| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Abiraterone acetate perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Abiraterone acetate_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EEF2 | eukaryotic translation elongation factor 2 | 0.0689715 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0561504 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0331174 |
| TPM3 | tropomyosin 3 | 0.032517 |
| MCL1 | myeloid cell leukemia 1 | 0.0313109 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0306625 |
| PCBP2 | poly(rC) binding protein 2 | 0.0306048 |
| RPL3 | ribosomal protein L3 | 0.0302124 |
| SET | SET nuclear proto-oncogene | 0.029755 |
| PLEC | plectin | 0.0293472 |
| MSN | moesin | 0.0269062 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.026319 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0257714 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0254352 |
| FOSL1 | FOS-like antigen 1 | 0.0245703 |
| ARRDC3 | arrestin domain containing 3 | 0.0241131 |
| PRRC2A | proline-rich coiled-coil 2A | 0.023553 |
| NUP58 | nucleoporin 58 | 0.0221091 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0218716 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | 0.0211415 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0200551 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0197999 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0192625 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0184767 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0184575 |
| VEGFA | vascular endothelial growth factor A | 0.0184049 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0178177 |
| RTN4 | reticulon 4 | 0.0178023 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.01773 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0175705 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0169923 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0167499 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.016181 |
| XPO1 | exportin 1 | 0.0161656 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0161182 |
| MATR3 | matrin 3 | 0.0159568 |
| MIDEAS | mitotic deacetylase associated SANT domain protein | 0.0159224 |
| POTEF | POTE ankyrin domain family, member F | 0.0158574 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0157387 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0156218 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0155786 |
| HDGF | hepatoma-derived growth factor | 0.0155523 |
| HYOU1 | hypoxia up-regulated 1 | 0.01537 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0152487 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.0152408 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0151816 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0150376 |
| CEP250 | centrosomal protein 250kDa | 0.0150356 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0147784 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0146851 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 0.0141721 |
| TNFRSF6B | tumor necrosis factor receptor superfamily, member 6b, decoy | 0.0141572 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.01406 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0138233 |
| SPIRE1 | spire-type actin nucleation factor 1 | 0.013622 |
| YBX1 | Y box binding protein 1 | 0.0136008 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.0135485 |
| SESN2 | sestrin 2 | 0.0134222 |
| ZNF148 | zinc finger protein 148 | 0.0134156 |
| SLK | STE20-like kinase | 0.0133139 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0132547 |
| SP3 | Sp3 transcription factor | 0.0130071 |
| HLA-C | major histocompatibility complex, class I, C | 0.0130048 |
| BEGAIN | brain-enriched guanylate kinase-associated | 0.012893 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0126104 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0125822 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0125575 |
| AP2M1 | adaptor-related protein complex 2, mu 1 subunit | 0.012526 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0124416 |
| NDRG1 | N-myc downstream regulated 1 | 0.0124341 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.0123674 |
| YEATS2 | YEATS domain containing 2 | 0.0122761 |
| AK2 | adenylate kinase 2 | 0.0122298 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0120118 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0118134 |
| XPO6 | exportin 6 | 0.0117744 |
| SZRD1 | SUZ RNA binding domain containing 1 | 0.0116797 |
| FAM120A | family with sequence similarity 120A | 0.0116653 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0116286 |
| PNN | pinin, desmosome associated protein | 0.0116086 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | 0.0115932 |
| WDR43 | WD repeat domain 43 | 0.0115893 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0115511 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | 0.0113906 |
| SLC25A6 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6 | 0.0113317 |
| RHOA | ras homolog family member A | 0.0111966 |
| PGM3 | phosphoglucomutase 3 | 0.011129 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0110384 |
| DDX41 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 41 | 0.0108504 |
| NARS1 | asparaginyl-tRNA synthetase 1 | 0.0108439 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | 0.0106874 |
| POM121 | POM121 transmembrane nucleoporin | 0.0105948 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0105737 |
| BRD2 | bromodomain containing 2 | 0.0105595 |
| NONO | non-POU domain containing, octamer-binding | 0.010456 |
| ARHGEF2 | Rho/Rac guanine nucleotide exchange factor (GEF) 2 | 0.010454 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0102333 |
