| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Abiraterone acetate perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Abiraterone acetate_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LOC112694756 | uncharaterized LOC112694756 | 0.059538 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.059183 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0430444 |
| EREG | epiregulin | 0.040903 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.039716 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | 0.0386005 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0372531 |
| TNS4 | tensin 4 | 0.0345932 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0333581 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | 0.0322841 |
| GOLGA4 | golgin A4 | 0.0322549 |
| PLEC | plectin | 0.0315293 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0305204 |
| WDR45B | WD repeat domain 45B | 0.0299785 |
| NDRG1 | N-myc downstream regulated 1 | 0.0299342 |
| RPL3 | ribosomal protein L3 | 0.0285948 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0278344 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0275292 |
| KRT18 | keratin 18, type I | 0.0272831 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0267614 |
| FAM13A | family with sequence similarity 13, member A | 0.0243569 |
| RNF145 | ring finger protein 145 | 0.0240348 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.023154 |
| HDLBP | high density lipoprotein binding protein | 0.0228318 |
| OGA | O-GlcNAcase | 0.0225792 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0223105 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0220957 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.0216038 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0210946 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0208198 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0204459 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0203215 |
| RPS3 | ribosomal protein S3 | 0.0200797 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0198031 |
| S100P | S100 calcium binding protein P | 0.0196152 |
| CDH17 | cadherin 17, LI cadherin (liver-intestine) | 0.0194397 |
| ANKRD11 | ankyrin repeat domain 11 | 0.018927 |
| CALR | calreticulin | 0.0187915 |
| DERA | deoxyribose-phosphate aldolase (putative) | 0.0187475 |
| VEGFA | vascular endothelial growth factor A | 0.018639 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 | 0.0185628 |
| DSPP | dentin sialophosphoprotein | 0.0184338 |
| RNF43 | ring finger protein 43 | 0.0184176 |
| NUP58 | nucleoporin 58 | 0.0182437 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.018117 |
| GDF15 | growth differentiation factor 15 | 0.0179847 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.0177973 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0177072 |
| TPM3 | tropomyosin 3 | 0.0175645 |
| YBX1 | Y box binding protein 1 | 0.0171567 |
| LDHA | lactate dehydrogenase A | 0.0167201 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0166046 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0161253 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0160832 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0159287 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0156193 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.01515 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | 0.0151378 |
| TMF1 | TATA element modulatory factor 1 | 0.0148676 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | 0.014822 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0147226 |
| YTHDC1 | YTH domain containing 1 | 0.0147138 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0146858 |
| RBM39 | RNA binding motif protein 39 | 0.01465 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0146424 |
| RTN4 | reticulon 4 | 0.0146402 |
| TFG | TRK-fused gene | 0.0144795 |
| TXNRD1 | thioredoxin reductase 1 | 0.0144219 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | 0.0143568 |
| MED13L | mediator complex subunit 13-like | 0.014126 |
| PNN | pinin, desmosome associated protein | 0.014111 |
| SRP54 | signal recognition particle 54kDa | 0.0140665 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0138677 |
| ESRP1 | epithelial splicing regulatory protein 1 | 0.0136874 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0135344 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0133595 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0133435 |
| CLTC | clathrin, heavy chain (Hc) | 0.0130857 |
| RACK1 | receptor for activated C kinase 1 | 0.0129347 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0129099 |
| ARHGEF10L | Rho guanine nucleotide exchange factor (GEF) 10-like | 0.0126151 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0125748 |
| CUL3 | cullin 3 | 0.0125562 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0125079 |
| NARS1 | asparaginyl-tRNA synthetase 1 | 0.0124051 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | 0.0124043 |
| SCARB2 | scavenger receptor class B, member 2 | 0.0123006 |
| RPL13A | ribosomal protein L13a | 0.0122431 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0122371 |
| GOLGA2 | golgin A2 | 0.0121528 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0120897 |
| AFDN | afadin, adherens junction formation factor | 0.0120411 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0119771 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.0119486 |
| CDK5RAP3 | CDK5 regulatory subunit associated protein 3 | 0.011823 |
| GSTP1 | glutathione S-transferase pi 1 | 0.011745 |
