| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Abiraterone acetate perturbation in H4 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Abiraterone acetate_H4 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NDRG1 | N-myc downstream regulated 1 | 0.0929413 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0750751 |
| MT2A | metallothionein 2A | 0.0738882 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0534239 |
| EGFR | epidermal growth factor receptor | 0.0461422 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0424262 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0413969 |
| PLEC | plectin | 0.0402027 |
| VEGFA | vascular endothelial growth factor A | 0.0393898 |
| RPL35A | ribosomal protein L35a | 0.0378806 |
| RPL37A | ribosomal protein L37a | 0.0346352 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0339159 |
| TPM3 | tropomyosin 3 | 0.0334818 |
| RPL34 | ribosomal protein L34 | 0.0328885 |
| MSN | moesin | 0.0327444 |
| RPL3 | ribosomal protein L3 | 0.0304346 |
| RPS12 | ribosomal protein S12 | 0.0301316 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0295043 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.02805 |
| YEATS2 | YEATS domain containing 2 | 0.0263673 |
| DTNA | dystrobrevin, alpha | 0.0262013 |
| RACK1 | receptor for activated C kinase 1 | 0.0259792 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0259386 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0257861 |
| RPLP2 | ribosomal protein, large, P2 | 0.025387 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0248627 |
| RPS17 | ribosomal protein S17 | 0.0247945 |
| RPS8 | ribosomal protein S8 | 0.0243175 |
| TPI1 | triosephosphate isomerase 1 | 0.0243143 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0241951 |
| RPL23 | ribosomal protein L23 | 0.0238556 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.023827 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0231395 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0224735 |
| PRKCE | protein kinase C, epsilon | 0.0221521 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0221115 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0219847 |
| PRRC2A | proline-rich coiled-coil 2A | 0.0219157 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0216921 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0215129 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0214515 |
| SET | SET nuclear proto-oncogene | 0.0214145 |
| FOSL1 | FOS-like antigen 1 | 0.0211629 |
| FAM219A | family with sequence similarity 219, member A | 0.0210804 |
| RPL7 | ribosomal protein L7 | 0.0206337 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0205585 |
| FAM13A | family with sequence similarity 13, member A | 0.0205317 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0205247 |
| ARRDC3 | arrestin domain containing 3 | 0.0202468 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | 0.0202353 |
| HLA-A | major histocompatibility complex, class I, A | 0.0201931 |
| SLC25A6 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6 | 0.0200215 |
| FLNA | filamin A, alpha | 0.0197816 |
| POTEF | POTE ankyrin domain family, member F | 0.0195609 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0194727 |
| INSIG2 | insulin induced gene 2 | 0.0191218 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0186966 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0186919 |
| NUP58 | nucleoporin 58 | 0.0185366 |
| ZNF395 | zinc finger protein 395 | 0.0184255 |
| RPS4X | ribosomal protein S4, X-linked | 0.0184055 |
| RPL31 | ribosomal protein L31 | 0.0182972 |
| TMSB10 | thymosin beta 10 | 0.0182741 |
| RPS19 | ribosomal protein S19 | 0.0182482 |
| CD109 | CD109 molecule | 0.0182004 |
| PCBP2 | poly(rC) binding protein 2 | 0.0181833 |
| S100A9 | S100 calcium binding protein A9 | 0.018157 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0180651 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0178289 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0177046 |
| RPS3 | ribosomal protein S3 | 0.0174414 |
| SP3 | Sp3 transcription factor | 0.0172879 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0170407 |
| RPL35 | ribosomal protein L35 | 0.0170263 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0170201 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0167555 |
| HDGF | hepatoma-derived growth factor | 0.0164569 |
| PPFIA4 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 | 0.0163832 |
| MCL1 | myeloid cell leukemia 1 | 0.0163745 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0163723 |
| VIM | vimentin | 0.0160874 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.0159885 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0158858 |
| RPL13A | ribosomal protein L13a | 0.0158028 |
| CBX3 | chromobox homolog 3 | 0.0157541 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0156122 |
| YBX1 | Y box binding protein 1 | 0.0155997 |
| NDUFA4 | NDUFA4, mitochondrial complex associated | 0.0155144 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0154569 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0152031 |
| RPL21 | ribosomal protein L21 | 0.0151221 |
| RPL36 | ribosomal protein L36 | 0.0150973 |
| HSPG2 | heparan sulfate proteoglycan 2 | 0.0150503 |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 | 0.0149912 |
| RPS20 | ribosomal protein S20 | 0.0148888 |
| EEF1D | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) | 0.0148401 |
| CLEC1B | C-type lectin domain family 1, member B | 0.0147947 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0147681 |
| DIAPH3 | diaphanous-related formin 3 | 0.0147631 |
