| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Abiraterone acetate perturbation in NCI-H596 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Abiraterone acetate_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NDRG1 | N-myc downstream regulated 1 | 0.114144 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.113154 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.103822 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.101615 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0932286 |
| INHBA | inhibin, beta A | 0.0914841 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0815209 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0788014 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 0.078708 |
| NOP58 | NOP58 ribonucleoprotein | 0.0776472 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0754 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | 0.0737611 |
| WDR45B | WD repeat domain 45B | 0.0715602 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.0713492 |
| EIF5B | eukaryotic translation initiation factor 5B | 0.0711624 |
| CD109 | CD109 molecule | 0.0701509 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0695978 |
| VGF | VGF nerve growth factor inducible | 0.0688474 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0682331 |
| NAV2 | neuron navigator 2 | 0.0671458 |
| LIMA1 | LIM domain and actin binding 1 | 0.0668488 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0629741 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0629331 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0625714 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0623491 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.061971 |
| RORA | RAR-related orphan receptor A | 0.0616985 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0599267 |
| PARD3 | par-3 family cell polarity regulator | 0.0592695 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0590194 |
| TFG | TRK-fused gene | 0.058978 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0587524 |
| IGF2 | insulin-like growth factor 2 | 0.0584032 |
| CD44 | CD44 molecule (Indian blood group) | 0.0574711 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0563025 |
| MATR3 | matrin 3 | 0.0558306 |
| WAC | WW domain containing adaptor with coiled-coil | 0.055288 |
| USP3 | ubiquitin specific peptidase 3 | 0.0545235 |
| PCBP2 | poly(rC) binding protein 2 | 0.0537512 |
| NUP58 | nucleoporin 58 | 0.0537079 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0532691 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | 0.0528009 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0521357 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0517222 |
| RLF | rearranged L-myc fusion | 0.0516555 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0515605 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0506892 |
| FOXO3 | forkhead box O3 | 0.0496519 |
| ZNF638 | zinc finger protein 638 | 0.0495087 |
| RPTOR | regulatory associated protein of MTOR, complex 1 | 0.0494725 |
| ATP2C1 | ATPase, Ca++ transporting, type 2C, member 1 | 0.0493052 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0492042 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0490712 |
| ATP11A | ATPase, class VI, type 11A | 0.0490397 |
| FOXJ3 | forkhead box J3 | 0.0489831 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | 0.0488725 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0485817 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.048513 |
| ADM | adrenomedullin | 0.0482556 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | 0.048033 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0479586 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | 0.0474841 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0467926 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | 0.0466516 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0462497 |
| VMP1 | vacuole membrane protein 1 | 0.0460105 |
| KIAA1217 | KIAA1217 | 0.0460079 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0458862 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0454917 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0445657 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0443202 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.0432886 |
| ZNF292 | zinc finger protein 292 | 0.042929 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.042497 |
| PTGES2 | prostaglandin E synthase 2 | 0.0423224 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | 0.0423125 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0414681 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0413089 |
| SPAG9 | sperm associated antigen 9 | 0.0410629 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0404844 |
| ENO1 | enolase 1, (alpha) | 0.0395091 |
| WDFY2 | WD repeat and FYVE domain containing 2 | 0.0386398 |
| SMAD3 | SMAD family member 3 | 0.0384643 |
| HELZ | helicase with zinc finger | 0.0381604 |
| RUNX1 | runt-related transcription factor 1 | 0.0379783 |
| SLC2A13 | solute carrier family 2 (facilitated glucose transporter), member 13 | 0.0377113 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | 0.0376787 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.0362207 |
| EFNA5 | ephrin-A5 | 0.0361003 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | 0.0360863 |
| COPA | coatomer protein complex, subunit alpha | 0.0360593 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0359377 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0357721 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0357278 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0356141 |
