| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Abiraterone acetate perturbation in LOX-IMVI cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Abiraterone acetate_LOX-IMVI drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DTNA | dystrobrevin, alpha | 0.178232 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0895218 |
| NUP58 | nucleoporin 58 | 0.0790979 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0597017 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0526797 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0502005 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0499849 |
| WDR45B | WD repeat domain 45B | 0.0480629 |
| WDR43 | WD repeat domain 43 | 0.047347 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0440373 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0423201 |
| ENKUR | enkurin, TRPC channel interacting protein | 0.0420787 |
| PRRC2A | proline-rich coiled-coil 2A | 0.0393233 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0368536 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0363701 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0363236 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | 0.0353878 |
| ACTG1 | actin gamma 1 | 0.0343966 |
| CORO1C | coronin, actin binding protein, 1C | 0.0340155 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0325967 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0316787 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0314659 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0308227 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0304861 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0301103 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0294109 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0292088 |
| ATP13A3 | ATPase type 13A3 | 0.0288918 |
| SPAG9 | sperm associated antigen 9 | 0.028869 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0280871 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | 0.0280623 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0278087 |
| RLF | rearranged L-myc fusion | 0.0275182 |
| RNF145 | ring finger protein 145 | 0.0267542 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0261689 |
| IRS2 | insulin receptor substrate 2 | 0.0261651 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0261213 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0258848 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | 0.0252939 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0252351 |
| CFAP251 | cilia and flagella associated protein 251 | 0.0252331 |
| APP | amyloid beta (A4) precursor protein | 0.0249623 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0245262 |
| USP36 | ubiquitin specific peptidase 36 | 0.0244622 |
| TLE4 | transducin-like enhancer of split 4 | 0.0244201 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0243899 |
| MALT1 | MALT1 paracaspase | 0.0236104 |
| RBM26 | RNA binding motif protein 26 | 0.0234879 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0234514 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0233605 |
| PAWR | PRKC, apoptosis, WT1, regulator | 0.0230697 |
| CASC3 | cancer susceptibility candidate 3 | 0.0228227 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0226493 |
| ANXA2 | annexin A2 | 0.0226287 |
| MAP4K3 | mitogen-activated protein kinase kinase kinase kinase 3 | 0.0226194 |
| CDC73 | cell division cycle 73 | 0.0226174 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0221621 |
| RASA2 | RAS p21 protein activator 2 | 0.0217908 |
| YTHDC1 | YTH domain containing 1 | 0.0217128 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | 0.0216114 |
| TFRC | transferrin receptor | 0.0215565 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0215115 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0214276 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.021067 |
| CUL3 | cullin 3 | 0.0209494 |
| USP15 | ubiquitin specific peptidase 15 | 0.020882 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0207976 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0207761 |
| SCAF8 | SR-related CTD-associated factor 8 | 0.0206024 |
| NUP153 | nucleoporin 153kDa | 0.0204513 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | 0.0203447 |
| MED13 | mediator complex subunit 13 | 0.0200584 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | 0.0199588 |
| YTHDF3 | YTH N(6)-methyladenosine RNA binding protein 3 | 0.0198973 |
| NCKAP1 | NCK-associated protein 1 | 0.0196994 |
| RBM33 | RNA binding motif protein 33 | 0.0196576 |
| USP3 | ubiquitin specific peptidase 3 | 0.0196429 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.019447 |
| HDAC3 | histone deacetylase 3 | 0.0193265 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.0192167 |
| TAF4B | TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa | 0.0191822 |
| CD109 | CD109 molecule | 0.019115 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0189372 |
| ETNK1 | ethanolamine kinase 1 | 0.0186255 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0185167 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0184994 |
| EPG5 | ectopic P-granules autophagy protein 5 homolog (C. elegans) | 0.0184433 |
| MIMS1 | mitochondrial inner membrane scaffold 1 | 0.0184274 |
| TRIM33 | tripartite motif containing 33 | 0.0183699 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | 0.0183126 |
| VEZT | vezatin, adherens junctions transmembrane protein | 0.0182384 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 | 0.0181008 |
| USP24 | ubiquitin specific peptidase 24 | 0.018086 |
| TFG | TRK-fused gene | 0.0180596 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | 0.0179893 |