| ZNF160 | zinc finger protein 160 | 0.0146281 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.336906 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.257122 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.148923 |
| KYNU | kynureninase | -0.14098 |
| EXT1 | exostosin glycosyltransferase 1 | -0.117365 |
| FNDC3B | fibronectin type III domain containing 3B | -0.11589 |
| COL6A3 | collagen, type VI, alpha 3 | -0.102654 |
| CANX | calnexin | -0.0900651 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.086554 |
| AHNAK | AHNAK nucleoprotein | -0.0791464 |
| CD44 | CD44 molecule (Indian blood group) | -0.075877 |
| ASPH | aspartate beta-hydroxylase | -0.0724651 |
| OSMR | oncostatin M receptor | -0.0710112 |
| LOX | lysyl oxidase | -0.069005 |
| VCL | vinculin | -0.0674204 |
| MAP1B | microtubule-associated protein 1B | -0.0594874 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0580748 |
| GLIS3 | GLIS family zinc finger 3 | -0.057962 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0577615 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0558317 |
| PHF14 | PHD finger protein 14 | -0.0517533 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0511091 |
| SQSTM1 | sequestosome 1 | -0.0480943 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0479886 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0476912 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0471732 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0455342 |
| VMP1 | vacuole membrane protein 1 | -0.0437224 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0427718 |
| TPM4 | tropomyosin 4 | -0.0427176 |
| INHBA | inhibin, beta A | -0.0422877 |
| TXNRD1 | thioredoxin reductase 1 | -0.0421975 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0418873 |
| MCTP2 | multiple C2 domains, transmembrane 2 | -0.041189 |
| NABP1 | nucleic acid binding protein 1 | -0.0410755 |
| SCFD2 | sec1 family domain containing 2 | -0.0408526 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0402256 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0402153 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0401711 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0392374 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0386311 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0382278 |
| TNNC1 | troponin C type 1 (slow) | -0.0380638 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0379997 |
| SPAG9 | sperm associated antigen 9 | -0.0377343 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0374552 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | -0.0370597 |
| LDHA | lactate dehydrogenase A | -0.0368247 |
| ATXN1 | ataxin 1 | -0.035916 |
| SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) | -0.0356525 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | -0.0355128 |
| CARS1 | cysteinyl-tRNA synthetase 1 | -0.0354591 |
| CREB5 | cAMP responsive element binding protein 5 | -0.0353733 |
| CLINT1 | clathrin interactor 1 | -0.0350742 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0349036 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.03476 |
| DST | dystonin | -0.0346052 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0345056 |
| SBF2 | SET binding factor 2 | -0.0344429 |
| TNS3 | tensin 3 | -0.0340205 |
| TMEM263 | transmembrane protein 263 | -0.0336761 |
| USP34 | ubiquitin specific peptidase 34 | -0.0332377 |
| PGK1 | phosphoglycerate kinase 1 | -0.0331784 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0331691 |
| STK17A | serine/threonine kinase 17a | -0.0326432 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0324325 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0323573 |
| ACTN1 | actinin, alpha 1 | -0.0319582 |
| EGR1 | early growth response 1 | -0.0316244 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0313 |
| TPTE | transmembrane phosphatase with tensin homology | -0.0312419 |
| LYPD6B | LY6/PLAUR domain containing 6B | -0.0311089 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0310186 |
| MB21D2 | Mab-21 domain containing 2 | -0.0309539 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0308613 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0305501 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0304874 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0304514 |
| FUS | FUS RNA binding protein | -0.0303622 |
| KDELR2 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 | -0.0303358 |
| LRRC49 | leucine rich repeat containing 49 | -0.0302275 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | -0.0298221 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0296522 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0295307 |
| NIBAN1 | niban apoptosis regulator 1 | -0.029434 |
| GPR173 | G protein-coupled receptor 173 | -0.02884 |
| DGKD | diacylglycerol kinase, delta 130kDa | -0.0287385 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0283799 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0282742 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0278773 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0276792 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0276556 |
| NUP214 | nucleoporin 214kDa | -0.0276425 |
| ATM | ATM serine/threonine kinase | -0.0275791 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0274202 |
| ATP13A3 | ATPase type 13A3 | -0.0274125 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0273699 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0273257 |
| PALLD | palladin, cytoskeletal associated protein | -0.0268263 |
| ACTN4 | actinin, alpha 4 | -0.0267537 |
