| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Abiraterone acetate perturbation in NCI-H460 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Abiraterone acetate_NCI-H460 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.103027 |
| EFNA5 | ephrin-A5 | 0.0668009 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0575759 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.0540232 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0506104 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0481837 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0464289 |
| COL4A6 | collagen, type IV, alpha 6 | 0.038856 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0362692 |
| MYOF | myoferlin | 0.0342039 |
| CTSC | cathepsin C | 0.0337847 |
| DNER | delta/notch-like EGF repeat containing | 0.0335562 |
| PTEN | phosphatase and tensin homolog | 0.0322755 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.030338 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0301197 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0299457 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0281078 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0259114 |
| GDA | guanine deaminase | 0.025579 |
| HLA-C | major histocompatibility complex, class I, C | 0.0217494 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0213278 |
| EPB41L3 | erythrocyte membrane protein band 4.1-like 3 | 0.0201135 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0200011 |
| CD109 | CD109 molecule | 0.0194556 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0193737 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0192764 |
| CUL4A | cullin 4A | 0.0184243 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0181092 |
| DPYD | dihydropyrimidine dehydrogenase | 0.018057 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0175276 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.0169667 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0167984 |
| NEK7 | NIMA-related kinase 7 | 0.0166335 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0160834 |
| RTN1 | reticulon 1 | 0.0157641 |
| RPL3 | ribosomal protein L3 | 0.0155241 |
| ATP13A3 | ATPase type 13A3 | 0.0149009 |
| COL4A5 | collagen, type IV, alpha 5 | 0.0146406 |
| DST | dystonin | 0.0142435 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0138567 |
| RTN4 | reticulon 4 | 0.0137589 |
| ENAH | enabled homolog (Drosophila) | 0.0134125 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.012726 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | 0.0125544 |
| PID1 | phosphotyrosine interaction domain containing 1 | 0.0124549 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0122842 |
| RAD51B | RAD51 paralog B | 0.0122465 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | 0.0121446 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0120644 |
| FLNA | filamin A, alpha | 0.0120174 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.011956 |
| PRRC2A | proline-rich coiled-coil 2A | 0.0118437 |
| S100A6 | S100 calcium binding protein A6 | 0.0117285 |
| AOPEP | aminopeptidase O (putative) | 0.0117067 |
| SP3 | Sp3 transcription factor | 0.0116686 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.011663 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0112741 |
| LAMA5 | laminin, alpha 5 | 0.0112684 |
| EPHA4 | EPH receptor A4 | 0.0112081 |
| EFEMP1 | EGF containing fibulin-like extracellular matrix protein 1 | 0.0111249 |
| CCDC88A | coiled-coil domain containing 88A | 0.0110376 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | 0.0109557 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0108529 |
| ITGB5 | integrin, beta 5 | 0.0108451 |
| PPFIA4 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 | 0.010824 |
| DNMBP | dynamin binding protein | 0.0107793 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0106721 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 0.0106501 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0106386 |
| HJURP | Holliday junction recognition protein | 0.010427 |
| FBXL13 | F-box and leucine-rich repeat protein 13 | 0.0103558 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | 0.0102546 |
| PRKAB2 | protein kinase, AMP-activated, beta 2 non-catalytic subunit | 0.0101637 |
| KIRREL1 | kirre like nephrin family adhesion molecule 1 | 0.0101069 |
| THOC2 | THO complex 2 | 0.0100905 |
| DCAF8 | DDB1 and CUL4 associated factor 8 | 0.0100263 |
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.0100167 |
| LOC112694756 | uncharaterized LOC112694756 | 0.00982622 |
| RIC1 | RAB6A GEF complex partner 1 | 0.009645 |
| SATB2 | SATB homeobox 2 | 0.00959422 |
| MFF | mitochondrial fission factor | 0.00930769 |
| NHSL1 | NHS-like 1 | 0.00928394 |
| CEP170 | centrosomal protein 170kDa | 0.00903309 |
| GOLGA2 | golgin A2 | 0.00898237 |
| MARCHF1 | membrane associated ring-CH-type finger 1 | 0.00890578 |
| FBXL5 | F-box and leucine-rich repeat protein 5 | 0.00883999 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.00872716 |
| FN1 | fibronectin 1 | 0.00868184 |
| CHD1L | chromodomain helicase DNA binding protein 1-like | 0.00864531 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | 0.00862322 |
| CTIF | CBP80/20-dependent translation initiation factor | 0.00859046 |
| SLC25A6 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6 | 0.00854823 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | 0.00848459 |
| RBM26 | RNA binding motif protein 26 | 0.00834845 |
| MOSMO | modulator of smoothened | 0.00826926 |
| METTL15 | methyltransferase like 15 | 0.00826446 |
