| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Abiraterone acetate perturbation in CFPAC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Abiraterone acetate_CFPAC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0832278 |
| DTNA | dystrobrevin, alpha | 0.0819467 |
| LAMB3 | laminin, beta 3 | 0.0767157 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0731048 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0716976 |
| HLA-C | major histocompatibility complex, class I, C | 0.0677968 |
| NDRG1 | N-myc downstream regulated 1 | 0.0614374 |
| FLNB | filamin B, beta | 0.0608819 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0564434 |
| SPAG9 | sperm associated antigen 9 | 0.0547187 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0524145 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.051971 |
| CCNY | cyclin Y | 0.0506021 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.048845 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0453029 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0452005 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0439913 |
| PLEC | plectin | 0.0438008 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0389918 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | 0.0379579 |
| FAM13A | family with sequence similarity 13, member A | 0.0362699 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0362249 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0356606 |
| OGA | O-GlcNAcase | 0.0339069 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0335684 |
| FNBP1L | formin binding protein 1-like | 0.0331832 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.032005 |
| MEF2A | myocyte enhancer factor 2A | 0.0319022 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0310663 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0300594 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0292666 |
| HELZ | helicase with zinc finger | 0.0291603 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0287294 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0282957 |
| RTN4 | reticulon 4 | 0.0275284 |
| NUP58 | nucleoporin 58 | 0.0273518 |
| OPTN | optineurin | 0.0272521 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0271612 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0268999 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0263796 |
| YTHDC1 | YTH domain containing 1 | 0.0261721 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.0257007 |
| CDC73 | cell division cycle 73 | 0.0255375 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.025326 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0249464 |
| RASA2 | RAS p21 protein activator 2 | 0.0246647 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.024519 |
| IRF6 | interferon regulatory factor 6 | 0.0238278 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0237547 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0235484 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0231374 |
| ATP11B | ATPase, class VI, type 11B | 0.0230854 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0230466 |
| SUCO | SUN domain containing ossification factor | 0.0229626 |
| TFG | TRK-fused gene | 0.0229492 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0221147 |
| WDR45B | WD repeat domain 45B | 0.0219962 |
| MYO5B | myosin VB | 0.021464 |
| MYO1B | myosin IB | 0.0213012 |
| KIRREL1 | kirre like nephrin family adhesion molecule 1 | 0.0212655 |
| MCU | mitochondrial calcium uniporter | 0.0209328 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0207376 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0204979 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | 0.0202278 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.019971 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.019849 |
| RBM39 | RNA binding motif protein 39 | 0.0194441 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0194386 |
| FGD6 | FYVE, RhoGEF and PH domain containing 6 | 0.0193631 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0190557 |
| COPA | coatomer protein complex, subunit alpha | 0.0190403 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.0188467 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0187824 |
| RCOR1 | REST corepressor 1 | 0.0185433 |
| RLF | rearranged L-myc fusion | 0.0185061 |
| CASC3 | cancer susceptibility candidate 3 | 0.0183283 |
| VEZT | vezatin, adherens junctions transmembrane protein | 0.0182819 |
| PARD3 | par-3 family cell polarity regulator | 0.017994 |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 | 0.0172763 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0169926 |
| FLNA | filamin A, alpha | 0.0169545 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0168268 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.016739 |
| CUL3 | cullin 3 | 0.0167244 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0167004 |
| AFDN | afadin, adherens junction formation factor | 0.0166994 |
| ABI1 | abl-interactor 1 | 0.0166289 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0166225 |
| TPM3 | tropomyosin 3 | 0.01658 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.0164584 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0163786 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0163176 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0161834 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0159845 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0159366 |
| KDM5B | lysine (K)-specific demethylase 5B | 0.0159248 |
| HSPG2 | heparan sulfate proteoglycan 2 | 0.0158704 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0158148 |
