | 0.0110227 |
| EXOC4 | exocyst complex component 4 | 0.010991 |
| VEGFA | vascular endothelial growth factor A | 0.010956 |
| TMF1 | TATA element modulatory factor 1 | 0.0109364 |
| PPME1 | protein phosphatase methylesterase 1 | 0.0108999 |
| TNFRSF14 | tumor necrosis factor receptor superfamily, member 14 | 0.0108826 |
| FRMD6 | FERM domain containing 6 | 0.0108039 |
| FOSL1 | FOS-like antigen 1 | 0.0106801 |
| CHSY1 | chondroitin sulfate synthase 1 | 0.0103084 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | 0.0102598 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.010085 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | 0.0100233 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.00977458 |
| PLXNB2 | plexin B2 | 0.00972825 |
| TBC1D22A | TBC1 domain family, member 22A | 0.00972347 |
| RIPK4 | receptor-interacting serine-threonine kinase 4 | 0.00971834 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.00964623 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | 0.00957715 |
| GRAMD4 | GRAM domain containing 4 | 0.00956486 |
| SEC24D | SEC24 family member D | 0.00953383 |
| BCL9L | B-cell CLL/lymphoma 9-like | 0.00942937 |
| IQGAP3 | IQ motif containing GTPase activating protein 3 | 0.00911951 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | 0.00909467 |
| EFCAB13 | EF-hand calcium binding domain 13 | 0.00906849 |
| NEK6 | NIMA-related kinase 6 | 0.00903305 |
| SYNM | synemin, intermediate filament protein | 0.00900893 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.522012 |
| VIM | vimentin | -0.2889 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.173938 |
| FMN1 | formin 1 | -0.0953736 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0913666 |
| TMSB10 | thymosin beta 10 | -0.0883911 |
| HLA-B | major histocompatibility complex, class I, B | -0.0882972 |
| GPC6 | glypican 6 | -0.0880112 |
| MT2A | metallothionein 2A | -0.0806701 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0805457 |
| S100A6 | S100 calcium binding protein A6 | -0.0762363 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0725292 |
| NLGN1 | neuroligin 1 | -0.0702446 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0641037 |
| RPLP1 | ribosomal protein, large, P1 | -0.0599875 |
| PTMA | prothymosin, alpha | -0.0576219 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0540461 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0530222 |
| ACTG1 | actin gamma 1 | -0.0527034 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0470102 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.0447672 |
| IER3 | immediate early response 3 | -0.0439814 |
| DCT | dopachrome tautomerase | -0.0436395 |
| PGK1 | phosphoglycerate kinase 1 | -0.0432195 |
| FTL | ferritin, light polypeptide | -0.0412395 |
| GDF15 | growth differentiation factor 15 | -0.0409979 |
| S100A9 | S100 calcium binding protein A9 | -0.0409718 |
| RHEB | Ras homolog enriched in brain | -0.0407023 |
| SRPK2 | SRSF protein kinase 2 | -0.0406928 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0403335 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0403225 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0391031 |
| RPS8 | ribosomal protein S8 | -0.037738 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0376984 |
| RPLP2 | ribosomal protein, large, P2 | -0.0365122 |
| ENO1 | enolase 1, (alpha) | -0.0364457 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0363433 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0359777 |
| CALD1 | caldesmon 1 | -0.0358395 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0354152 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0352322 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0347744 |
| S100A10 | S100 calcium binding protein A10 | -0.0340862 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0337175 |
| TAGLN2 | transgelin 2 | -0.0334773 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0329544 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0327624 |
| MTPN | myotrophin | -0.0327517 |
| LAMB1 | laminin, beta 1 | -0.0318107 |
| ARPC1B | actin related protein 2/3 complex, subunit 1B, 41kDa | -0.0316913 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0316133 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0315715 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0315054 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0312 |
| RPL37A | ribosomal protein L37a | -0.0307979 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0303347 |
| RPS19 | ribosomal protein S19 | -0.030319 |
| CUX1 | cut-like homeobox 1 | -0.0302703 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.030069 |
| GNAS | GNAS complex locus | -0.0299677 |
| RPS6 | ribosomal protein S6 | -0.0297855 |
| CD63 | CD63 molecule | -0.0292457 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0287608 |
| EHBP1 | EH domain binding protein 1 | -0.0287195 |
| POTEF | POTE ankyrin domain family, member F | -0.028671 |
| CALU | calumenin | -0.0286055 |
| FUS | FUS RNA binding protein | -0.0283028 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.0282944 |
| RPL35A | ribosomal protein L35a | -0.0278803 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.027413 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0270969 |
| COL19A1 | collagen, type XIX, alpha 1 | -0.026612 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0265795 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0265584 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0265583 |
| RPL34 | ribosomal protein L34 | -0.0263915 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0259691 |
| FRMD4A | FERM domain containing 4A | -0.0258882 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0257449 |
| RPL19 | ribosomal protein L19 | -0.0257062 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0256608 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0256587 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0256179 |
| RPLP0 | ribosomal protein, large, P0 | -0.0254939 |
| EGR1 | early growth response 1 | -0.0253245 |
| RLF | rearranged L-myc fusion | -0.0252576 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0250104 |
| PKM | pyruvate kinase, muscle | -0.0243541 |
| B2M | beta-2-microglobulin | -0.0242938 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0241314 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.024083 |
| FBXO11 | F-box protein 11 | -0.0239521 |
| RPL12 | ribosomal protein L12 | -0.0237672 |
| MMP16 | matrix metallopeptidase 16 (membrane-inserted) | -0.0235159 |
| COG5 | component of oligomeric golgi complex 5 | -0.0231634 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.022896 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.022781 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.0227003 |
| SEPTIN7 | septin 7 | -0.0226759 |
| OSMR | oncostatin M receptor | -0.0225838 |