| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Abiraterone acetate perturbation in Panc 03.27 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Abiraterone acetate_Panc 03.27 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LAMB3 | laminin, beta 3 | 0.123477 |
| MYO6 | myosin VI | 0.100139 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0991075 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0763734 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0655438 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0643105 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | 0.0636539 |
| ANXA2 | annexin A2 | 0.062107 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0573504 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0496103 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0488501 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0483261 |
| OGA | O-GlcNAcase | 0.0481391 |
| HLA-B | major histocompatibility complex, class I, B | 0.0459434 |
| NDRG1 | N-myc downstream regulated 1 | 0.0455101 |
| GOLGA4 | golgin A4 | 0.0444618 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0434598 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0428846 |
| CLIP4 | CAP-GLY domain containing linker protein family, member 4 | 0.0425968 |
| OSBPL3 | oxysterol binding protein-like 3 | 0.042177 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0418194 |
| LMO7 | LIM domain 7 | 0.0402229 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0398667 |
| AFDN | afadin, adherens junction formation factor | 0.0390442 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0383134 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | 0.036868 |
| MYO5B | myosin VB | 0.0364591 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0364582 |
| RASA2 | RAS p21 protein activator 2 | 0.0355572 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.0352135 |
| PLEC | plectin | 0.0351502 |
| PLAU | plasminogen activator, urokinase | 0.0348673 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0346968 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0344518 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0343446 |
| VCL | vinculin | 0.0340771 |
| ARRDC3 | arrestin domain containing 3 | 0.0338367 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0335054 |
| RUNX1 | runt-related transcription factor 1 | 0.0332746 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0329117 |
| MEF2A | myocyte enhancer factor 2A | 0.0329115 |
| HDLBP | high density lipoprotein binding protein | 0.032871 |
| NAV2 | neuron navigator 2 | 0.0321162 |
| TFG | TRK-fused gene | 0.0312492 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0312258 |
| HLA-C | major histocompatibility complex, class I, C | 0.0309881 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0308681 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0302005 |
| RBM26 | RNA binding motif protein 26 | 0.0299684 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0298283 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.029639 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0295349 |
| PRRC2A | proline-rich coiled-coil 2A | 0.0295332 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | 0.0292022 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0291437 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0291178 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0285466 |
| JMJD1C | jumonji domain containing 1C | 0.0277916 |
| KRT18 | keratin 18, type I | 0.0273956 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0271591 |
| TMEM123 | transmembrane protein 123 | 0.026842 |
| MAL2 | mal, T-cell differentiation protein 2 (gene/pseudogene) | 0.026659 |
| USP3 | ubiquitin specific peptidase 3 | 0.0264545 |
| FNBP1L | formin binding protein 1-like | 0.0262255 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0259617 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0258594 |
| HMGA1 | high mobility group AT-hook 1 | 0.0257771 |
| ATP13A3 | ATPase type 13A3 | 0.0254872 |
| IRF6 | interferon regulatory factor 6 | 0.0254856 |
| MYOF | myoferlin | 0.0253928 |
| CUL3 | cullin 3 | 0.0247907 |
| CCNY | cyclin Y | 0.0246075 |
| FAM3C | family with sequence similarity 3, member C | 0.024503 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0244588 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0243633 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.024244 |
| AUH | AU RNA binding protein/enoyl-CoA hydratase | 0.0241485 |
| SPAG9 | sperm associated antigen 9 | 0.0239342 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0237469 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0236154 |
| CDYL | chromodomain protein, Y-like | 0.0231886 |
| ANXA3 | annexin A3 | 0.0229777 |
| CD59 | CD59 molecule, complement regulatory protein | 0.0229191 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0228701 |
| EFHD2 | EF-hand domain family, member D2 | 0.0227159 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0225814 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0221568 |
| NEK7 | NIMA-related kinase 7 | 0.0221052 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0219562 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0217394 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0217169 |
| CD47 | CD47 molecule | 0.0216509 |
| ATP11B | ATPase, class VI, type 11B | 0.0215149 |
| NUP58 | nucleoporin 58 | 0.0214611 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0213948 |
| BCL2L1 | BCL2-like 1 | 0.0211353 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0211036 |