| FNDC3B | fibronectin type III domain containing 3B | 0.00821001 |
| MYPN | myopalladin | 0.00815748 |
| YEATS2 | YEATS domain containing 2 | 0.00812393 |
| IWS1 | IWS1 homolog (S. cerevisiae) | 0.00811168 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.233268 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.204115 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.17654 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.133027 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.114285 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.114184 |
| PTMA | prothymosin, alpha | -0.108531 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.108441 |
| VIM | vimentin | -0.0813061 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0777529 |
| TXNRD1 | thioredoxin reductase 1 | -0.0772048 |
| RPS24 | ribosomal protein S24 | -0.0764632 |
| DPP10 | dipeptidyl-peptidase 10 (non-functional) | -0.0712925 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0650539 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.0635997 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0632442 |
| FTL | ferritin, light polypeptide | -0.061487 |
| TMSB10 | thymosin beta 10 | -0.0583616 |
| RPS23 | ribosomal protein S23 | -0.0578084 |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 | -0.0576024 |
| RPS6 | ribosomal protein S6 | -0.0566541 |
| RPS8 | ribosomal protein S8 | -0.0534329 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.052307 |
| RPL31 | ribosomal protein L31 | -0.0515811 |
| RPLP1 | ribosomal protein, large, P1 | -0.0510234 |
| RPL37A | ribosomal protein L37a | -0.0503984 |
| PM20D1 | peptidase M20 domain containing 1 | -0.0493987 |
| RPL7A | ribosomal protein L7a | -0.0493368 |
| INHBA | inhibin, beta A | -0.0484434 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0479304 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0457662 |
| RPL36A | ribosomal protein L36a | -0.0436479 |
| CANX | calnexin | -0.043623 |
| B2M | beta-2-microglobulin | -0.0429963 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0429012 |
| PKM | pyruvate kinase, muscle | -0.042815 |
| RPS29 | ribosomal protein S29 | -0.0410384 |
| ENO1 | enolase 1, (alpha) | -0.0409625 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.0407783 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0392929 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0389909 |
| HLA-B | major histocompatibility complex, class I, B | -0.0387811 |
| SQSTM1 | sequestosome 1 | -0.0387008 |
| GRAMD1B | GRAM domain containing 1B | -0.0386977 |
| ASPH | aspartate beta-hydroxylase | -0.0381934 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0381874 |
| RPS27A | ribosomal protein S27a | -0.0381033 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0380427 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0378952 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0375646 |
| RPS13 | ribosomal protein S13 | -0.0363664 |
| RPS25 | ribosomal protein S25 | -0.0362617 |
| RPLP2 | ribosomal protein, large, P2 | -0.0362356 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.036182 |
| PGK1 | phosphoglycerate kinase 1 | -0.0361133 |
| RPS19 | ribosomal protein S19 | -0.0349076 |
| PDE10A | phosphodiesterase 10A | -0.0348041 |
| CTSL | cathepsin L | -0.0343014 |
| RAB3B | RAB3B, member RAS oncogene family | -0.0339516 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0337351 |
| RPL26 | ribosomal protein L26 | -0.0334668 |
| UBC | ubiquitin C | -0.0332072 |
| EZR | ezrin | -0.0327482 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0326856 |
| S100A10 | S100 calcium binding protein A10 | -0.0325926 |
| LDHA | lactate dehydrogenase A | -0.032566 |
| RPL38 | ribosomal protein L38 | -0.0319616 |
| RPS16 | ribosomal protein S16 | -0.0317425 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0314523 |
| RPL19 | ribosomal protein L19 | -0.0308029 |
| RPLP0 | ribosomal protein, large, P0 | -0.0307914 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0303185 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0301684 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0290263 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0289435 |
| MAP1B | microtubule-associated protein 1B | -0.0289015 |
| RPS12 | ribosomal protein S12 | -0.0287156 |
| CADM2 | cell adhesion molecule 2 | -0.0281726 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0279996 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0279744 |
| MAP7 | microtubule-associated protein 7 | -0.027956 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.027793 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0275535 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0275046 |
| ACTG1 | actin gamma 1 | -0.0269401 |
| LSAMP | limbic system-associated membrane protein | -0.0266809 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | -0.0264804 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0263699 |
| P3H2 | prolyl 3-hydroxylase 2 | -0.0261483 |
| RPS15 | ribosomal protein S15 | -0.0261289 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0259673 |
| RPS11 | ribosomal protein S11 | -0.0257967 |
| EXT1 | exostosin glycosyltransferase 1 | -0.025659 |
| GNAS | GNAS complex locus | -0.0252806 |
| IER3 | immediate early response 3 | -0.0252746 |
| IL6 | interleukin 6 | -0.0251343 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0251078 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.025003 |
| RPL11 | ribosomal protein L11 | -0.0246893 |
| RHOB | ras homolog family member B | -0.0244903 |
