| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Abiraterone acetate perturbation in HS-578T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Abiraterone acetate_HS-578T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.145916 |
| NDRG1 | N-myc downstream regulated 1 | 0.129165 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.09038 |
| MT2A | metallothionein 2A | 0.0674763 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0640514 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0507986 |
| RPL35A | ribosomal protein L35a | 0.0489142 |
| CADM1 | cell adhesion molecule 1 | 0.0445655 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0430638 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0429922 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0404831 |
| PLEC | plectin | 0.0403542 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0390791 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0390476 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.037427 |
| HLA-C | major histocompatibility complex, class I, C | 0.0372679 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.035971 |
| MRTFA | myocardin related transcription factor A | 0.0355995 |
| GOLGA4 | golgin A4 | 0.0352225 |
| TMSB10 | thymosin beta 10 | 0.0330684 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0330123 |
| VEGFA | vascular endothelial growth factor A | 0.0321423 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0318908 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0316847 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0303623 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0280548 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | 0.0276224 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0273499 |
| CD109 | CD109 molecule | 0.0255371 |
| FMNL2 | formin-like 2 | 0.0252595 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0251408 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0250881 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0249349 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0247347 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.0242123 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0239593 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0239441 |
| NAV2 | neuron navigator 2 | 0.0236558 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0233067 |
| RPL36 | ribosomal protein L36 | 0.0228601 |
| TMEM165 | transmembrane protein 165 | 0.0225181 |
| RPL23 | ribosomal protein L23 | 0.0217955 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0211872 |
| RPL37A | ribosomal protein L37a | 0.0211191 |
| RPS8 | ribosomal protein S8 | 0.020945 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.020168 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0198695 |
| RPL12 | ribosomal protein L12 | 0.0197013 |
| CABIN1 | calcineurin binding protein 1 | 0.0196219 |
| TFG | TRK-fused gene | 0.0194767 |
| RPS6 | ribosomal protein S6 | 0.01945 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0194053 |
| SPAG9 | sperm associated antigen 9 | 0.0193385 |
| CSPP1 | centrosome and spindle pole associated protein 1 | 0.0192811 |
| FAM168A | family with sequence similarity 168, member A | 0.0190582 |
| ATP13A3 | ATPase type 13A3 | 0.0190172 |
| RPS3 | ribosomal protein S3 | 0.0189984 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0185747 |
| CLINT1 | clathrin interactor 1 | 0.0185592 |
| RPL34 | ribosomal protein L34 | 0.0184364 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0181946 |
| RYK | receptor-like tyrosine kinase | 0.0181198 |
| WAC | WW domain containing adaptor with coiled-coil | 0.018103 |
| KDM4B | lysine (K)-specific demethylase 4B | 0.0180899 |
| ACTG1 | actin gamma 1 | 0.0178882 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0177799 |
| MRPS6 | mitochondrial ribosomal protein S6 | 0.0177584 |
| KIF1B | kinesin family member 1B | 0.0176382 |
| CCNY | cyclin Y | 0.0176175 |
| PRR16 | proline rich 16 | 0.0175943 |
| FTL | ferritin, light polypeptide | 0.0174047 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0170302 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0170286 |
| MTMR3 | myotubularin related protein 3 | 0.0169509 |
| PDIA5 | protein disulfide isomerase family A, member 5 | 0.0169094 |
| TBC1D23 | TBC1 domain family, member 23 | 0.0168862 |
| COL4A2 | collagen, type IV, alpha 2 | 0.0167429 |
| RPS19 | ribosomal protein S19 | 0.016547 |
| CLTC | clathrin, heavy chain (Hc) | 0.0164704 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0162905 |
| RPS14 | ribosomal protein S14 | 0.0161262 |
| KIRREL3 | kin of IRRE like 3 (Drosophila) | 0.0159602 |
| PDE10A | phosphodiesterase 10A | 0.0158874 |
| HIP1 | huntingtin interacting protein 1 | 0.0157473 |
| SAFB2 | scaffold attachment factor B2 | 0.015706 |
| NBAS | neuroblastoma amplified sequence | 0.0157047 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | 0.0155976 |
| TENT4A | terminal nucleotidyltransferase 4A | 0.0155953 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0155152 |
| USP3 | ubiquitin specific peptidase 3 | 0.0155047 |
| SEC22A | SEC22 vesicle trafficking protein homolog A (S. cerevisiae) | 0.0154235 |
| COL5A1 | collagen, type V, alpha 1 | 0.0152972 |
| THRAP3 | thyroid hormone receptor associated protein 3 | 0.0152579 |
| TMF1 | TATA element modulatory factor 1 | 0.0150316 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0148537 |
| PRRC2A | proline-rich coiled-coil 2A | 0.0147113 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0147098 |
| CCDC88A | coiled-coil domain containing 88A | 0.014635 |
