| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Abiraterone acetate perturbation in HT-29 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Abiraterone acetate_HT-29 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ITPKC | inositol-trisphosphate 3-kinase C | 0.115593 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0815579 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.074806 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0715291 |
| TXNRD1 | thioredoxin reductase 1 | 0.057094 |
| EZR | ezrin | 0.0555983 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0549964 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.054824 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0530564 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0515651 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | 0.0486616 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.04485 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.0396092 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0394043 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0381165 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0380159 |
| CALR | calreticulin | 0.0375099 |
| GOLGB1 | golgin B1 | 0.0357754 |
| ACACA | acetyl-CoA carboxylase alpha | 0.0334825 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0324185 |
| RPL13A | ribosomal protein L13a | 0.0322203 |
| OGA | O-GlcNAcase | 0.0313249 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0312591 |
| HYOU1 | hypoxia up-regulated 1 | 0.0309562 |
| CANX | calnexin | 0.0309465 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0301316 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0292149 |
| XPO1 | exportin 1 | 0.0286464 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0283654 |
| ZC3H15 | zinc finger CCCH-type containing 15 | 0.0276902 |
| RPL5 | ribosomal protein L5 | 0.0272839 |
| MATR3 | matrin 3 | 0.0271029 |
| BRD2 | bromodomain containing 2 | 0.0264561 |
| FN1 | fibronectin 1 | 0.025728 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0256962 |
| UBXN7 | UBX domain protein 7 | 0.0254999 |
| ATF3 | activating transcription factor 3 | 0.0254325 |
| JUP | junction plakoglobin | 0.0254253 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.025349 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0249369 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.0247922 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0245915 |
| PLEC | plectin | 0.02433 |
| TRAPPC9 | trafficking protein particle complex 9 | 0.0241521 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0238519 |
| TPM3 | tropomyosin 3 | 0.0237714 |
| RPS19 | ribosomal protein S19 | 0.023506 |
| RBM33 | RNA binding motif protein 33 | 0.0234949 |
| YTHDC1 | YTH domain containing 1 | 0.023039 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.02277 |
| HOXB3 | homeobox B3 | 0.0226872 |
| CLDN4 | claudin 4 | 0.0222212 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0221471 |
| HMGB2 | high mobility group box 2 | 0.0220373 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0219115 |
| RPLP1 | ribosomal protein, large, P1 | 0.0218309 |
| ARL5B | ADP-ribosylation factor-like 5B | 0.0218052 |
| GATAD2B | GATA zinc finger domain containing 2B | 0.0216408 |
| KIDINS220 | kinase D-interacting substrate, 220kDa | 0.0215571 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0214924 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0211251 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0210278 |
| SSR1 | signal sequence receptor, alpha | 0.0208484 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0208029 |
| NDUFB9 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 9, 22kDa | 0.0206847 |
| TNRC6A | trinucleotide repeat containing 6A | 0.0205857 |
| NECTIN2 | nectin cell adhesion molecule 2 | 0.0205665 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0204164 |
| PHF20L1 | PHD finger protein 20-like 1 | 0.0202811 |
| OCLN | occludin | 0.0201692 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.0201647 |
| RPS13 | ribosomal protein S13 | 0.020133 |
| TOR1AIP2 | torsin A interacting protein 2 | 0.0200962 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.0200349 |
| XRN1 | 5'-3' exoribonuclease 1 | 0.0197756 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.019757 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0197277 |
| AFDN | afadin, adherens junction formation factor | 0.0196469 |
| SURF4 | surfeit 4 | 0.0192159 |
| ESRP1 | epithelial splicing regulatory protein 1 | 0.0190378 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0187633 |
| ANXA11 | annexin A11 | 0.0186983 |
| RAPGEF5 | Rap guanine nucleotide exchange factor (GEF) 5 | 0.0185318 |
| LMNA | lamin A/C | 0.0184675 |
| RFX3 | regulatory factor X, 3 (influences HLA class II expression) | 0.0183959 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.018395 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0183095 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0181893 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0180917 |
| MANBA | mannosidase, beta A, lysosomal | 0.0178702 |
| VPS13A | vacuolar protein sorting 13 homolog A (S. cerevisiae) | 0.0178606 |
| CNOT12 | CCR4-NOT transcription complex subunit 12 | 0.0178008 |
| SINHCAF | SIN3-HDAC complex associated factor | 0.0177444 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0177423 |
| RPL37A | ribosomal protein L37a | 0.0177367 |
| SUZ12 | SUZ12 polycomb repressive complex 2 subunit | 0.0175821 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.017497 |
| BPTF | bromodomain PHD finger transcription factor | 0.0174138 |
