| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Abiraterone acetate perturbation in HEC-1-A cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Abiraterone acetate_HEC-1-A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PLEC | plectin | 0.0434174 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0390568 |
| HLA-C | major histocompatibility complex, class I, C | 0.038027 |
| FLNA | filamin A, alpha | 0.0351585 |
| MT2A | metallothionein 2A | 0.0341834 |
| PAX8 | paired box 8 | 0.0316038 |
| ANKRD10 | ankyrin repeat domain 10 | 0.0310964 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0279156 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0277047 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0258711 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0246418 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0212409 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.020364 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0199896 |
| RACK1 | receptor for activated C kinase 1 | 0.0193908 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0190333 |
| RASA2 | RAS p21 protein activator 2 | 0.0181843 |
| LOC112694756 | uncharaterized LOC112694756 | 0.017469 |
| RPL12 | ribosomal protein L12 | 0.0149593 |
| PDIA5 | protein disulfide isomerase family A, member 5 | 0.0148726 |
| ACTG1 | actin gamma 1 | 0.0142396 |
| RPL13A | ribosomal protein L13a | 0.0138682 |
| NEK6 | NIMA-related kinase 6 | 0.013425 |
| CTNNAL1 | catenin (cadherin-associated protein), alpha-like 1 | 0.0132487 |
| WDR45B | WD repeat domain 45B | 0.0116195 |
| CUL4A | cullin 4A | 0.0115616 |
| HDLBP | high density lipoprotein binding protein | 0.0115446 |
| RPL27 | ribosomal protein L27 | 0.011532 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0115217 |
| RASA3 | RAS p21 protein activator 3 | 0.0114354 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | 0.0113134 |
| TMEM245 | transmembrane protein 245 | 0.0113073 |
| CAPN1 | calpain 1, (mu/I) large subunit | 0.011211 |
| PRRC2A | proline-rich coiled-coil 2A | 0.0110748 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0109136 |
| ALS2CL | ALS2 C-terminal like | 0.0106491 |
| YEATS2 | YEATS domain containing 2 | 0.010536 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0105332 |
| SYT13 | synaptotagmin XIII | 0.0100291 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.00998136 |
| RPS12 | ribosomal protein S12 | 0.00976492 |
| FNBP1L | formin binding protein 1-like | 0.00933135 |
| IWS1 | IWS1 homolog (S. cerevisiae) | 0.00932422 |
| YJEFN3 | YjeF N-terminal domain containing 3 | 0.00932025 |
| RPL29 | ribosomal protein L29 | 0.00920709 |
| HMBOX1 | homeobox containing 1 | 0.00919709 |
| RPL14 | ribosomal protein L14 | 0.00910195 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.00903545 |
| VPS54 | vacuolar protein sorting 54 homolog (S. cerevisiae) | 0.00898882 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.00891427 |
| SLC33A1 | solute carrier family 33 (acetyl-CoA transporter), member 1 | 0.00889157 |
| RPL3 | ribosomal protein L3 | 0.00884221 |
| PGM3 | phosphoglucomutase 3 | 0.00872221 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | 0.00856683 |
| DNAJC25 | DnaJ (Hsp40) homolog, subfamily C , member 25 | 0.00852497 |
| DAPK1 | death-associated protein kinase 1 | 0.00851806 |
| IRS2 | insulin receptor substrate 2 | 0.00850765 |
| RPL41 | ribosomal protein L41 | 0.00846117 |
| TDRD7 | tudor domain containing 7 | 0.00845668 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.00840355 |
| RNF40 | ring finger protein 40, E3 ubiquitin protein ligase | 0.00838687 |
| PPP2R2C | protein phosphatase 2, regulatory subunit B, gamma | 0.0083308 |
| BLCAP | bladder cancer associated protein | 0.00832918 |
| HNF1B | HNF1 homeobox B | 0.0082901 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.00827155 |
| SIN3B | SIN3 transcription regulator family member B | 0.00820567 |
| CCDC93 | coiled-coil domain containing 93 | 0.00817823 |
| RANBP3 | RAN binding protein 3 | 0.00815195 |
| RPS4X | ribosomal protein S4, X-linked | 0.0081329 |
| CTIF | CBP80/20-dependent translation initiation factor | 0.00811923 |
| MZT1 | mitotic spindle organizing protein 1 | 0.0080797 |
| EEIG1 | estrogen-induced osteoclastogenesis regulator 1 | 0.00805632 |
| SRP72 | signal recognition particle 72kDa | 0.00801252 |
| BTBD10 | BTB (POZ) domain containing 10 | 0.00797665 |
| EPN2 | epsin 2 | 0.00788282 |
| NME2 | NME/NM23 nucleoside diphosphate kinase 2 | 0.00785551 |
| CRAMP1 | cramped chromatin regulator homolog 1 | 0.00763043 |
| CDYL | chromodomain protein, Y-like | 0.00762513 |
| ST6GALNAC5 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 | 0.0075983 |
| UBAP2L | ubiquitin associated protein 2-like | 0.00758907 |
| ANKRD27 | ankyrin repeat domain 27 (VPS9 domain) | 0.0075763 |
| MINK1 | misshapen-like kinase 1 | 0.00748247 |
| HELZ | helicase with zinc finger | 0.00747177 |
| KLF13 | Kruppel-like factor 13 | 0.00744887 |
| ZNF24 | zinc finger protein 24 | 0.00736651 |
| PLK2 | polo-like kinase 2 | 0.00734367 |
| RPL34 | ribosomal protein L34 | 0.0072858 |
| FLII | flightless I homolog (Drosophila) | 0.00726458 |
| UBE2O | ubiquitin-conjugating enzyme E2O | 0.00726232 |
| MYRIP | myosin VIIA and Rab interacting protein | 0.00725582 |
| CDK5RAP2 | CDK5 regulatory subunit associated protein 2 | 0.00725122 |
| SFXN1 | sideroflexin 1 | 0.0072425 |
| SAFB2 | scaffold attachment factor B2 | 0.00720387 |
| CNOT8 | CCR4-NOT transcription complex, subunit 8 | 0.00719098 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | 0.00717603 |
| NDEL1 | nudE neurodevelopment protein 1-like 1 | 0.0070919 |
