| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Abiraterone acetate perturbation in LoVo cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Abiraterone acetate_LoVo drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ACTG1 | actin gamma 1 | 0.0597086 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0535571 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0500348 |
| RPL35A | ribosomal protein L35a | 0.0463802 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.041841 |
| GOLGA4 | golgin A4 | 0.0398942 |
| RPL13A | ribosomal protein L13a | 0.0393056 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0376327 |
| RPS6 | ribosomal protein S6 | 0.0351646 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0350623 |
| HDLBP | high density lipoprotein binding protein | 0.0323372 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0315334 |
| RPL3 | ribosomal protein L3 | 0.0313607 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0307745 |
| RACK1 | receptor for activated C kinase 1 | 0.029942 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0298852 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0298727 |
| SLC25A6 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6 | 0.0291256 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0283168 |
| ASS1 | argininosuccinate synthase 1 | 0.0265291 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0255358 |
| RPL11 | ribosomal protein L11 | 0.0244409 |
| MLEC | malectin | 0.0234208 |
| CALB1 | calbindin 1, 28kDa | 0.022576 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0225452 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0222438 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0217412 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0212088 |
| NDRG1 | N-myc downstream regulated 1 | 0.0211182 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0209782 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0208534 |
| GDF15 | growth differentiation factor 15 | 0.0206534 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0195884 |
| MT2A | metallothionein 2A | 0.0193541 |
| RPL12 | ribosomal protein L12 | 0.0192621 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0190882 |
| RPS19 | ribosomal protein S19 | 0.0189424 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | 0.0188255 |
| CYP2S1 | cytochrome P450, family 2, subfamily S, polypeptide 1 | 0.0187886 |
| RPL34 | ribosomal protein L34 | 0.018525 |
| RPS14 | ribosomal protein S14 | 0.0184268 |
| MORF4L2 | mortality factor 4 like 2 | 0.0183615 |
| CLINT1 | clathrin interactor 1 | 0.0176721 |
| TMF1 | TATA element modulatory factor 1 | 0.0173488 |
| DNM2 | dynamin 2 | 0.0172495 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0170376 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0170213 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0169273 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.016874 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.0168737 |
| SRP54 | signal recognition particle 54kDa | 0.016865 |
| HLA-C | major histocompatibility complex, class I, C | 0.0168393 |
| S100A14 | S100 calcium binding protein A14 | 0.0166701 |
| RPS20 | ribosomal protein S20 | 0.0165627 |
| PLAC8 | placenta-specific 8 | 0.0164915 |
| TMED2 | transmembrane emp24 domain trafficking protein 2 | 0.0162965 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.0162108 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 0.0157875 |
| RPLP1 | ribosomal protein, large, P1 | 0.0157856 |
| RPL37 | ribosomal protein L37 | 0.0156658 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0156065 |
| RPL29 | ribosomal protein L29 | 0.0154936 |
| VEGFA | vascular endothelial growth factor A | 0.0153696 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0152172 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.015198 |
| RPS2 | ribosomal protein S2 | 0.0151793 |
| TMSB10 | thymosin beta 10 | 0.0150068 |
| FTL | ferritin, light polypeptide | 0.0149682 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | 0.0149411 |
| RPS3 | ribosomal protein S3 | 0.0149349 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0147907 |
| CSTPP1 | centriolar satellite-associated tubulin polyglutamylase complex regulator 1 | 0.0147138 |
| LMNA | lamin A/C | 0.0146226 |
| ARRDC3 | arrestin domain containing 3 | 0.0145832 |
| KIF5B | kinesin family member 5B | 0.0145218 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0144126 |
| RPL27A | ribosomal protein L27a | 0.0142946 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | 0.014278 |
| RPL27 | ribosomal protein L27 | 0.0142727 |
| SEC24A | SEC24 family member A | 0.0142613 |
| TINAGL1 | tubulointerstitial nephritis antigen-like 1 | 0.0142491 |
| DYNC2I1 | dynein 2 intermediate chain 1 | 0.0141977 |
| AFDN | afadin, adherens junction formation factor | 0.0138249 |
| GOLGA2 | golgin A2 | 0.0135591 |
| PYGB | phosphorylase, glycogen; brain | 0.0135069 |
| RBCK1 | RanBP-type and C3HC4-type zinc finger containing 1 | 0.0134229 |
| JMY | junction mediating and regulatory protein, p53 cofactor | 0.0134196 |
| RPL36 | ribosomal protein L36 | 0.0134174 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0133476 |
| TMEM165 | transmembrane protein 165 | 0.0127881 |
| BRD2 | bromodomain containing 2 | 0.0127473 |
| YBX1 | Y box binding protein 1 | 0.012712 |
| LRRC1 | leucine rich repeat containing 1 | 0.0124545 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0123436 |
| SAFB2 | scaffold attachment factor B2 | 0.0122296 |
| MSI2 | musashi RNA-binding protein 2 | 0.0121159 |
