| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Abiraterone acetate perturbation in RPMI-7951 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Abiraterone acetate_RPMI-7951 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NDRG1 | N-myc downstream regulated 1 | 0.118657 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0578884 |
| ZNF292 | zinc finger protein 292 | 0.0562868 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0551212 |
| MT2A | metallothionein 2A | 0.0514414 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0454934 |
| RTN4 | reticulon 4 | 0.0453609 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0437362 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0433563 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0430828 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0404648 |
| XPO1 | exportin 1 | 0.0397137 |
| MSN | moesin | 0.0388822 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0379134 |
| CD109 | CD109 molecule | 0.0368451 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0358543 |
| VEGFA | vascular endothelial growth factor A | 0.0357053 |
| CCNL1 | cyclin L1 | 0.0350193 |
| GOLGA4 | golgin A4 | 0.0342366 |
| NUP58 | nucleoporin 58 | 0.0341784 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0340263 |
| PKM | pyruvate kinase, muscle | 0.0336666 |
| TFG | TRK-fused gene | 0.0333729 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0329455 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0329014 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0323765 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0312599 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0310281 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.030925 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 0.0306264 |
| ARRDC3 | arrestin domain containing 3 | 0.0305842 |
| PCBP2 | poly(rC) binding protein 2 | 0.0303678 |
| TGM2 | transglutaminase 2 | 0.0302903 |
| RBM39 | RNA binding motif protein 39 | 0.0300608 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0289528 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0289061 |
| POTEF | POTE ankyrin domain family, member F | 0.0288169 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0285581 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0274934 |
| CENPF | centromere protein F, 350/400kDa | 0.0269192 |
| FKBP1A | FK506 binding protein 1A, 12kDa | 0.0265401 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0264467 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0245819 |
| HELZ | helicase with zinc finger | 0.0244271 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0238822 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0236356 |
| SRP54 | signal recognition particle 54kDa | 0.0236234 |
| FAM162A | family with sequence similarity 162, member A | 0.0232313 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.0231063 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0231009 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0229385 |
| FAM13A | family with sequence similarity 13, member A | 0.0229097 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.022676 |
| ZNF148 | zinc finger protein 148 | 0.0225021 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | 0.0223241 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0220382 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.021837 |
| RNMT | RNA (guanine-7-) methyltransferase | 0.02117 |
| NPTN | neuroplastin | 0.0209827 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0209484 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0209083 |
| TPX2 | TPX2, microtubule-associated | 0.0207915 |
| ACTN4 | actinin, alpha 4 | 0.020118 |
| LDHA | lactate dehydrogenase A | 0.0201147 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0198681 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0196237 |
| NOP58 | NOP58 ribonucleoprotein | 0.0196107 |
| INSIG2 | insulin induced gene 2 | 0.0195766 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0194889 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0194704 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0191171 |
| HMGB2 | high mobility group box 2 | 0.0189584 |
| YEATS2 | YEATS domain containing 2 | 0.0189096 |
| RLF | rearranged L-myc fusion | 0.0188811 |
| COPA | coatomer protein complex, subunit alpha | 0.0188471 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0186946 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0183618 |
| RYBP | RING1 and YY1 binding protein | 0.0183435 |
| SPAG9 | sperm associated antigen 9 | 0.0182134 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.018194 |
| FLNA | filamin A, alpha | 0.0181827 |
| WDR45B | WD repeat domain 45B | 0.0181128 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0181014 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0180436 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0179714 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0177871 |
| BRD2 | bromodomain containing 2 | 0.0175099 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0172231 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0172174 |
| USP37 | ubiquitin specific peptidase 37 | 0.0171725 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.017082 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0169218 |
| AP2M1 | adaptor-related protein complex 2, mu 1 subunit | 0.0168884 |
| ADM | adrenomedullin | 0.0168264 |
| LMNA | lamin A/C | 0.0167057 |
| YBX1 | Y box binding protein 1 | 0.0166518 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0165268 |
| MATR3 | matrin 3 | 0.0165105 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0164703 |
