| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Abiraterone acetate perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Abiraterone acetate_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EEF2 | eukaryotic translation elongation factor 2 | 0.165788 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.11597 |
| VCL | vinculin | 0.111564 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.105225 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0990463 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0915152 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.080674 |
| FOXP1 | forkhead box P1 | 0.0748166 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0656161 |
| CALR | calreticulin | 0.0638161 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0591886 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0583091 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | 0.0576947 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0575318 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0550885 |
| ACTG1 | actin gamma 1 | 0.0514432 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0514418 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0511557 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | 0.0482871 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0469492 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0455173 |
| HDLBP | high density lipoprotein binding protein | 0.0440444 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0439419 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0396978 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0395415 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0387036 |
| PER1 | period circadian clock 1 | 0.0384745 |
| ELOVL5 | ELOVL fatty acid elongase 5 | 0.0381784 |
| FBLN2 | fibulin 2 | 0.0380601 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0377827 |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 | 0.0372109 |
| MATR3 | matrin 3 | 0.0367249 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0356783 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0353463 |
| LOXL3 | lysyl oxidase-like 3 | 0.035254 |
| AMOTL2 | angiomotin like 2 | 0.034828 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0347658 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0344957 |
| NUP58 | nucleoporin 58 | 0.0342061 |
| PLXNA1 | plexin A1 | 0.033429 |
| RPL35A | ribosomal protein L35a | 0.0326986 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0326052 |
| PRRC2A | proline-rich coiled-coil 2A | 0.0325275 |
| GNAS | GNAS complex locus | 0.0320461 |
| HLA-C | major histocompatibility complex, class I, C | 0.0318039 |
| PCBP2 | poly(rC) binding protein 2 | 0.0313794 |
| NFKB2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) | 0.031203 |
| RBM8A | RNA binding motif protein 8A | 0.0302488 |
| UNC13A | unc-13 homolog A (C. elegans) | 0.0298526 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0295126 |
| FASN | fatty acid synthase | 0.029486 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0292518 |
| SLC25A6 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6 | 0.0290748 |
| OAZ1 | ornithine decarboxylase antizyme 1 | 0.0282612 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.0280372 |
| MSI2 | musashi RNA-binding protein 2 | 0.0276719 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0275124 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0268918 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0266724 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0265981 |
| TMSB10 | thymosin beta 10 | 0.0265908 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.026463 |
| CAMKMT | calmodulin-lysine N-methyltransferase | 0.0261707 |
| PLEKHA4 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 | 0.0249414 |
| RNF213 | ring finger protein 213 | 0.0247396 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0246229 |
| WDR45B | WD repeat domain 45B | 0.0245482 |
| NEBL | nebulette | 0.0245303 |
| ACACA | acetyl-CoA carboxylase alpha | 0.0243632 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.024363 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0242879 |
| ECT2 | epithelial cell transforming 2 | 0.0241483 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | 0.024018 |
| PFN1 | profilin 1 | 0.023878 |
| MLEC | malectin | 0.0238244 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0237871 |
| TPI1 | triosephosphate isomerase 1 | 0.0236714 |
| RPL3 | ribosomal protein L3 | 0.0236695 |
| SMG7 | SMG7 nonsense mediated mRNA decay factor | 0.0236546 |
| GCNT1 | glucosaminyl (N-acetyl) transferase 1, core 2 | 0.0236212 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0233547 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0231658 |
| DIAPH2 | diaphanous-related formin 2 | 0.0231308 |
| TUBB | tubulin, beta class I | 0.0230231 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0229701 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0229142 |
| CYP51A1 | cytochrome P450, family 51, subfamily A, polypeptide 1 | 0.0228336 |
| EBNA1BP2 | EBNA1 binding protein 2 | 0.0226677 |
| SAFB2 | scaffold attachment factor B2 | 0.0225661 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0224048 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.0222651 |
| TMSB4X | thymosin beta 4, X-linked | 0.0221957 |
| FAT1 | FAT atypical cadherin 1 | 0.0219646 |
| MYO5C | myosin VC | 0.0218396 |
| RPL23 | ribosomal protein L23 | 0.0217817 |
| HELZ | helicase with zinc finger | 0.0217488 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0217368 |
