| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Abiraterone acetate perturbation in SHP-77 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Abiraterone acetate_SHP-77 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ADARB2 | adenosine deaminase, RNA-specific, B2 (non-functional) | 0.0309118 |
| VGF | VGF nerve growth factor inducible | 0.028682 |
| PDE10A | phosphodiesterase 10A | 0.0183284 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0178437 |
| VEGFA | vascular endothelial growth factor A | 0.0175075 |
| GSE1 | Gse1 coiled-coil protein | 0.0161701 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0160177 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0159881 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.015685 |
| TMEM255B | transmembrane protein 255B | 0.0156205 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.015488 |
| FAT1 | FAT atypical cadherin 1 | 0.0150796 |
| RAD51B | RAD51 paralog B | 0.0144079 |
| WWOX | WW domain containing oxidoreductase | 0.0140413 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0137985 |
| SCUBE1 | signal peptide, CUB domain, EGF-like 1 | 0.0136719 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0136634 |
| IQGAP3 | IQ motif containing GTPase activating protein 3 | 0.0133068 |
| NUP58 | nucleoporin 58 | 0.0132097 |
| FKBP9 | FK506 binding protein 9, 63 kDa | 0.012981 |
| RPTOR | regulatory associated protein of MTOR, complex 1 | 0.0127712 |
| RPL3 | ribosomal protein L3 | 0.012489 |
| DPY19L1 | dpy-19-like 1 (C. elegans) | 0.0116411 |
| MSN | moesin | 0.0115785 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0112832 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0112572 |
| XPO1 | exportin 1 | 0.011165 |
| MIDEAS | mitotic deacetylase associated SANT domain protein | 0.0111245 |
| PFKP | phosphofructokinase, platelet | 0.0110779 |
| PNN | pinin, desmosome associated protein | 0.0109743 |
| CCAR2 | cell cycle and apoptosis regulator 2 | 0.0108907 |
| RIT2 | Ras-like without CAAX 2 | 0.0105935 |
| RUNX1T1 | runt-related transcription factor 1; translocated to, 1 (cyclin D-related) | 0.0105227 |
| PLXNB2 | plexin B2 | 0.0103217 |
| TPM3 | tropomyosin 3 | 0.0102731 |
| RIMBP2 | RIMS binding protein 2 | 0.0102542 |
| LRP5 | low density lipoprotein receptor-related protein 5 | 0.0101978 |
| UBE2QL1 | ubiquitin-conjugating enzyme E2Q family-like 1 | 0.00988318 |
| PLEC | plectin | 0.00984057 |
| LENG8 | leukocyte receptor cluster (LRC) member 8 | 0.00982896 |
| INTS1 | integrator complex subunit 1 | 0.00982413 |
| SFPQ | splicing factor proline/glutamine-rich | 0.00980126 |
| SRSF5 | serine/arginine-rich splicing factor 5 | 0.0096975 |
| TSR1 | TSR1, 20S rRNA accumulation, homolog (S. cerevisiae) | 0.0095666 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.00944433 |
| RNF20 | ring finger protein 20, E3 ubiquitin protein ligase | 0.00933507 |
| DPYSL3 | dihydropyrimidinase-like 3 | 0.00926364 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.00925973 |
| MAT2A | methionine adenosyltransferase II, alpha | 0.0092293 |
| GRAMD4 | GRAM domain containing 4 | 0.00921444 |
| FNIP1 | folliculin interacting protein 1 | 0.00915949 |
| DNAH5 | dynein, axonemal, heavy chain 5 | 0.00898889 |
| RNASE12 | ribonuclease, RNase A family, 12 (non-active) | 0.00895807 |
| PELP1 | proline, glutamate and leucine rich protein 1 | 0.00879765 |
| CLDND1 | claudin domain containing 1 | 0.00874132 |
| IVNS1ABP | influenza virus NS1A binding protein | 0.00873274 |
| RNF144A | ring finger protein 144A | 0.00862 |
| ZNF407 | zinc finger protein 407 | 0.0085595 |
| BTBD1 | BTB (POZ) domain containing 1 | 0.00851205 |
| VAV2 | vav 2 guanine nucleotide exchange factor | 0.00848112 |
| PARVB | parvin, beta | 0.00847056 |
