| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Abiraterone acetate perturbation in PANC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Abiraterone acetate_PANC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VCL | vinculin | 0.130968 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.101611 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.101209 |
| ZFP36 | ZFP36 ring finger protein | 0.083295 |
| AKT2 | v-akt murine thymoma viral oncogene homolog 2 | 0.0734712 |
| EGR1 | early growth response 1 | 0.0603377 |
| PLEKHG2 | pleckstrin homology domain containing, family G (with RhoGef domain) member 2 | 0.0472095 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0405368 |
| TPM1 | tropomyosin 1 (alpha) | 0.0401199 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0393343 |
| VEGFA | vascular endothelial growth factor A | 0.0378477 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0364764 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0360011 |
| PCBP2 | poly(rC) binding protein 2 | 0.0353647 |
| SAMD4B | sterile alpha motif domain containing 4B | 0.0342681 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0340684 |
| MCL1 | myeloid cell leukemia 1 | 0.0340329 |
| MAP1B | microtubule-associated protein 1B | 0.0329476 |
| MSN | moesin | 0.0314781 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0313184 |
| L1CAM | L1 cell adhesion molecule | 0.0310915 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0283505 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0278531 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0276499 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0274667 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0269535 |
| FOSL1 | FOS-like antigen 1 | 0.0268736 |
| HSPG2 | heparan sulfate proteoglycan 2 | 0.0263843 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0263162 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | 0.0261539 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0252503 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0249736 |
| FTL | ferritin, light polypeptide | 0.024447 |
| SEPTIN9 | septin 9 | 0.0242942 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0241272 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0237299 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0235398 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0234744 |
| INTS6 | integrator complex subunit 6 | 0.0234645 |
| POTEF | POTE ankyrin domain family, member F | 0.0232735 |
| FBXO17 | F-box protein 17 | 0.0231999 |
| RPL3 | ribosomal protein L3 | 0.0229577 |
| BRD2 | bromodomain containing 2 | 0.0228509 |
| MAP3K10 | mitogen-activated protein kinase kinase kinase 10 | 0.021682 |
| CTSD | cathepsin D | 0.0215982 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0211646 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0209727 |
| TPM3 | tropomyosin 3 | 0.0201546 |
| FERMT2 | fermitin family member 2 | 0.0201037 |
| PTEN | phosphatase and tensin homolog | 0.0196277 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0195955 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0195833 |
| UBAP2 | ubiquitin associated protein 2 | 0.0195035 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0194213 |
| STC2 | stanniocalcin 2 | 0.0191222 |
| HDAC9 | histone deacetylase 9 | 0.0187831 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0186278 |
| SESN2 | sestrin 2 | 0.0183137 |
| PLEC | plectin | 0.0182001 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0178887 |
| MYO1E | myosin IE | 0.0178255 |
| PFN1 | profilin 1 | 0.0176258 |
| CCN2 | cellular communication network factor 2 | 0.0175683 |
| RNF220 | ring finger protein 220 | 0.0173106 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0171785 |
| ACTN1 | actinin, alpha 1 | 0.0169739 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0168801 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.0168575 |
| WDR27 | WD repeat domain 27 | 0.016802 |
| RTN4 | reticulon 4 | 0.0167822 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0166958 |
| MYADM | myeloid-associated differentiation marker | 0.0164259 |
| MSRB3 | methionine sulfoxide reductase B3 | 0.0162243 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0161439 |
| RASAL2 | RAS protein activator like 2 | 0.0161368 |
| HMGA2 | high mobility group AT-hook 2 | 0.0161034 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0160893 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | 0.0159392 |
| VMP1 | vacuole membrane protein 1 | 0.0158874 |
| RSU1 | Ras suppressor protein 1 | 0.0157287 |
| TNRC18 | trinucleotide repeat containing 18 | 0.0156749 |
| PRRC2A | proline-rich coiled-coil 2A | 0.015473 |
| PAF1 | Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) | 0.0154141 |
| DOCK1 | dedicator of cytokinesis 1 | 0.0154024 |
| RPS3 | ribosomal protein S3 | 0.0153072 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0151393 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | 0.0145546 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0142034 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0141579 |
| STEAP3 | STEAP family member 3, metalloreductase | 0.0140769 |
| TAPBP | TAP binding protein (tapasin) | 0.0139828 |
| LIMA1 | LIM domain and actin binding 1 | 0.0134756 |
| ADM | adrenomedullin | 0.0134408 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | 0.0133077 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | 0.0132559 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0131647 |
| RNF213 | ring finger protein 213 | 0.013145 |
| AXL | AXL receptor tyrosine kinase | 0.0131334 |
| ASTN2 | astrotactin 2 | 0.0131064 |
