| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Abiraterone acetate perturbation in SK-MEL-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Abiraterone acetate_SK-MEL-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.0986699 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0661682 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | 0.0288815 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0279768 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | 0.0276394 |
| PRELID2 | PRELI domain containing 2 | 0.0257897 |
| CENPF | centromere protein F, 350/400kDa | 0.02438 |
| PLEC | plectin | 0.0232833 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0228399 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.022318 |
| MSN | moesin | 0.0208258 |
| FLNA | filamin A, alpha | 0.0201696 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0201531 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0181362 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0179843 |
| RPL3 | ribosomal protein L3 | 0.0177496 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0176542 |
| NAV2 | neuron navigator 2 | 0.017501 |
| ZNF697 | zinc finger protein 697 | 0.0169387 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0168757 |
| MT2A | metallothionein 2A | 0.0167689 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | 0.0164254 |
| FNIP1 | folliculin interacting protein 1 | 0.0160678 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0159674 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0159011 |
| CLIP4 | CAP-GLY domain containing linker protein family, member 4 | 0.0156268 |
| DENND1A | DENN/MADD domain containing 1A | 0.0153953 |
| FHIT | fragile histidine triad | 0.0153338 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0152566 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | 0.0151878 |
| AFDN | afadin, adherens junction formation factor | 0.0145384 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | 0.0145362 |
| DIAPH3 | diaphanous-related formin 3 | 0.0144894 |
| PRRC2A | proline-rich coiled-coil 2A | 0.0144431 |
| RASAL2 | RAS protein activator like 2 | 0.0139931 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0139198 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0137684 |
| RFX3 | regulatory factor X, 3 (influences HLA class II expression) | 0.0137178 |
| TENM1 | teneurin transmembrane protein 1 | 0.0136748 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0130535 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0129705 |
| NGLY1 | N-glycanase 1 | 0.0129614 |
| ATP13A3 | ATPase type 13A3 | 0.0129124 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.0128915 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0127726 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0127114 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0126503 |
| ZDHHC17 | zinc finger, DHHC-type containing 17 | 0.012599 |
| PPP2R3A | protein phosphatase 2, regulatory subunit B'', alpha | 0.0125752 |
| EP300 | E1A binding protein p300 | 0.0123907 |
| MAPK8 | mitogen-activated protein kinase 8 | 0.0122484 |
| GOLGA4 | golgin A4 | 0.0122243 |
| PUM3 | pumilio RNA binding family member 3 | 0.0121952 |
| GALNT18 | polypeptide N-acetylgalactosaminyltransferase 18 | 0.0119678 |
| CSNK1E | casein kinase 1, epsilon | 0.0119345 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0118588 |
| ZFYVE16 | zinc finger, FYVE domain containing 16 | 0.0118477 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0118116 |
| NDUFA10 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa | 0.0116699 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | 0.0116524 |
| CARD16 | caspase recruitment domain family, member 16 | 0.0116375 |
| MED13 | mediator complex subunit 13 | 0.0115052 |
| HDLBP | high density lipoprotein binding protein | 0.0114903 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0113288 |
| EXOC4 | exocyst complex component 4 | 0.0112335 |
| SUCO | SUN domain containing ossification factor | 0.0111391 |
| COA1 | cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae) | 0.011139 |
| UPF2 | UPF2 regulator of nonsense transcripts homolog (yeast) | 0.0110936 |
| ZNF644 | zinc finger protein 644 | 0.0110809 |
| SMC5 | structural maintenance of chromosomes 5 | 0.0109994 |
| FAM219A | family with sequence similarity 219, member A | 0.0108091 |
| HLA-C | major histocompatibility complex, class I, C | 0.0107944 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0107925 |
| XPNPEP3 | X-prolyl aminopeptidase 3, mitochondrial | 0.0107436 |
| RCOR1 | REST corepressor 1 | 0.0107316 |
| RBM26 | RNA binding motif protein 26 | 0.0104733 |
| METTL15 | methyltransferase like 15 | 0.0104657 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0104467 |
| FAF2 | Fas associated factor family member 2 | 0.010247 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | 0.0102147 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0102026 |
| KLHL29 | kelch-like family member 29 | 0.0102012 |
| TFDP2 | transcription factor Dp-2 (E2F dimerization partner 2) | 0.0101422 |
| MTMR1 | myotubularin related protein 1 | 0.0101083 |
| PRRC2B | proline-rich coiled-coil 2B | 0.00999408 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | 0.00996089 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.00967157 |
| UBE2G2 | ubiquitin-conjugating enzyme E2G 2 | 0.00965904 |
| MEGF6 | multiple EGF-like-domains 6 | 0.0096502 |
| SLC30A7 | solute carrier family 30 (zinc transporter), member 7 | 0.00958775 |
| ATRN | attractin | 0.00958446 |
| HERPUD2 | HERPUD family member 2 | 0.00957352 |
| PNN | pinin, desmosome associated protein | 0.0095728 |
| RTN4 | reticulon 4 | 0.00954913 |
| YEATS2 | YEATS domain containing 2 | 0.00951026 |