| CABIN1 | calcineurin binding protein 1 | 0.0102178 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | 0.010174 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0100993 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.468533 |
| VIM | vimentin | -0.163637 |
| TP63 | tumor protein p63 | -0.135108 |
| CD44 | CD44 molecule (Indian blood group) | -0.134693 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.105948 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0933571 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0933463 |
| TMSB10 | thymosin beta 10 | -0.0841286 |
| PTMA | prothymosin, alpha | -0.0795596 |
| RUNX1 | runt-related transcription factor 1 | -0.0729787 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0721585 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0707759 |
| EHBP1 | EH domain binding protein 1 | -0.0637267 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0626759 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0619089 |
| DST | dystonin | -0.0598918 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0569375 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0550873 |
| MT2A | metallothionein 2A | -0.0547695 |
| HLA-B | major histocompatibility complex, class I, B | -0.0542834 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0523214 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.052039 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0519992 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0513911 |
| AHNAK | AHNAK nucleoprotein | -0.0513754 |
| SP100 | SP100 nuclear antigen | -0.0504437 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0486668 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0466363 |
| RIGI | RNA sensor RIG-I | -0.0458158 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0412523 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0401914 |
| PGK1 | phosphoglycerate kinase 1 | -0.0399184 |
| GCLM | glutamate-cysteine ligase, modifier subunit | -0.0399084 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0397259 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0387029 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0381184 |
| CANX | calnexin | -0.0377607 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.036278 |
| TXNRD1 | thioredoxin reductase 1 | -0.0350072 |
| EPHA4 | EPH receptor A4 | -0.034675 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0335692 |
| ZNF217 | zinc finger protein 217 | -0.0333373 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0332967 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0331721 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0325819 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0323568 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0320241 |
| USP34 | ubiquitin specific peptidase 34 | -0.0318504 |
| APP | amyloid beta (A4) precursor protein | -0.0312511 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0304556 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0300532 |
| CMIP | c-Maf inducing protein | -0.0299523 |
| VMP1 | vacuole membrane protein 1 | -0.0299428 |
| RPS24 | ribosomal protein S24 | -0.0298261 |
| HDAC9 | histone deacetylase 9 | -0.0296259 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 | -0.0293945 |
| ACTG1 | actin gamma 1 | -0.0293106 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.02916 |
| SMYD3 | SET and MYND domain containing 3 | -0.029038 |
| PLSCR1 | phospholipid scramblase 1 | -0.0289128 |
| RPL12 | ribosomal protein L12 | -0.0286276 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0281602 |
| RPS8 | ribosomal protein S8 | -0.0278536 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0276344 |
| RAB7A | RAB7A, member RAS oncogene family | -0.027487 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0271094 |
| TSC22D1 | TSC22 domain family, member 1 | -0.0270349 |
| FMNL2 | formin-like 2 | -0.0269225 |
| CFAP299 | cilia and flagella associated protein 299 | -0.026787 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0261597 |
| FBXO11 | F-box protein 11 | -0.0261121 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0261014 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0259937 |
| VCL | vinculin | -0.0259171 |
| RPL36A | ribosomal protein L36a | -0.0258494 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | -0.0256986 |
| EMP1 | epithelial membrane protein 1 | -0.0255443 |
| RPS6 | ribosomal protein S6 | -0.0254394 |
| NF1 | neurofibromin 1 | -0.0250181 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | -0.0246054 |
| LDHA | lactate dehydrogenase A | -0.0244165 |
| EREG | epiregulin | -0.0240284 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.023812 |
| FUS | FUS RNA binding protein | -0.023773 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.023767 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0236729 |
| RPS23 | ribosomal protein S23 | -0.0235761 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0234464 |
| SRGN | serglycin | -0.0233829 |
| STK17A | serine/threonine kinase 17a | -0.0232791 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0232195 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | -0.0231563 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0230038 |
| PMP22 | peripheral myelin protein 22 | -0.0226705 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0226607 |
| RPL19 | ribosomal protein L19 | -0.0226283 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.022603 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | -0.0225953 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0225681 |
| RPL28 | ribosomal protein L28 | -0.022534 |