| RRAS2 | related RAS viral (r-ras) oncogene homolog 2 | 0.0211031 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0206531 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0203488 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.361192 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.127526 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.094511 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0920295 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0899268 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0830652 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0629463 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0620482 |
| PCLO | piccolo presynaptic cytomatrix protein | -0.0619323 |
| EGR1 | early growth response 1 | -0.0587394 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0585311 |
| KRT19 | keratin 19, type I | -0.0569868 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0531471 |
| MX1 | MX dynamin-like GTPase 1 | -0.053098 |
| RPS6 | ribosomal protein S6 | -0.0512002 |
| C3 | complement component 3 | -0.0511942 |
| EFNA5 | ephrin-A5 | -0.0506678 |
| RPS15 | ribosomal protein S15 | -0.0504687 |
| LAMA4 | laminin, alpha 4 | -0.0500245 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | -0.0491808 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0482919 |
| MX2 | MX dynamin-like GTPase 2 | -0.048265 |
| POTEF | POTE ankyrin domain family, member F | -0.0477805 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0477184 |
| FHIT | fragile histidine triad | -0.0473934 |
| RNF213 | ring finger protein 213 | -0.0460847 |
| VMP1 | vacuole membrane protein 1 | -0.045111 |
| RPS24 | ribosomal protein S24 | -0.044734 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0441159 |
| RPS23 | ribosomal protein S23 | -0.0440737 |
| KRT8 | keratin 8, type II | -0.0435803 |
| RPS29 | ribosomal protein S29 | -0.043218 |
| CCNL1 | cyclin L1 | -0.0430535 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0426292 |
| B2M | beta-2-microglobulin | -0.0422374 |
| OSMR | oncostatin M receptor | -0.0421007 |
| RIGI | RNA sensor RIG-I | -0.0410811 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.0407533 |
| PLSCR1 | phospholipid scramblase 1 | -0.040297 |
| BPTF | bromodomain PHD finger transcription factor | -0.0396161 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0391411 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0388006 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0369385 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.0364671 |
| RPL28 | ribosomal protein L28 | -0.0361572 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0359238 |
| SP100 | SP100 nuclear antigen | -0.0359034 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0357372 |
| PARP9 | poly (ADP-ribose) polymerase family, member 9 | -0.0355745 |
| PLAT | plasminogen activator, tissue | -0.0336904 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0334983 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0333445 |
| EHF | ets homologous factor | -0.0332897 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0332112 |
| DEK | DEK proto-oncogene | -0.0331047 |
| HLA-A | major histocompatibility complex, class I, A | -0.0329127 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.032675 |
| RPS5 | ribosomal protein S5 | -0.0325077 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0322078 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0316097 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0313431 |
| IFI44L | interferon-induced protein 44-like | -0.0304518 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.030294 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0300953 |
| FOXP1 | forkhead box P1 | -0.030089 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0300547 |
| MT2A | metallothionein 2A | -0.0300546 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0295994 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0294585 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0294071 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0293045 |
| RPLP2 | ribosomal protein, large, P2 | -0.0292538 |
| RPLP1 | ribosomal protein, large, P1 | -0.029211 |
| RPS13 | ribosomal protein S13 | -0.0291896 |
| EZR | ezrin | -0.028566 |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | -0.0282104 |
| SKIL | SKI-like proto-oncogene | -0.0280875 |
| ETV6 | ets variant 6 | -0.0279393 |
| TGM2 | transglutaminase 2 | -0.027761 |
| DUSP5 | dual specificity phosphatase 5 | -0.027729 |
| RPS19 | ribosomal protein S19 | -0.0277165 |
| RPL8 | ribosomal protein L8 | -0.0276472 |
| TAPBP | TAP binding protein (tapasin) | -0.0276462 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0274019 |
| RPS8 | ribosomal protein S8 | -0.0273926 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0273702 |
| RPL31 | ribosomal protein L31 | -0.0273424 |
| TXNIP | thioredoxin interacting protein | -0.0265319 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0262261 |
| RAD51B | RAD51 paralog B | -0.0260337 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0259341 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0258389 |
| RPL23 | ribosomal protein L23 | -0.0257322 |
| RPL7A | ribosomal protein L7a | -0.0253924 |
| SMYD3 | SET and MYND domain containing 3 | -0.0253664 |
| RPL19 | ribosomal protein L19 | -0.0252611 |
| USP34 | ubiquitin specific peptidase 34 | -0.0248855 |
| RPS25 | ribosomal protein S25 | -0.0247849 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0247294 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0245801 |