| GSE1 | Gse1 coiled-coil protein | 0.0217082 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.0216316 |
| FLNA | filamin A, alpha | 0.021591 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.270855 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.222905 |
| PTMA | prothymosin, alpha | -0.15438 |
| ADAM10 | ADAM metallopeptidase domain 10 | -0.0993892 |
| RPS6 | ribosomal protein S6 | -0.072275 |
| RPS2 | ribosomal protein S2 | -0.0566951 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0549669 |
| TXNRD1 | thioredoxin reductase 1 | -0.0533748 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0529006 |
| FLNB | filamin B, beta | -0.0492931 |
| USP34 | ubiquitin specific peptidase 34 | -0.0450426 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0428771 |
| BMP2K | BMP2 inducible kinase | -0.0414354 |
| TMEM65 | transmembrane protein 65 | -0.0411273 |
| JMJD1C | jumonji domain containing 1C | -0.0397482 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0391229 |
| ATP9B | ATPase, class II, type 9B | -0.0377258 |
| SQSTM1 | sequestosome 1 | -0.036463 |
| SETD5 | SET domain containing 5 | -0.0343699 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | -0.0320301 |
| RPL26 | ribosomal protein L26 | -0.0313787 |
| RTN4 | reticulon 4 | -0.0311541 |
| CCND1 | cyclin D1 | -0.031133 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0310636 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.0303415 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0302763 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.029425 |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) | -0.0285215 |
| RAB27B | RAB27B, member RAS oncogene family | -0.0283307 |
| TCF12 | transcription factor 12 | -0.0280933 |
| ZNF217 | zinc finger protein 217 | -0.0278381 |
| MAPK8 | mitogen-activated protein kinase 8 | -0.0272713 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0265642 |
| RPL7A | ribosomal protein L7a | -0.026178 |
| TMCO3 | transmembrane and coiled-coil domains 3 | -0.0251586 |
| S100A6 | S100 calcium binding protein A6 | -0.025108 |
| MAP4 | microtubule-associated protein 4 | -0.0248936 |
| SBF2 | SET binding factor 2 | -0.024806 |
| RPL9 | ribosomal protein L9 | -0.0246948 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0245612 |
| AHI1 | Abelson helper integration site 1 | -0.0244426 |
| ANXA1 | annexin A1 | -0.0243545 |
| DUSP4 | dual specificity phosphatase 4 | -0.0238624 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0236597 |
| DENND4A | DENN/MADD domain containing 4A | -0.0231965 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0231835 |
| TRIM24 | tripartite motif containing 24 | -0.0230377 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -0.0227984 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | -0.0226734 |
| NKTR | natural killer cell triggering receptor | -0.0226674 |
| ANO6 | anoctamin 6 | -0.0226423 |
| FNIP1 | folliculin interacting protein 1 | -0.0226076 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0225676 |
| GOLGA4 | golgin A4 | -0.0224428 |
| MAP3K14 | mitogen-activated protein kinase kinase kinase 14 | -0.0222456 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | -0.0222131 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0222068 |
| GOLGB1 | golgin B1 | -0.0221764 |
| NBEAL1 | neurobeachin-like 1 | -0.0220917 |
| SHTN1 | shootin 1 | -0.0217826 |
| TFDP2 | transcription factor Dp-2 (E2F dimerization partner 2) | -0.0216558 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | -0.0216339 |
| SMYD3 | SET and MYND domain containing 3 | -0.0215845 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | -0.021575 |
| TASOR2 | transcription activation suppressor family member 2 | -0.0213879 |
| METTL15 | methyltransferase like 15 | -0.021241 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | -0.0211349 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0211207 |
| VMP1 | vacuole membrane protein 1 | -0.0211167 |
| FER | fer (fps/fes related) tyrosine kinase | -0.0209541 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0209155 |
| PRELID2 | PRELI domain containing 2 | -0.0208661 |
| H1-4 | H1.4 linker histone, cluster member | -0.0207971 |
| RPS23 | ribosomal protein S23 | -0.0206412 |
| SCFD1 | sec1 family domain containing 1 | -0.0204673 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0203296 |
| GPHN | gephyrin | -0.0202972 |
| S100A10 | S100 calcium binding protein A10 | -0.0202229 |
| CDK13 | cyclin-dependent kinase 13 | -0.0201206 |
| CLTC | clathrin, heavy chain (Hc) | -0.0200667 |
| RASAL2 | RAS protein activator like 2 | -0.0200101 |
| RPS15 | ribosomal protein S15 | -0.0199761 |
| CLIC4 | chloride intracellular channel 4 | -0.019954 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0197932 |
| KIAA2026 | KIAA2026 | -0.0196296 |
| ZNF608 | zinc finger protein 608 | -0.019535 |
| AHNAK | AHNAK nucleoprotein | -0.0195144 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0194552 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0193744 |
| PHF20 | PHD finger protein 20 | -0.0192562 |
| EVI5 | ecotropic viral integration site 5 | -0.0191687 |
| RFX7 | regulatory factor X, 7 | -0.0190059 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0189451 |
| NCKAP1 | NCK-associated protein 1 | -0.0189305 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | -0.0189055 |
| UBC | ubiquitin C | -0.0188982 |
| RPL36A | ribosomal protein L36a | -0.0186753 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.0182168 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0181356 |
| SOX6 | SRY (sex determining region Y)-box 6 | -0.0181072 |