| GOLGA4 | golgin A4 | 0.0354028 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0353739 |
| AHR | aryl hydrocarbon receptor | 0.0352523 |
| TENM3 | teneurin transmembrane protein 3 | 0.0351903 |
| RPS27A | ribosomal protein S27a | 0.034956 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.188533 |
| VIM | vimentin | -0.151709 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.112986 |
| PKM | pyruvate kinase, muscle | -0.107375 |
| ASPH | aspartate beta-hydroxylase | -0.100347 |
| TMSB10 | thymosin beta 10 | -0.0891293 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.087285 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0855999 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0818002 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0809151 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0788092 |
| AHNAK | AHNAK nucleoprotein | -0.0766224 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0760228 |
| PTMA | prothymosin, alpha | -0.07569 |
| RPL11 | ribosomal protein L11 | -0.0735254 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0734345 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0702317 |
| STC1 | stanniocalcin 1 | -0.0694462 |
| CCNI | cyclin I | -0.0684235 |
| TXNRD1 | thioredoxin reductase 1 | -0.0683771 |
| INTS6 | integrator complex subunit 6 | -0.0674148 |
| S100A9 | S100 calcium binding protein A9 | -0.0673354 |
| MAP4 | microtubule-associated protein 4 | -0.0669765 |
| LDHA | lactate dehydrogenase A | -0.0665797 |
| NAV1 | neuron navigator 1 | -0.0660033 |
| PRELID2 | PRELI domain containing 2 | -0.0650007 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.0637691 |
| TAOK3 | TAO kinase 3 | -0.060804 |
| LOXL2 | lysyl oxidase-like 2 | -0.0603779 |
| OSMR | oncostatin M receptor | -0.058112 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -0.0551732 |
| UBC | ubiquitin C | -0.0549751 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0549529 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0545905 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0533373 |
| RPL37A | ribosomal protein L37a | -0.052857 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0526552 |
| ERCC6L2 | excision repair cross-complementation group 6-like 2 | -0.0512779 |
| B2M | beta-2-microglobulin | -0.0510941 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0509614 |
| HMGA2 | high mobility group AT-hook 2 | -0.0507022 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0503119 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0500952 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0500858 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0497493 |
| MYO1E | myosin IE | -0.0492097 |
| POTEF | POTE ankyrin domain family, member F | -0.048481 |
| CDH13 | cadherin 13 | -0.04842 |
| SP100 | SP100 nuclear antigen | -0.0471095 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0467277 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0467202 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0462741 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.045906 |
| CNKSR3 | CNKSR family member 3 | -0.0455449 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0448081 |
| RPS8 | ribosomal protein S8 | -0.0444818 |
| MX2 | MX dynamin-like GTPase 2 | -0.0441537 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0440863 |
| AUTS2 | autism susceptibility candidate 2 | -0.0431243 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0431146 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | -0.0430266 |
| SETD5 | SET domain containing 5 | -0.0424313 |
| CDCP1 | CUB domain containing protein 1 | -0.0417404 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | -0.0414031 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0412752 |
| HLA-B | major histocompatibility complex, class I, B | -0.0411412 |
| NF1 | neurofibromin 1 | -0.0402509 |
| MAP1B | microtubule-associated protein 1B | -0.0394957 |
| COL5A2 | collagen, type V, alpha 2 | -0.0394209 |
| MT2A | metallothionein 2A | -0.0393863 |
| MCL1 | myeloid cell leukemia 1 | -0.0391555 |
| CARD16 | caspase recruitment domain family, member 16 | -0.0382892 |
| FOXP1 | forkhead box P1 | -0.0379815 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0375395 |
| SNX14 | sorting nexin 14 | -0.0374253 |
| RPL26 | ribosomal protein L26 | -0.0373187 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0367169 |
| ITSN2 | intersectin 2 | -0.0364156 |
| SCFD1 | sec1 family domain containing 1 | -0.0363388 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0361964 |
| VEGFA | vascular endothelial growth factor A | -0.0356865 |
| TOR1AIP2 | torsin A interacting protein 2 | -0.0356781 |
| VCL | vinculin | -0.034019 |
| RPL19 | ribosomal protein L19 | -0.0340056 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0338642 |
| CANX | calnexin | -0.0337684 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0334434 |
| ATF6 | activating transcription factor 6 | -0.0334195 |
| FN1 | fibronectin 1 | -0.0333716 |
| PDE10A | phosphodiesterase 10A | -0.0331385 |
| EXOC6B | exocyst complex component 6B | -0.0325262 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | -0.0324929 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0324495 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0319666 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0319351 |
| RPS17 | ribosomal protein S17 | -0.0318832 |
| KCTD9 | potassium channel tetramerization domain containing 9 | -0.0317479 |
| BRD4 | bromodomain containing 4 | -0.0310096 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0305647 |
| SEC62 | SEC62 homolog (S. cerevisiae) | -0.0302859 |
