| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Abiraterone acetate perturbation in SW1417 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Abiraterone acetate_SW1417 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FTH1 | ferritin, heavy polypeptide 1 | 0.14724 |
| KRT18 | keratin 18, type I | 0.0712217 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | 0.0665068 |
| USP3 | ubiquitin specific peptidase 3 | 0.0483226 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0450453 |
| TMEM123 | transmembrane protein 123 | 0.0397285 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0381395 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | 0.0356353 |
| DSPP | dentin sialophosphoprotein | 0.0336895 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0324251 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0313182 |
| TFG | TRK-fused gene | 0.031246 |
| ANXA2 | annexin A2 | 0.031176 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.029231 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0289277 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.028545 |
| PUM2 | pumilio RNA-binding family member 2 | 0.028232 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0277644 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0274318 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0268995 |
| GNAS | GNAS complex locus | 0.0266677 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0266298 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0266234 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0263643 |
| NDRG1 | N-myc downstream regulated 1 | 0.0259546 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0256446 |
| MYO1B | myosin IB | 0.0249936 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0241703 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0233136 |
| SLTM | SAFB-like, transcription modulator | 0.0231918 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.022225 |
| MED13L | mediator complex subunit 13-like | 0.0219891 |
| PTMA | prothymosin, alpha | 0.0219239 |
| CLINT1 | clathrin interactor 1 | 0.0216175 |
| PGK1 | phosphoglycerate kinase 1 | 0.0215963 |
| RYK | receptor-like tyrosine kinase | 0.0211012 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0210272 |
| STT3B | STT3B, subunit of the oligosaccharyltransferase complex (catalytic) | 0.0208118 |
| UBE2C | ubiquitin-conjugating enzyme E2C | 0.020645 |
| S100A6 | S100 calcium binding protein A6 | 0.0197688 |
| IWS1 | IWS1 homolog (S. cerevisiae) | 0.0197349 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | 0.0192994 |
| MSI2 | musashi RNA-binding protein 2 | 0.0188731 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0188633 |
| SNX9 | sorting nexin 9 | 0.0185311 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0184615 |
| RASA2 | RAS p21 protein activator 2 | 0.0183214 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0178478 |
| AUH | AU RNA binding protein/enoyl-CoA hydratase | 0.0176035 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | 0.0175883 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0175738 |
| CYTH3 | cytohesin 3 | 0.0171724 |
| MYO5B | myosin VB | 0.0171642 |
| PPARG | peroxisome proliferator-activated receptor gamma | 0.0170242 |
| MTMR3 | myotubularin related protein 3 | 0.0167616 |
| EWSR1 | EWS RNA-binding protein 1 | 0.01651 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | 0.0162888 |
| MATR3 | matrin 3 | 0.016187 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0161127 |
| CYP2S1 | cytochrome P450, family 2, subfamily S, polypeptide 1 | 0.0158208 |
| U2SURP | U2 snRNP-associated SURP domain containing | 0.0157941 |
| PDCD10 | programmed cell death 10 | 0.015735 |
| CMTM7 | CKLF-like MARVEL transmembrane domain containing 7 | 0.015717 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0155564 |
| CCNY | cyclin Y | 0.015409 |
| AFDN | afadin, adherens junction formation factor | 0.0153898 |
| EIF2A | eukaryotic translation initiation factor 2A, 65kDa | 0.0151977 |
| MB21D2 | Mab-21 domain containing 2 | 0.0151879 |
| RNF145 | ring finger protein 145 | 0.0151354 |
| PRRC2A | proline-rich coiled-coil 2A | 0.0150483 |
| TMEM39A | transmembrane protein 39A | 0.0149619 |
| UBQLN1 | ubiquilin 1 | 0.0149296 |
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 | 0.0149196 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.0148322 |
| CCNT2 | cyclin T2 | 0.014741 |
| HLA-C | major histocompatibility complex, class I, C | 0.0146727 |
| ARHGAP12 | Rho GTPase activating protein 12 | 0.0146383 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0145133 |
| HELZ | helicase with zinc finger | 0.0145102 |
| WDR43 | WD repeat domain 43 | 0.0145033 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.014449 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0142982 |
| SPNS2 | spinster homolog 2 (Drosophila) | 0.0140212 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.01395 |
| FNBP1L | formin binding protein 1-like | 0.0136909 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0135547 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0134243 |
| XRN2 | 5'-3' exoribonuclease 2 | 0.0133495 |
| ASXL1 | additional sex combs like transcriptional regulator 1 | 0.01322 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.0131783 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0131399 |
| HBP1 | HMG-box transcription factor 1 | 0.0129965 |
| ZNF326 | zinc finger protein 326 | 0.0128897 |
| TCERG1 | transcription elongation regulator 1 | 0.0128599 |
| PALS2 | protein associated with LIN7 2, MAGUK p55 family member | 0.012523 |
