| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Abiraterone acetate perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Abiraterone acetate_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | 0.0412718 |
| PARD3B | par-3 family cell polarity regulator beta | 0.0387172 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0327611 |
| PRRC2A | proline-rich coiled-coil 2A | 0.0280512 |
| SHROOM3 | shroom family member 3 | 0.0278993 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0269126 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0267207 |
| ADGRL3 | adhesion G protein-coupled receptor L3 | 0.0251267 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0229627 |
| PHLPP1 | PH domain and leucine rich repeat protein phosphatase 1 | 0.0224343 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | 0.02195 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0218404 |
| RPL3 | ribosomal protein L3 | 0.0214137 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0212263 |
| BRD2 | bromodomain containing 2 | 0.0207188 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0205118 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0203676 |
| HYOU1 | hypoxia up-regulated 1 | 0.0202164 |
| SERTAD2 | SERTA domain containing 2 | 0.0199778 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | 0.0191465 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0191146 |
| TRPS1 | trichorhinophalangeal syndrome I | 0.0190479 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0190133 |
| NFIB | nuclear factor I/B | 0.0189993 |
| UBAP2L | ubiquitin associated protein 2-like | 0.0189437 |
| USP25 | ubiquitin specific peptidase 25 | 0.0187162 |
| INTS6 | integrator complex subunit 6 | 0.0186163 |
| FN1 | fibronectin 1 | 0.0185565 |
| PLEC | plectin | 0.0181602 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.018149 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0180849 |
| CSMD3 | CUB and Sushi multiple domains 3 | 0.0179152 |
| TJP1 | tight junction protein 1 | 0.0178583 |
| SATB2 | SATB homeobox 2 | 0.0178454 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0175447 |
| NCAM2 | neural cell adhesion molecule 2 | 0.0170503 |
| CORO1C | coronin, actin binding protein, 1C | 0.0165926 |
| JAZF1 | JAZF zinc finger 1 | 0.0165069 |
| PER1 | period circadian clock 1 | 0.0161964 |
| GAB2 | GRB2-associated binding protein 2 | 0.0161068 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0160625 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.0160447 |
| AKT2 | v-akt murine thymoma viral oncogene homolog 2 | 0.0158454 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0156685 |
| XPR1 | xenotropic and polytropic retrovirus receptor 1 | 0.0156311 |
| PCF11 | PCF11 cleavage and polyadenylation factor subunit | 0.015553 |
| MSRB3 | methionine sulfoxide reductase B3 | 0.0155253 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0154902 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0154002 |
| SEMA3E | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E | 0.0153607 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0152896 |
| WDR43 | WD repeat domain 43 | 0.01527 |
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) | 0.0152357 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0151741 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0151298 |
| HSPA8 | heat shock 70kDa protein 8 | 0.015114 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0151094 |
| MAPK1 | mitogen-activated protein kinase 1 | 0.0150052 |
| TTC28 | tetratricopeptide repeat domain 28 | 0.0149943 |
| CAPRIN1 | cell cycle associated protein 1 | 0.0149892 |
| PRR16 | proline rich 16 | 0.0149345 |
| PDGFC | platelet derived growth factor C | 0.0148196 |
| HMGA2 | high mobility group AT-hook 2 | 0.0147385 |
| FBXO11 | F-box protein 11 | 0.0147286 |
| SLC44A5 | solute carrier family 44, member 5 | 0.0146628 |
| TMEM14C | transmembrane protein 14C | 0.0146439 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0145839 |
| CREBZF | CREB/ATF bZIP transcription factor | 0.0145219 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0144335 |
| ETNK1 | ethanolamine kinase 1 | 0.0144213 |
| RNF40 | ring finger protein 40, E3 ubiquitin protein ligase | 0.0144198 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0143341 |
| BCORL1 | BCL6 corepressor-like 1 | 0.0143253 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0142876 |
| RIC1 | RAB6A GEF complex partner 1 | 0.0142838 |
| GADD45B | growth arrest and DNA-damage-inducible, beta | 0.0142415 |
| GPATCH2L | G patch domain containing 2-like | 0.0142387 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0142206 |
| AGTPBP1 | ATP/GTP binding protein 1 | 0.0141664 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0141547 |
| TTC17 | tetratricopeptide repeat domain 17 | 0.0141031 |
| PLCG1 | phospholipase C, gamma 1 | 0.0139836 |
| RIGI | RNA sensor RIG-I | 0.0139819 |
| NAV3 | neuron navigator 3 | 0.0139407 |
| CCDC102B | coiled-coil domain containing 102B | 0.0139181 |
| OBSCN | obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF | 0.0138253 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | 0.0138081 |
| MYL9 | myosin, light chain 9, regulatory | 0.0137431 |
| SIK2 | salt-inducible kinase 2 | 0.0136939 |
| MED26 | mediator complex subunit 26 | 0.0136594 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0135901 |
| SPIRE1 | spire-type actin nucleation factor 1 | 0.0134461 |
| NAB2 | NGFI-A binding protein 2 (EGR1 binding protein 2) | 0.0134413 |
| PAK4 | p21 protein (Cdc42/Rac)-activated kinase 4 | 0.0134073 |
| ELOVL5 | ELOVL fatty acid elongase 5 | 0.0133744 |
| ACTN1 | actinin, alpha 1 | 0.013354 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0133538 |
