| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Abiraterone acetate perturbation in NCI-H1573 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Abiraterone acetate_NCI-H1573 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NDRG1 | N-myc downstream regulated 1 | 0.105073 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0910963 |
| ARRDC3 | arrestin domain containing 3 | 0.050525 |
| FAM13A | family with sequence similarity 13, member A | 0.0498234 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0479218 |
| PLEC | plectin | 0.0352599 |
| SMAD3 | SMAD family member 3 | 0.0328038 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0324896 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0322937 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0280607 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0260004 |
| LAMB3 | laminin, beta 3 | 0.0257471 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0234833 |
| CES1 | carboxylesterase 1 | 0.0227538 |
| LRP1B | low density lipoprotein receptor-related protein 1B | 0.022128 |
| EGR1 | early growth response 1 | 0.0201093 |
| CCNL1 | cyclin L1 | 0.0200317 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | 0.0200264 |
| PDE8A | phosphodiesterase 8A | 0.0200248 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0199585 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | 0.0197194 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0195132 |
| KCMF1 | potassium channel modulatory factor 1 | 0.0190981 |
| SMTN | smoothelin | 0.0190376 |
| NGLY1 | N-glycanase 1 | 0.0178669 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0174467 |
| VOPP1 | vesicular, overexpressed in cancer, prosurvival protein 1 | 0.0173831 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0162435 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.01566 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.0154036 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.015259 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0151138 |
| WDR45B | WD repeat domain 45B | 0.01453 |
| NPTN | neuroplastin | 0.0140053 |
| BCL9L | B-cell CLL/lymphoma 9-like | 0.0140049 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0139868 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | 0.0138969 |
| PHF21A | PHD finger protein 21A | 0.013615 |
| HELZ | helicase with zinc finger | 0.0136125 |
| LMO7 | LIM domain 7 | 0.0135353 |
| MIDEAS | mitotic deacetylase associated SANT domain protein | 0.0134848 |
| ADGRF1 | adhesion G protein-coupled receptor F1 | 0.0132784 |
| IFNGR2 | interferon gamma receptor 2 (interferon gamma transducer 1) | 0.0130653 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0128678 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0127696 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0127427 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0126373 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0124701 |
| MSN | moesin | 0.012407 |
| ARL8B | ADP-ribosylation factor-like 8B | 0.0122273 |
| RIN2 | Ras and Rab interactor 2 | 0.0120687 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0120063 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0119541 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0116964 |
| PER1 | period circadian clock 1 | 0.0114849 |
| LAMA5 | laminin, alpha 5 | 0.0114136 |
| UBE2O | ubiquitin-conjugating enzyme E2O | 0.0113199 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0112835 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0112815 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0110494 |
| VEGFA | vascular endothelial growth factor A | 0.0106858 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0106351 |
| ANXA1 | annexin A1 | 0.0105977 |
| STC2 | stanniocalcin 2 | 0.0104458 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0104068 |
| RUNX1 | runt-related transcription factor 1 | 0.0101235 |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit | 0.0100901 |
| FAM117B | family with sequence similarity 117, member B | 0.0098818 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.00959508 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.00957409 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.00951156 |
| NUP58 | nucleoporin 58 | 0.00946518 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.00933372 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.00932217 |
| MYO1B | myosin IB | 0.00932067 |
| CELSR1 | cadherin, EGF LAG seven-pass G-type receptor 1 | 0.00926086 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.00908145 |
| MAL2 | mal, T-cell differentiation protein 2 (gene/pseudogene) | 0.00892526 |
| ANO6 | anoctamin 6 | 0.00867731 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.00858847 |
| AGRN | agrin | 0.00854069 |
| NCKAP1 | NCK-associated protein 1 | 0.00848532 |
| DDIT3 | DNA-damage-inducible transcript 3 | 0.00847306 |
| QKI | QKI, KH domain containing, RNA binding | 0.00845084 |
| NAB2 | NGFI-A binding protein 2 (EGR1 binding protein 2) | 0.0083809 |
| NDUFV2 | NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa | 0.00835698 |
| MPZL2 | myelin protein zero-like 2 | 0.00832811 |
| KDM6B | lysine (K)-specific demethylase 6B | 0.00822907 |
| TPD52 | tumor protein D52 | 0.00811319 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.00807992 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F | 0.00806037 |
| PPP1R15B | protein phosphatase 1, regulatory subunit 15B | 0.00803975 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | 0.00803589 |
| CLMN | calmin (calponin-like, transmembrane) | 0.00803223 |