| NUP58 | nucleoporin 58 | 0.0128053 |
| Symbol | Name | Standardized Value |
|---|---|---|
| RPS16 | ribosomal protein S16 | -0.157085 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0775726 |
| CD44 | CD44 molecule (Indian blood group) | -0.0679827 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0606965 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0592876 |
| RPS24 | ribosomal protein S24 | -0.0533065 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0520124 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0504577 |
| ZNF292 | zinc finger protein 292 | -0.0454658 |
| SMAD3 | SMAD family member 3 | -0.0451818 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0450002 |
| TXNRD1 | thioredoxin reductase 1 | -0.0436261 |
| ACTN4 | actinin, alpha 4 | -0.0422698 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0399883 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0398885 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0397715 |
| OGA | O-GlcNAcase | -0.0375446 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0351022 |
| MORF4L2 | mortality factor 4 like 2 | -0.0344288 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0340391 |
| CANX | calnexin | -0.033511 |
| DHX32 | DEAH (Asp-Glu-Ala-His) box polypeptide 32 | -0.0321732 |
| PGK1 | phosphoglycerate kinase 1 | -0.0318704 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0316152 |
| FUS | FUS RNA binding protein | -0.0309145 |
| SMYD3 | SET and MYND domain containing 3 | -0.0301071 |
| SPAG9 | sperm associated antigen 9 | -0.0292797 |
| MYOF | myoferlin | -0.0285979 |
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) | -0.0284984 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0282368 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0274976 |
| SBF2 | SET binding factor 2 | -0.0268913 |
| RPL4 | ribosomal protein L4 | -0.0264582 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.026407 |
| PSMC4 | proteasome (prosome, macropain) 26S subunit, ATPase, 4 | -0.0263604 |
| S100A10 | S100 calcium binding protein A10 | -0.0263574 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0258563 |
| RPLP1 | ribosomal protein, large, P1 | -0.0257494 |
| RBM39 | RNA binding motif protein 39 | -0.0255757 |
| ANXA2 | annexin A2 | -0.0254674 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0251981 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.024794 |
| AHNAK | AHNAK nucleoprotein | -0.0246577 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0246005 |
| NPR2 | natriuretic peptide receptor 2 | -0.0245854 |
| TNPO1 | transportin 1 | -0.0245137 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0243597 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0240056 |
| FBL | fibrillarin | -0.0238015 |
| PRELID2 | PRELI domain containing 2 | -0.0233891 |
| ODF2L | outer dense fiber of sperm tails 2-like | -0.0233402 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | -0.0231276 |
| HNRNPL | heterogeneous nuclear ribonucleoprotein L | -0.0229977 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0227466 |
| RPL38 | ribosomal protein L38 | -0.0225034 |
| ZNF217 | zinc finger protein 217 | -0.022423 |
| RLF | rearranged L-myc fusion | -0.0218987 |
| RPL11 | ribosomal protein L11 | -0.0218283 |
| AFAP1 | actin filament associated protein 1 | -0.0218051 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0217353 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.021319 |
| SHTN1 | shootin 1 | -0.0211262 |
| ZFR | zinc finger RNA binding protein | -0.0208803 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0208399 |
| RPLP2 | ribosomal protein, large, P2 | -0.0204994 |
| APP | amyloid beta (A4) precursor protein | -0.0203854 |
| ZC3H12B | zinc finger CCCH-type containing 12B | -0.0200192 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0199825 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0199633 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0198984 |
| SENP5 | SUMO1/sentrin specific peptidase 5 | -0.0197884 |
| EFNA5 | ephrin-A5 | -0.0194891 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0194539 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0194413 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0194039 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | -0.019394 |
| CSE1L | CSE1 chromosome segregation 1-like (yeast) | -0.019225 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0191594 |
| TFRC | transferrin receptor | -0.0190468 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0188891 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0188055 |
| SEC63 | SEC63 homolog (S. cerevisiae) | -0.0187914 |
| TMEM263 | transmembrane protein 263 | -0.0186056 |
| FAM3C | family with sequence similarity 3, member C | -0.0183684 |
| RPL6 | ribosomal protein L6 | -0.0182313 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0181432 |
| TMEM123 | transmembrane protein 123 | -0.0181108 |
| RPS21 | ribosomal protein S21 | -0.0179987 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | -0.0179562 |
| GNAS | GNAS complex locus | -0.0179551 |
| RPLP0 | ribosomal protein, large, P0 | -0.0179006 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | -0.0178937 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0178704 |
| VIM | vimentin | -0.0178593 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0177697 |
| YEATS2 | YEATS domain containing 2 | -0.0177577 |
| ZFAND6 | zinc finger, AN1-type domain 6 | -0.0177024 |
| GOSR1 | golgi SNAP receptor complex member 1 | -0.0176164 |
| KIAA1328 | KIAA1328 | -0.0175811 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0175677 |
