| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Abiraterone acetate perturbation in NCI-H2030 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Abiraterone acetate_NCI-H2030 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.140597 |
| IGF2 | insulin-like growth factor 2 | 0.0893946 |
| ACTG1 | actin gamma 1 | 0.0792955 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0788359 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0635042 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.0625021 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0596276 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.0554932 |
| PARD3 | par-3 family cell polarity regulator | 0.0546557 |
| PYGL | phosphorylase, glycogen, liver | 0.0511455 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.047507 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0469932 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0462818 |
| DOCK4 | dedicator of cytokinesis 4 | 0.04555 |
| FMNL2 | formin-like 2 | 0.0448078 |
| CMIP | c-Maf inducing protein | 0.0442673 |
| EGFR | epidermal growth factor receptor | 0.041461 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0393903 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0383287 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0345071 |
| FLNB | filamin B, beta | 0.033105 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | 0.0307104 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0304377 |
| PTK2 | protein tyrosine kinase 2 | 0.0303075 |
| HLA-C | major histocompatibility complex, class I, C | 0.0302491 |
| ERBIN | erbb2 interacting protein | 0.0293529 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.029219 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0286283 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0286274 |
| CAVIN1 | caveolae associated protein 1 | 0.0280262 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0274137 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0273414 |
| CYTH1 | cytohesin 1 | 0.0269204 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0266592 |
| UTRN | utrophin | 0.0266523 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0265669 |
| PRRC2A | proline-rich coiled-coil 2A | 0.0261374 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0260799 |
| NDRG1 | N-myc downstream regulated 1 | 0.0257706 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0251114 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | 0.0242632 |
| FNBP1L | formin binding protein 1-like | 0.0232342 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0230242 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0229981 |
| MEF2D | myocyte enhancer factor 2D | 0.0225834 |
| EXT1 | exostosin glycosyltransferase 1 | 0.022404 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.0223813 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0223712 |
| SVIL | supervillin | 0.0219064 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0219042 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0216439 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0214472 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0213872 |
| RPL13A | ribosomal protein L13a | 0.0212668 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0211374 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.021078 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0208636 |
| FLNA | filamin A, alpha | 0.0199339 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | 0.0196983 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0195035 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0194073 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | 0.0191645 |
| RBM8A | RNA binding motif protein 8A | 0.0190001 |
| PLEC | plectin | 0.0187272 |
| ACTN1 | actinin, alpha 1 | 0.0185934 |
| RBM39 | RNA binding motif protein 39 | 0.0184204 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0183348 |
| VCL | vinculin | 0.0182334 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0182004 |
| SBF2 | SET binding factor 2 | 0.0179531 |
| STC2 | stanniocalcin 2 | 0.0179017 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0178297 |
| SLC25A6 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6 | 0.0177812 |
| CHN1 | chimerin 1 | 0.0176363 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0176339 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0176276 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0175116 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.0174407 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.017371 |
| RPL3 | ribosomal protein L3 | 0.0173424 |
| KIRREL1 | kirre like nephrin family adhesion molecule 1 | 0.0173391 |
| DCAF8 | DDB1 and CUL4 associated factor 8 | 0.0173278 |
| ANGPTL4 | angiopoietin-like 4 | 0.0173132 |
| ITGB5 | integrin, beta 5 | 0.0172157 |
| CABIN1 | calcineurin binding protein 1 | 0.0171124 |
| MRTFA | myocardin related transcription factor A | 0.0171005 |
| CASC3 | cancer susceptibility candidate 3 | 0.0170662 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0170625 |
| DIP2B | DIP2 disco-interacting protein 2 homolog B (Drosophila) | 0.0167384 |
| SIK3 | SIK family kinase 3 | 0.0165717 |
| RASAL2 | RAS protein activator like 2 | 0.0164953 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0164711 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0164418 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0163905 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.016304 |
| RPL35A | ribosomal protein L35a | 0.0160187 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0159483 |
| ZNF335 | zinc finger protein 335 | 0.0159361 |