| TTC17 | tetratricopeptide repeat domain 17 | 0.0173659 |
| RPS12 | ribosomal protein S12 | 0.0173655 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FTH1 | ferritin, heavy polypeptide 1 | -0.151892 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.123299 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.098567 |
| PTMA | prothymosin, alpha | -0.0979471 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | -0.0901091 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0882958 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | -0.0829576 |
| LAMA4 | laminin, alpha 4 | -0.0782748 |
| NDRG1 | N-myc downstream regulated 1 | -0.0676555 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0667632 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.066656 |
| LYZ | lysozyme | -0.0655056 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0646334 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0646056 |
| LMO7 | LIM domain 7 | -0.0609063 |
| FRY | furry homolog (Drosophila) | -0.0586955 |
| SLC45A4 | solute carrier family 45, member 4 | -0.0553626 |
| SMAD3 | SMAD family member 3 | -0.054846 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0538165 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0519321 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.050568 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | -0.0492357 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.048652 |
| WASF2 | WAS protein family, member 2 | -0.0482262 |
| S100A10 | S100 calcium binding protein A10 | -0.0474586 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0447402 |
| TMSB10 | thymosin beta 10 | -0.0445265 |
| SEPTIN9 | septin 9 | -0.0444553 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0441632 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0440355 |
| PGK1 | phosphoglycerate kinase 1 | -0.0429366 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0424825 |
| KRT19 | keratin 19, type I | -0.0418238 |
| CTBP2 | C-terminal binding protein 2 | -0.0407474 |
| PIAS1 | protein inhibitor of activated STAT, 1 | -0.0406452 |
| MMP7 | matrix metallopeptidase 7 | -0.0400722 |
| DIAPH2 | diaphanous-related formin 2 | -0.0399469 |
| ACTN4 | actinin, alpha 4 | -0.039879 |
| ACTG1 | actin gamma 1 | -0.0388791 |
| KRT8 | keratin 8, type II | -0.0385735 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.038199 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0379772 |
| TMEM123 | transmembrane protein 123 | -0.0376518 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0374735 |
| FOXO1 | forkhead box O1 | -0.0370499 |
| TMEM65 | transmembrane protein 65 | -0.0360167 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.0352065 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.034852 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0336691 |
| LDHA | lactate dehydrogenase A | -0.0333882 |
| CD2AP | CD2-associated protein | -0.0332315 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0332214 |
| CAPN8 | calpain 8 | -0.0320248 |
| ABHD2 | abhydrolase domain containing 2 | -0.0320009 |
| ANXA2 | annexin A2 | -0.0314821 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0312982 |
| RPS24 | ribosomal protein S24 | -0.0312899 |
| WWC1 | WW and C2 domain containing 1 | -0.0309652 |
| FLNB | filamin B, beta | -0.0307793 |
| WNT2B | wingless-type MMTV integration site family, member 2B | -0.0305955 |
| RAB10 | RAB10, member RAS oncogene family | -0.0303203 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.0301099 |
| SULF2 | sulfatase 2 | -0.0297258 |
| PERP | PERP, TP53 apoptosis effector | -0.0296352 |
| HMGA1 | high mobility group AT-hook 1 | -0.028774 |
| PKM | pyruvate kinase, muscle | -0.0285788 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0282229 |
| PPARD | peroxisome proliferator-activated receptor delta | -0.0278198 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | -0.0277685 |
| PARD3 | par-3 family cell polarity regulator | -0.027702 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.027283 |
| MYH14 | myosin, heavy chain 14, non-muscle | -0.0270101 |
| RPLP0 | ribosomal protein, large, P0 | -0.0267467 |
| CA12 | carbonic anhydrase XII | -0.0266386 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.026262 |
| S100A6 | S100 calcium binding protein A6 | -0.026156 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | -0.0261043 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0260187 |
| CLTC | clathrin, heavy chain (Hc) | -0.025669 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0255971 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.0253367 |
| NTSR1 | neurotensin receptor 1 (high affinity) | -0.0253248 |
| PYGB | phosphorylase, glycogen; brain | -0.0251749 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.0246657 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0245307 |
| TJP2 | tight junction protein 2 | -0.0243178 |
| PCED1B | PC-esterase domain containing 1B | -0.0241604 |
| PRR5L | proline rich 5 like | -0.0240676 |
| ASPH | aspartate beta-hydroxylase | -0.0239869 |
| EPB41 | erythrocyte membrane protein band 4.1 | -0.023967 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0238974 |
| LPIN2 | lipin 2 | -0.0238519 |
| NTN4 | netrin 4 | -0.0234743 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | -0.0234612 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0234376 |
| PPARG | peroxisome proliferator-activated receptor gamma | -0.0232591 |
| ITGA6 | integrin, alpha 6 | -0.0232221 |
| DGKH | diacylglycerol kinase, eta | -0.0231262 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.0230391 |
| BCL2L1 | BCL2-like 1 | -0.0229605 |