| SESN2 | sestrin 2 | 0.0146098 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.0145158 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.238889 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.20401 |
| COL1A1 | collagen, type I, alpha 1 | -0.164898 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.148024 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.135679 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.118653 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.106977 |
| CD44 | CD44 molecule (Indian blood group) | -0.104838 |
| NKAIN3 | Na+/K+ transporting ATPase interacting 3 | -0.0933479 |
| TPM4 | tropomyosin 4 | -0.0803172 |
| ASPH | aspartate beta-hydroxylase | -0.0775269 |
| COL1A2 | collagen, type I, alpha 2 | -0.0768899 |
| CANX | calnexin | -0.066912 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0662018 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | -0.0640198 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0632123 |
| CLIC4 | chloride intracellular channel 4 | -0.0626173 |
| STC1 | stanniocalcin 1 | -0.0611513 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0578024 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0560232 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0554952 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0545859 |
| POSTN | periostin, osteoblast specific factor | -0.0504563 |
| IER3 | immediate early response 3 | -0.0502248 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0471551 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0469207 |
| INHBA | inhibin, beta A | -0.0462014 |
| IL6ST | interleukin 6 signal transducer | -0.0445462 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0436855 |
| VIM | vimentin | -0.043652 |
| IL6 | interleukin 6 | -0.0431161 |
| VCAN | versican | -0.0430952 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | -0.041525 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0400957 |
| RIGI | RNA sensor RIG-I | -0.038981 |
| NRP1 | neuropilin 1 | -0.0375899 |
| TPM1 | tropomyosin 1 (alpha) | -0.0371142 |
| LDHA | lactate dehydrogenase A | -0.0369783 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0367022 |
| OSMR | oncostatin M receptor | -0.0365366 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0356422 |
| GLIS3 | GLIS family zinc finger 3 | -0.0354862 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0344603 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0343842 |
| MX2 | MX dynamin-like GTPase 2 | -0.0336611 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0329064 |
| SMAD3 | SMAD family member 3 | -0.0324894 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0323037 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0321918 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | -0.0316367 |
| HAS2 | hyaluronan synthase 2 | -0.0315213 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0314919 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0314526 |
| MAP1B | microtubule-associated protein 1B | -0.0310882 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0306653 |
| PKM | pyruvate kinase, muscle | -0.0306459 |
| FAT1 | FAT atypical cadherin 1 | -0.0304098 |
| COL3A1 | collagen, type III, alpha 1 | -0.0301636 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | -0.0288919 |
| VMP1 | vacuole membrane protein 1 | -0.0288747 |
| PIEZO2 | piezo-type mechanosensitive ion channel component 2 | -0.0285649 |
| NREP | neuronal regeneration related protein | -0.02783 |
| LIPG | lipase, endothelial | -0.0273905 |
| ECE1 | endothelin converting enzyme 1 | -0.0270783 |
| EGR1 | early growth response 1 | -0.0263681 |
| PLSCR1 | phospholipid scramblase 1 | -0.0262791 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0262456 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0261345 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0260691 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0258896 |
| KIAA1217 | KIAA1217 | -0.0255758 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0252554 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | -0.0250226 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0248496 |
| FOXP1 | forkhead box P1 | -0.0246504 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0242323 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0241361 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0240489 |
| HLA-B | major histocompatibility complex, class I, B | -0.0232328 |
| TMSB4X | thymosin beta 4, X-linked | -0.0230215 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.0229789 |
| AHNAK | AHNAK nucleoprotein | -0.0227663 |
| ADAM12 | ADAM metallopeptidase domain 12 | -0.0226093 |
| CNTN5 | contactin 5 | -0.022608 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0225718 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0224025 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0223025 |
| IGFBP7 | insulin-like growth factor binding protein 7 | -0.0222705 |
| APP | amyloid beta (A4) precursor protein | -0.0222309 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0221069 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.022088 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0218751 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0218156 |
| GLIPR1 | GLI pathogenesis-related 1 | -0.0217663 |
| CCND1 | cyclin D1 | -0.0213744 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | -0.0212381 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0211673 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0208851 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0208133 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0206625 |
