| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Abiraterone acetate perturbation in NCI-H23 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Abiraterone acetate_NCI-H23 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TXNRD1 | thioredoxin reductase 1 | 0.20588 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.132635 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0809604 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0713197 |
| GRAMD1B | GRAM domain containing 1B | 0.0679363 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0637127 |
| RTN4 | reticulon 4 | 0.0558659 |
| TPM3 | tropomyosin 3 | 0.0488345 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0458551 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0428538 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.042139 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0398409 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0386435 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0373796 |
| MARCHF4 | membrane associated ring-CH-type finger 4 | 0.0373094 |
| XPO1 | exportin 1 | 0.0372013 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0357566 |
| PLEC | plectin | 0.0352828 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0352791 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0350344 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0331258 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0302506 |
| CTTNBP2NL | CTTNBP2 N-terminal like | 0.0299344 |
| YES1 | YES proto-oncogene 1, Src family tyrosine kinase | 0.0295013 |
| RUSC2 | RUN and SH3 domain containing 2 | 0.0293651 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0286881 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0275866 |
| PRRC2A | proline-rich coiled-coil 2A | 0.0261037 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0258615 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0254551 |
| RPL3 | ribosomal protein L3 | 0.0248229 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.024642 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0245083 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0237373 |
| CHD4 | chromodomain helicase DNA binding protein 4 | 0.02335 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.022695 |
| RASAL2 | RAS protein activator like 2 | 0.0224184 |
| PPME1 | protein phosphatase methylesterase 1 | 0.0221664 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0221283 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0220683 |
| GPHN | gephyrin | 0.0220527 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0220155 |
| MSH6 | mutS homolog 6 | 0.0219198 |
| IL6ST | interleukin 6 signal transducer | 0.0208618 |
| CLTC | clathrin, heavy chain (Hc) | 0.0208473 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0199459 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0199439 |
| ANXA5 | annexin A5 | 0.0197336 |
| MYO10 | myosin X | 0.0196318 |
| IPO7 | importin 7 | 0.0194707 |
| KIF5B | kinesin family member 5B | 0.0194703 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0193977 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0193309 |
| TMEM41B | transmembrane protein 41B | 0.0192725 |
| DENR | density-regulated protein | 0.0188834 |
| GATAD2B | GATA zinc finger domain containing 2B | 0.0188524 |
| YBX3 | Y box binding protein 3 | 0.018705 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.018681 |
| SRSF5 | serine/arginine-rich splicing factor 5 | 0.0185778 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0184924 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0183954 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0183323 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | 0.0182691 |
| ACTN1 | actinin, alpha 1 | 0.0182176 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0181513 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0181172 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0180124 |
| MATR3 | matrin 3 | 0.0179454 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0178148 |
| STC1 | stanniocalcin 1 | 0.0177155 |
| KDM7A | lysine (K)-specific demethylase 7A | 0.0176976 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0176715 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0176112 |
| PLSCR1 | phospholipid scramblase 1 | 0.0175986 |
| SINHCAF | SIN3-HDAC complex associated factor | 0.0174985 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | 0.0174462 |
| PHIP | pleckstrin homology domain interacting protein | 0.0171187 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.016721 |
| REL | v-rel avian reticuloendotheliosis viral oncogene homolog | 0.0167154 |
| PFDN2 | prefoldin subunit 2 | 0.0166401 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0165865 |
| RECQL | RecQ helicase-like | 0.0163421 |
| JMJD1C | jumonji domain containing 1C | 0.0161779 |
| PCBP2 | poly(rC) binding protein 2 | 0.0161543 |
| CDYL | chromodomain protein, Y-like | 0.0161324 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0161005 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0159927 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0159412 |
| SNX9 | sorting nexin 9 | 0.0159375 |
| CTSL | cathepsin L | 0.0157825 |
| KLF6 | Kruppel-like factor 6 | 0.0157567 |
| MYPN | myopalladin | 0.0157409 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.015614 |
| HELZ2 | helicase with zinc finger 2, transcriptional coactivator | 0.0155043 |
| AXL | AXL receptor tyrosine kinase | 0.0153722 |
| MKI67 | marker of proliferation Ki-67 | 0.0153506 |
| AMOTL2 | angiomotin like 2 | 0.0152277 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | 0.0151764 |
