| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Abiraterone acetate perturbation in J82 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Abiraterone acetate_J82 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HLA-C | major histocompatibility complex, class I, C | 0.0510822 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0402423 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0204255 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0192379 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | 0.0148046 |
| ATP13A3 | ATPase type 13A3 | 0.0140226 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0114271 |
| PRRC2A | proline-rich coiled-coil 2A | 0.011205 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | 0.00989015 |
| MT2A | metallothionein 2A | 0.00947412 |
| SCFD2 | sec1 family domain containing 2 | 0.00881157 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.00843246 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.00811299 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.00777496 |
| ANKRD10 | ankyrin repeat domain 10 | 0.00768797 |
| FTL | ferritin, light polypeptide | 0.00746663 |
| COG6 | component of oligomeric golgi complex 6 | 0.00736327 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.00703425 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | 0.00685144 |
| BTBD10 | BTB (POZ) domain containing 10 | 0.00664247 |
| ODF2 | outer dense fiber of sperm tails 2 | 0.00644513 |
| DNAJC25 | DnaJ (Hsp40) homolog, subfamily C , member 25 | 0.00629945 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.00624961 |
| SUCO | SUN domain containing ossification factor | 0.00616558 |
| AP2M1 | adaptor-related protein complex 2, mu 1 subunit | 0.00603053 |
| NDEL1 | nudE neurodevelopment protein 1-like 1 | 0.00592989 |
| TTC14 | tetratricopeptide repeat domain 14 | 0.00590904 |
| RAB18 | RAB18, member RAS oncogene family | 0.00582583 |
| PCMT1 | protein-L-isoaspartate (D-aspartate) O-methyltransferase | 0.00567179 |
| GOLGA2 | golgin A2 | 0.00563173 |
| TMEM39A | transmembrane protein 39A | 0.00561509 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.00560944 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | 0.00558804 |
| MT1X | metallothionein 1X | 0.00534924 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.00531335 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | 0.00531334 |
| WDR43 | WD repeat domain 43 | 0.00514218 |
| GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | 0.00511782 |
| TMEM41B | transmembrane protein 41B | 0.00511657 |
| SPTY2D1 | SPT2, Suppressor of Ty, domain containing 1 (S. cerevisiae) | 0.005116 |
| HLA-A | major histocompatibility complex, class I, A | 0.00510844 |
| OSMR | oncostatin M receptor | 0.00509947 |
| AP1G1 | adaptor-related protein complex 1, gamma 1 subunit | 0.00508476 |
| TMED3 | transmembrane emp24 protein transport domain containing 3 | 0.00505958 |
| CPAP | centrosome assembly and centriole elongation protein | 0.00505565 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.00498899 |
| CEP95 | centrosomal protein 95kDa | 0.00495585 |
| OLR1 | oxidized low density lipoprotein (lectin-like) receptor 1 | 0.00493596 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.00491401 |
| GAK | cyclin G associated kinase | 0.00490046 |
| C6ORF62 | chromosome 6 open reading frame 62 | 0.0048554 |
| GOLT1B | golgi transport 1B | 0.00485148 |
| WRN | Werner syndrome, RecQ helicase-like | 0.00482051 |
| SEC22B | SEC22 vesicle trafficking protein homolog B (S. cerevisiae) (gene/pseudogene) | 0.00477299 |
| GOSR2 | golgi SNAP receptor complex member 2 | 0.00472015 |
| YKT6 | YKT6 v-SNARE homolog (S. cerevisiae) | 0.00470087 |
| GPR107 | G protein-coupled receptor 107 | 0.00469052 |
| EIF3M | eukaryotic translation initiation factor 3, subunit M | 0.0046875 |
| GPX4 | glutathione peroxidase 4 | 0.00467251 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | 0.00465829 |
| PGM3 | phosphoglucomutase 3 | 0.00462579 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.00461964 |
| SPTLC1 | serine palmitoyltransferase, long chain base subunit 1 | 0.00460486 |
| PNPLA8 | patatin-like phospholipase domain containing 8 | 0.0045482 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.00453113 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.00452189 |
| KIAA0319L | KIAA0319-like | 0.00450718 |
| B2M | beta-2-microglobulin | 0.00449977 |
| NUP58 | nucleoporin 58 | 0.00449342 |
| LUZP1 | leucine zipper protein 1 | 0.00445877 |
| AGFG1 | ArfGAP with FG repeats 1 | 0.00444973 |
| TIMM23B | translocase of inner mitochondrial membrane 23 homolog B (yeast) | 0.00442927 |
| SENP5 | SUMO1/sentrin specific peptidase 5 | 0.00441883 |
| SURF4 | surfeit 4 | 0.0044085 |
| GOLPH3 | golgi phosphoprotein 3 (coat-protein) | 0.00438684 |
| SKI | SKI proto-oncogene | 0.00437684 |
| DIS3 | DIS3 exosome endoribonuclease and 3'-5' exoribonuclease | 0.00437357 |
| MAPK8 | mitogen-activated protein kinase 8 | 0.00431829 |
| GCN1 | GCN1 activator of EIF2AK4 | 0.00430723 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.00430669 |
| DDX18 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 | 0.00426414 |
| NLRP1 | NLR family, pyrin domain containing 1 | 0.0042584 |
| TM9SF2 | transmembrane 9 superfamily member 2 | 0.00424933 |
| BLCAP | bladder cancer associated protein | 0.00421961 |
| KLHDC10 | kelch domain containing 10 | 0.00421614 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.00420216 |
| SERP1 | stress-associated endoplasmic reticulum protein 1 | 0.00419747 |
| CHFR | checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase | 0.00419608 |
| EVI5 | ecotropic viral integration site 5 | 0.00417631 |
| CREB1 | cAMP responsive element binding protein 1 | 0.00417263 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.00416104 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.00416054 |