| APPBP2 | amyloid beta precursor protein (cytoplasmic tail) binding protein 2 | 0.0133071 |
| CHD9 | chromodomain helicase DNA binding protein 9 | 0.0132756 |
| SMG6 | SMG6 nonsense mediated mRNA decay factor | 0.0132612 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.216532 |
| VIM | vimentin | -0.188863 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.137846 |
| PTMA | prothymosin, alpha | -0.118504 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.115456 |
| GPC3 | glypican 3 | -0.108807 |
| COL3A1 | collagen, type III, alpha 1 | -0.104772 |
| RPS16 | ribosomal protein S16 | -0.094101 |
| SNX6 | sorting nexin 6 | -0.0848854 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0824295 |
| RPS8 | ribosomal protein S8 | -0.0773797 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0748505 |
| TMSB4X | thymosin beta 4, X-linked | -0.0697621 |
| PHIP | pleckstrin homology domain interacting protein | -0.0681787 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0669561 |
| COL11A1 | collagen, type XI, alpha 1 | -0.0636805 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | -0.0611591 |
| COL1A2 | collagen, type I, alpha 2 | -0.0588851 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0588677 |
| RPS6 | ribosomal protein S6 | -0.058108 |
| RPS2 | ribosomal protein S2 | -0.0572939 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.056866 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0565839 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0564784 |
| H1-0 | H1.0 linker histone | -0.0561705 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0560609 |
| RAI1 | retinoic acid induced 1 | -0.0546607 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0537128 |
| TMSB10 | thymosin beta 10 | -0.0531254 |
| PGK1 | phosphoglycerate kinase 1 | -0.052585 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0521826 |
| SOX2 | SRY (sex determining region Y)-box 2 | -0.0520462 |
| MAP4 | microtubule-associated protein 4 | -0.0511779 |
| ANKRD33B | ankyrin repeat domain 33B | -0.0495912 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0490969 |
| SRP54 | signal recognition particle 54kDa | -0.0484568 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0479192 |
| APP | amyloid beta (A4) precursor protein | -0.0476487 |
| PCDH9 | protocadherin 9 | -0.0475455 |
| PEG10 | paternally expressed 10 | -0.0472797 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0472213 |
| ZNF292 | zinc finger protein 292 | -0.0471912 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0469143 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0467364 |
| ZFR | zinc finger RNA binding protein | -0.0465161 |
| ITGAV | integrin, alpha V | -0.0463096 |
| RPLP1 | ribosomal protein, large, P1 | -0.0455888 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0454468 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.0454271 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0453949 |
| THOC2 | THO complex 2 | -0.0448831 |
| ENO1 | enolase 1, (alpha) | -0.0432519 |
| RAB31 | RAB31, member RAS oncogene family | -0.0425544 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.0423917 |
| EMP1 | epithelial membrane protein 1 | -0.041997 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0417314 |
| NTM | neurotrimin | -0.0415708 |
| RFPL4B | ret finger protein-like 4B | -0.0408953 |
| LSM14A | LSM14A, SCD6 homolog A (S. cerevisiae) | -0.0407349 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0400863 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.039733 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0397217 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0385284 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0385178 |
| RPLP2 | ribosomal protein, large, P2 | -0.0384061 |
| NKTR | natural killer cell triggering receptor | -0.0382948 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0380262 |
| RPL36A | ribosomal protein L36a | -0.0380195 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0378774 |
| CSE1L | CSE1 chromosome segregation 1-like (yeast) | -0.0376174 |
| RBM39 | RNA binding motif protein 39 | -0.0375886 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0372963 |
| TPX2 | TPX2, microtubule-associated | -0.0364687 |
| MED13L | mediator complex subunit 13-like | -0.0363612 |
| UBE2K | ubiquitin-conjugating enzyme E2K | -0.0361312 |
| CANX | calnexin | -0.0358856 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0357835 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.035289 |
| TPR | translocated promoter region, nuclear basket protein | -0.0350843 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0350668 |
| RPS27A | ribosomal protein S27a | -0.034986 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0348166 |
| SCAF11 | SR-related CTD-associated factor 11 | -0.0342741 |
| RPLP0 | ribosomal protein, large, P0 | -0.0341192 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.03404 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | -0.0337539 |
| URI1 | URI1, prefoldin-like chaperone | -0.0334577 |
| B2M | beta-2-microglobulin | -0.0334164 |
| GNAS | GNAS complex locus | -0.0331878 |
| ACTG1 | actin gamma 1 | -0.0328319 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0327987 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | -0.0327452 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0327098 |
| S100A10 | S100 calcium binding protein A10 | -0.0323038 |
| TXNRD1 | thioredoxin reductase 1 | -0.0322749 |
| PRELID2 | PRELI domain containing 2 | -0.0319842 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.031971 |
| RPL4 | ribosomal protein L4 | -0.0319373 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | -0.0316553 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0314848 |