| HMGA1 | high mobility group AT-hook 1 | 0.011953 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0119418 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | 0.0117889 |
| SFXN1 | sideroflexin 1 | 0.0116182 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.134082 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.126056 |
| LMO7 | LIM domain 7 | -0.124734 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.116309 |
| UBC | ubiquitin C | -0.102575 |
| RPS27A | ribosomal protein S27a | -0.0974244 |
| MYO1E | myosin IE | -0.0943537 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0858964 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0675245 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0663278 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0651876 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0626635 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0594402 |
| RIMKLB | ribosomal modification protein rimK-like family member B | -0.056859 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0567785 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0563802 |
| FOXO1 | forkhead box O1 | -0.0517468 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | -0.050928 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0506971 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0504245 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0503011 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.048167 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0473671 |
| PTMA | prothymosin, alpha | -0.046655 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0454816 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0445299 |
| RIGI | RNA sensor RIG-I | -0.0443734 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0430654 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0430106 |
| PRSS3 | protease, serine, 3 | -0.0430022 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0426889 |
| ITPRID2 | ITPR interacting domain containing 2 | -0.0425241 |
| PKP2 | plakophilin 2 | -0.0416955 |
| KRT8 | keratin 8, type II | -0.04158 |
| SERINC5 | serine incorporator 5 | -0.0412956 |
| FOXP1 | forkhead box P1 | -0.0409646 |
| MX1 | MX dynamin-like GTPase 1 | -0.0401858 |
| PCBP2 | poly(rC) binding protein 2 | -0.0392816 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0391686 |
| MUC13 | mucin 13, cell surface associated | -0.0387553 |
| ITGA6 | integrin, alpha 6 | -0.0380005 |
| SP100 | SP100 nuclear antigen | -0.0374257 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -0.0368696 |
| SMYD3 | SET and MYND domain containing 3 | -0.036354 |
| PARD3B | par-3 family cell polarity regulator beta | -0.0353462 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0347097 |
| ASPH | aspartate beta-hydroxylase | -0.034616 |
| SLC38A2 | solute carrier family 38, member 2 | -0.034557 |
| SFPQ | splicing factor proline/glutamine-rich | -0.0339692 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0338381 |
| PKM | pyruvate kinase, muscle | -0.0333071 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | -0.032979 |
| RPS24 | ribosomal protein S24 | -0.0329261 |
| RPLP2 | ribosomal protein, large, P2 | -0.0328569 |
| TCF12 | transcription factor 12 | -0.0328309 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.032776 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0326858 |
| EREG | epiregulin | -0.0323357 |
| SPON1 | spondin 1, extracellular matrix protein | -0.0321463 |
| VCL | vinculin | -0.0321363 |
| DSG3 | desmoglein 3 | -0.0319029 |
| ETV6 | ets variant 6 | -0.0317548 |
| RNF213 | ring finger protein 213 | -0.0312913 |
| AHCYL2 | adenosylhomocysteinase-like 2 | -0.0312482 |
| PLEKHG1 | pleckstrin homology domain containing, family G (with RhoGef domain) member 1 | -0.0310928 |
| HLA-B | major histocompatibility complex, class I, B | -0.0308538 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0306009 |
| RPS23 | ribosomal protein S23 | -0.0304742 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0303184 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0302528 |
| FRMD5 | FERM domain containing 5 | -0.0301721 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0298643 |
| AREG | amphiregulin | -0.0295374 |
| ATXN1 | ataxin 1 | -0.0295018 |
| AHNAK | AHNAK nucleoprotein | -0.0294488 |
| TNFAIP8 | tumor necrosis factor, alpha-induced protein 8 | -0.0293085 |
| MX2 | MX dynamin-like GTPase 2 | -0.0292204 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0290964 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | -0.0289118 |
| FBXO11 | F-box protein 11 | -0.0286116 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0283984 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0283843 |
| RPL4 | ribosomal protein L4 | -0.0279781 |
| TSPAN8 | tetraspanin 8 | -0.0277522 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.027673 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0275054 |
| ARL15 | ADP-ribosylation factor-like 15 | -0.0273658 |
| MYO1D | myosin ID | -0.0269995 |
| WWC1 | WW and C2 domain containing 1 | -0.0268905 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0265883 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0265583 |
| ABHD17C | abhydrolase domain containing 17C | -0.02631 |
| TNRC18 | trinucleotide repeat containing 18 | -0.0262343 |
| FER | fer (fps/fes related) tyrosine kinase | -0.0262114 |
| VMP1 | vacuole membrane protein 1 | -0.0261277 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0260117 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0259028 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | -0.0257389 |
| TRIM2 | tripartite motif containing 2 | -0.0255483 |
| EGFR | epidermal growth factor receptor | -0.0250802 |