| ZBTB43 | zinc finger and BTB domain containing 43 | 0.00415604 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.00413288 |
| TOMM5 | translocase of outer mitochondrial membrane 5 homolog (yeast) | 0.00407546 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.00406566 |
| SRPRA | SRP receptor subunit alpha | 0.00406002 |
| CMPK1 | cytidine monophosphate (UMP-CMP) kinase 1, cytosolic | 0.00403905 |
| GPR173 | G protein-coupled receptor 173 | 0.0040345 |
| NUCB2 | nucleobindin 2 | 0.00400437 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.171757 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.103312 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0994899 |
| NDRG1 | N-myc downstream regulated 1 | -0.0871178 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0820767 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0802035 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0712279 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0698832 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0695776 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0550589 |
| PHACTR1 | phosphatase and actin regulator 1 | -0.0548405 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0532033 |
| RAI14 | retinoic acid induced 14 | -0.0466514 |
| ASPH | aspartate beta-hydroxylase | -0.0458569 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0448154 |
| POTEF | POTE ankyrin domain family, member F | -0.0421615 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0401963 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0394627 |
| ENO1 | enolase 1, (alpha) | -0.0387383 |
| DTNA | dystrobrevin, alpha | -0.0366796 |
| VIM | vimentin | -0.0357208 |
| DEK | DEK proto-oncogene | -0.0350516 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0338719 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.033373 |
| NAV2 | neuron navigator 2 | -0.0313655 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0308846 |
| DST | dystonin | -0.0306783 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.029848 |
| LDHA | lactate dehydrogenase A | -0.029525 |
| PKM | pyruvate kinase, muscle | -0.0294415 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0282878 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0279561 |
| FLNB | filamin B, beta | -0.027503 |
| CANX | calnexin | -0.0270578 |
| TPM4 | tropomyosin 4 | -0.0264819 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0261456 |
| MAP4 | microtubule-associated protein 4 | -0.0259725 |
| MAP1B | microtubule-associated protein 1B | -0.0254636 |
| MMP12 | matrix metallopeptidase 12 | -0.0254416 |
| ANXA2 | annexin A2 | -0.0253287 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0251336 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0246537 |
| ADM | adrenomedullin | -0.0244314 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0243766 |
| PTMA | prothymosin, alpha | -0.0240206 |
| TPM1 | tropomyosin 1 (alpha) | -0.0239632 |
| PGK1 | phosphoglycerate kinase 1 | -0.0239146 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0237539 |
| PTK2 | protein tyrosine kinase 2 | -0.0232015 |
| RPS6 | ribosomal protein S6 | -0.0226413 |
| JUN | jun proto-oncogene | -0.0225843 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0224174 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0223311 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0222396 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0219812 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0217617 |
| PLCB4 | phospholipase C, beta 4 | -0.0217502 |
| CCND1 | cyclin D1 | -0.0216644 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0214942 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0212954 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0211962 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0210788 |
| COL5A1 | collagen, type V, alpha 1 | -0.0204989 |
| ACTG1 | actin gamma 1 | -0.0204514 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0201647 |
| SBF2 | SET binding factor 2 | -0.0197295 |
| PODXL | podocalyxin-like | -0.0197003 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0193427 |
| ERBIN | erbb2 interacting protein | -0.019047 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0190036 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0189403 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0188546 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0188442 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0185248 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0184304 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0181204 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0179688 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0179438 |
| PLIN2 | perilipin 2 | -0.0178689 |
| SLC12A8 | solute carrier family 12, member 8 | -0.0176735 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.0175512 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0174835 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | -0.0174511 |
| TMSB4X | thymosin beta 4, X-linked | -0.0170991 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0170537 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | -0.0170159 |
| EGFR | epidermal growth factor receptor | -0.0168767 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0168607 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0168594 |
| CCDC80 | coiled-coil domain containing 80 | -0.0167175 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0165791 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0165311 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.0165129 |
| RIGI | RNA sensor RIG-I | -0.0164738 |
| CCBE1 | collagen and calcium binding EGF domains 1 | -0.0162774 |
| VEGFA | vascular endothelial growth factor A | -0.0162567 |
| RND3 | Rho family GTPase 3 | -0.0162438 |
| RAD51B | RAD51 paralog B | -0.0162336 |
| NAV1 | neuron navigator 1 | -0.016132 |
| CUX1 | cut-like homeobox 1 | -0.0160754 |