| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Abiraterone acetate perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Abiraterone acetate_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.107715 |
| COL6A3 | collagen, type VI, alpha 3 | 0.104659 |
| FN1 | fibronectin 1 | 0.0949297 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0861891 |
| VCAN | versican | 0.0821994 |
| NDRG1 | N-myc downstream regulated 1 | 0.0821794 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0809188 |
| FRMD4A | FERM domain containing 4A | 0.0794111 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0741127 |
| GRIN2A | glutamate receptor, ionotropic, N-methyl D-aspartate 2A | 0.0668718 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0605289 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | 0.0603832 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0540012 |
| VEGFA | vascular endothelial growth factor A | 0.0510143 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0490511 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0469395 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0427058 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0413414 |
| FLNA | filamin A, alpha | 0.0405116 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0389239 |
| ANXA2 | annexin A2 | 0.0386995 |
| CANX | calnexin | 0.0384411 |
| GLIS3 | GLIS family zinc finger 3 | 0.0378548 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.037224 |
| RNF213 | ring finger protein 213 | 0.036589 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0365174 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0359948 |
| DIAPH2 | diaphanous-related formin 2 | 0.0359092 |
| TMSB4X | thymosin beta 4, X-linked | 0.0350111 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0346347 |
| CALR | calreticulin | 0.0344413 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | 0.0342554 |
| JUN | jun proto-oncogene | 0.0341452 |
| IER3 | immediate early response 3 | 0.0331033 |
| SFRP1 | secreted frizzled-related protein 1 | 0.0330287 |
| PHF21A | PHD finger protein 21A | 0.0321284 |
| LDHA | lactate dehydrogenase A | 0.0317079 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0316175 |
| CDH13 | cadherin 13 | 0.0315025 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0309393 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0307886 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0305235 |
| STC2 | stanniocalcin 2 | 0.0299273 |
| FRMPD4 | FERM and PDZ domain containing 4 | 0.0299001 |
| PGK1 | phosphoglycerate kinase 1 | 0.0298227 |
| COL5A1 | collagen, type V, alpha 1 | 0.0297659 |
| FBXO32 | F-box protein 32 | 0.0296341 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0296228 |
| RAI14 | retinoic acid induced 14 | 0.0294187 |
| SQSTM1 | sequestosome 1 | 0.0293841 |
| HLA-A | major histocompatibility complex, class I, A | 0.028956 |
| CTSD | cathepsin D | 0.028826 |
| THBS2 | thrombospondin 2 | 0.0285471 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.028055 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0278501 |
| SFTPA2 | surfactant protein A2 | 0.0278079 |
| AHNAK | AHNAK nucleoprotein | 0.0269622 |
| RPS4X | ribosomal protein S4, X-linked | 0.0268265 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0266901 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0265955 |
| CADM1 | cell adhesion molecule 1 | 0.0255997 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0255826 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | 0.0243731 |
| NCKAP5 | NCK-associated protein 5 | 0.0241841 |
| WDR45B | WD repeat domain 45B | 0.0238719 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0234684 |
| COL1A1 | collagen, type I, alpha 1 | 0.0232978 |
| HLA-C | major histocompatibility complex, class I, C | 0.0231152 |
| TPM4 | tropomyosin 4 | 0.0231043 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0230651 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0225363 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0225182 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0225158 |
| CTSB | cathepsin B | 0.0224543 |
| NEK6 | NIMA-related kinase 6 | 0.0223996 |
| HLA-E | major histocompatibility complex, class I, E | 0.0221347 |
| SLC25A6 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6 | 0.0219289 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0219091 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0212413 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0211072 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | 0.0210893 |
| DDIT3 | DNA-damage-inducible transcript 3 | 0.0209707 |
| CCBE1 | collagen and calcium binding EGF domains 1 | 0.0208968 |
| TENM2 | teneurin transmembrane protein 2 | 0.0207474 |
| HMGA2 | high mobility group AT-hook 2 | 0.0206437 |
| COL6A1 | collagen, type VI, alpha 1 | 0.0205566 |
| UBE2O | ubiquitin-conjugating enzyme E2O | 0.0204928 |
| SLC38A1 | solute carrier family 38, member 1 | 0.0203786 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | 0.0202797 |
| CEP250 | centrosomal protein 250kDa | 0.0199123 |
| LOX | lysyl oxidase | 0.0190966 |
| TRAM2 | translocation associated membrane protein 2 | 0.0190584 |
| INTS6 | integrator complex subunit 6 | 0.0190226 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0188606 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0186114 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.0184468 |
| PRELID2 | PRELI domain containing 2 | 0.0180871 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0179588 |