| ITGB5 | integrin, beta 5 | 0.00802539 |
| RHOV | ras homolog family member V | 0.00795013 |
| TMEM45B | transmembrane protein 45B | 0.00791222 |
| FBXL5 | F-box and leucine-rich repeat protein 5 | 0.00788738 |
| NCOA3 | nuclear receptor coactivator 3 | 0.00787358 |
| MCL1 | myeloid cell leukemia 1 | 0.00780743 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.440018 |
| UBC | ubiquitin C | -0.137254 |
| EGFR | epidermal growth factor receptor | -0.134829 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.115505 |
| TMSB10 | thymosin beta 10 | -0.0963524 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0809971 |
| MT2A | metallothionein 2A | -0.0782517 |
| PTMA | prothymosin, alpha | -0.0759072 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0719412 |
| RPS27A | ribosomal protein S27a | -0.0711258 |
| ASPH | aspartate beta-hydroxylase | -0.0702815 |
| ENO1 | enolase 1, (alpha) | -0.06989 |
| TXNRD1 | thioredoxin reductase 1 | -0.0664249 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.056801 |
| RPS3 | ribosomal protein S3 | -0.0560893 |
| S100A10 | S100 calcium binding protein A10 | -0.0545047 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0531559 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0501169 |
| RPS24 | ribosomal protein S24 | -0.0496299 |
| CANX | calnexin | -0.0488016 |
| RPS25 | ribosomal protein S25 | -0.0482583 |
| AHNAK | AHNAK nucleoprotein | -0.0471547 |
| RPS8 | ribosomal protein S8 | -0.0461063 |
| RPLP1 | ribosomal protein, large, P1 | -0.045873 |
| LAMC2 | laminin, gamma 2 | -0.0448475 |
| LDHA | lactate dehydrogenase A | -0.0432826 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0412532 |
| RPL37A | ribosomal protein L37a | -0.0406066 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0380645 |
| RPL31 | ribosomal protein L31 | -0.0368869 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0366627 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.035558 |
| KRT18 | keratin 18, type I | -0.0344118 |
| RPL19 | ribosomal protein L19 | -0.0340911 |
| SEC61G | Sec61 gamma subunit | -0.0335115 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0333174 |
| FTL | ferritin, light polypeptide | -0.0332212 |
| OSMR | oncostatin M receptor | -0.0323356 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0322639 |
| TOP1 | topoisomerase (DNA) I | -0.0322612 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0321789 |
| RPS6 | ribosomal protein S6 | -0.0318414 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0317796 |
| ACTG1 | actin gamma 1 | -0.0314838 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0313258 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.03081 |
| STC1 | stanniocalcin 1 | -0.0307549 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | -0.0306957 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.030569 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0302945 |
| PKM | pyruvate kinase, muscle | -0.0300003 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0295623 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0287356 |
| GRAMD1B | GRAM domain containing 1B | -0.0284107 |
| RPL34 | ribosomal protein L34 | -0.0283563 |
| RPS12 | ribosomal protein S12 | -0.0282343 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0280293 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0278313 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0278026 |
| RPS23 | ribosomal protein S23 | -0.0277866 |
| USP34 | ubiquitin specific peptidase 34 | -0.0277184 |
| HLA-B | major histocompatibility complex, class I, B | -0.0276123 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0274597 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0271441 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0271027 |
| RPL35A | ribosomal protein L35a | -0.026483 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0263265 |
| GOLGA4 | golgin A4 | -0.0261338 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0259648 |
| GOLGB1 | golgin B1 | -0.0259027 |
| MYO1D | myosin ID | -0.0257582 |
| RPL23 | ribosomal protein L23 | -0.0254014 |
| SENP5 | SUMO1/sentrin specific peptidase 5 | -0.0253517 |
| RPS17 | ribosomal protein S17 | -0.0252371 |
| TRIM56 | tripartite motif containing 56 | -0.0252041 |
| SEPTIN2 | septin 2 | -0.0251943 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0250208 |
| RPL26 | ribosomal protein L26 | -0.0248605 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0246926 |
| RPLP0 | ribosomal protein, large, P0 | -0.0246875 |
| SMYD3 | SET and MYND domain containing 3 | -0.024605 |
| RPL9 | ribosomal protein L9 | -0.0246027 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0245707 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0245505 |
| RPL8 | ribosomal protein L8 | -0.0245416 |
| RPL5 | ribosomal protein L5 | -0.0245181 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0244731 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0244236 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0244199 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0243512 |
| RPL4 | ribosomal protein L4 | -0.0240574 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0235948 |
| VCL | vinculin | -0.0235458 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0235198 |
| LANCL2 | LanC lantibiotic synthetase component C-like 2 (bacterial) | -0.0235128 |
| RPL12 | ribosomal protein L12 | -0.0234856 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0232791 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0231742 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0230548 |
| RPL11 | ribosomal protein L11 | -0.0230204 |