| XPOT | exportin, tRNA | 0.0116192 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0115953 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0115852 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0115836 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NPSR1 | neuropeptide S receptor 1 | -0.185359 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.124305 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.112074 |
| MYO1E | myosin IE | -0.0872913 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0856533 |
| PTMA | prothymosin, alpha | -0.0848918 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0822203 |
| TMSB10 | thymosin beta 10 | -0.0782662 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0765043 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0726155 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0663432 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0633715 |
| VCL | vinculin | -0.062921 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0606352 |
| GREB1L | growth regulation by estrogen in breast cancer-like | -0.0584499 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0574788 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0556239 |
| GPHN | gephyrin | -0.0552807 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | -0.0483508 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0477346 |
| RPS6 | ribosomal protein S6 | -0.0470892 |
| AHNAK | AHNAK nucleoprotein | -0.0440141 |
| FHIT | fragile histidine triad | -0.0437734 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0432792 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0431691 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0398215 |
| SMYD3 | SET and MYND domain containing 3 | -0.0396647 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0389214 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.038636 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0369929 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0368398 |
| PDLIM5 | PDZ and LIM domain 5 | -0.036836 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0367395 |
| RNF217 | ring finger protein 217 | -0.0353612 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0334739 |
| TPM4 | tropomyosin 4 | -0.033101 |
| SAMD5 | sterile alpha motif domain containing 5 | -0.032681 |
| ONECUT3 | one cut homeobox 3 | -0.0326675 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0326173 |
| DIAPH2 | diaphanous-related formin 2 | -0.0321909 |
| FRMD5 | FERM domain containing 5 | -0.0316246 |
| RAD51B | RAD51 paralog B | -0.0314702 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0305517 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0302117 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0299063 |
| EGFR | epidermal growth factor receptor | -0.0289818 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0286749 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0278666 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0276565 |
| FOXP1 | forkhead box P1 | -0.0269914 |
| PARD3 | par-3 family cell polarity regulator | -0.0266589 |
| RPS24 | ribosomal protein S24 | -0.0261241 |
| CADPS | Ca++-dependent secretion activator | -0.026084 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0259536 |
| SH3D19 | SH3 domain containing 19 | -0.0257355 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0251663 |
| TFF1 | trefoil factor 1 | -0.0251247 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | -0.0250425 |
| LAMA4 | laminin, alpha 4 | -0.0248183 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | -0.0247378 |
| CALB1 | calbindin 1, 28kDa | -0.0246633 |
| MECOM | MDS1 and EVI1 complex locus | -0.0245813 |
| PALLD | palladin, cytoskeletal associated protein | -0.0242143 |
| RPS8 | ribosomal protein S8 | -0.0241608 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0240052 |
| CUX1 | cut-like homeobox 1 | -0.0238408 |
| PTPRB | protein tyrosine phosphatase, receptor type, B | -0.0238334 |
| NRXN3 | neurexin 3 | -0.0236483 |
| S100A10 | S100 calcium binding protein A10 | -0.0236293 |
| B4GALNT3 | beta-1,4-N-acetyl-galactosaminyl transferase 3 | -0.023508 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0232003 |
| DLGAP1 | discs, large (Drosophila) homolog-associated protein 1 | -0.0227755 |
| PCDH9 | protocadherin 9 | -0.0227662 |
| FBXO11 | F-box protein 11 | -0.022349 |
| POF1B | premature ovarian failure, 1B | -0.0217358 |
| EHBP1 | EH domain binding protein 1 | -0.0213605 |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide | -0.0213182 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0213064 |
| MYO1D | myosin ID | -0.0212574 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0212474 |
| PARD3B | par-3 family cell polarity regulator beta | -0.0212086 |
| RPS25 | ribosomal protein S25 | -0.021091 |
| DENND1A | DENN/MADD domain containing 1A | -0.0207195 |
| EXOC4 | exocyst complex component 4 | -0.0206177 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | -0.0205591 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.020338 |
| CCND1 | cyclin D1 | -0.0203199 |
| RIN2 | Ras and Rab interactor 2 | -0.0202923 |
| JMJD1C | jumonji domain containing 1C | -0.0200822 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0198719 |
| ACTG1 | actin gamma 1 | -0.0198403 |
| RPS23 | ribosomal protein S23 | -0.0197821 |
| CCDC91 | coiled-coil domain containing 91 | -0.0195465 |
| ARHGAP6 | Rho GTPase activating protein 6 | -0.0193374 |
| ASPH | aspartate beta-hydroxylase | -0.0191319 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) | -0.0191167 |
| PPARG | peroxisome proliferator-activated receptor gamma | -0.0190768 |
| AHCYL2 | adenosylhomocysteinase-like 2 | -0.0190454 |
| HMGB1 | high mobility group box 1 | -0.01904 |
| LSAMP | limbic system-associated membrane protein | -0.0188625 |