| ATL2 | atlastin GTPase 2 | 0.0125214 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0124722 |
| YBX1 | Y box binding protein 1 | 0.0124272 |
| UIMC1 | ubiquitin interaction motif containing 1 | 0.0123189 |
| PLEC | plectin | 0.0123003 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.100476 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0933472 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.074986 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0699606 |
| MACC1 | metastasis associated in colon cancer 1 | -0.0683055 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0632766 |
| PCLO | piccolo presynaptic cytomatrix protein | -0.0592562 |
| CST3 | cystatin C | -0.0584502 |
| TMSB10 | thymosin beta 10 | -0.0552722 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0538955 |
| EZR | ezrin | -0.0530904 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0528024 |
| B2M | beta-2-microglobulin | -0.0511932 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0493433 |
| NEBL | nebulette | -0.0488258 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0482367 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0463114 |
| RPLP2 | ribosomal protein, large, P2 | -0.0438023 |
| ADNP | activity-dependent neuroprotector homeobox | -0.0418064 |
| RPLP1 | ribosomal protein, large, P1 | -0.0410971 |
| JMJD1C | jumonji domain containing 1C | -0.0389068 |
| RPS6 | ribosomal protein S6 | -0.0388667 |
| SKAP2 | src kinase associated phosphoprotein 2 | -0.0388096 |
| EGR1 | early growth response 1 | -0.038357 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0378243 |
| RPS19 | ribosomal protein S19 | -0.0377754 |
| SMYD3 | SET and MYND domain containing 3 | -0.0369291 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0368203 |
| RPL28 | ribosomal protein L28 | -0.0365068 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0361019 |
| RPS11 | ribosomal protein S11 | -0.0356588 |
| GOLGB1 | golgin B1 | -0.0351298 |
| CLDN4 | claudin 4 | -0.0346788 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.03449 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0340343 |
| RPL23 | ribosomal protein L23 | -0.0337792 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0335786 |
| USP34 | ubiquitin specific peptidase 34 | -0.033522 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0334702 |
| VCL | vinculin | -0.0329853 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.0328628 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0327153 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0311104 |
| FTL | ferritin, light polypeptide | -0.0309764 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0306881 |
| RPL7A | ribosomal protein L7a | -0.0298988 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0298261 |
| PRELID2 | PRELI domain containing 2 | -0.0295313 |
| PKP4 | plakophilin 4 | -0.0292148 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0291162 |
| RPL31 | ribosomal protein L31 | -0.0290828 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0290186 |
| BCL2L1 | BCL2-like 1 | -0.0289928 |
| RNF213 | ring finger protein 213 | -0.0286756 |
| VMP1 | vacuole membrane protein 1 | -0.028508 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0281271 |
| PLSCR1 | phospholipid scramblase 1 | -0.0276841 |
| RPL32 | ribosomal protein L32 | -0.0274652 |
| BPTF | bromodomain PHD finger transcription factor | -0.0273382 |
| ANO10 | anoctamin 10 | -0.0272058 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0265883 |
| TXNRD1 | thioredoxin reductase 1 | -0.0262183 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | -0.0261696 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | -0.0261206 |
| RPS15 | ribosomal protein S15 | -0.0260174 |
| BRD2 | bromodomain containing 2 | -0.0257123 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0256863 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0254977 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0253672 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0253203 |
| PHIP | pleckstrin homology domain interacting protein | -0.0253107 |
| FHIT | fragile histidine triad | -0.0250853 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.0250597 |
| SP100 | SP100 nuclear antigen | -0.0250307 |
| EXOC6B | exocyst complex component 6B | -0.0247598 |
| MCL1 | myeloid cell leukemia 1 | -0.024611 |
| CDK13 | cyclin-dependent kinase 13 | -0.024542 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0244421 |
| EPCAM | epithelial cell adhesion molecule | -0.0243218 |
| WNK1 | WNK lysine deficient protein kinase 1 | -0.0240998 |
| MT2A | metallothionein 2A | -0.0240979 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0237398 |
| MYO1E | myosin IE | -0.0236367 |
| MAP4 | microtubule-associated protein 4 | -0.023482 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0234698 |
| OXR1 | oxidation resistance 1 | -0.0232544 |
| HM13 | histocompatibility (minor) 13 | -0.0231636 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0231127 |
| S100A10 | S100 calcium binding protein A10 | -0.0228825 |
| FHL2 | four and a half LIM domains 2 | -0.0227266 |
| SVIL | supervillin | -0.0226723 |
| MX2 | MX dynamin-like GTPase 2 | -0.0226473 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0225667 |
| GPHN | gephyrin | -0.0225192 |
| XRN1 | 5'-3' exoribonuclease 1 | -0.0224809 |
| FUS | FUS RNA binding protein | -0.0224254 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0223705 |
| PARD3B | par-3 family cell polarity regulator beta | -0.0223347 |
| CD9 | CD9 molecule | -0.0223266 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | -0.0223263 |
