| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Abiraterone acetate perturbation in RKO cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Abiraterone acetate_RKO drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LAMB3 | laminin, beta 3 | 0.0846233 |
| FLNB | filamin B, beta | 0.0622176 |
| ARHGAP22 | Rho GTPase activating protein 22 | 0.0542667 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0490699 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0458569 |
| NAV2 | neuron navigator 2 | 0.0439959 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0433895 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0430557 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.042391 |
| FRMD6 | FERM domain containing 6 | 0.0414454 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.0400622 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0392512 |
| MCL1 | myeloid cell leukemia 1 | 0.0386265 |
| SAMD12 | sterile alpha motif domain containing 12 | 0.0351347 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0348492 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0344856 |
| DENND1A | DENN/MADD domain containing 1A | 0.0335252 |
| HMGA2 | high mobility group AT-hook 2 | 0.0334314 |
| FLNA | filamin A, alpha | 0.032354 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | 0.0319612 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0317635 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0312754 |
| RPL3 | ribosomal protein L3 | 0.0307513 |
| CEP250 | centrosomal protein 250kDa | 0.0306835 |
| PRRC2A | proline-rich coiled-coil 2A | 0.0293724 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.029045 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0287208 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0286951 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0279682 |
| LARGE1 | LARGE xylosyl- and glucuronyltransferase 1 | 0.0276091 |
| COL27A1 | collagen, type XXVII, alpha 1 | 0.0272488 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0272196 |
| TPM3 | tropomyosin 3 | 0.0270868 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | 0.0270628 |
| MSI2 | musashi RNA-binding protein 2 | 0.0264059 |
| CRACD | capping protein inhibiting regulator of actin dynamics | 0.0256384 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0255788 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0255635 |
| NDRG1 | N-myc downstream regulated 1 | 0.0251517 |
| SMTN | smoothelin | 0.0249587 |
| CDK6 | cyclin-dependent kinase 6 | 0.0233822 |
| STX3 | syntaxin 3 | 0.0232831 |
| SURF4 | surfeit 4 | 0.0231386 |
| SLC44A1 | solute carrier family 44 (choline transporter), member 1 | 0.0229894 |
| RAD51B | RAD51 paralog B | 0.0228862 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.0221766 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0217252 |
| GALNT18 | polypeptide N-acetylgalactosaminyltransferase 18 | 0.0214001 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.021104 |
| PRRC2B | proline-rich coiled-coil 2B | 0.0209094 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0206734 |
| SLC25A6 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6 | 0.0205909 |
| HELZ2 | helicase with zinc finger 2, transcriptional coactivator | 0.020577 |
| MTAP | methylthioadenosine phosphorylase | 0.0205642 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | 0.0203612 |
| GSE1 | Gse1 coiled-coil protein | 0.0203553 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0199283 |
| PLEC | plectin | 0.0198355 |
| DST | dystonin | 0.019705 |
| BAZ1B | bromodomain adjacent to zinc finger domain, 1B | 0.0196672 |
| WWC2 | WW and C2 domain containing 2 | 0.0192977 |
| TTR | transthyretin | 0.0191796 |
| DOCK1 | dedicator of cytokinesis 1 | 0.0191755 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0189842 |
| SLC38A1 | solute carrier family 38, member 1 | 0.0187101 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0185529 |
| FRMD4A | FERM domain containing 4A | 0.0185176 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0183945 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0182925 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0182452 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0182229 |
| ATP11A | ATPase, class VI, type 11A | 0.0181123 |
| MKI67 | marker of proliferation Ki-67 | 0.0178668 |
| ANK2 | ankyrin 2, neuronal | 0.0176688 |
| CTSL | cathepsin L | 0.0176259 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | 0.0175734 |
| PLSCR1 | phospholipid scramblase 1 | 0.017523 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | 0.0174567 |
| CUX1 | cut-like homeobox 1 | 0.0172859 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0172169 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0167959 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.016694 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0166737 |
| CMIP | c-Maf inducing protein | 0.0165619 |
| RNF213 | ring finger protein 213 | 0.0164932 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0164662 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.016321 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0162387 |
| ABR | active BCR-related | 0.016052 |
| LIMA1 | LIM domain and actin binding 1 | 0.0160256 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | 0.0159925 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | 0.0159327 |
| RIGI | RNA sensor RIG-I | 0.0158557 |
| CSNK1G3 | casein kinase 1, gamma 3 | 0.0157975 |
| HDLBP | high density lipoprotein binding protein | 0.0156799 |
| PRDM16 | PR domain containing 16 | 0.0155523 |