| SP3 | Sp3 transcription factor | 0.00942797 |
| PYGB | phosphorylase, glycogen; brain | 0.00938552 |
| SERGEF | secretion regulating guanine nucleotide exchange factor | 0.00935929 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | 0.00931448 |
| CNOT6 | CCR4-NOT transcription complex, subunit 6 | 0.00927185 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.140018 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0839303 |
| PTMA | prothymosin, alpha | -0.077543 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.0723169 |
| NLGN1 | neuroligin 1 | -0.0695684 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.067587 |
| ENO1 | enolase 1, (alpha) | -0.0660765 |
| SQSTM1 | sequestosome 1 | -0.0545077 |
| VIM | vimentin | -0.0530709 |
| PKM | pyruvate kinase, muscle | -0.0519581 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0518603 |
| FRMD4A | FERM domain containing 4A | -0.0479549 |
| NRG3 | neuregulin 3 | -0.0459863 |
| PGK1 | phosphoglycerate kinase 1 | -0.0437078 |
| FTL | ferritin, light polypeptide | -0.0432529 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.0429104 |
| SFTPA2 | surfactant protein A2 | -0.0427905 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0403347 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0401774 |
| B2M | beta-2-microglobulin | -0.0399279 |
| RPS3 | ribosomal protein S3 | -0.0399065 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0395937 |
| RPL35A | ribosomal protein L35a | -0.038576 |
| PMEL | premelanosome protein | -0.0345022 |
| TMSB10 | thymosin beta 10 | -0.0343677 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0342514 |
| CCND1 | cyclin D1 | -0.0337687 |
| HLA-E | major histocompatibility complex, class I, E | -0.0334789 |
| IER3 | immediate early response 3 | -0.0333945 |
| RPS24 | ribosomal protein S24 | -0.0331712 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0330352 |
| HLA-B | major histocompatibility complex, class I, B | -0.0329298 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0326704 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0318204 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0317454 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0300533 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0294359 |
| ST13 | suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) | -0.0294176 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0291911 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0288534 |
| IGF1R | insulin-like growth factor 1 receptor | -0.028268 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0277764 |
| SP100 | SP100 nuclear antigen | -0.0270541 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0269022 |
| RPL31 | ribosomal protein L31 | -0.0268722 |
| RPS23 | ribosomal protein S23 | -0.0266421 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0265619 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0261086 |
| RPLP2 | ribosomal protein, large, P2 | -0.0260563 |
| RPL38 | ribosomal protein L38 | -0.0259627 |
| RNF213 | ring finger protein 213 | -0.0258692 |
| LITAF | lipopolysaccharide-induced TNF factor | -0.0257573 |
| RPS8 | ribosomal protein S8 | -0.0256763 |
| PRAME | preferentially expressed antigen in melanoma | -0.0255387 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0254612 |
| RPL11 | ribosomal protein L11 | -0.0254141 |
| UBC | ubiquitin C | -0.0253882 |
| CTSD | cathepsin D | -0.0249217 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0243673 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0240309 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0238642 |
| RPL19 | ribosomal protein L19 | -0.0238005 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0235885 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0231335 |
| RPS25 | ribosomal protein S25 | -0.0229906 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0229329 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0229213 |
| CANX | calnexin | -0.0227576 |
| RPS29 | ribosomal protein S29 | -0.0227147 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0224203 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0222149 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0220924 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.022085 |
| RPS14 | ribosomal protein S14 | -0.0220347 |
| CTSB | cathepsin B | -0.0220049 |
| LSAMP | limbic system-associated membrane protein | -0.0219307 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.0218889 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0217218 |
| RPS13 | ribosomal protein S13 | -0.0215041 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.021456 |
| FUS | FUS RNA binding protein | -0.0212059 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0208636 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0208106 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0206665 |
| CCDC47 | coiled-coil domain containing 47 | -0.020394 |
| RPL28 | ribosomal protein L28 | -0.0203223 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0202568 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0202048 |
| POLR2F | polymerase (RNA) II (DNA directed) polypeptide F | -0.0201044 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0197247 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0195833 |
| MORF4L2 | mortality factor 4 like 2 | -0.0190266 |
| RPL37A | ribosomal protein L37a | -0.018872 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | -0.0186813 |
| RPLP1 | ribosomal protein, large, P1 | -0.018508 |
| APOD | apolipoprotein D | -0.0184696 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | -0.0183992 |
| NDRG1 | N-myc downstream regulated 1 | -0.0183898 |
| GNAS | GNAS complex locus | -0.0182953 |
| RPS15 | ribosomal protein S15 | -0.018093 |