| EIF3B | eukaryotic translation initiation factor 3, subunit B | 0.0179398 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.017651 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0176474 |
| SLC25A26 | solute carrier family 25 (S-adenosylmethionine carrier), member 26 | 0.0174811 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0173904 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.316502 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.218992 |
| GPC6 | glypican 6 | -0.122651 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.113154 |
| TMSB10 | thymosin beta 10 | -0.110696 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.108791 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.107803 |
| ASPH | aspartate beta-hydroxylase | -0.104277 |
| EGR1 | early growth response 1 | -0.0878873 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0773372 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0725147 |
| PTMA | prothymosin, alpha | -0.0704759 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0702554 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0690131 |
| RPS6 | ribosomal protein S6 | -0.0684197 |
| PKM | pyruvate kinase, muscle | -0.0681128 |
| POTEF | POTE ankyrin domain family, member F | -0.0663586 |
| CD44 | CD44 molecule (Indian blood group) | -0.0641386 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.0639004 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0632893 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0630522 |
| TPM4 | tropomyosin 4 | -0.0619564 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0602859 |
| CDH13 | cadherin 13 | -0.0597773 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.059522 |
| FOXP1 | forkhead box P1 | -0.0562919 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0553106 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.052176 |
| PHACTR1 | phosphatase and actin regulator 1 | -0.0506575 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0490951 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0486488 |
| RIGI | RNA sensor RIG-I | -0.0477454 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0473825 |
| SAMD3 | sterile alpha motif domain containing 3 | -0.0470647 |
| AHNAK | AHNAK nucleoprotein | -0.0467339 |
| LDHA | lactate dehydrogenase A | -0.0451092 |
| EFNA5 | ephrin-A5 | -0.0435417 |
| HMGA1 | high mobility group AT-hook 1 | -0.0433782 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0407196 |
| RNF213 | ring finger protein 213 | -0.0389084 |
| PTK2 | protein tyrosine kinase 2 | -0.0386884 |
| MMP12 | matrix metallopeptidase 12 | -0.0384686 |
| NAV1 | neuron navigator 1 | -0.0380405 |
| KIAA1217 | KIAA1217 | -0.0379594 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0378955 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0376512 |
| KIAA1549L | KIAA1549-like | -0.0375878 |
| HMGA2 | high mobility group AT-hook 2 | -0.0370488 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0360417 |
| TBC1D5 | TBC1 domain family, member 5 | -0.035865 |
| MAP1B | microtubule-associated protein 1B | -0.0358037 |
| CDK6 | cyclin-dependent kinase 6 | -0.0356752 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0355936 |
| MCL1 | myeloid cell leukemia 1 | -0.0347862 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0347702 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0341166 |
| ITGA6 | integrin, alpha 6 | -0.0340529 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0340042 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0334361 |
| ENO1 | enolase 1, (alpha) | -0.0331056 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0330391 |
| VCL | vinculin | -0.0327347 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0326635 |
| EMP1 | epithelial membrane protein 1 | -0.0325112 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.0320769 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | -0.0319636 |
| CTSB | cathepsin B | -0.0318852 |
| BPTF | bromodomain PHD finger transcription factor | -0.0318476 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0313425 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | -0.0312827 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0312017 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0311259 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0308556 |
| TNNC1 | troponin C type 1 (slow) | -0.0308168 |
| RPLP0 | ribosomal protein, large, P0 | -0.0307917 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.0303646 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0303207 |
| NRP2 | neuropilin 2 | -0.0303048 |
| JUN | jun proto-oncogene | -0.0302165 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0300608 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0298403 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0297244 |
| RAD51B | RAD51 paralog B | -0.0295743 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0295159 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0289309 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0287821 |
| RPS24 | ribosomal protein S24 | -0.0286419 |
| ATXN1 | ataxin 1 | -0.0284062 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0282953 |
| VCAN | versican | -0.028118 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0278574 |
| MSN | moesin | -0.027857 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0278538 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0276929 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | -0.0275469 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.027488 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0273974 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0272244 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.027059 |
| NTM | neurotrimin | -0.0268709 |