| NDUFAF5 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 5 | 0.0083437 |
| ZNRF1 | zinc and ring finger 1, E3 ubiquitin protein ligase | 0.00826643 |
| IQSEC1 | IQ motif and Sec7 domain 1 | 0.00825749 |
| SF3A1 | splicing factor 3a, subunit 1, 120kDa | 0.00814845 |
| SEC23B | Sec23 homolog B (S. cerevisiae) | 0.00808804 |
| RNPS1 | RNA binding protein S1, serine-rich domain | 0.00807568 |
| KLHL2 | kelch-like family member 2 | 0.00803268 |
| MSH6 | mutS homolog 6 | 0.00796983 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.00795631 |
| SRSF1 | serine/arginine-rich splicing factor 1 | 0.00788881 |
| FBXL4 | F-box and leucine-rich repeat protein 4 | 0.00788285 |
| PLCG1 | phospholipase C, gamma 1 | 0.00784456 |
| SNX13 | sorting nexin 13 | 0.00782633 |
| CHKA | choline kinase alpha | 0.00780638 |
| KIF16B | kinesin family member 16B | 0.00775703 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0076806 |
| MTBP | MDM2 binding protein | 0.00763877 |
| MARK1 | MAP/microtubule affinity-regulating kinase 1 | 0.00761491 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.00761398 |
| ARRDC3 | arrestin domain containing 3 | 0.00760509 |
| PCDH9 | protocadherin 9 | 0.00759935 |
| FLNA | filamin A, alpha | 0.00756422 |
| ITGAV | integrin, alpha V | 0.00754259 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.00749742 |
| BPNT2 | 3'(2'), 5'-bisphosphate nucleotidase 2 | 0.00749433 |
| FAM91A1 | family with sequence similarity 91, member A1 | 0.0074929 |
| TSHZ1 | teashirt zinc finger homeobox 1 | 0.00745981 |
| DYNC2H1 | dynein, cytoplasmic 2, heavy chain 1 | 0.00743563 |
| RBM12B | RNA binding motif protein 12B | 0.00739702 |
| PCMTD2 | protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2 | 0.00736451 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.00729299 |
| NUP188 | nucleoporin 188kDa | 0.00727734 |
| ZFYVE16 | zinc finger, FYVE domain containing 16 | 0.00725497 |
| FADS2 | fatty acid desaturase 2 | 0.00718809 |
| ELK4 | ELK4, ETS-domain protein (SRF accessory protein 1) | 0.00717593 |
| KAT7 | K(lysine) acetyltransferase 7 | 0.00716577 |
| MINK1 | misshapen-like kinase 1 | 0.00711999 |
| AHR | aryl hydrocarbon receptor | 0.00710459 |
| LRIG1 | leucine-rich repeats and immunoglobulin-like domains 1 | 0.00704034 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.223248 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.166761 |
| CALCA | calcitonin-related polypeptide alpha | -0.132495 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.128547 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.112469 |
| ENO1 | enolase 1, (alpha) | -0.0997594 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0908792 |
| FTL | ferritin, light polypeptide | -0.0899246 |
| ACTG1 | actin gamma 1 | -0.074839 |
| STC1 | stanniocalcin 1 | -0.0744345 |
| RPS6 | ribosomal protein S6 | -0.0692155 |
| PEG10 | paternally expressed 10 | -0.0662238 |
| INHBA | inhibin, beta A | -0.0644735 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0616182 |
| SCG2 | secretogranin II | -0.0604413 |
| RPS8 | ribosomal protein S8 | -0.0598829 |
| NRG1 | neuregulin 1 | -0.0586065 |
| RPLP1 | ribosomal protein, large, P1 | -0.058351 |
| RPS21 | ribosomal protein S21 | -0.0566521 |
| TENM1 | teneurin transmembrane protein 1 | -0.0549569 |
| RPL8 | ribosomal protein L8 | -0.0530493 |
| CHGA | chromogranin A | -0.0522854 |
| PGK1 | phosphoglycerate kinase 1 | -0.0521867 |
| GPC6 | glypican 6 | -0.0510592 |
| RPL11 | ribosomal protein L11 | -0.0504606 |
| RPL37A | ribosomal protein L37a | -0.0501756 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.04938 |
| MAP1B | microtubule-associated protein 1B | -0.0485016 |
| RPS3 | ribosomal protein S3 | -0.047129 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0465834 |