| TULP4 | tubby like protein 4 | 0.0178755 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.017826 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.21151 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.16504 |
| CD44 | CD44 molecule (Indian blood group) | -0.124835 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.111478 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0889117 |
| MT2A | metallothionein 2A | -0.0854132 |
| FNDC3B | fibronectin type III domain containing 3B | -0.084677 |
| NAV2 | neuron navigator 2 | -0.0839403 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0777171 |
| MKI67 | marker of proliferation Ki-67 | -0.0737307 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0633272 |
| RPS2 | ribosomal protein S2 | -0.0581863 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0564497 |
| RPS6 | ribosomal protein S6 | -0.0563065 |
| MSN | moesin | -0.0555816 |
| SPAG9 | sperm associated antigen 9 | -0.0551687 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.053791 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.048704 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0474701 |
| JMJD1C | jumonji domain containing 1C | -0.046677 |
| KYNU | kynureninase | -0.0465124 |
| CENPF | centromere protein F, 350/400kDa | -0.0451008 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0447246 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0435813 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0431372 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0422702 |
| ANLN | anillin, actin binding protein | -0.0411436 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.040374 |
| CDCP1 | CUB domain containing protein 1 | -0.0397547 |
| STC1 | stanniocalcin 1 | -0.0385442 |
| SYAP1 | synapse associated protein 1 | -0.0375618 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0360295 |
| HLA-B | major histocompatibility complex, class I, B | -0.0359755 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0334653 |
| RPL36A | ribosomal protein L36a | -0.033422 |
| OSMR | oncostatin M receptor | -0.0326764 |
| CLTC | clathrin, heavy chain (Hc) | -0.0324145 |
| RPS8 | ribosomal protein S8 | -0.0321048 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0319327 |
| RPS12 | ribosomal protein S12 | -0.0312412 |
| BIRC2 | baculoviral IAP repeat containing 2 | -0.0307123 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | -0.0301619 |
| LAMP2 | lysosomal-associated membrane protein 2 | -0.0298809 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0298591 |
| SETD5 | SET domain containing 5 | -0.0297604 |
| GOLGA4 | golgin A4 | -0.0296483 |
| RTN4 | reticulon 4 | -0.0287574 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0287192 |
| SBF2 | SET binding factor 2 | -0.0286161 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0285329 |
| CALD1 | caldesmon 1 | -0.028033 |
| FNIP1 | folliculin interacting protein 1 | -0.0280166 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | -0.0279415 |
| RPL9 | ribosomal protein L9 | -0.027112 |
| CKAP5 | cytoskeleton associated protein 5 | -0.0266474 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0259856 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0257594 |
| BCLAF1 | BCL2-associated transcription factor 1 | -0.0254982 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0251978 |
| TNIP1 | TNFAIP3 interacting protein 1 | -0.025163 |
| PHIP | pleckstrin homology domain interacting protein | -0.024755 |
| RPL32 | ribosomal protein L32 | -0.0245208 |
| PLPP3 | phospholipid phosphatase 3 | -0.0243417 |
| DUSP5 | dual specificity phosphatase 5 | -0.0242834 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | -0.0242672 |
| FRMD5 | FERM domain containing 5 | -0.0240859 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | -0.0235317 |
| TRAF3IP2 | TRAF3 interacting protein 2 | -0.023507 |
| CHD1 | chromodomain helicase DNA binding protein 1 | -0.0234727 |
| IL6ST | interleukin 6 signal transducer | -0.0229315 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0229249 |
| RPS24 | ribosomal protein S24 | -0.0229094 |
| IGFBP7 | insulin-like growth factor binding protein 7 | -0.0226797 |
| USP47 | ubiquitin specific peptidase 47 | -0.0224641 |
| NEK7 | NIMA-related kinase 7 | -0.0222365 |
| CREB1 | cAMP responsive element binding protein 1 | -0.0221469 |
| PTMA | prothymosin, alpha | -0.0220666 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.022023 |
| BOD1L1 | biorientation of chromosomes in cell division 1-like 1 | -0.0219387 |
| PTBP2 | polypyrimidine tract binding protein 2 | -0.0218822 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.0218699 |
| CASP4 | caspase 4, apoptosis-related cysteine peptidase | -0.021706 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | -0.0216558 |
| FAM3C | family with sequence similarity 3, member C | -0.021523 |
| RBM39 | RNA binding motif protein 39 | -0.0214599 |
| NF1 | neurofibromin 1 | -0.0214468 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0214279 |
| USP9X | ubiquitin specific peptidase 9, X-linked | -0.0213578 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0213328 |
| STK17A | serine/threonine kinase 17a | -0.0213257 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0212963 |
| RPS23 | ribosomal protein S23 | -0.0211477 |
| RPLP2 | ribosomal protein, large, P2 | -0.0206766 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.020616 |
| SCFD1 | sec1 family domain containing 1 | -0.0205246 |
| CUL3 | cullin 3 | -0.0205172 |
| PRR11 | proline rich 11 | -0.0204962 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0204606 |
| KIF4A | kinesin family member 4A | -0.0203423 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0203029 |