| SEMA7A | semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group) | 0.0157539 |
| RUNX1 | runt-related transcription factor 1 | 0.0156567 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.23694 |
| PTMA | prothymosin, alpha | -0.123679 |
| HLA-B | major histocompatibility complex, class I, B | -0.104604 |
| CP | ceruloplasmin (ferroxidase) | -0.0930169 |
| APOL1 | apolipoprotein L, 1 | -0.0863147 |
| MT2A | metallothionein 2A | -0.0847564 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0816363 |
| TMSB10 | thymosin beta 10 | -0.0719901 |
| MMP7 | matrix metallopeptidase 7 | -0.0715687 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0707174 |
| B2M | beta-2-microglobulin | -0.0695693 |
| FTL | ferritin, light polypeptide | -0.0572943 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0568135 |
| RNF213 | ring finger protein 213 | -0.0563257 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0554696 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0552678 |
| ASPH | aspartate beta-hydroxylase | -0.0546465 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0540145 |
| KRT19 | keratin 19, type I | -0.0521523 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.051392 |
| UBC | ubiquitin C | -0.0511802 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.051086 |
| VIM | vimentin | -0.0509237 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0505289 |
| PKM | pyruvate kinase, muscle | -0.0483188 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0480489 |
| LCN2 | lipocalin 2 | -0.0479062 |
| ENO1 | enolase 1, (alpha) | -0.0478261 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0469778 |
| RPS24 | ribosomal protein S24 | -0.0459793 |
| RPS29 | ribosomal protein S29 | -0.0453355 |
| RPS8 | ribosomal protein S8 | -0.04478 |
| S100A10 | S100 calcium binding protein A10 | -0.0436024 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0435788 |
| IER3 | immediate early response 3 | -0.0435077 |
| MX1 | MX dynamin-like GTPase 1 | -0.0433437 |
| EFNA5 | ephrin-A5 | -0.043333 |
| SP100 | SP100 nuclear antigen | -0.0420299 |
| TXNIP | thioredoxin interacting protein | -0.0419447 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0414738 |
| NRG3 | neuregulin 3 | -0.0406269 |
| MX2 | MX dynamin-like GTPase 2 | -0.0401472 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0400125 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0398646 |
| EGR1 | early growth response 1 | -0.0398216 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0395464 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0390923 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0380884 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0368875 |
| KLF6 | Kruppel-like factor 6 | -0.0365197 |
| RPL19 | ribosomal protein L19 | -0.0364855 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0360575 |
| RPL23 | ribosomal protein L23 | -0.0355279 |
| RPS23 | ribosomal protein S23 | -0.0353549 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0351849 |
| TGM2 | transglutaminase 2 | -0.0343173 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0334269 |
| HLA-E | major histocompatibility complex, class I, E | -0.033323 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0332776 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0330635 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0326835 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0324685 |
| RPLP1 | ribosomal protein, large, P1 | -0.0324171 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0320126 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0318025 |
| CANX | calnexin | -0.0316904 |
| PCDH7 | protocadherin 7 | -0.0315465 |
| IRAK3 | interleukin-1 receptor-associated kinase 3 | -0.0311883 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0309556 |
| RPL31 | ribosomal protein L31 | -0.0307412 |
| RPS25 | ribosomal protein S25 | -0.0306431 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.0301389 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0296098 |
| NABP1 | nucleic acid binding protein 1 | -0.0295536 |
| PMP22 | peripheral myelin protein 22 | -0.0295079 |
| TMC5 | transmembrane channel-like 5 | -0.029175 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0290315 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0284207 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0283468 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0280965 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0280028 |
| RPL35A | ribosomal protein L35a | -0.0279843 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0279657 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0279261 |
| RIGI | RNA sensor RIG-I | -0.0278042 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0277935 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0274959 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0273822 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0273812 |
| RPLP2 | ribosomal protein, large, P2 | -0.0273135 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | -0.0271782 |
| OSMR | oncostatin M receptor | -0.0264865 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.0263063 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0260159 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0256765 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0255168 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.0254873 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0254002 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0250156 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0246843 |