| BMPR1B | bone morphogenetic protein receptor, type IB | 0.0159325 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0158398 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.189077 |
| PM20D1 | peptidase M20 domain containing 1 | -0.135678 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.120615 |
| GRAMD1B | GRAM domain containing 1B | -0.117742 |
| VIM | vimentin | -0.109152 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0827068 |
| RPS27A | ribosomal protein S27a | -0.0805872 |
| UBC | ubiquitin C | -0.0803876 |
| PTMA | prothymosin, alpha | -0.0758011 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0689335 |
| TXNRD1 | thioredoxin reductase 1 | -0.0686002 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0652807 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.05991 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0559103 |
| FTL | ferritin, light polypeptide | -0.0555616 |
| ASPH | aspartate beta-hydroxylase | -0.0518666 |
| FGB | fibrinogen beta chain | -0.0515087 |
| WWOX | WW domain containing oxidoreductase | -0.0473423 |
| RPL23 | ribosomal protein L23 | -0.0463874 |
| LANCL1 | LanC lantibiotic synthetase component C-like 1 (bacterial) | -0.0393807 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0369425 |
| RPL19 | ribosomal protein L19 | -0.033704 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0333521 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0324481 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0296735 |
| RPS15 | ribosomal protein S15 | -0.0292787 |
| ENO1 | enolase 1, (alpha) | -0.0285111 |
| RPS23 | ribosomal protein S23 | -0.0272046 |
| MT2A | metallothionein 2A | -0.0268641 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0254717 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0252958 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.024356 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0240799 |
| AREG | amphiregulin | -0.023621 |
| IER3 | immediate early response 3 | -0.023542 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0234711 |
| RPS29 | ribosomal protein S29 | -0.0233701 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0233051 |
| TUBA1B | tubulin, alpha 1b | -0.023208 |
| TNPO1 | transportin 1 | -0.0229776 |
| CCT5 | chaperonin containing TCP1, subunit 5 (epsilon) | -0.0229345 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | -0.0225235 |
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | -0.0222248 |
| RPS5 | ribosomal protein S5 | -0.0221239 |
| RPL9 | ribosomal protein L9 | -0.0220435 |
| KLF6 | Kruppel-like factor 6 | -0.0218444 |
| RPL8 | ribosomal protein L8 | -0.021798 |
| SRP14 | signal recognition particle 14kDa (homologous Alu RNA binding protein) | -0.0217213 |
| NNMT | nicotinamide N-methyltransferase | -0.0212095 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0211284 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0210235 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0208672 |
| RPS24 | ribosomal protein S24 | -0.0206634 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0202902 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0200704 |
| NTN4 | netrin 4 | -0.0191064 |
| PKM | pyruvate kinase, muscle | -0.019097 |
| RPS25 | ribosomal protein S25 | -0.0190201 |
| CCT8 | chaperonin containing TCP1, subunit 8 (theta) | -0.0189258 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0188945 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0187578 |
| RTN4 | reticulon 4 | -0.0187514 |
| FGG | fibrinogen gamma chain | -0.0187047 |
| S100A10 | S100 calcium binding protein A10 | -0.0187043 |
| SFPQ | splicing factor proline/glutamine-rich | -0.0186941 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | -0.0185598 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0185465 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | -0.0184609 |
| HMGB1 | high mobility group box 1 | -0.0183837 |
| RPS11 | ribosomal protein S11 | -0.0181405 |
| RPS8 | ribosomal protein S8 | -0.0180377 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0176025 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0173659 |
| RPL4 | ribosomal protein L4 | -0.0172184 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.01695 |
| RPLP2 | ribosomal protein, large, P2 | -0.0169174 |
| NDUFB3 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa | -0.016833 |
| RPS12 | ribosomal protein S12 | -0.0168072 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.0167954 |
| PAPOLA | poly(A) polymerase alpha | -0.016683 |
| RPS16 | ribosomal protein S16 | -0.0166311 |
| RPLP0 | ribosomal protein, large, P0 | -0.0165856 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0165624 |
| FAM107B | family with sequence similarity 107, member B | -0.0163281 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0159894 |
| RPL15 | ribosomal protein L15 | -0.0150457 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.015023 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.0149334 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | -0.0149106 |
| RPLP1 | ribosomal protein, large, P1 | -0.0148606 |
| CALU | calumenin | -0.0148388 |
| DENND4A | DENN/MADD domain containing 4A | -0.0148112 |
| RPL36A | ribosomal protein L36a | -0.0147115 |
| ZFAND6 | zinc finger, AN1-type domain 6 | -0.0146567 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0146173 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | -0.0145843 |
| CBX3 | chromobox homolog 3 | -0.0145137 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0143976 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | -0.0142488 |
| ATP5F1E | ATP synthase F1 subunit epsilon | -0.0141912 |