| TPM3 | tropomyosin 3 | 0.0164266 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.162389 |
| HLA-B | major histocompatibility complex, class I, B | -0.102489 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0948816 |
| FRMD4A | FERM domain containing 4A | -0.0879968 |
| COL1A1 | collagen, type I, alpha 1 | -0.0874919 |
| CDH13 | cadherin 13 | -0.0863298 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0861806 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0834464 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0720256 |
| NAV1 | neuron navigator 1 | -0.0685684 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0607685 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0601417 |
| COL1A2 | collagen, type I, alpha 2 | -0.0577635 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0558675 |
| APCDD1L | adenomatosis polyposis coli down-regulated 1-like | -0.0520323 |
| EML5 | echinoderm microtubule associated protein like 5 | -0.0502366 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0479632 |
| ASPH | aspartate beta-hydroxylase | -0.0467031 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0436359 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0423142 |
| SP100 | SP100 nuclear antigen | -0.0410584 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0405628 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0393897 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0389275 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0388888 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0381611 |
| GLIS3 | GLIS family zinc finger 3 | -0.037727 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0372669 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0367523 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0355585 |
| COL5A1 | collagen, type V, alpha 1 | -0.0351452 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0335337 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0334905 |
| MTSS1 | metastasis suppressor 1 | -0.0329041 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0328602 |
| AHNAK | AHNAK nucleoprotein | -0.0327741 |
| MMP12 | matrix metallopeptidase 12 | -0.0324197 |
| INHBA | inhibin, beta A | -0.032019 |
| TMSB10 | thymosin beta 10 | -0.0319313 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0318861 |
| HLA-C | major histocompatibility complex, class I, C | -0.0305284 |
| JARID2 | jumonji, AT rich interactive domain 2 | -0.0303483 |
| RAI14 | retinoic acid induced 14 | -0.0301135 |
| TPM1 | tropomyosin 1 (alpha) | -0.0299404 |
| TNNC1 | troponin C type 1 (slow) | -0.0294223 |
| B2M | beta-2-microglobulin | -0.0288854 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0288118 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0286938 |
| HLA-A | major histocompatibility complex, class I, A | -0.0286303 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0283691 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0281814 |
| LOXL2 | lysyl oxidase-like 2 | -0.0281539 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0275505 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0271535 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.026889 |
| NRP1 | neuropilin 1 | -0.0267864 |
| EGFR | epidermal growth factor receptor | -0.0267334 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0264891 |
| TMEM178B | transmembrane protein 178B | -0.0262252 |
| VIM | vimentin | -0.0259545 |
| HMGA2 | high mobility group AT-hook 2 | -0.0259241 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0258392 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0256531 |
| IL1B | interleukin 1, beta | -0.025454 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0250489 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0249476 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0249087 |
| FHIT | fragile histidine triad | -0.0247725 |
| COL5A3 | collagen, type V, alpha 3 | -0.024708 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0242452 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0240012 |
| RFX8 | RFX family member 8, lacking RFX DNA binding domain | -0.023598 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0234527 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0232186 |
| TNS3 | tensin 3 | -0.0232006 |
| EXOC4 | exocyst complex component 4 | -0.0231945 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0230333 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0229549 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0227812 |
| FAM20C | family with sequence similarity 20, member C | -0.0226872 |
| XAF1 | XIAP associated factor 1 | -0.0226184 |
| SMYD3 | SET and MYND domain containing 3 | -0.0226088 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0223317 |
| ITGA1 | integrin, alpha 1 | -0.0222571 |
| ADAM12 | ADAM metallopeptidase domain 12 | -0.0222368 |
| CUX1 | cut-like homeobox 1 | -0.0222036 |
| PCBP3 | poly(rC) binding protein 3 | -0.0220814 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0219231 |
| HDAC9 | histone deacetylase 9 | -0.0217053 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0215804 |
| VCL | vinculin | -0.0215467 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0212105 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0211596 |
| FBN1 | fibrillin 1 | -0.0210907 |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 | -0.0209001 |
| MAP4 | microtubule-associated protein 4 | -0.0207466 |
| DST | dystonin | -0.0206436 |
| OXR1 | oxidation resistance 1 | -0.0204514 |
| CHD9 | chromodomain helicase DNA binding protein 9 | -0.0203374 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.020324 |