| HNRNPH3 | heterogeneous nuclear ribonucleoprotein H3 (2H9) | 0.0150475 |
| CEP250 | centrosomal protein 250kDa | 0.0149128 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.360773 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.149158 |
| TMSB10 | thymosin beta 10 | -0.0880519 |
| PTMA | prothymosin, alpha | -0.0759356 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0746938 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0736004 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0725367 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0646324 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0640503 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0640331 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0638651 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0589849 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0583502 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0576309 |
| PRELID2 | PRELI domain containing 2 | -0.0569258 |
| ACTG1 | actin gamma 1 | -0.0560363 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0550487 |
| PDE10A | phosphodiesterase 10A | -0.0542679 |
| ATXN1 | ataxin 1 | -0.0524313 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0517302 |
| AEBP2 | AE binding protein 2 | -0.0509075 |
| RAD51B | RAD51 paralog B | -0.0498839 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0495275 |
| HMGA2 | high mobility group AT-hook 2 | -0.049282 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.048957 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.045494 |
| RPL35A | ribosomal protein L35a | -0.0434948 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | -0.0425217 |
| RYR3 | ryanodine receptor 3 | -0.0420624 |
| MCL1 | myeloid cell leukemia 1 | -0.0417886 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0414042 |
| RPL37A | ribosomal protein L37a | -0.0412366 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0411992 |
| INTS6 | integrator complex subunit 6 | -0.0397296 |
| EXOC4 | exocyst complex component 4 | -0.0396755 |
| RPS8 | ribosomal protein S8 | -0.0391367 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0389574 |
| EGR1 | early growth response 1 | -0.0371597 |
| HLA-B | major histocompatibility complex, class I, B | -0.0363029 |
| EHBP1 | EH domain binding protein 1 | -0.0340375 |
| POTEF | POTE ankyrin domain family, member F | -0.0334749 |
| RBM39 | RNA binding motif protein 39 | -0.0324613 |
| VIM | vimentin | -0.0321808 |
| USP34 | ubiquitin specific peptidase 34 | -0.0316625 |
| WNT2B | wingless-type MMTV integration site family, member 2B | -0.0316331 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.031583 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0311857 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0304938 |
| RPL37 | ribosomal protein L37 | -0.0304004 |
| VCL | vinculin | -0.0303301 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0299861 |
| RPS29 | ribosomal protein S29 | -0.029543 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0293469 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0293377 |
| RPL31 | ribosomal protein L31 | -0.0293314 |
| SETD5 | SET domain containing 5 | -0.0290784 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0290112 |
| RPL26 | ribosomal protein L26 | -0.0289205 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0285753 |
| CUX1 | cut-like homeobox 1 | -0.0283823 |
| ATG7 | autophagy related 7 | -0.0283803 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0281549 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0280134 |
| RPL11 | ribosomal protein L11 | -0.0267947 |
| RPS15 | ribosomal protein S15 | -0.026777 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0265235 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0260702 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0260395 |
| PYGL | phosphorylase, glycogen, liver | -0.0260071 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0259776 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | -0.0258838 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0257265 |
| RPS21 | ribosomal protein S21 | -0.0257261 |
| SMYD3 | SET and MYND domain containing 3 | -0.025718 |
| RPS19 | ribosomal protein S19 | -0.0255857 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0254502 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | -0.025263 |
| RPS27A | ribosomal protein S27a | -0.0251161 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0251078 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.0250549 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.02486 |
| RPS10 | ribosomal protein S10 | -0.0241603 |
| RSF1 | remodeling and spacing factor 1 | -0.0241019 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0239477 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0239336 |
| FMN1 | formin 1 | -0.0236191 |
| GNAS | GNAS complex locus | -0.0235504 |
| RPS6 | ribosomal protein S6 | -0.0232642 |
| LRCH3 | leucine-rich repeats and calponin homology (CH) domain containing 3 | -0.0226548 |
| RYK | receptor-like tyrosine kinase | -0.0225633 |
| BBX | bobby sox homolog (Drosophila) | -0.0225588 |
| GPATCH2L | G patch domain containing 2-like | -0.0225118 |
| RPL38 | ribosomal protein L38 | -0.0220581 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0217772 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0217698 |
| RPS27 | ribosomal protein S27 | -0.0215127 |
| RPL28 | ribosomal protein L28 | -0.0214528 |
| KIAA1328 | KIAA1328 | -0.0213946 |
| RPS24 | ribosomal protein S24 | -0.0213743 |
| DIAPH2 | diaphanous-related formin 2 | -0.0213736 |