| RPS27A | ribosomal protein S27a | -0.0462493 |
| RPL26 | ribosomal protein L26 | -0.0460586 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0459452 |
| S100A9 | S100 calcium binding protein A9 | -0.0443653 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0436509 |
| CNKSR3 | CNKSR family member 3 | -0.043276 |
| UBB | ubiquitin B | -0.0430494 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0425388 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0423405 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0417303 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0417139 |
| RAD21 | RAD21 homolog (S. pombe) | -0.04144 |
| FUS | FUS RNA binding protein | -0.041147 |
| RPS25 | ribosomal protein S25 | -0.0409156 |
| RPL19 | ribosomal protein L19 | -0.0407619 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.040737 |
| SYT1 | synaptotagmin I | -0.0406758 |
| RPL23 | ribosomal protein L23 | -0.0403855 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0402707 |
| NKAIN2 | Na+/K+ transporting ATPase interacting 2 | -0.0402159 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0400546 |
| RPL37 | ribosomal protein L37 | -0.0392514 |
| MT2A | metallothionein 2A | -0.0391322 |
| CANX | calnexin | -0.039026 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0384627 |
| GNAS | GNAS complex locus | -0.0383816 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | -0.0376663 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0376486 |
| RPS16 | ribosomal protein S16 | -0.037561 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.036527 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0364714 |
| RPL38 | ribosomal protein L38 | -0.0362394 |
| RPL7 | ribosomal protein L7 | -0.0361613 |
| RPL35 | ribosomal protein L35 | -0.0357944 |
| H1-0 | H1.0 linker histone | -0.0357496 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0357351 |
| RPLP0 | ribosomal protein, large, P0 | -0.0357146 |
| CPE | carboxypeptidase E | -0.0356319 |
| TMSB10 | thymosin beta 10 | -0.0354522 |
| RPS19 | ribosomal protein S19 | -0.035198 |
| RPL32 | ribosomal protein L32 | -0.0351852 |
| RPL5 | ribosomal protein L5 | -0.0351253 |
| RPL7A | ribosomal protein L7a | -0.034879 |
| MKI67 | marker of proliferation Ki-67 | -0.0347346 |
| FGF14 | fibroblast growth factor 14 | -0.0346247 |
| RPL31 | ribosomal protein L31 | -0.0342554 |
| ATP5F1E | ATP synthase F1 subunit epsilon | -0.0340184 |
| SNAP25 | synaptosomal-associated protein, 25kDa | -0.0336632 |
| EGR1 | early growth response 1 | -0.0334094 |
| RPL12 | ribosomal protein L12 | -0.0327062 |
| FOXC1 | forkhead box C1 | -0.0325117 |
| TMSB4X | thymosin beta 4, X-linked | -0.0320884 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0320622 |
| SRP72 | signal recognition particle 72kDa | -0.0319807 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0315667 |
| PCSK1 | proprotein convertase subtilisin/kexin type 1 | -0.0313815 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.0311862 |
| RPS29 | ribosomal protein S29 | -0.0308937 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.0305947 |
| PKM | pyruvate kinase, muscle | -0.0305546 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0298612 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | -0.0293651 |
| RPL30 | ribosomal protein L30 | -0.0293564 |
| RPS5 | ribosomal protein S5 | -0.029185 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0290727 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0287009 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0285762 |
| TXNRD1 | thioredoxin reductase 1 | -0.0283038 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0282387 |
| GRIK1 | glutamate receptor, ionotropic, kainate 1 | -0.0278655 |