| ADAMTS9 | ADAM metallopeptidase with thrombospondin type 1 motif, 9 | 0.0070652 |
| RPS7 | ribosomal protein S7 | 0.00705745 |
| CLTB | clathrin, light chain B | 0.00705383 |
| SBNO2 | strawberry notch homolog 2 (Drosophila) | 0.00693525 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.1478 |
| PKM | pyruvate kinase, muscle | -0.103522 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0977731 |
| PTMA | prothymosin, alpha | -0.0930874 |
| TXNRD1 | thioredoxin reductase 1 | -0.0891265 |
| TMSB10 | thymosin beta 10 | -0.0800973 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0798051 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0727682 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0669984 |
| ASPH | aspartate beta-hydroxylase | -0.0653536 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0632063 |
| RAD51B | RAD51 paralog B | -0.0564691 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0558582 |
| EGR1 | early growth response 1 | -0.0557936 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0543039 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0532477 |
| VMP1 | vacuole membrane protein 1 | -0.0529962 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0526546 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | -0.0520872 |
| SSH2 | slingshot protein phosphatase 2 | -0.051931 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0516259 |
| BPTF | bromodomain PHD finger transcription factor | -0.0509888 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0506564 |
| MACROD2 | MACRO domain containing 2 | -0.0490548 |
| WWOX | WW domain containing oxidoreductase | -0.048374 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.048076 |
| ENO1 | enolase 1, (alpha) | -0.0468635 |
| SETD5 | SET domain containing 5 | -0.0458054 |
| CCND1 | cyclin D1 | -0.0453119 |
| TPM4 | tropomyosin 4 | -0.0440064 |
| DARS1 | aspartyl-tRNA synthetase 1 | -0.0436636 |
| SVIL | supervillin | -0.0431491 |
| VCL | vinculin | -0.0430453 |
| SKAP2 | src kinase associated phosphoprotein 2 | -0.0412835 |
| MAP4 | microtubule-associated protein 4 | -0.0410536 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0409747 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0404966 |
| BBX | bobby sox homolog (Drosophila) | -0.0399173 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | -0.03891 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0384726 |
| LDHA | lactate dehydrogenase A | -0.0383699 |
| POTEF | POTE ankyrin domain family, member F | -0.0370145 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0362743 |
| PCBP2 | poly(rC) binding protein 2 | -0.0351542 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0349495 |
| DEK | DEK proto-oncogene | -0.0347718 |
| DSTN | destrin (actin depolymerizing factor) | -0.0347353 |
| RPS6 | ribosomal protein S6 | -0.0342963 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.034246 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0341607 |
| TPI1 | triosephosphate isomerase 1 | -0.0338733 |
| TAOK1 | TAO kinase 1 | -0.0338256 |
| RBM39 | RNA binding motif protein 39 | -0.0335841 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0335039 |
| PFN1 | profilin 1 | -0.0334341 |
| CBX3 | chromobox homolog 3 | -0.0327793 |
| RHEX | regulator of hemoglobinization and erythroid cell expansion | -0.0327408 |
| KRT7 | keratin 7, type II | -0.0326028 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0323117 |
| APP | amyloid beta (A4) precursor protein | -0.032035 |
| DIAPH1 | diaphanous-related formin 1 | -0.0315224 |
| RNF213 | ring finger protein 213 | -0.0314114 |
| FHIT | fragile histidine triad | -0.0313202 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0310464 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.0309277 |
| SMC1A | structural maintenance of chromosomes 1A | -0.0308712 |
| B2M | beta-2-microglobulin | -0.0307456 |
| EREG | epiregulin | -0.030743 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | -0.0305929 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0304716 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0303795 |
| FTL | ferritin, light polypeptide | -0.0303223 |
| USP34 | ubiquitin specific peptidase 34 | -0.0302589 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0301524 |
| ATXN1 | ataxin 1 | -0.0301135 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0300165 |
| EZR | ezrin | -0.0299872 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0298576 |
| TUSC3 | tumor suppressor candidate 3 | -0.0297419 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0296935 |
| MACC1 | metastasis associated in colon cancer 1 | -0.0295735 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0291472 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0286411 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0283165 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0282169 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0279668 |
| PHIP | pleckstrin homology domain interacting protein | -0.0277494 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | -0.0274421 |
| SEPTIN7 | septin 7 | -0.0273919 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | -0.0273889 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | -0.0273621 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0272906 |
| LAMA4 | laminin, alpha 4 | -0.0272578 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0269507 |
| SMYD3 | SET and MYND domain containing 3 | -0.0269485 |
| EMP1 | epithelial membrane protein 1 | -0.0267412 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0264115 |
| DIAPH3 | diaphanous-related formin 3 | -0.0263872 |
| RPL5 | ribosomal protein L5 | -0.0262506 |
| OSBPL10 | oxysterol binding protein-like 10 | -0.0261857 |