| PLCG1 | phospholipase C, gamma 1 | 0.0155233 |
| RAB3IP | RAB3A interacting protein | 0.0154938 |
| CTIF | CBP80/20-dependent translation initiation factor | 0.0154323 |
| EFNB2 | ephrin-B2 | 0.0154127 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.224367 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.151978 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.142466 |
| ACTG1 | actin gamma 1 | -0.115599 |
| UBC | ubiquitin C | -0.107188 |
| RPS6 | ribosomal protein S6 | -0.102522 |
| POTEF | POTE ankyrin domain family, member F | -0.0917819 |
| MT2A | metallothionein 2A | -0.0821459 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0804518 |
| RPS8 | ribosomal protein S8 | -0.0664329 |
| STC1 | stanniocalcin 1 | -0.066257 |
| RPS27A | ribosomal protein S27a | -0.0644366 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0628968 |
| RPL23 | ribosomal protein L23 | -0.0601148 |
| RPL8 | ribosomal protein L8 | -0.0594116 |
| RPL12 | ribosomal protein L12 | -0.0583367 |
| RPL7A | ribosomal protein L7a | -0.0568383 |
| RPLP2 | ribosomal protein, large, P2 | -0.0554153 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | -0.0535788 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0498224 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0486755 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.0483532 |
| TMSB10 | thymosin beta 10 | -0.047942 |
| RPLP1 | ribosomal protein, large, P1 | -0.047797 |
| HMGA1 | high mobility group AT-hook 1 | -0.0474104 |
| RPL9 | ribosomal protein L9 | -0.0467707 |
| SETD5 | SET domain containing 5 | -0.0453454 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0452147 |
| RPL7 | ribosomal protein L7 | -0.0439971 |
| RPL28 | ribosomal protein L28 | -0.0436456 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0435091 |
| LDHA | lactate dehydrogenase A | -0.043456 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0434097 |
| RPS19 | ribosomal protein S19 | -0.0433016 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.0429253 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0415274 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0414037 |
| RPLP0 | ribosomal protein, large, P0 | -0.0404061 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0391437 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0391412 |
| PTMA | prothymosin, alpha | -0.0389714 |
| CREB5 | cAMP responsive element binding protein 5 | -0.0388064 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0387269 |
| ZFR | zinc finger RNA binding protein | -0.0367647 |
| FTL | ferritin, light polypeptide | -0.0366942 |
| RPL32 | ribosomal protein L32 | -0.036501 |
| JMJD1C | jumonji domain containing 1C | -0.0363245 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.0361173 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0358851 |
| TMEM87A | transmembrane protein 87A | -0.0357567 |
| RPS11 | ribosomal protein S11 | -0.0355661 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.035162 |
| RPS5 | ribosomal protein S5 | -0.0349532 |
| JUN | jun proto-oncogene | -0.0347716 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0346756 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0346606 |
| SBF2 | SET binding factor 2 | -0.0345363 |
| PGK1 | phosphoglycerate kinase 1 | -0.0343411 |
| PTK2 | protein tyrosine kinase 2 | -0.0338468 |
| CDK17 | cyclin-dependent kinase 17 | -0.0336578 |
| TPD52 | tumor protein D52 | -0.0333258 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0333231 |
| TOP1 | topoisomerase (DNA) I | -0.033042 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0325579 |
| RPS23 | ribosomal protein S23 | -0.0324487 |
| RPS25 | ribosomal protein S25 | -0.032357 |
| RBM39 | RNA binding motif protein 39 | -0.0313865 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0312322 |
| BRD4 | bromodomain containing 4 | -0.0310819 |
| USP15 | ubiquitin specific peptidase 15 | -0.0309551 |
| PIAS1 | protein inhibitor of activated STAT, 1 | -0.0308803 |
| RASA2 | RAS p21 protein activator 2 | -0.0306281 |
| PHIP | pleckstrin homology domain interacting protein | -0.0305775 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0304427 |
| RPL19 | ribosomal protein L19 | -0.0304162 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0303174 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0301921 |
| YAP1 | Yes-associated protein 1 | -0.0300783 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0298111 |
| RPL30 | ribosomal protein L30 | -0.0297333 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | -0.029727 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.0297054 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0293075 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0291502 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0291352 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | -0.029125 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0291061 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -0.029084 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.02903 |
| GOLGA4 | golgin A4 | -0.0288828 |
| DENND4A | DENN/MADD domain containing 4A | -0.0288626 |
| RPS16 | ribosomal protein S16 | -0.0288124 |
| RPS15 | ribosomal protein S15 | -0.0287747 |
| AHNAK | AHNAK nucleoprotein | -0.0286623 |
| PTBP2 | polypyrimidine tract binding protein 2 | -0.0284945 |
| DIAPH3 | diaphanous-related formin 3 | -0.028455 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0283871 |
| RPL5 | ribosomal protein L5 | -0.0281702 |
| USP34 | ubiquitin specific peptidase 34 | -0.0281409 |
| COG5 | component of oligomeric golgi complex 5 | -0.0280387 |
